Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
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| Target ID | T59045 | Target Info | |||
| Target Name | GABA transaminase (ABAT) | ||||
| Synonyms |
L-AIBAT; Gamma-amino-N-butyrate transaminase; GABA-T; GABA-AT; GABA aminotransferase; ABAT; (S)-3-amino-2-methylpropionate transaminase
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| Target Type | Successful Target | ||||
| Gene Name | ABAT | ||||
| Biochemical Class | Transaminase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 5 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N-Phenyl-N'-carboxymethylthiourea
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Investigative | Compound Info | ||
| Synonyms |
N-Phenylthioureidoacetic acid; USAF EK-734A; 5-Phenyl-4-thiohydantoic acid; Hydantoic acid, 1-phenyl-alpha-thio-; 2-(phenylcarbamothioylamino)acetic acid; Glycine, N-(phenylthiocarbamoyl)-; U 7130; N-Phenylthiohydantoic Acid; UNII-V0HK644WMS; V0HK644WMS; 2-[(phenylcarbamothioyl)amino]acetic acid; CHEMBL311337; Glycine, N-[(phenylamino)thioxomethyl]-; WLN: T5NYMV EHJ AR& BUS; 1-Phenyl-.alpha.-thiohydantoic acid; Hydantoic acid, 1-phenyl-.alpha.-thio-; 1-Phenyl-alpha-thiohydantoic acid; NSC 4880; NSC 5570; EINECS 218-676-2; BRN 2807195; 2-(3-phenylthioureido)acetic acid; phenylthiocarbamylglycine; 0-12-00-00405 (Beilstein Handbook Reference); SCHEMBL11517574; KS-00003DVZ; DTXSID70176680; NSC4880; NSC5570; (3-Phenyl-thioureido)-acetic acid; NSC-4880; NSC-5570; ZINC5162394; BDBM50021645; delta-Phenyl-gamma-thiohydantoic acid; [(anilinocarbothioyl)amino]acetic acid; AKOS005100179; MCULE-8204338738; 2-[(anilinocarbothioyl)amino]acetic acid; Glycine, N-(phenylthiocarbamoyl)- (8CI); DS-011146; U-7130; Glycine, N-((phenylamino)thioxomethyl)- (9CI); 7X-0851; SR-01000308110; SR-01000308110-1
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| Activity |
Ki = 91000 nM
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[1] | |||
| Compound Name |
(1S,5R)-5-Aminocyclohex-3-ene-1-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL137992; BDBM50118885; ZINC13491557
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| Activity |
Ki = 100000 nM
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[2] | |||
| Compound Name |
2-Amino-cyclohex-3-enecarboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL141917; BDBM50118884; ZINC13491558; AKOS006349832
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| Activity |
Ki = 125000 nM
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[2] | |||
| Compound Name |
Paroxypropione
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Investigative | Compound Info | ||
| Synonyms |
4'-Hydroxypropiophenone; 4-Hydroxypropiophenone; 1-(4-hydroxyphenyl)propan-1-one; Mepal; p-Hydroxypropiophenone; Paroxypropion; Frenantol; Frenohypon; Profenone; Proxiphenon; Paroxon; p-Propiophenol; p-Propionylphenol; 1-Propanone, 1-(4-hydroxyphenyl)-; Hydroxypropiophenone; Hypophenon; Possipione; Sterofenon; Frenormon; Hypostat; Ibiopopp; Frenon; Bio-fren; 4-Propionylphenol; p-Oxypropiophenone; 1-(4-Hydroxyphenyl)-1-propanone; Paraoxypropiophenone; Usaf ek-3302; p-Hydroxyphenyl-1-propanone; Ethyl p-hydroxyphenyl ketone; 1-(p-Hydroxyphenyl)-1-propanone; Propiophenone, 4'-hydroxy-; 1-(4-Hydroxy-phenyl)-propan-1-one; H 365; B 360; B-360; H-365; UNII-X9952001TG; MFCD00002361; MLS000069406; CHEMBL312311; NSC-2834; X9952001TG; NCGC00018097-04; NCGC00018097-06; SMR000059092; DSSTox_CID_3426; WLN: QR DV2; DSSTox_RID_77023; DSSTox_GSID_23426; F1995-0235; Parossipropione; Paroxypropionum; Paroxipropiona; Possipion; Parossipropione [DCIT]; Paroxypropione [INN:DCF]; Paroxypropionum [INN-Latin]; Paroxipropiona [INN-Spanish]; para-Hydroxypropiophenone; NSC 2834; EINECS 200-743-2; BRN 0907511; AI3-03719; P.O.P.; 4-Propanoylphenol; p-Hydroxypropiophenon; 4-Hydroxypropiophenon; Paroxypropione (INN); 4-hydroxy propiophenone; 4`-Hydroxypropiophenone; 4'-hydroxy-propiophenone; 4''-Hydroxypropiophenone; Opera_ID_1001; ACMC-1BI1U; Ethyl 4-Hydroxyphenyl Ketone; 4-08-00-00441 (Beilstein Handbook Reference); CHLORHEXIDINEDIGLUCONATE; KSC377C7P; p-Hydroxypropiophenone (JAN); SCHEMBL440470; 4'-Hydroxypropiophenone, 98%; ZINC1890; DTXSID8023426; CTK2H7177; KS-00000BZL; NSC2834; HMS2235G15; HMS3264A14; HMS3372E08; Pharmakon1600-01506169; 1-(4-hydroxyphenyl)-propan-1-one; BCP26379; HY-B1353; NSC33949; Tox21_110822; ANW-35939; BBL011845; BDBM50177402; NSC-33949; NSC760386; s5396; SBB040250; STK397478; AKOS000120374; Tox21_110822_1; CCG-214030; CS-7973; MCULE-7251046610; NSC-760386; NCGC00018097-01; NCGC00018097-02; NCGC00018097-03; NCGC00018097-05; NCGC00022475-03; NCGC00022475-04; AC-10985; AK-44068; AS-12055; BR-44068; ST075170; SY003666; FT-0618741; C13342; D01870; M-6404; 4 inverted exclamation mark -Hydroxypropiophenone; AB00384258_14; AF-676/00077028; SR-01000002967; SR-01000002967-2; W-104544; BRD-K07441213-001-14-8; Q19598411; Z1250132262
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| Activity |
IC50 = 176000 nM
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[3] | |||
| Compound Name |
4'-Hydroxyacetophenone
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Investigative | Compound Info | ||
| Synonyms |
4-Hydroxyacetophenone; 1-(4-Hydroxyphenyl)ethanone; P-HYDROXYACETOPHENONE; 4-Acetylphenol; Piceol; Ethanone, 1-(4-hydroxyphenyl)-; p-Acetylphenol; para-Hydroxyacetophenone; p-Oxyacetophenone; Methyl p-hydroxyphenyl ketone; p-Hydroxyphenyl methyl ketone; 4-hydroxy acetophenone; Acetophenone, 4'-hydroxy-; Phenol, p-acetyl-; (4-Hydroxyphenyl)ethan-1-one; 1-(4-Hydroxyphenyl)Ethan-1-One; Acetophenone, p-hydroxy-; USAF KF-15; 4-Acetophenol; HYDROXYACETOPHENONE, PARA; 4-Hydroksyacetofenol; 1-(4-Hydroxy-phenyl)-ethanone; UNII-G1L3HT4CMH; NSC 3698; MFCD00002359; G1L3HT4CMH; 4-HYDROXYLACETOPHENONE; 4-Hydroxyphenyl Methyl Ketone; CHEMBL201083; (4-Hydroxyphenyl)-1-propanone; c0694; DSSTox_CID_9133; 1-acetyl-4-hydroxybenzene; DSSTox_RID_78678; DSSTox_GSID_29133; 4'-Hydroxyacetophenone, 98%; Methyl-p-hydroxyphenyl ketone; 4-Hydroksyacetofenol [Polish]; 4'-hydroxy acetophenone; EINECS 202-802-8; AI3-12133; p-Hydroxacetophenone; parahydroxyacetophenone; 4'-hyroxyacetophenone; p-hydroxy acetophenone; p-hydroxy-acetophenone; PubChem3311; rho-hydroxyacetophenone; P-ACETOPHENOL; PubChem13990; ACMC-209sej; 4''-hydroxyacetophenone; Acetaminophen Impurity E; 4\\'-Hydroxypropiophenone; (4-hydroxyphenyl)ethanone; bmse000593; bmse000670; bmse010030; EC 202-802-8; WLN: QR DV1; 4-HAP; ASISCHEM D38759; HYDROXYACETOPHENONE-4; SCHEMBL40866; KSC486M3B; BIDD:ER0242; 1-(4-hydroxyphenyl) ethanone; 1-(4-hydroxyphenyl)-ethanone; 4'-Hydroxyacetophenone, 99%; HYDROXYACETOPHENONE, P-; 278564_ALDRICH; AURORA 16683; PARAGOS 440062; DTXSID0029133; CTK3I6630; CTK8H8820; TIMTEC-BB SBB005399; TIMTEC-BB SBB040251; 1-(4-hydroxyphenyl)-1-ethanone; NSC3698; OTAVA-BB 1778865; LABOTEST-BB LTBB002651; ZINC330136; Acetophenone, 4'-hydroxy- (8CI); ACT01160; CS-D1120; HY-Y0073; KS-000001GC; NSC-3698; STR01114; AKOS BBS-00003226; AKOS BBS-00009026; Tox21_200228; Tox21_303602; ANW-41081; BBL011610; BDBM50177409; LABOTEST-BB LT03331896; LT0047; SBB040251; STK397448; ZINC00330136; AKOS000118915; AC-6123; AS01158; LS10359; MCULE-6065587915; NE10181; OTAVA-BB 7013941401; NCGC00248570-01; NCGC00248570-02; NCGC00257375-01; NCGC00257782-01; AK-86441; SC-07567; SY009665; 4'-Hydroxyacetophenone, analytical standard; AB0007869; FT-0618684; H6236; ST50213412; 70H702; C10700; 4 inverted exclamation mark -Hydroxyacetophenone; AB00443569-03; 1-(2-HYDROXY-5-METHYLPHENYL)-1-ETHANONE; AB-131/40179700; 4-(1-Hydroxyethylidene)-2,5-cyclohexadiene-1-one; Q7190613; W-100007; Z57040434; F0001-2341
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| Activity |
IC50 = 188000 nM
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[3] | |||
| Non Binders of This Target (in total, 19 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
BAICALEIN
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Phase 2 | Compound Info | ||
| Synonyms |
baicalein; 491-67-8; 5,6,7-Trihydroxyflavone; 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one; Noroxylin; Biacalein; BaiKalein; Baicelein; UNII-49QAH60606; NSC661431; NSC 661431; CHEMBL8260; 5,6,7-trihydroxy-2-phenylchromen-4-one; CHEBI:2979; FXNFHKRTJBSTCS-UHFFFAOYSA-N; MFCD00017459; 4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl-; 49QAH60606; 5,7-Trihydroxyflavone; 5,6,7-trihydroxy-2-phenyl-chromen-4-one; Sho-saiko-to; SMR000112462; SR-01000597499; Baicalein, 8; Baicalein,(S); 3WL; Baicalein, 14; Baicalein, 98%; AC1NQYPP; Tocris-1761
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| Activity |
IC50 = 12800000 nM
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[4] | |||
| Compound Name |
Gastrodin
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Investigative | Compound Info | ||
| Synonyms |
Gastrodine; UNII-5YS9U2W3RQ; 4-(Hydroxymethyl)phenyl beta-D-Glucopyranoside; Gastrodin Hemihydrate; 5YS9U2W3RQ; CHEMBL274739; b-D-Glucopyranoside, 4-(hydroxymethyl)phenyl; 4-(hydroxymethyl)phenyl hexopyranoside; beta-D-Glucopyranoside, 4-(hydroxymethyl)phenyl; Gastrodin,(S); Gastrodin (Gastrodine); Gastrodin(Gastrodine) /; 4-(Hydroxymethyl)phenyl-beta-D-glucopyranoside; SCHEMBL1076037; Gastrodin, >=98% (HPLC); DTXSID30978086; HMS3884L15; HY-N0115; ZINC3881790; 2424AH; ABP000694; BDBM50177403; C13H18O7.1/2H2O; MFCD00272169; s2383; (4-(hydroxymethyl)phenoxy)tetrahydro-; AKOS015951256; A-D-Glucopyranosyloxybenzyl alcohol; AC-8028; BCP9000710; CCG-267336; CS-7969; MCULE-1087767842; MCULE-7347418444; NCGC00346601-02; AS-17473; Gastrodin, from Gastrodia alata, >=98%; SC-17325; 4-[beta-d-glucopyranosyloxy] benzyl alcohol; N1710; V0273; (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-; C16964; 499G278; Q-100720; Q5526833; NCGC00346601-02_C13H18O7_beta-D-Glucopyranoside, 4-(hydroxymethyl)phenyl
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| Activity |
IC50 > 1000000 nM
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[3] | |||
| Compound Name |
Helicide
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Investigative | Compound Info | ||
| Synonyms |
Helicid; Hilicidum; 4-FORMYLPHENYL B-D-ALLOPYRANOSIDE; CHEMBL201358; 4-(BETA-D-ALLOPYRANOSYLOXY)-BENZALDEHYDE; 4-Formylphenyl beta-D-Allopyranoside; Benzaldehyde, 4-(b-D-allopyranosyloxy)-; 4-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybenzaldehyde; Helicid,(S); SCHEMBL17822698; KS-00000UQO; HMS3885A06; 4-Formylphenyl ss-D-Allopyranoside; HY-N0343; BDBM50177404; s3797; ZINC28568062; 4-beta-D-Allopyranosyloxy)benzaldehyde; AKOS025310966; CCG-267289; 4-(beta-D-Allopyranosyloxy)benzaldehyde; 4-Formylphenylbeta-D-Allopyranoside,98%; AS-30535; AB0016909; CS-0008901; F0542; 154H343
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| Activity |
IC50 > 1000000 nM
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[3] | |||
| Compound Name |
4-Aminobenzoic acid
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Investigative | Compound Info | ||
| Synonyms |
p-aminobenzoic acid; para-aminobenzoic acid; AMINOBENZOIC ACID; Vitamin BX; p-Carboxyaniline; 4-Carboxyaniline; Sunbrella; Benzoic acid, 4-amino-; p-Carboxyphenylamine; Hachemina; Paraminol; 1-Amino-4-carboxybenzene; Pabacyd; Pabafilm; Pabamine; Paranate; Amben; Potaba; Romavit; Bacterial vitamin H1; Vitamin H'; Anticanitic vitamin; Chromotrichia factor; RVPaba Lipstick; Papacidum; Rvpaba; Trichochromogenic factor; Anti-chromotrichia factor; Super Shade by Coppertone; Benzoic acid, p-amino-; Acidum paraminobenzoicum; Pabagel; Pabanol; 4-AMINO-BENZOIC ACID; Caswell No. 033B; Kyselina p-aminobenzoova; MFCD00007894; Vitamin H1; p-Aminobenzoesaeure; 4-Aminobenzoesaeure; 4-aminobenzoic-acid; 4-Carboxyphenylamine; Acido p-aminobenzoico; gamma-Aminobenzoic acid; benzoic acid, 4-amino; Acido p-aminobenzoico [Italian]; UNII-TL2TJE8QTX; Kyselina p-aminobenzoova [Czech]; para-aminobenzoate; Anticantic vitamin; EPA Pesticide Chemical Code 233300; BRN 0471605; p-amino benzoic acid; p-amino-Benzoic acid; AI3-02436; TL2TJE8QTX; Aminobenzoic acid (USP); Aminobenzoic acid [USP]; .gamma.-Aminobenzoic acid; Aniline-4-carboxylic acid; CHEMBL542; 4-Aminobenzoic acid, 99%; H-4-ABZ-OH; AMINOBENZOIC ACID, PARA; NCGC00091051-01; 4-aminobenzoicacid; DSSTox_CID_4466; DSSTox_RID_77411; DSSTox_GSID_24466; SMR000471833; CCRIS 6209; HSDB 6840; NSC 7627; EINECS 205-753-0; Actipol; p-carboxy aniline; p-aminobezoic acid; gamma-Aminobenzoate; 4-aminobezoic acid; Trochromogenic factor; Aniline-4-carboxylate; 4-Amino benzoic acid; 4-(amino)benzoic acid; Antichromotrichia factor; PubChem13422; Spectrum_000036; RVPaba lipstick (TN); P-AMINO-BENZOATE; Aminobenzoic Acid, USP; Spectrum2_000123; Spectrum3_000294; Spectrum4_000142; Spectrum5_000778; Tetracaine EP Impurity A; P-Aminobenzoic Acid,(S); ACMC-209d3t; bmse000066; bmse000887; bmse000916; Epitope ID:115017; H-(4)Abz-OH; AMINOBENZOIC-4 ACID; EC 205-753-0; SCHEMBL8249; Oprea1_221096; BSPBio_001828; KBioGR_000584; KBioSS_000396; ZINC920; KSC176C0R; MLS001066325; MLS001335919; MLS001335920; Para Amino Benzoic Acid USP; BIDD:ER0375; DivK1c_000783; SPBio_000166; PARA AMINO BENZOIC ACID; RARECHEM AL BO 0238; component of Presun (Salt/Mix); DTXSID6024466; SCHEMBL13232108; CTK0H6108; KBio1_000783; KBio2_000396; KBio2_002964; KBio2_005532; KBio3_001328; NSC7627; NINDS_000783; OTAVA-BB 1509951; P-AMINOBENZOIC ACID 100G; 150-13-0 4-aminobenzoic acid; HMS2269E10; HMS3870E13; LABOTEST-BB LTBB000459; WT266; ACT09225; HY-B1008; NSC-7627; Tox21_111069; Tox21_201702; Tox21_300087; ANW-21255; BDBM50145829; LABOTEST-BB LT03328355; s4510; SBB058665; STK397441; AKOS000118983; Tox21_111069_1; AC-8107; AM86626; AS00762; CCG-266139; CS-4505; DB02362; MCULE-3535374816; IDI1_000783; KS-0000022O; 4-Aminobenzoic acid, analytical standard; NCGC00091051-02; NCGC00091051-03; NCGC00091051-04; NCGC00253923-01; NCGC00259251-01; AK-41178; AS-12493; NCI60_041683; SC-18898; SY003749; SBI-0051277.P003; DB-028695; 4-Aminobenzoic acid, ReagentPlus(R), 99%; A0269; FT-0617557; ST50632536; 4-Aminobenzoic acid, >=98.0% (HPLC/NT); 3297-EP2308861A1; 3297-EP2308868A1; 3297-EP2311809A1; 4-Aminobenzoic acid, ReagentPlus(R), >=99%; 6761-EP1441224A2; 6761-EP2295402A2; C00568; D02456; Q-9193; 48316-EP2281563A1; 48316-EP2308874A1; 48316-EP2311494A1; Q284959; 4-Aminobenzoic acid, Vetec(TM) reagent grade, 98%; Q-200432; Z57127446; 4-Aminobenzoic acid, 98.5-100.2%, SAJ first grade; F2191-0259; 4A5E7DD8-8A22-4642-86BF-05B778C0C78E
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| Activity |
IC50 > 1000000 nM
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[3] | |||
| Compound Name |
4-Hydroxybenzyl alcohol
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Investigative | Compound Info | ||
| Synonyms |
4-(Hydroxymethyl)phenol; p-Hydroxybenzyl alcohol; p-Methylolphenol; 4-Hydroxybenzenemethanol; 4-Methylolphenol; Benzenemethanol, 4-hydroxy-; 4-Hydroxybenzylalcohol; p-(Hydroxymethyl)phenol; Gastrodigenin; Benzyl alcohol, p-hydroxy-; alpha-Hydroxy-p-cresol; MFCD00004658; Parahydroxybenzyl Alcohol; para-hydroxybenzyl alcohol; UNII-1A3AH1FP1B; .alpha.-Hydroxy-p-cresol; 1A3AH1FP1B; CHEMBL202132; Benzyl alcohol, p-hydroxy- (8CI); Benzenemethanol, 4-hydroxy- (9CI); 4-Hydroxymethyl-phenol; 4-Hydroxybenzyl alcohol, 97%; CCRIS 5114; 4-hydroxybenzyl-alcohol; p-hydroxy benzyl alcohol; EINECS 210-768-0; NSC 227926; a-hydroxy-p-cresol; 4-hydroxymethylphenol; 4-hydroxymethyl phenol; 4-(Hydroxymethyl)pheno; 4-Hydroxy-benzylalcohol; 4-Hydroxyphenyl methanol; p-hydroxy-Benzyl alcohol; 4-Hydroxyphenyl Carbinol; 4-hydroxy benzyl alcohol; 4-hydroxy-benzyl alcohol; B4-hydroxy-enzenemethanol; 4-hydroxyl-benzyl alcohol; ACMC-1BDK0; bmse000623; bmse010028; EC 210-768-0; SCHEMBL62690; KSC489M6F; ARONIS24225; PARA-HYDROXYMETHYLPHENOL; HYDROXYBENZYL-4 ALCOHOL; 4-Hydroxybenzyl alcohol, 99%; PARAGOS 420603; RARECHEM AL BD 0098; DTXSID8073920; CTK3I9662; FEMA 3987; HMS3885O08; ZINC388762; ACT01155; BCP27109; HY-Y0892; STR00674; ANW-34146; BBL025863; BDBM50177408; NSC227926; s3857; SBB059322; STL284640; AKOS000121529; 4-Hydroxybenzyl alcohol, >=98%, FG; AS00576; CCG-266090; CS-W019891; MCULE-8377025602; NSC-227926; PS-3494; KS-000000J3; KS-0000470R; AC-24727; AK-47325; BR-47325; SC-18384; SY003753; 4-(hydroxymethyl)phenol (ACD/Name 4.0); AB0010766; DB-003490; 4-Hydroxybenzyl alcohol, analytical standard; AM20050567; FT-0618701; ST45053891; 23H052; A15709; C17467; Q-200481; Q5526828; F0001-1668; 4-(Hydroxymethyl)phenol;p-Hydroxybenzyl alcohol;p-Methylolphenol
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| Activity |
IC50 > 1000000 nM
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[3] | |||
| Compound Name |
4-Hydroxybenzoic acid
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Investigative | Compound Info | ||
| Synonyms |
p-Hydroxybenzoic acid; 4-Carboxyphenol; Benzoic acid, 4-hydroxy-; p-Salicylic acid; para-Hydroxybenzoic acid; Benzoic acid, p-hydroxy-; 4-Hydroxybenzoesaeure; 4-hydroxy benzoic acid; p-Oxybenzoesaure [German]; 4-hydroxy-benzoic acid; Paraben-acid; Acido p-idrossibenzoico [Italian]; Kyselina 4-hydroxybenzoova; Kyselina 4-hydroxybenzoova [Czech]; NSC 4961; UNII-JG8Z55Y12H; 4-Hydroxybenzoicacid; HYDROXYBENZOIC ACID, PARA; p-hydroxy benzoic acid; p-hydroxy-Benzoic acid; Hydroxybenzoic acid; Hydroxybenzenecarboxylic acid; 4-HBA; HSDB 7233; CHEMBL441343; JG8Z55Y12H; EINECS 202-804-9; MFCD00002547; AI3-01003; 4-hydroxy-benzoate; DSSTox_CID_6647; DSSTox_RID_78173; DSSTox_GSID_26647; Benzoic acid, p-hydroxy; 4-Hydroxybenzoic acid, 99+%; Benzoic acid, 4-hydroxy; WLN: QVR DQ; p-Oxybenzoesaure; NSC4961; Acido p-idrossibenzoico; DB04242; NCGC00166040-01; C00156; p-Salicylate; AE-848/32195059; CCRIS 8812; p-hydroxy-Benzoate; para-salicylic acid; 4-hydoxybenzoic acid; 4-hyroxybenzoic acid; parahydroxybenzoic acid; phenol derivative, 8; 4-hydroxylbenzoic acid; 4-Hydroxy-benzoesaeure; 4-hydroxybenzoi c acid; PubChem16819; ACMC-209sel; 4-hydroxyl benzoic acid; 4-Hydroxybenzoate, III; para-hydroxy benzoic acid; Para Hydroxy Benzoic Acid; bmse000092; bmse000583; EC 202-804-9; SCHEMBL4110; KSC173K8H; BIDD:ER0706; 4-Hydroxybenzenecarboxylic acid; p-Hydroxybenzoic Acid, Reagent; Acetylsalicylic Acid Impurity A; DTXSID3026647; BDBM26194; Salicylic acid Related Compound A; LR-68; ZINC332752; CS-D1180; HY-Y0264; KS-00000O5B; NSC-4961; STR01287; Tox21_202342; Tox21_303301; AC-008; ANW-41083; BBL011981; s3754; SBB040549; STL138745; 4-Hydroxybenzoic acid, >=99%, FG; AKOS000119033; AM87513; CCG-266143; MCULE-1367764897; NE10208; NCGC00166040-02; NCGC00257058-01; NCGC00259891-01; AK106263; SC-16333; FT-0618695; FT-0669322; ST50210584; 4-Hydroxybenzoic acid, ReagentPlus(R), 99%; 4-Hydroxybenzoic acid, ReagentPlus(R), >=99%; 44643-EP2281819A1; 44643-EP2292619A1; 44643-EP2298735A1; 44643-EP2305659A1; 44643-EP2311809A1; 44643-EP2311818A1; 194587-EP2371808A1; 4-Hydroxybenzoic acid, puriss., >=99.0% (T); Q229970; 46DD083D-BFD3-4CE1-B2D9-6C6D5FEFD3D9; J-660066; W-100004; F2191-0237; Z1259273385
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| Activity |
IC50 > 1000000 nM
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[3] | |||
| Compound Name |
4-Hydroxybenzaldehyde oxime
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Investigative | Compound Info | ||
| Synonyms |
p-Hydroxybenzaldehyde oxime; 4-[(E)-(hydroxyimino)methyl]phenol; p-Hydroxybenzaldoxime; 4-Hydroxybenzaldoxime; Benzaldehyde, p-hydroxy-, oxime; Benzaldehyde, 4-hydroxy-, oxime; 4-((hydroxyimino)methyl)phenol; 4-[(hydroxyimino)methyl]phenol; CHEMBL202611; NSC30; SCHEMBL91114; (Z)-4-Hydroxybenzaldehydeoxime; ARONIS014017; NSC-30; (1E)-4-hydroxybenzaldehyde oxime; NSC61336; 6494AE; BBL023611; MFCD00019964; NSC-61336; SBB080079; STL069574; AKOS000319555; ZINC100237472; BS-17456; BB 0256552; ST45050715; T8120; EN300-53758; AF-753/00286030
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| Activity |
IC50 > 1000000 nM
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[3] | |||
| Compound Name |
4-Methoxybenzaldehyde
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Investigative | Compound Info | ||
| Synonyms |
P-ANISALDEHYDE; Anisic aldehyde; Anisaldehyde; p-Methoxybenzaldehyde; 4-Anisaldehyde; Benzaldehyde, 4-methoxy-; Aubepine; p-Anisic aldehyde; p-Formylanisole; Crategine; Obepin; para-anisaldehyde; 4-Methoxy-benzaldehyde; 4-methoxy benzaldehyde; anisal; MFCD00003385; NSC 5590; UNII-9PA5V6656V; p-methoxy benzaldehyde; CHEMBL161598; FEMA 2670; 9PA5V6656V; p-Anisaldehyde, 99+%; DSSTox_CID_6997; DSSTox_RID_78277; DSSTox_GSID_26997; Formylanisole, p-; Caswell No. 051E; p-Anisaldehyde,p-Methoxybenzaldhyde; CCRIS 821; 4-Methoxybenzaldhyde; FEMA No. 2670; p-Methoxybenzaldehyde (natural); HSDB 2641; EINECS 204-602-6; anisaldehyd; Anis aldehyde; AI3-00223; 4-methoxybenzaldehye; 4-methoxybezaldehyde; EINECS 256-891-3; Anisaldehyde (para); Anisaldehyde solution; p-Methoxybenzafdehyde; P-Anisaldehyde,(S); 4-methoxylbenzaldehyde; p-Anisaldehyde, 8CI; AN1SALDEHYDE; 4-methoxybenzylaldehyde; BRN 0471382; p-anisaldehyde solution; para-methoxybenzaldehyde; p-Anisaldehyde, 98%; PubChem22535; p-Anisaldehyde, Reagent; ACMC-1BAZN; para-methoxy benzaldehyde; 4-(methyloxy)benzaldehyde; bmse010130; WLN: VHR DO1; EC 204-602-6; SCHEMBL1100; Methoxybenzaldehyde (Related); KSC174M6D; MLS002152921; NATURAL ANISIC ALDEHYDE; p-Methoxybenzylidenemalonitrile; 4-methoxybenzene carboxaldehyde; p-Methoxy Benzaldehyde, Natural; DTXSID2026997; CTK0H4661; EBD1062; NSC5590; HMS3039F08; ZINC157146; p-Anisaldehyde, analytical standard; HY-Y0740; KS-000002NI; NSC-5590; p-Anisaldehyde, natural, 98%, FG; Tox21_201943; Tox21_303331; ANW-18100; BBL027436; BDBM50139370; s5086; SBB040224; STL194068; AKOS000118814; AS02988; CCG-214805; CS-W020189; MCULE-9537754812; p-Anisaldehyde (4-Methoxybenzaldehyde); p-Anisaldehyde, for synthesis, 98.0%; NCGC00090807-01; NCGC00090807-02; NCGC00257076-01; NCGC00259492-01; p-Anisaldehyde, >=97.5%, FCC, FG; AC-10379; AK-72956; BR-72956; CS-11005; SC-26765; SMR001224521; SY001689; DB-012818; A0480; BENZALDEHYDE,4-METHOXY MFC8 H8 O2; FT-0617622; FT-0662227; FT-0662228; ST50213373; C10761; M-6033; 29578-EP2284160A1; 29578-EP2292628A2; 29578-EP2305695A2; 29578-EP2305696A2; 29578-EP2305697A2; 29578-EP2305698A2; 29578-EP2308838A1; 29578-EP2311825A1; 29578-EP2311842A2; 79582-EP2287153A1; 79582-EP2292628A2; 79582-EP2298755A1; 79582-EP2305695A2; 79582-EP2305696A2; 79582-EP2305697A2; 79582-EP2305698A2; 79582-EP2374783A1; 79582-EP2377841A1; 4-08-00-00252 (Beilstein Handbook Reference); A805017; Q174937; Q-100105; F2190-0575
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| Activity |
IC50 > 1000000 nM
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[3] | |||
| Compound Name |
5-Amino-cyclohex-3-enecarboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL336887; SCHEMBL18071630; BDBM50118888; cis-3-aminocyclohex-4-ene-1-carboxylic acid; 5beta-Amino-3-cyclohexene-1beta-carboxylic acid
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| Activity |
Ki = 2300000 nM
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[2] | |||
| Compound Name |
2-(3-Aminophenyl)acetic acid hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL535865; SCHEMBL2884824; 2-(3-Aminophenyl)Acetic Acid HCl; NE57323; EN300-72807
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| Activity |
IC50 > 5000000 nM
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[5] | |||
| Compound Name |
2-(Aminomethyl)benzoic acid hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
2-AMINOMETHYL-BENZOIC ACID HYDROCHLORIDE; 2-(Aminomethyl)Benzoic Acid HCl; 2-Aminomethylbenzoic acid hydrochloride; CHEMBL535415; (2-benzylamino)carboxylic acid hydrochloride; SCHEMBL4542361; DTXSID60669839; 7123AC; MFCD09028989; AKOS024260955; MCULE-7214993753; SB30029; DA-16561; FT-0752261; Z-5242; 2-(Aminomethyl)-benzoic acid hydrochloride(1:1; 2-(Aminomethyl)benzoic acid hydrochloride, 95%; 2-(Aminomethyl)benzoic acid--hydrogen chloride (1/1); Benzoic acid, 2-(aminomethyl)-, hydrochloride (1:1)
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| Activity |
IC50 > 5000000 nM
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[5] | |||
| Compound Name |
3-(Aminomethyl)benzoic acid hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
3-Aminomethylbenzoic acid hydrochloride; 3-Aminomethylbenzoic acid HCl; MFCD03791117; (3-Aminomethyl) benzoic acid hydrochloride; CHEMBL541141; 3-(aminomethyl)-benzoic acid hydrochloride; ACMC-209tzp; SCHEMBL4232340; CTK7E5333; KS-00000MJY; 3-(Aminomethyl)Benzoic Acid HCl; DTXSID70585031; 3-(Aminomethyl)benzoic acid, HCl; 3-aminomethyl-benzoic acid HCl salt; ANW-43139; RW2987; SBB052654; 3-(aminomethyl)benzoic acid, chloride; AKOS004118474; CS-W001871; MCULE-3333725886; PS-8451; QC-2744; SB39275; VZ26060; 3-(Aminomethyl)benzoicacid hydrochloride; 3-aminomethyl-benzoic acid hydrochloride; 3-(aminomethyl)benzoic acid;hydrochloride; AK-36663; BR-36663; SC-28534; SY018502; AB0019102; DB-028355; AM20060744; FT-0633054; EN300-70607; S-3524; 876A039; J-511694; 3-(Aminomethyl)benzoic acid--hydrogen chloride (1/1); Z1262691668; 3-(Aminomethyl)benzoic acid hydrochloride, >=98.0% (HPLC)
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| Activity |
IC50 > 5000000 nM
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[5] | |||
| Compound Name |
2-(Aminomethyl)phenylacetic acid hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
2-(2-(aminomethyl)phenyl)acetic acid hydrochloride; (2-(Aminomethyl)phenyl)acetic acid hydrochloride; 2-[2-(aminomethyl)phenyl]acetic acid;hydrochloride; 2-AMINOMETHYLPHENYL ACETIC ACID HYDROCHLORIDE; 2-(Aminomethyl)phenylaceticacid; CHEMBL535644; EINECS 257-635-3; (2-(Aminomethyl)phenyl)acetic acid HCl; PubChem22177; SCHEMBL6136173; CTK8I9939; DTXSID00200048; AKOS022173232; VZ23243; SC-91922; o-aminomethylphenylacetic acid hydrochloride; 2-(2-(Aminomethyl)Phenyl)Acetic Acid HCl; DB-008091; 2-(Aminomethyl)-benzeneacetate hydrochloride; FT-0640044; 067A922
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| Activity |
IC50 > 5000000 nM
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[5] | |||
| Compound Name |
3-Aminobenzoic acid
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Investigative | Compound Info | ||
| Synonyms |
m-Aminobenzoic acid; Benzoic acid, 3-amino-; m-Carboxyaniline; 3-Carboxyaniline; Benzoic acid, m-amino-; Aniline-3-carboxylic acid; meta-aminobenzoic acid; MFCD00007795; m-Aminobenzoesaeure; UNII-G2X3B3O37U; 3-Aminobenzoesaeure; 3-Amino-Benzoic Acid; MLS000069458; CHEMBL307782; G2X3B3O37U; SMR000059135; 3-Aminobenzoic acid, 98%; 3-Aminobenzoic acid, 99+%; EINECS 202-724-4; NSC 15012; BRN 0471603; M-Amonibenzoate; AI3-04707; 3-Aminobenzoesure; m-aninobenzoic acid; M-Amonibenzoic acid; Benzoic acid, 3-amino-, ion(1-); m-amino benzoic acid; 3-amino benzoic acid; Aniline-3-carboxylate; 3-anilinecarboxylic acid; Opera_ID_150; aminobenzenecarboxylic acid; WLN: ZR CVQ; H-(3)Abz-OH; Oprea1_172994; SCHEMBL27648; 4-14-00-01092 (Beilstein Handbook Reference); KSC201Q0P; MLS001076476; DTXSID3059183; HMS2236H06; HMS3369J18; ZINC388179; ACMC-209794; KS-000000FV; NSC15012; STR00672; ANW-13670; BBL037339; BDBM50226518; NSC-15012; SBB028148; STK301688; AKOS000119015; AS00862; CS-W019987; DB02054; MCULE-8263489676; NCGC00018151-01; NCGC00018151-02; NCGC00018151-03; AK-41177; BR-41177; SC-16197; SY001800; DB-022255; A0268; AM20050192; FT-0615027; ST45061462; M-5857; 122900-EP2292589A1; 122900-EP2295053A1; 147527-EP2281563A1; 147527-EP2292589A1; Q223045; 3-Aminobenzoic acid, Vetec(TM) reagent grade, 98%; Q-200359; F2191-0235
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| Activity |
IC50 > 5000000 nM
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[5] | |||
| Compound Name |
(3-Aminomethyl-phenyl)-acetic acid; hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
[3-(Aminomethyl)phenyl]acetic acid hydrochloride; CHEMBL535643; (3-aminomethyl-phenyl)-acetic acid ; hydrochloride; SCHEMBL3761585; 2-(3-(Aminomethyl)Phenyl)Acetic Acid HCl; 3-aminomethylphenylacetic acid hydrochloride
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| Activity |
IC50 > 5000000 nM
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[5] | |||
| Compound Name |
Anthranilic acid
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Investigative | Compound Info | ||
| Synonyms |
2-aminobenzoic acid; o-aminobenzoic acid; o-Carboxyaniline; 2-Carboxyaniline; vitamin L1; o-Anthranilic acid; Benzoic acid, 2-amino-; 1-Amino-2-carboxybenzene; Benzoic acid, amino-; ortho-Aminobenzoic acid; Benzoic acid, o-amino-; Kyselina anthranilova; Carboxyaniline; 2-amino-Benzoic acid; NCI-C01730; Caswell No. 033G; Kyselina o-aminobenzoova; 2-amino benzoic acid; Kyselina anthranilova [Czech]; Vitamin L; Antranilic Acid; Kyselina o-aminobenzoova [Czech]; NSC 144; UNII-0YS975XI6W; BRN 0471803; AI3-02408; Cupric anthranilate; Bis(anthranilato)copper; 0YS975XI6W; NSC 3937; Bis(o-aminobenzoato)copper; Copper, bis(anthranilato)-; Anthranic acid; MFCD00007712; Copper, bis(2-aminobenzoato)-; NCGC00091175-01; DSSTox_CID_94; o-Aminobenzoic acid copper complex; DSSTox_RID_75363; DSSTox_GSID_20094; 2-azaniumylbenzoate; Ortho-amidobenzoic acid; CCRIS 49; NSC3937; HSDB 1321; EINECS 204-287-5; Anthranate; anthanilic acid; o-Anthranilate; o-amino-Benzoate; 2-amino-Benzoate; o-Aminobenzoesaeure; Ortho-amidobenzoate; Ortho-aminobenzoate; 2-aminobezoic acid; anthranilic acid gr; 2-Aminobenzoesaeure; EINECS 215-310-3; 2-Aminophenylacetate; 2-Carboxyphenylamine; Copper, bis(2-aminobenzoato-N,O)-; zlchem 224; o-amino-Benzoic acid; NSC 173996; alpha-Aminobenzoic acid; 2-anilinecarboxylic acid; H-2-Abz-OH; DEA Code 8530; SCHEMBL675; bmse000067; bmse000917; H-(2)Abz-OH; EC 204-287-5; NCIOpen2_001191; Oprea1_390012; CHEMBL14173; ORTH0-AMINOBENZOIC ACID; NSC144; DTXSID8020094; CTK0H4743; ZINC47985; 1-aminobenzene-2-carboxylic acid; NSC-144; ZLC0032; NSC40929; Tox21_111095; Tox21_200703; BBL025605; BDBM50376751; Benzoic acid, amino- (8CI)(9CI); NSC-40929; SBB007560; STK298716; Anthranilic acid-ring-UL-14C, solid; AKOS002667021; Tox21_111095_1; DB04166; EBD2293238; MCULE-8970106555; NCGC00091175-02; NCGC00091175-03; NCGC00258257-01; AC-11503; Anthranilic acid, reagent grade, >=98%; BP-30147; DS-009700; A0497; ST45061374; T7335; 3296-EP2277869A1; 3296-EP2277870A1; 3296-EP2298743A1; 3296-EP2308848A1; C00108; 74635-EP2269988A2; 74635-EP2270002A1; 74635-EP2270008A1; 74635-EP2270113A1; 74635-EP2272935A1; 74635-EP2292617A1; 74635-EP2295425A1; 74635-EP2305649A1; 74635-EP2308838A1; BENZOIC ACID,2-AMINO ANTHRANILIC ACID; 104650-EP2289894A2; 104650-EP2302132A1; Anthranilic acid, puriss. p.a., >=99.5% (T); Q385140; 3B851741-2A4D-440D-BB22-1A455121BA21
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| Activity |
IC50 > 5000000 nM
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[5] | |||
| Compound Name |
3-(Aminomethyl)-2,6-difluorophenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL321931; 3-Aminomethyl-2,6-difluoro-phenol; SCHEMBL14920108; 2,4-Difluoro-3-hydroxybenzylamine; 2,6-Difluoro-3-(aminomethyl)phenol; ZINC13556339; 3-(azaniumylmethyl)-2,6-difluorophenolate
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| Activity |
Ki = 6300000 nM
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[6] | |||
| Compound Name |
4-(Aminomethyl)-2,6-difluorophenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL112496; SCHEMBL6302839; CTK8H8372; 3,5-Difluoro-4-hydroxybenzylamine; 4-Aminomethyl-2,6-difluoro-phenol; 2,6-Difluoro-4-(aminomethyl)phenol; BDBM50073151; ZINC26832456; AKOS017514987; SC-39972; 4-(ammoniomethyl)-2,6-difluorobenzenolate; 4-(azaniumylmethyl)-2,6-difluorophenolate
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| Activity |
Ki = 11000000 nM
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[6] | |||
| Compound Name |
(1S,2R)-2-Amino-cyclohex-3-enecarboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL138407; (1S,2R)-2-Amino-cyclohex-3-ene carboxylic acid; SCHEMBL579366; (1S,2R/1R,2S)-2-AMINOCYCLOHEX-3-ENE-1-CARBOXYLIC ACID; CTK1A0672; ZINC2526822; BDBM50118887; MFCD08437540; AKOS030212993; TS-7190; (1S,2R)-2-azaniumylcyclohex-3-ene-1-carboxylate; 2alpha-Amino-3-cyclohexene-1alpha-carboxylic acid; 3-Cyclohexene-1-carboxylicacid, 2-amino-, (1S,2R)-; (1S,2R)-2-AMINOCYCLOHEX-3-ENE-1-CARBOXYLIC ACID
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| Activity |
Ki = 13000000 nM
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[2] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis and structure-activity relationships of a series of aminopyridazine derivatives of gamma-aminobutyric acid acting as selective GABA-A antagonists. J Med Chem. 1987 Feb;30(2):239-49. | ||||
| REF 2 | Inactivation and inhibition of gamma-aminobutyric acid aminotransferase by conformationally restricted vigabatrin analogues. J Med Chem. 2002 Sep 26;45(20):4531-9. | ||||
| REF 3 | Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. Bioorg Med Chem Lett. 2006 Feb;16(3):592-5. | ||||
| REF 4 | Flavones: an important scaffold for medicinal chemistry. Eur J Med Chem. 2014 Sep 12;84:206-39. | ||||
| REF 5 | Synthesis and evaluation of novel aromatic substrates and competitive inhibitors of GABA aminotransferase. Bioorg Med Chem Lett. 2008 May 15;18(10):3122-5. | ||||
| REF 6 | Synopsis of some recent tactical application of bioisosteres in drug design. J Med Chem. 2011 Apr 28;54(8):2529-91. | ||||
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