Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T60529 | Target Info | |||
| Target Name | Prostaglandin G/H synthase 1 (COX-1) | ||||
| Synonyms |
Prostaglandin-endoperoxide synthase 1; Prostaglandin H2 synthase 1; PHS 1; PGHS-1; PGH synthase 1; Cyclooxygenase-1; COX1; COX-1
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| Target Type | Successful Target | ||||
| Gene Name | PTGS1 | ||||
| Biochemical Class | Paired donor oxygen oxidoreductase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 970 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Carprofen
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Approved | Compound Info | ||
| Synonyms |
Carprofene; Carprofeno; Carprofenum; Imadyl; Ridamyl; Rimadyl; Carprofeno [Spanish]; C 5720; Ro 205720; C-5720; Carprofene [INN-French]; Carprofeno [INN-Spanish]; Carprofenum [INN-Latin]; Rimadyl (TN); Ro 20-5720; Carprofen (USAN/INN); Carprofen [USAN:INN:BAN]; Ro 20-5720/000; Ro-20-5720; Ro-20-5720/000; (+-)-6-Chloro-alpha-methylcarbazole-2-acetic acid; (+-)-isomer of carprofen; (+/-)-2-(3-chloro-9H-carbazol-7-yl)propanoic acid; (+/-)-6-Chloro-.alpha.-methylcarbazole-2-acetic acid; (-)-6-Chlor-alpha-methyl-2-carbazolessigsaeure; 2-(6-Chloro-9H-carbazol-2-yl)-propionic acid; 2-(6-Chloro-9H-carbazol-2-yl)propanoic acid; 6-Chlor-alpha-methyl-carbazol-2-essigsaeure; 6-Chlor-alpha-methyl-carbazol-2-essigsaeure [German]; 6-Chloro-alpha-methyl-9H-carbazole-2-acetic acid; 6-Chloro-alpha-methylcarbazole-2-acetic acid; 9H-Carbazole-2-acetic acid, 6-chloro-.al
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| Activity |
IC50 = 59000 nM
|
[1] | |||
| Compound Name |
Rofecoxib
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Approved | Compound Info | ||
| Synonyms |
Ceoxx; Refecoxib; Vioxx; Cahill May Roberts brand of rofecoxib; MSD brand of rofecoxib; Merck Frosst brandof rofecoxib; Merck brand of rofecoxib; Vioxx Dolor; MK 0966; MK 0996; MK 966; MK0966; Ceeoxx (TN); Ceoxx (TN); KS-1107; MK-0966; MK-966; Merck Sharp & Dhome brand of rofecoxib; Vioxx (TN); Vioxx (trademark); Rofecoxib (JAN/USAN/INN); 3-(4-methylsulfonylphenyl)-4-phenyl-2H-furan-5-one; 3-Phenyl-4-(4-(methylsulfonyl)phenyl))-2(5H)-furanone; 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone; 4-(4-(Methylsulfonyl)phenyl)-3-phenyl-2(5H)-furanone; 4-(4-methylsulfonylphenyl)-3-phenyl-5H-furan-2-one; 4-(p-(Methylsulfonyl)phenyl)-3-phenyl-2(5H)-furanone; 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone; 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one
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| Activity |
IC50 = 62000 nM
|
[2] | |||
| Compound Name |
Aspirin
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Approved | Compound Info | ||
| Synonyms |
ACETYLSALICYLIC ACID; 50-78-2; 2-Acetoxybenzoic acid; o-Acetoxybenzoic acid; O-Acetylsalicylic acid; Polopiryna; Acylpyrin; Ecotrin; Easprin; Acetylsalicylate; Acetophen; Acenterine; Acetosal; Colfarit; Salicylic acid acetate; o-Carboxyphenyl acetate; Enterosarein; Aspergum; Salcetogen; Pharmacin; Acetosalin; Premaspin; Micristin; Benaspir; Aspirdrops; Acetonyl; Aceticyl; Temperal; Acetylin; Empirin; Ecolen; Rhodine; Endydol; Saletin; Rheumintabletten; Solprin acid; Acidum acetylsalicylicum; Globentyl; Pravigard
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| Activity |
Ki = 62000 nM
|
[3] | |||
| Compound Name |
Etoricoxib
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Approved | Compound Info | ||
| Synonyms |
Algix; Arcoxia; Etoricoxibe; Nucoxia; Tauxib; L791456; MK 0663; MK 663; Algix (TN); Arcoxia (TN); L-791456; MK-0663; MK-663; Merck Sharp & Dohme brand of etoricoxib; Tauxib (TN); Etoricoxib (USAN/INN); Etoricoxib [USAN:INN:BAN]; 5-Chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine; 5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine; 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine; 5CH
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| Activity |
IC50 = 98800 nM
|
[4] | |||
| Compound Name |
Valdecoxib
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Approved | Compound Info | ||
| Synonyms |
Bextra; COX; Kudeq; Valdyn; Pfizer brand of valdecoxib; Valdecoxib [USAN]; SC 65872; ND-0214; SC-65872; YM-974; Valdecoxib (USAN/INN); P-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide; Benzenesulfonamide, 4-(5-methyl-3-phenyl-4-isoxazolyl)-(9CI); 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide; 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide; 4-(5-methyl-3-phenyl-4-isoxazolyl) benzenesulfonamide; 4-(5-methyl-3-phenyl-isoxazol-4-yl)benzenesulfonamide; 4-(5-methyl-3-phenylisoxazol-4-yl)benzenesulfonamide; 4-(Methyl-3-phenyl-isoxazol-4-yl)-benzenesulfonamide
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
Acetaminophen
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Approved | Compound Info | ||
| Synonyms |
acetaminophen; 4-Acetamidophenol; Paracetamol; 103-90-2; Tylenol; N-(4-Hydroxyphenyl)acetamide; APAP; Acetaminofen; Panadol; Datril; p-Hydroxyacetanilide; N-Acetyl-p-aminophenol; p-Acetamidophenol; Algotropyl; Naprinol; Lonarid; 4'-Hydroxyacetanilide; Multin; Acenol; Acamol; Anelix; p-Acetaminophenol; Liquagesic; Acetagesic; Gelocatil; Servigesic; Acetalgin; Abensanil; Pyrinazine; Injectapap; Clixodyne; Valgesic; Tussapap; Finimal; Paracet; Homoolan; Febrolin; Febrilix; Febridol; Dymadon; Anaflon; Apamide; Valadol; Tralgon; Tabalgin; Lestemp; Alvedon; Abenol; Abrol; Abrolet; Acephen; Acertol; Acetaco; Acetamol; Acetavance; Acetofen; Actamin; Actimol; Afebrin; Afebryl; Aferadol; Algesidal; Algina; Algomol; Alpiny; Alpinyl; Amadil; Aminofen; Analter; Anapap; Andox; Anhiba; Antidol; Anuphen; Apacet; Apadon; Apitrelal; Arfen; Arthralgen; Asetam; Asomal; Aspac; Asplin; Atasol; Atralidon; Babikan; Bacetamol; Banesin; Benmyo; Biocetamol; Cadafen; Calapol; Calmanticold; Calonal; Calpol; Capital; Captin; Causalon; Cefalex; Cetadol; Codabrol; Codalgin; Codapane; Codicet; Codisal; Codoliprane; Cofamol; Conacetol; Cosutone; Cuponol; Curadon; Curpol; Custodial; Dafalgan; Darocet; Darvocet; Daygrip; Deminofen; Democyl; Demogripal; Desfebre; Dhamol; Dimindol; Dirox; Disprol; Dolcor; Dolefin; Dolegrippin; Dolgesic; Doliprane; Dolko; Dolofugin; Doloreduct; Dolorfug; Dolorstop; Dolotec; Dolprone; Dorocoff; Dresan; Dristancito; Duaneo; Dularin; Duorol; Duracetamol; Durapan; Dypap; Ecosetol; Elixodyne; Empracet; Enelfa; Eneril; Excipain; Exdol; Fanalgic; Farmadol; Febranine; Febrectal; Febrectol; Febrex; Febricet; Febrin; Febrinol; Fendon; Fensum; Fepanil; Fevor; Finiweh; Fluparmol; Geluprane; Genapap; Genebs; Grippostad; Gynospasmine; Hedex; Ildamol; Inalgex; Infadrops; Janupap; Kataprin; Korum; Labamol; Lekadol; Lemgrip; Lemsip; Liqiprine; Lupocet; Lyteca; Magnidol; Malgis; Malidens; Maxadol; Medocodene; Mexalen; Minafen; Minoset; Miralgin; Momentum; NEBS; Napafen; Nealgyl; NeoCitran; Neodol; Neodolito; Neopap; Neotrend; Neuridon; NilnOcen; Nina; Nobedon; Nodolex; Noral; Ofirmev; Oltyl; Oralgan; Ortensan; Oxycocet; Paceco; Pacemo; Pacemol; Pacet; Pacimol; Paedialgon; Paedol; Painex; Paldesic; Pamol; Panacete; Panadeine; Panadiene; Panaleve; Panamax; Panasorb; Panasorbe; Panets; Panex; Panodil; Panofen; Pantalgin; Paracemol; Paracenol; Paracetamole; Paracetamolo; Paracetanol; Paracetol; Paracin; Paracod; Paracodol; Parador; Paradrops; Parakapton; Parake; Paralen; Paralief; Paralink; Paralyoc; Paramol; Paramolan; Paranox; Parapan; Parasedol; Parasin; Paraspen; Parcetol; Parelan; Parmol; Parogal; Paroma; Pasolind; Pediapirin; Pediatrix; Pedric; Perfalgan; Phendon; Phenipirin; Phogoglandin; Pinex; Piramin; Pirinasol; Plicet; Polmofen; Predimol; Predualito; Prodol; Prompt; Prontina; Puernol; Pulmofen; Pyrigesic; Pyromed; Redutemp; Reliv; Remedol; Rivalgyl; Robigesic; Rounox; RubieMol; Rubophen; Rupemol; Salzone; Sanicet; Sanicopyrine; Scanol; Scentalgyl; Schmerzex; Sedalito; Semolacin; Seskamol; Setakop; Setamol; Setol; Sifenol; Sinaspril; Sinedol; Sinmol; Stanback; Stopain; Sunetheton; Supofen; Suppap; TYL; Tachiprina; Tapanol; Tapar; Tazamol; Temlo; Tempanal; Tempra; Termacet; Termalgin; Termalgine; Termofren; Tiffy; Titralgan; Treuphadol; Tricoton; Tylex; Tylol; Tymol; Upsanol; Utragin; Valorin; Veralgina; Vermidon; Verpol; Vips; Viruflu; Vivimed; Volpan; Zatinol; Zolben; Aceta Elixir; Actifed Plus; Aspirin free anacin; Bayer Select; D oliprane; Dymadon Co; Fortalidon P; Gattaphen T; Gripin Bebe; Helon N; Influbene N; Jin Gang; Lonarid Mono; Lyteca Syrup; Malex N; Panadeine Co; Panale ve; Pasolind N; Spalt N; Supadol mono; Toximer P; Treupel N; Treupel mon; Ty lenol; Tylex CD; Anacin 3; A-Per; Accu-Tap; Ultracet
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| Activity |
IC50 = 200000 nM
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[6] | |||
| Compound Name |
Genistein
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Phase 2/3 | Compound Info | ||
| Synonyms |
Bonistein; GEN; Genestein; Genisteol; Genisterin; Prunetol; Sophoricol; Differenol A; G 6649; G10000; IN1327; NPI 031L; STO514; TNP00151; GENISTEIN (ENDOCRINE DISRUPTER); Lactoferrin-genistein; PTI G4660 (Genistein); PTI-G4660; SIPI 807-1; C.I. 75610; SIPI-9764-I; ENDOCRINE DISRUPTOR (GENISTEIN) (SEE ALSO GENISTEIN (446-72-0)); 4 inverted exclamation marka,5,7-Trihydroxyisoflavone; ,5,7-Trihydroxyisoflavone; 4',5, 7-Trihydroxyisoflavone; 4',5,7-Trihydroxy isoflavone; 4',5,7-Trihydroxyisoflavone; 4,5,7-Trihydroxyiso-flavone; 4,6,7-Trihydroxyisoflavone; 5,7,4'-Trihydroxyisoflavone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one; 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
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| Activity |
IC50 = 80000 nM
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[7] | |||
| Compound Name |
ORG-13011
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Phase 2 | Compound Info | ||
| Synonyms |
FIBOFLAPON; 936350-00-4; UNII-Y1NA96IX3T; Y1NA96IX3T; CHEMBL1922660; Fiboflapon [USAN:INN]; AM803; Fiboflapon (USAN); AM-803; AM 803; SCHEMBL11820; DTXSID20239496; DFQGDHBGRSTTHX-UHFFFAOYSA-N; GSK2190915B; ZINC68247071; BDBM50359080; AKOS030527019; SB16524; CS-3604; Fiboflapon; NCGC00485966-01; HY-15874; 1H-Indole-2-propanoic acid, 3-((1,1-dimethylethyl)thio)-1-((4-(6-ethoxy-3-pyridinyl)phenyl)methyl)-alpha,alpha-Dimethyl-5-((5-methyl-2-pyridinyl)methoxy)-; D10069
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| Activity |
IC50 = 58000 nM
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[8] | |||
| Compound Name |
4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-hydroxy-benzenesulfonamide
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Phase 1/2 | Compound Info | ||
| Synonyms |
CHEMBL35685; BDBM50111002
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| Activity |
IC50 ~ 100000 nM
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[9] | |||
| Compound Name |
Indomethacin analog 3
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Patented | Compound Info | ||
| Synonyms |
PMID28895472-Compound-22
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| Activity |
IC50 ~ 100000 nM
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[10] | |||
| Compound Name |
PMID26394986-Compound-22
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Patented | Compound Info | ||
| Activity |
IC50 = 100000 nM
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[11] | |||
| Compound Name |
N-(naphthylamino)-benzoate derivative 1
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Patented | Compound Info | ||
| Synonyms |
PMID28895472-Compound-28
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| Activity |
IC50 ~ 100000 nM
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[12] | |||
| Compound Name |
US9388139, 12
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Patented | Compound Info | ||
| Synonyms |
SCHEMBL12493454; CHEMBL3899621; BDBM236643; US9388139, 12
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| Activity |
IC50 ~ 100000 nM
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[13] | |||
| Compound Name |
Nimesulide
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Withdrawn from market | Compound Info | ||
| Synonyms |
nimesulide; 51803-78-2; N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide; Mesulid; Flogovital; Sulidene; Nimed; R-805; 4-NITRO-2-PHENOXYMETHANESULFONANILIDE; Nisulid; Nimesulidum [INN-Latin]; Nimesulida [INN-Spanish]; R 805; UNII-V4TKW1454M; 4-Nitro-2-phenoxy-methanesulfonanilide; 4'-Nitro-2'-phenoxymethanesulfonanilide; Methanesulfonamide, N-(4-nitro-2-phenoxyphenyl)-; EINECS 257-431-4; 4'-Nitro-2'-phenoxymethansulfonanilid; BRN 2421175; CHEMBL56367; MLS000069680; V4TKW1454M; Methanesulfonanilide, 4'-nitro-2'-phenoxy-; CHEBI:44445; Dulanermin
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| Activity |
IC50 = 50000 nM
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[14] | |||
| Compound Name |
GW-406381
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Discontinued in Phase 3 | Compound Info | ||
| Synonyms |
GW 406381; GW406381; 8-(4-ethoxyphenyl)-7-(4-methylsulfonylphenyl)-1,2,9-triazabicyclo[4.3.0]nona-2,4,6,8-tetraene
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| Activity |
IC50 ~ 84200 nM
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[15] | |||
| Compound Name |
ZD-2138
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Discontinued in Phase 2 | Compound Info | ||
| Synonyms |
Ici D2138; 140841-32-3; ZD-2138; UNII-B6G6OX1ZH5; B6G6OX1ZH5; CHEMBL20403; 2(1H)-Quinolinone,6-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-methyl-; Ici-D2138; 6-((3-fluoro-5-(4-methoxytetrahydro-2H-pyran-4-yl)phenoxy)methyl)-1-methylquinolin-2(1H)-one; ZD 2138; ACMC-20mzth; AC1L30RD; zd2138; 6-((3-Fluoro-5-(4-methoxy-3,4,5,6-tetrahydro-2H-pyran-4-yl)phenoxy)methyl)-1-methylquinol-2-one; SCHEMBL1083603; CTK4C2357; DTXSID90161477; BDBM50000829; AKOS025404954; ACN-048395
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| Activity |
IC50 ~ 100000 nM
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[16] | |||
| Compound Name |
Tilmacoxib
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Discontinued in Phase 2 | Compound Info | ||
| Synonyms |
Tilmacoxib; JTE-522; 180200-68-4; RWJ-57504; JTP-19605; UNII-G6VI5P84SX; 4-(4-Cyclohexyl-2-methyloxazol-5-yl)-2-fluorobenzenesulfonamide; Benzenesulfonamide, 4-(4-cyclohexyl-2-methyl-5-oxazolyl)-2-fluoro-; G6VI5P84SX; CHEMBL34913; JTE522; 5-ethoxymethyl-7-fluoro-3-oxo-1,2,3,5-tetrahydrobenzo(4,5)imidazo(1,2a)pyridine-4-N-(2-fluorophenyl)carboxamide; CHEBI:73041; 4-(4-cyclohexyl-2-methyl-1,3-oxazol-5-yl)-2-fluorobenzenesulfonamide; 4-(4-cyclohexyl-2-methyl-5-oxazolyl)-2-fluorobenzenesulfonamide
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| Activity |
IC50 ~ 100000 nM
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[9] | |||
| Compound Name |
SC-57666
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Discontinued in Phase 1 | Compound Info | ||
| Synonyms |
SC-57666; CHEMBL274893; AC1L9EJK; SC57666; CHEBI:8982; 1-fluoro-4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzene; SureCN213008; SCHEMBL213008; ZINC18527; GJGZQTGPOKPFES-UHFFFAOYSA-N; HY-U00129; BDBM50029614; DNC003789; CS-7166; C11706; 1-[2(4-Flurophenyl)-1-cyclopentyl]4-methylsulfonylbenzene; 1-[2-(4-fluorophenyl)cyclopenten-1-yl]-4-(methylsulfonyl)benzene; 1-[2-(4-fluorophenyl) cyclopenten-1-yl]-4- (methylsulfonyl)benzene; 1-fluoro-4-[2-(4-methylsulfonylphenyl)-1-cyclopentenyl]benzene
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| Activity |
IC50 ~ 50000 nM
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[17] | |||
| Compound Name |
L-745337
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Terminated | Compound Info | ||
| Synonyms |
Thioflosulide; L-745337; CHEMBL287919; 158205-05-1; L 745337; L 745,337; L-745,337; SCHEMBL2464202; ZINC1887701; BDBM50029603; CS-6783; N-(6-((2,4-Difluorophenyl)thio)-2,3-dihydro-1-oxo-1H-inden-5-yl)methanesulfonamide; HY-19217; L745,337
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| Activity |
IC50 ~ 50000 nM
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[18] | |||
| Compound Name |
Flosulide
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Terminated | Compound Info | ||
| Synonyms |
CGP-28238; CGP-28328; CGS-28238; SH-459; ZK-38997
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| Activity |
IC50 ~ 50000 nM
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[18] | |||
| Compound Name |
SC-58125
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Terminated | Compound Info | ||
| Synonyms |
SC-58125; 162054-19-5; SC 58125; C17H12F4N2O2S; 1-((4-Methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole; CHEBI:8983; CHEMBL274990; 5-(4-fluorophenyl)-1-(4-methylsulfonylphenyl)-3-(trifluoromethyl)pyrazole; 1-[(4-METHYLSULFONYL)PHENYL]-3-TRIFLUOROMETHYL-5-(4-FLUOROPHENYL)PYRAZOLE; 5-(4-Fluorophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-1H-pyrazole; 5-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)pyrazole; 1H-Pyrazole, 5-(4-fluorophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(tr
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| Activity |
IC50 ~ 50000 nM
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[17] | |||
| Compound Name |
NS398
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Terminated | Compound Info | ||
| Synonyms |
ns-398; 123653-11-2; NS398; NS 398; N-(2-Cyclohexyloxy-4-nitrophenyl)methanesulfonamide; N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide; CHEMBL7162; CHEBI:73458; Methanesulfonamide, N-(2-(cyclohexyloxy)-4-nitrophenyl)-; n-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide; N-(2-Cyclohexyloxy-4-nitro-phenyl)-methanesulfonamide; Taisho NS 398; SR-01000597479; N-[2-Cyclohexyloxy-4-nitrophenyl]methanesulfonamide; N-(2-(cyclohexyloxy)-4-nitrophenyl)methanesulfonamide; CCRIS 8523; KTDZCOWXCWUPEO-UHFFFAOYSA-N; Tocris-0942
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| Activity |
IC50 ~ 100000 nM
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[19] | |||
| Compound Name |
esculetin
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Investigative | Compound Info | ||
| Synonyms |
aesculetin; 6,7-dihydroxycoumarin; cichorigenin
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| Activity |
IC50 = 57000 nM
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[7] | |||
| Compound Name |
Caffeic acid phenethyl ester
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Investigative | Compound Info | ||
| Synonyms |
Caffeic acid phenethyl ester; Phenethyl caffeate; 104594-70-9; CAPE; phenethyl 3-(3,4-dihydroxyphenyl)acrylate; Capeee; Phenylethyl caffeate; 115610-29-2; caffeic acid phenylethyl ester; UNII-G960R9S5SK; 2-phenylethyl caffeate; PHENETHYL CAFFEATE (CAPE); Caffeic acid-phenethyl ester; CHEBI:8062; G960R9S5SK; CHEMBL319244; 100981-80-4; Caffeic acid 2-phenylethyl ester; SWUARLUWKZWEBQ-VQHVLOKHSA-N; 2-phenylethyl 3-(3,4-dihydroxyphenyl)-2-propenoate; Caffeic Acid Phenethyl Ester, Synthetic; 2-Phenylethyl (2e)-3-(3,4-Dihydroxyphenyl
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| Activity |
IC50 = 58000 nM
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[7] | |||
| Compound Name |
GW-637185X
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL539663; GW-637185X; GW637185X; BDBM50297670
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| Activity |
IC50 = 62000 nM
|
[5] | |||
| Compound Name |
4-(4-methyl-phenyliminomethyl)-benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL271962; SCHEMBL5309671; GFCNORPCMFOXDQ-UHFFFAOYSA-N; BDBM50371756
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| Activity |
IC50 = 63220 nM
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[20] | |||
| Compound Name |
4-phenyliminomethyl-benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
4-phenyliminomethyl-benzenesulfonamide; CHEMBL407019; SCHEMBL5311443
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| Activity |
IC50 = 63590 nM
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[20] | |||
| Compound Name |
LM-4108
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Investigative | Compound Info | ||
| Synonyms |
N-(2-Phenylethyl)indomethacin Amide; 261766-32-9; CHEMBL95311; N-(2-Phenylethyl)indomethacinamide; C27H25ClN2O3; 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)-N-phenethylacetamide; 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}-N-(2-phenylethyl)acetamide; LM-4108; 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indol-3-yl]-n-phenethylacetamide; LM 4108; AC1L1HU5; Indomethacin derivative, 19; SCHEMBL678111; BDBM22966; CTK8E8937; DTXSID80274424; MolPort-001-581-215; HMS3649K21; ZINC602343; STK226516
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 66000 nM
|
[21] | |||
| Compound Name |
4-(4-fluoro-phenyliminomethyl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL272622; SCHEMBL5312313; JAKLWQFGJXPTHN-UHFFFAOYSA-N; BDBM50371742
Click to Show/Hide
|
||||
| Activity |
IC50 = 80200 nM
|
[20] | |||
| Compound Name |
Firocoxib
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Firocoxib; 189954-96-9; Equioxx; Previcox; Equixx; Librens; UNII-Y6V2W4S4WT; Y6V2W4S4WT; CHEMBL69998; CHEBI:76136; 3-(CYCLOPROPYLMETHOXY)-5,5-DIMETHYL-4-[4-(METHYLSULFONYL)PHENYL]-2(5H)-FURANONE; ML 1785713; 3-(cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one; 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one; Firocoxib [USAN:INN]; firocoxibum; 3-(cyclopropylmethoxy)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-one; Firocoxib (USAN/INN); AC1L4LLA; ML-1,785,713
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
AM-643
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
FLAP inhibitor (topical, dermatological disorder), Amira; 5-lipoxygenase-activating protein inhibitor (topical, dermatological disorder), Amira
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[23] | |||
| Compound Name |
4-((4-hydroxyphenyl)diazenyl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-(4'-Hydroxyphenyl)diazenylbenzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
3,4-dihydroxyxanthone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3,4-Dihydroxyxanthone; 3,4-Dihydroxy-xanthone; 3,4-dihydroxyxanthen-9-one; CHEMBL446323; 39731-48-1; AC1NX8OR; SCHEMBL133422; 3,4-dihydroxy-xanthen-9-one; CTK4I1796; DTXSID20192815; YFVCSEXMOBEPQB-UHFFFAOYSA-N; 3,4-dihydroxy-9H-xanthen-9-one; 9H-Xanthen-9-one,3,4-dihydroxy-; ZINC15119047; BDBM50269645; 9H-Xanthen-9-one, 3,4-dihydroxy-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
KAEMPFEROL
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
kaempferol; 520-18-3; Kaempherol; Kempferol; Trifolitin; Populnetin; Robigenin; Rhamnolutein; Pelargidenolon; Rhamnolutin; Swartziol; Indigo Yellow; Kampherol; Nimbecetin; Kampferol; Campherol; Kaemferol; 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; 5,7,4'-Trihydroxyflavonol; Pelargidenolon 1497; 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; C.I. 75640; CCRIS 41; NSC 407289; 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one; 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphe
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[26] | |||
| Compound Name |
2,6-dihydroxy-1,7-dimethoxyxanthone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
calophymembranol A; 2,6-dihydroxy-1,7-dimethoxyxanthone; CHEMBL463769; AC1NRZXJ; BDBM50269644; 2,6-dihydroxy-1,7-dimethoxyxanthen-9-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[25] | |||
| Compound Name |
4-((4-methoxyphenyl)diazenyl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL213267; 4-((4-methoxyphenyl)diazenyl)benzenesulfonamide; 4-[(4-methoxyphenyl)diazenyl]benzenesulfonamide; NSC722840; AC1L8P6K; CTK7A1570; MolPort-002-934-354; ZINC6484196; STK037234; BDBM50190339; AKOS005382697; NSC-722840; MCULE-3486440340; 4-(4-Methoxy-phenylazo)-benzenesulfonamide; 4-[(E)-(4-methoxyphenyl)diazenyl]benzenesulfonamide; benzenesulfonamide, 4-[(e)-2-(4-methoxyphenyl)diazenyl]-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
4-(3-nitro-benzylideneamino)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL404921; BDBM50371766; AKOS003620777
Click to Show/Hide
|
||||
| Activity |
IC50 = 105630 nM
|
[20] | |||
| Compound Name |
4-(benzylideneamino)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
4-benzylideneamino-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 108340 nM
|
[20] | |||
| Compound Name |
gingerol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
[6]-Gingerol; 6-Gingerol
Click to Show/Hide
|
||||
| Activity |
IC50 = 129000 nM
|
[27] | |||
| Compound Name |
4-(4-nitro-benzylideneamino)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL255175; 66667-60-5; 4-[(1E)-2-(4-nitrophenyl)-1-azavinyl]benzenesulfonamide; AC1LBU0E; 4-[(4-nitrophenyl)methylideneamino]benzenesulfonamide; SCHEMBL12416808; CTK5I3043; CTK1J4461; DTXSID10340363; IJEQJCKQAKELNC-OQLLNIDSSA-N; MolPort-001-818-097; ZINC131032; BDBM50371746; STK790732; SBB006116; AKOS001719928; MCULE-1611993564; MCULE-9098092341; ST016439; EU-0084260; 4-(4-Nitrobenzylideneamino)Benzenesulfonamide; 4-[(4-Nitrobenzylidene)amino]benzenesulfonamide; Benzenesulfonamide, 4-(4-nitrobenzylidenamino)-
Click to Show/Hide
|
||||
| Activity |
IC50 = 141250 nM
|
[20] | |||
| Compound Name |
4-(4-fluoro-benzylideneamino)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL427835; 4-[(4-fluorobenzylidene)amino]benzenesulfonamide; 4-{[(e)-(4-fluorophenyl)methylidene]amino}benzenesulfonamide; NSC720519; AC1L8N2R; SCHEMBL5311683; CTK7B9640; BKZPDMSMFWCHPI-UHFFFAOYSA-N; MolPort-003-705-944; ZINC18102137; BDBM50371768; ZINC95919526; AKOS001613042; ZINC253618202; AKOS016038195; NSC-720519; MCULE-4378033729; ST009698; KB-117288; N-(4-Fluorobenzylidene)-4-sulfamoylaniline; EU-0002043; SR-01000079257; SR-01000079257-1; 4-[(4-Fluoro-benzylidene)-amino]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 159070 nM
|
[20] | |||
| Compound Name |
4-(4-methyl-benzylideneamino)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL429915; AC1LEQSK; SCHEMBL5312741; SOHFVFXITPDEDK-UHFFFAOYSA-N; ZINC95919525; ZINC18036434; BDBM50371763; ZINC253618240; AKOS016038193; AKOS003632590; MCULE-3900521489; ST009696; N-(4-Methylbenzylidene)-4-sulfamoylaniline; J3.552.121F; 4-[[(E)-4-Methylbenzylidene]amino]benzenesulfonamide; 4-[(4-methylphenyl)methylideneamino]benzenesulfonamide; 4-[(1E)-2-(4-methylphenyl)-1-azavinyl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 190470 nM
|
[20] | |||
| Compound Name |
6-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-imidazo[2,1-b]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148976; SCHEMBL3247762; BDBM50289298; 6-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)imidazo[2,1-b][1,3]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
(E)-N-Butyl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334141; BDBM50429262
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
Chembl4173747
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL20897022; BDBM50283372
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[30] | |||
| Compound Name |
6-(3,4-Difluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-imidazo[2,1-b]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL423576; BDBM50289297
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
2-[3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-yl]-propan-2-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL367778; BDBM50286953
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
(E)-N-Butan-2-yl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333748; BDBM50429279
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
N-(4-Bromophenylsulfonyl)Picolinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1916964; BDBM50357955
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[31] | |||
| Compound Name |
2-Bromo-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-thiophene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL97935; BDBM50286049
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
N-[6-(2-Fluoro-phenylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL144819; BDBM50048200; N-[6-[(2-Fluorophenyl)thio]-1-oxoindan-5-yl]methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
4-(4-Methanesulfonyl-phenyl)-5,5-dimethyl-3-phenylsulfanyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL324670; SCHEMBL5204904; BDBM50082350; 5,5-dimethyl-4-(4-methylsulfonylphenyl)-3-phenylsulfanylfuran-2-one; 3-(Phenylthio)-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[32] | |||
| Compound Name |
6-(4-Methanesulfonyl-phenyl)-3-methyl-5-phenyl-imidazo[2,1-b]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL149167; BDBM50289301
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
5-(4-Methanesulfonyl-phenyl)-2,3-dimethyl-6-phenyl-imidazo[2,1-b]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL358482; SCHEMBL3252364; BDBM50289313; 2,3-dimethyl-5-(4-methylsulfonylphenyl)-6-phenylimidazo[2,1-b][1,3]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
Clematichinenoside C
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1171452; BDBM50322745; C17806
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
5-(4-Methanesulfonyl-phenyl)-6-phenyl-imidazo[2,1-b]thiazole-3-carboxylic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL149936; BDBM50289307
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
2-[4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-thiophen-2-yl]-propan-2-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL367885; BDBM50286943
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-(2-ethylpiperidin-1-yl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333734; BDBM50429272
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-dihexylprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334133; BDBM50429289
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
5-(4-Methanesulfonyl-phenyl)-2-methyl-6-phenyl-imidazo[2,1-b]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL358609; SCHEMBL3247750; BDBM50289302; 2-methyl-5-(4-methylsulfonylphenyl)-6-phenylimidazo[2,1-b][1,3]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-thiazolo[3,2-b][1,2,4]triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL348104; BDBM50289315
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[34] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-(2-methylpropyl)prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333747; BDBM50429280
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
2-Phenyl-3-[4-(methylsulfonyl)phenyl]imidazo[2,1-b]benzothiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL424313; BDBM50289308; 3-(4-Methanesulfonyl-phenyl)-2-phenyl-benzo[d]imidazo[2,1-b]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] (4aS,6aR,6aS,6bR,8aR,9R,10S,12aR,14bS)-10-[(2S,3R,4S,5S)-3-[(2S,3R,4R,5S,6S)-4-[(2S,3R,4S,5R)-5-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxyoxan-2-yl]oxy-3,5-dihydroxy-6-methyloxan-2-yl]oxy-4,5-dihydroxyoxan-2-yl]oxy-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1171455; BDBM50322765
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
N-[4-(3,4-Dichlorophenyl)phenyl]-4-hydroxy-1,1-dioxo-3,4-dihydro-2H-1lambda6,2-benzothiazine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1080552; BDBM50313219
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[35] | |||
| Compound Name |
2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-bicyclo[2.2.1]hept-2-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL355771; BDBM50286944
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
N-(4-Methylphenyl)sulfonylpyridine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1916951; 3-Pyridinecarboxamide, N-[(4-methylphenyl)sulfonyl]-; N-Tosylnicotinamide; ACMC-20mif6; Oprea1_807454; CTK0C9363; DTXSID50363531; ZINC1418748; BDBM50357963; STL439090; AKOS000734297; MCULE-3150935145; N-[(4-methylphenyl)sulfonyl]pyridine-3-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[31] | |||
| Compound Name |
N-(6-Cyclohexylsulfanyl-1-oxo-indan-5-yl)-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL144787; BDBM50048223; ZINC13744786
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
3-(4-Ethanesulfonyl-phenyl)-2-(4-fluoro-phenyl)-thiophene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL416687; BDBM50285205
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[36] | |||
| Compound Name |
(E)-N,N-Dibutyl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334130; BDBM50429292
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
4-(4-Methanesulfonyl-phenyl)-5-phenyl-1H-[1,2,3]triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL173961; BDBM50286945
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
4-(4-Fluoro-phenyl)-5-(4-sulfamoyl-phenyl)-thiophene-2-carboxylic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL307983; BDBM50285214
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[36] | |||
| Compound Name |
3-Benzoyl-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL325370; SCHEMBL5208816; BDBM50082347; 3-Benzoyl-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one; 3-Benzoyl-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[32] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-pyrrolidin-1-ylprop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333740; BDBM50429266
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
Huzhangoside B
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1171450; Huzhongoside B; 9563AF; BDBM50322748; C64H104O30; C17807
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-(2-methylpiperidin-1-yl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334136; BDBM50429276
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
2-Chloro-6-(4-chloro-phenyl)-5-(4-methanesulfonyl-phenyl)-imidazo[2,1-b]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148708; SCHEMBL3246624; BDBM50289299; 2-chloro-6-(4-chlorophenyl)-5-(4-methylsulfonylphenyl)imidazo[2,1-b][1,3]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
5-(4-Methanesulfonyl-phenyl)-6-(3-methoxy-phenyl)-thiazolo[3,2-b][1,2,4]triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL347378; BDBM50289320
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[34] | |||
| Compound Name |
N-(4-Fluorophenylsulfonyl)Nicotinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1916948; BDBM50357973
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[31] | |||
| Compound Name |
N-(1-Oxo-6-o-tolylsulfanyl-indan-5-yl)-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL144675; BDBM50048214; N-[6-[(2-Methylphenyl)thio]-1-oxoindan-5-yl]methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
Imidazo[2,1-b]thiazole,5-[4-(methylsulfonyl)phenyl]-6-phenyl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL146742; L-766112; SCHEMBL3246464; ZINC601816; BDBM50289303; 5-(4-(methylsulfonyl)phenyl)-6-phenylimidazo[2,1-b]thiazole; 5-(4-Methanesulfonyl-phenyl)-6-phenyl-imidazo[2,1-b]thiazole; 5-(4-methylsulfonylphenyl)-6-phenylimidazo[2,1-b][1,3]thiazole; 5-(4-Methanesulfonyl-phenyl)-6-phenyl-3,5-dihydro-1lambda*4*-imidazo[2,1-b]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[2,3-c][1,2,4]triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL346288; BDBM50289318
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[34] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-(4-methylpiperidin-1-yl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334138; BDBM50429274
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-piperidin-1-ylprop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334135; BDBM50429287
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
(E)-N-Cyclohexyl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333750; BDBM50429277
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
3-(4-Fluorophenyl)-2-[4-(methanesulfonyl)phenyl]thiophene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL66445; SCHEMBL9259229; CTK3B6963; DTXSID10596747; BDBM50285219; 3-(4-fluorophenyl)-2-(4-methylsulfonylphenyl)thiophene; 3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-thiophene; Thiophene, 3-(4-fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[36] | |||
| Compound Name |
2,3-Dichloro-6-(4-chloro-phenyl)-5-(4-methanesulfonyl-phenyl)-imidazo[2,1-b]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL149597; SCHEMBL5616866; BDBM50289306
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
[4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-thiophen-2-yl]-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL174009; BDBM50286949
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
Chembl4245581
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50463082
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[37] | |||
| Compound Name |
2-(4-Methanesulfonyl-phenyl)-3-phenyl-benzo[d]imidazo[2,1-b]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL356206; BDBM50289309
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
N-[6-(4-Fluoro-phenylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL356940; BDBM50048198; N-[6-[(4-Fluorophenyl)thio]-1-oxoindan-5-yl]methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
5-(4-Methanesulfonyl-phenyl)-6-phenyl-imidazo[2,1-b]thiazole-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL345333; BDBM50289311
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
6-(4-Methanesulfonyl-phenyl)-2,3-dimethyl-5-phenyl-imidazo[2,1-b]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL358666; BDBM50289310
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
3-(3-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL52285; SCHEMBL3246332; BDBM50078686; 4-(3-fluorophenyl)-3-(4-methylsulfonylphenyl)-2H-furan-5-one; 3-(3-Fluorophenyl)-4-[4-(methylsulfonyl)phenyl]-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[38] | |||
| Compound Name |
Ciwujianoside C3
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1171250; HY-N4134; BDBM50322751; CS-0032166
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
4-{2-[4-(1-Hydroxy-1-methyl-ethyl)-phenyl]-thiophen-3-yl}-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL302687; BDBM50285222
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[36] | |||
| Compound Name |
(E)-N-Tert-butyl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333746; BDBM50429281
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
N-(4-Methylphenyl)sulfonylpyridine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1916965; N-Tosylpicolinamide; SCHEMBL7232680; ZINC1418751; BDBM50357959; STL439088; AKOS005223225; MCULE-9512014814; N-(p-toluenesulfonyl)pyrid-2-yl-carboxamide; N-[(4-methylphenyl)sulfonyl]pyridine-2-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[31] | |||
| Compound Name |
Chembl4241591
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50463063
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[37] | |||
| Compound Name |
6-(4-Methanesulfonyl-phenyl)-5-phenyl-imidazo[2,1-b]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL150006; SCHEMBL3240378; BDBM50289312; 6-(4-methylsulfonylphenyl)-5-phenylimidazo[2,1-b][1,3]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
4-(4-Methanesulfonyl-phenyl)-5-phenyl-[1,3]dioxol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL170639; BDBM50286948
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
4-[2-(4-Fluoro-phenyl)-thiophen-3-yl]-N-methyl-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL292948; BDBM50285212
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[36] | |||
| Compound Name |
N-(4-Fluorophenylsulfonyl)Isonicotinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1916957; BDBM50357962
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[31] | |||
| Compound Name |
Hederasaponin B
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Eleutheroside M; Hederacoside B; CHEMBL506880; Tauroside G2; Glycoside L-G2; Akebasaponin PJ3; Kizutasaponin K12; SCHEMBL2996335; HY-N0306; BDBM50259663; MFCD16036216; AKOS015894325; CS-0008804; Y0103
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
4-[3-(4-Fluoro-phenyl)-5-(1-hydroxy-1-methyl-ethyl)-thiophen-2-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL303674; BDBM50285211
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[36] | |||
| Compound Name |
1-(3,4-Difluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1H-tetrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL443819; BDBM50286939
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
Chembl4239825
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50463079
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[37] | |||
| Compound Name |
N-Tosylisonicotinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1916960; SCHEMBL10746521; BDBM50357952; N-(4-methylphenyl)sulfonylpyridine-4-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[31] | |||
| Compound Name |
6-(3,5-Difluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazolo[3,2-b][1,2,4]triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL155980; BDBM50289330
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[34] | |||
| Compound Name |
3-Oxaheneicosa-5,9,12,15,18-pentaenoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL458707; BDBM50269643
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[7] | |||
| Compound Name |
N-Acetyl-4-[2-(4-fluoro-phenyl)-thiophen-3-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL63706; BDBM50285206
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[36] | |||
| Compound Name |
Pallidol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL480462; Rel-Pallidol; (+/-)-Pallidol; SCHEMBL13169545; CTK7J8565; BDBM50259652; ZINC32052445; Q6634710
Click to Show/Hide
|
||||
| Activity |
IC50 = 50000 nM
|
[39] | |||
| Compound Name |
Clematichinenoside B
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1171453; BDBM50322746
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
N-[6-(2,6-Difluoro-phenylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL143781; BDBM50048197; N-[6-[(2,6-Difluorophenyl)thio]-1-oxoindan-5-yl]methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
5-(4-Methanesulfonyl-phenyl)-3-methyl-6-phenyl-imidazo[2,1-b]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL149076; SCHEMBL3242224; BDBM50289305; 3-methyl-5-(4-methylsulfonylphenyl)-6-phenylimidazo[2,1-b][1,3]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
4-[2-(4-Fluoro-phenyl)-thiophen-3-yl]-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL302663; BDBM50285224
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[36] | |||
| Compound Name |
Cussonoside B
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Cirensenoside O; CHEMBL1171448; BDBM50322753; Oleanolic acid 28-O-(rhamnopyranosyl(1-4)glucopyranosyl(1-6))glucopyranosyl ester; A822854
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-(4-phenylpiperidin-1-yl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333736; BDBM50429270
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
3-N,5-N-Bis-(4-methylphenyl)sulfonylpyridine-3,5-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1916956; BDBM50357961
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[31] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-dipentylprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334132; BDBM50429290
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
Kizuta Saponin K12
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1171449; BDBM50322749
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-bis(2-methylpropyl)prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334131; BDBM50429291
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
Huzhangoside D
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1171451; Huzhangoside-D; DTXSID101019960; BDBM50322747
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
N-(Phenylsulfonyl)nicotinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1916947; N-(benzenesulfonyl)pyridine-3-carboxamide; Oprea1_801019; SCHEMBL10718560; ZINC1418749; BDBM50357972; STL439089; AKOS002239805; MCULE-2181102490; N-(phenylsulfonyl)pyridine-3-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[31] | |||
| Compound Name |
4-(4-Methanesulfonyl-phenyl)-5,5-dimethyl-3-phenoxy-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL109177; SCHEMBL4575651; CTK0E1703; DTXSID00433258; BDBM50082346; 5,5-dimethyl-4-(4-methylsulfonylphenyl)-3-phenoxyfuran-2-one; 2(5H)-Furanone, 5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-3-phenoxy-; 3-Phenoxy-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[32] | |||
| Compound Name |
6-(4-Methanesulfonyl-phenyl)-2-methyl-5-phenyl-imidazo[2,1-b]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL149040; SCHEMBL7836982; BDBM50289314; 2-methyl-6-(4-methylsulfonylphenyl)-5-phenylimidazo[2,1-b][1,3]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[28] | |||
| Compound Name |
5-(4-Methanesulfonyl-phenyl)-2-methyl-6-phenyl-thiazolo[3,2-b][1,2,4]triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL348087; BDBM50289319
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[34] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-prop-2-ynylprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333744; BDBM50429283
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
Chembl4242033
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50463083
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[37] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-octylprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334143; BDBM50429286
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-(3-methylpiperidin-1-yl)prop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334137; BDBM50429275
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
6-(3-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazolo[3,2-b][1,2,4]triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL157820; BDBM50289317
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[34] | |||
| Compound Name |
3-(3,4-Difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5H)-furanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MF-tricyclic; MF Tricyclic; CHEMBL18264; 4-(3,4-difluorophenyl)-3-(4-methylsulfonylphenyl)-2H-furan-5-one; SCHEMBL2159864; CTK4D1049; DTXSID30167291; BDBM50078688; 2(5H)-Furanone, 3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-; 3-(3,4-Difluorophenyl)-4-(4-Methylsulfonylphenyl)-5H-Furan-2-One; 2(5H)-Furanone,3-(3,4-difluorophenyl)-4-[4-(methylsulfonyl)phenyl]-; 3 -(3,4- Difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone; 3-(3,4-Difluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5H-furan-2-one; 3-(3,4-Difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone; 3-(3,4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one; 3-(3.4-difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5h)-furanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[38] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-(3,4,5-trimethoxyphenyl)prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333753; BDBM50429296
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
Clematiunicinoside E
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Clematomandshurica Saponin C; CHEMBL1171454; BDBM50322744
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-dimethylprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333754; BDBM50429295
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
Cussonoside A
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL540943; Kizuta Cirensenoside O Saponin K3; Pulsatiloside C; HN saponin H; BDBM50322752; Hederagenin 28-O-(rhamnopyranosyl(1-4)glucopyranosyl(1-6))glucopyranosyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333741; BDBM50429265
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
6-(4-Methanesulfonyl-phenyl)-5-phenyl-thiazolo[3,2-b][1,2,4]triazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL346094; SCHEMBL3246872; BDBM50289325
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[34] | |||
| Compound Name |
Cauloside D
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Hederacoside D; Kizuta Saponin K10; CHEMBL538919; BDBM50322750; MFCD22572710; s9011; AKOS037514688; ACN-035199; CCG-270630; Y0102; Q27137714
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[33] | |||
| Compound Name |
[3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-yl]-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL355781; BDBM50286947
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-(3-morpholin-4-ylpropyl)prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333752; BDBM50429297
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-diethylprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333755; BDBM50429294
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-N-propylprop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2334140; BDBM50429263
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
N-(Phenylsulfonyl)Picolinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1916961; SCHEMBL7226092; BDBM50357954; N-(benzenesulfonyl)pyridine-2-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[31] | |||
| Compound Name |
(E)-3-[2,4-Dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]-1-morpholin-4-ylprop-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333738; BDBM50429268
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
(E)-N-Cyclopropyl-3-[2,4-dimethoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]phenyl]prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2333749; BDBM50429278
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[29] | |||
| Compound Name |
1-(3-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole-3-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391054; BDBM50492035
Click to Show/Hide
|
||||
| Activity |
IC50 = 50500 nM
|
[40] | |||
| Compound Name |
3-[[4-(4-Methoxyphenyl)piperazin-1-yl]methyl]-6,6-dimethyl-4-phenyl-4,5-dihydrooxazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3596281
Click to Show/Hide
|
||||
| Activity |
IC50 = 50600 nM
|
[41] | |||
| Compound Name |
(4S,4Ar,8aR)-3-(carbazol-9-ylmethyl)-4-(4-methoxyphenyl)-4a,5,6,7,8,8a-hexahydro-4H-1,2-benzoxazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3596288
Click to Show/Hide
|
||||
| Activity |
IC50 = 50800 nM
|
[41] | |||
| Compound Name |
(2S)-2-[4-[[(1S,2R)-2-Hydroxycyclopentyl]methyl]phenyl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL19286; BDBM50140316; (S)-2-[4-((1S,2R)-2-Hydroxy-cyclopentylmethyl)-phenyl]-propionic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[42] | |||
| Compound Name |
4'-Fluorostilbene-3,5-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL451311; Stilbene, 8f; SCHEMBL1486726; SCHEMBL1486728; BDBM50247272; ZINC34511033; 5-(4-fluorostyryl)benzene-1,3-diol; 5-[(e)-2-(4-fluorophenyl)ethenyl]-1,3-benzenediol; 5-[(E)-2-(4-fluorophenyl)ethenyl]benzene-1,3-diol
Click to Show/Hide
|
||||
| Activity |
IC50 = 51300 nM
|
[43] | |||
| Compound Name |
2-(2-Oxochromen-7-yl)oxyethyl 5-phenyl-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4079043; BDBM50269589
Click to Show/Hide
|
||||
| Activity |
IC50 = 51390 nM
|
[44] | |||
| Compound Name |
4-[(4-Hydroxyphenyl)iminomethyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL404476; BDBM50371741
Click to Show/Hide
|
||||
| Activity |
IC50 = 51830 nM
|
[20] | |||
| Compound Name |
2-Tert-butoxy-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL550537; BDBM50297691
Click to Show/Hide
|
||||
| Activity |
IC50 = 52000 nM
|
[5] | |||
| Compound Name |
4-[5-(4-Chloro-phenyl)-4-methanesulfonyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL281001; SCHEMBL6341624; BDBM50057521; 4-[5-(4-chlorophenyl)-4-methylsulfonylpyrazol-1-yl]benzenesulfonamide; 4-[4-(Methylsulfonyl)-5-(4-chlorophenyl)-1H-pyrazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 52000 nM
|
[45] | |||
| Compound Name |
2-(2,4-Difluorobenzyl)-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561888; BDBM50297700
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 52124 nM
|
[46] | |||
| Compound Name |
2-Isopropoxy-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551017; BDBM50297692
Click to Show/Hide
|
||||
| Activity |
IC50 = 52556 nM
|
[5] | |||
| Compound Name |
5-((1R,4Ar,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthren-1-yl)-pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL116532; BDBM50097204
Click to Show/Hide
|
||||
| Activity |
IC50 = 52600 nM
|
[47] | |||
| Compound Name |
2-(2-Oxochromen-7-yl)oxyethyl 5-(3-methoxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4076451; BDBM50269581
Click to Show/Hide
|
||||
| Activity |
IC50 = 52670 nM
|
[44] | |||
| Compound Name |
2-(2-Oxochromen-7-yl)oxyethyl 1-(4-sulfamoylphenyl)-5-(3,4,5-trimethoxyphenyl)pyrazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4082622; BDBM50269580
Click to Show/Hide
|
||||
| Activity |
IC50 = 53080 nM
|
[44] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(4-fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3823440; BDBM50185953
Click to Show/Hide
|
||||
| Activity |
IC50 = 53430 nM
|
[48] | |||
| Compound Name |
N-Methyl-4-[1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]aniline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43103; SCHEMBL5593889; BDBM50058000; {4-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-phenyl}-methyl-amine; 1-[4-(Methylsulfonyl)phenyl]-2-[4-(methylamino)phenyl]-4-(trifluoromethyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 53500 nM
|
[49] | |||
| Compound Name |
4-Thiazolidinone, 3,3'-(1,2-ethanediyl)bis[2-(4-methoxyphenyl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329688; ACMC-20ltz3; Oprea1_301109; Oprea1_508266; CTK3G5331; DTXSID50385071; BDBM50169818; AKOS000608785; AKOS016328554; CCG-253540; MCULE-2847748938; ST50338950
Click to Show/Hide
|
||||
| Activity |
IC50 = 53700 nM
|
[50] | |||
| Compound Name |
2-(4-(Methylsulfonyl)phenyl)-3-p-tolylthiazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399879; BDBM50221106
Click to Show/Hide
|
||||
| Activity |
IC50 = 53900 nM
|
[51] | |||
| Compound Name |
Sodium;2-[4-[(2-oxocyclopentyl)methyl]-3-phenylphenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814712
Click to Show/Hide
|
||||
| Activity |
IC50 = 54000 nM
|
[52] | |||
| Compound Name |
3-[[4-(2,3-Dichlorophenyl)piperazin-1-yl]methyl]-6,6-dimethyl-4-phenyl-4,5-dihydrooxazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3596286
Click to Show/Hide
|
||||
| Activity |
IC50 = 54900 nM
|
[41] | |||
| Compound Name |
4-(2-Thiophen-2-yl-4-trifluoromethyl-imidazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL321156; SCHEMBL5594830; BDBM50091197; 4-[2-thiophen-2-yl-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide; 4-[2-(2-Thienyl)-4-(trifluoromethyl)-1H-imidazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[53] | |||
| Compound Name |
4-[5-Phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Desmethyl Celecoxib; CHEMBL29920; 4-(5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide; PTPBS; SCHEMBL213784; CTK7B7042; BCP34247; CAY10452; ZINC2507610; BDBM50057518; Benzenesulfonamide, 4-[5-phenyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]-; HY-118139; CS-0065275; 4-(5-Phenyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide; 4-(5-Phenyl-3-trifluoromethyl-1H-pyrazol-1-yl)benzenesulfonamide; 1-HEXADECANOYL-2-(P-NITROPHENOXYSUCCINOYL)-SN-GLYCERYL-3-PHOSPHORYLCHOLINE
Click to Show/Hide
|
||||
| Activity |
IC50 = 55100 nM
|
[45] | |||
| Compound Name |
3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-2-methyl-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL362290; SCHEMBL5108776; BDBM50151775; 3-(4-fluorophenyl)sulfanyl-2-methyl-6-methylsulfonyl-1H-indole
Click to Show/Hide
|
||||
| Activity |
IC50 = 55700 nM
|
[54] | |||
| Compound Name |
Chembl4127794
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50276310
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[55] | |||
| Compound Name |
Chembl4127948
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50276369
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[55] | |||
| Compound Name |
Chembl4129984
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50276366
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[55] | |||
| Compound Name |
Chembl4126559
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50276360
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[55] | |||
| Compound Name |
(1R,4Ar,7S)-7-(2,2-Difluoro-ethyl)-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL153495; BDBM50097209
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[47] | |||
| Compound Name |
Chembl4129191
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50276367
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[55] | |||
| Compound Name |
Sodium;2-[3-(4-methylphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814713
Click to Show/Hide
|
||||
| Activity |
IC50 = 56000 nM
|
[52] | |||
| Compound Name |
4-(4-Fluoro-5-phenyl-pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL286277; SCHEMBL6338986; BDBM50057536; 4-(4-fluoro-5-phenylpyrazol-1-yl)benzenesulfonamide; 4-(4-Fluoro-5-phenyl-1H-pyrazole-1-yl)benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 56500 nM
|
[45] | |||
| Compound Name |
2-(2-Oxochromen-7-yl)oxyethyl 5-(3-chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4069891; BDBM50269577
Click to Show/Hide
|
||||
| Activity |
IC50 = 56520 nM
|
[44] | |||
| Compound Name |
Methyl 4-[(4-sulfamoylphenyl)methylideneamino]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL255174; BDBM50371740
Click to Show/Hide
|
||||
| Activity |
IC50 = 56730 nM
|
[20] | |||
| Compound Name |
3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5-methoxy-5-methyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL18498; SCHEMBL7840462; BDBM50125628; 3-(4-Fluorophenyl)-4-[4-(methylsulfonyl)phenyl]-5-methoxy-5-methyl-2,5-dihydrofuran-2-one; 3-(4-fluorophenyl)-5-methoxy-5-methyl-4-(4-methylsulfonylphenyl)furan-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 57000 nM
|
[56] | |||
| Compound Name |
2-(2-Oxochromen-4-yl)oxyethyl 5-(3-methoxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4077653; BDBM50269586
Click to Show/Hide
|
||||
| Activity |
IC50 = 57260 nM
|
[44] | |||
| Compound Name |
3-(1,3-Benzodioxol-5-yl)-2-(4-methylsulfonylphenyl)-5-(trifluoromethyl)-3,4-dihydropyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3309818; BDBM50045696
Click to Show/Hide
|
||||
| Activity |
IC50 = 57530 nM
|
[57] | |||
| Compound Name |
1-[4,4-Di(fluoromethyl)-2-(4-methylsulfonylphenyl)-1-cyclopentenyl]-4-fluorobenzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL322045; SCHEMBL8652295; BDBM50037942; 1-[4,4-bis(fluoromethyl)-2-(4-fluorophenyl)cyclopent-1-en-1-yl]-4-(methylsulfonyl)benzene; 1-[4,4-bis(fluoromethyl)-2-(4-methylsulfonylphenyl)cyclopenten-1-yl]-4-fluorobenzene; 1-Fluoro-4-[2-[4-(methylsulfonyl)phenyl]-4,4-bis(fluoromethyl)-1-cyclopentenyl]benzene
Click to Show/Hide
|
||||
| Activity |
IC50 = 58000 nM
|
[58] | |||
| Compound Name |
3-Cyclohexyloxy-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL70104; SCHEMBL5203610; BDBM50080083; 3-Cyclohexyloxy-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one; 3-(Cyclohexyloxy)-4-[4-(methylsulfonyl)phenyl]-5,5-dimethylfuran-2(5H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 58000 nM
|
[22] | |||
| Compound Name |
2-(3-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL363102; BDBM50153998
Click to Show/Hide
|
||||
| Activity |
IC50 = 58300 nM
|
[15] | |||
| Compound Name |
N-Cyclohexyl-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561891; N-cyclohexyl-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine; N-cyclohexyl-4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine; SCHEMBL5675609; BDBM50297669
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 58400 nM
|
[5] | |||
| Compound Name |
3-(4-Methanesulfonyl-phenyl)-5-methyl-[2,3'']bipyridinyl
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329120; SCHEMBL4888583; BDBM50072060
Click to Show/Hide
|
||||
| Activity |
IC50 = 59000 nM
|
[59] | |||
| Compound Name |
Sanggenon D
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL464610; C40H36O12; SCHEMBL17675512; 8252AH; BDBM50377904
Click to Show/Hide
|
||||
| Activity |
IC50 = 59000 nM
|
[7] | |||
| Compound Name |
2-(2-Oxochromen-4-yl)oxyethyl 5-(4-nitrophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4092434; BDBM50269588
Click to Show/Hide
|
||||
| Activity |
IC50 = 59060 nM
|
[44] | |||
| Compound Name |
2-(2-Oxochromen-4-yl)oxyethyl 5-phenyl-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4065986; BDBM50269573
Click to Show/Hide
|
||||
| Activity |
IC50 = 59230 nM
|
[44] | |||
| Compound Name |
4-[3-(2-Methylphenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410355; BDBM50075032
Click to Show/Hide
|
||||
| Activity |
IC50 = 59360 nM
|
[60] | |||
| Compound Name |
(4S,4Ar,8aR)-3-(carbazol-9-ylmethyl)-4-phenyl-4a,5,6,7,8,8a-hexahydro-4H-1,2-benzoxazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3596287
Click to Show/Hide
|
||||
| Activity |
IC50 = 59900 nM
|
[41] | |||
| Compound Name |
4-((3,4-Dihydroxyphenyl)diazenyl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL386992; NSC720347; 4-(3,4-dihydroxy-phenylazo)-benzenesulfonic acid amide; BDBM50190334; NSC-720347; NCI60_041224; 4-(3,4-Dihydroxyphenylazo)benzenesulfonamide; 4-(3,4-Dihydroxy-phenylazo)-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 59960 nM
|
[24] | |||
| Compound Name |
2-(2-Oxochromen-7-yl)oxyethyl 5-(4-methylphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4075969; BDBM50269591
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[44] | |||
| Compound Name |
3-(2,4-Difluoro-phenylsulfanyl)-6-methanesulfonyl-1H-indole-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL184764; SCHEMBL5108792; BDBM50151764; 3-(2,4-difluorophenyl)sulfanyl-6-methylsulfonyl-1H-indole-2-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[54] | |||
| Compound Name |
4-(6-Benzyl-benzo[1,3]dioxol-5-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL151042; BDBM50136106
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[61] | |||
| Compound Name |
2-(2-Oxochromen-4-yl)oxyethyl 5-(4-methylphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4084887; BDBM50269575
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[44] | |||
| Compound Name |
5-Benzyl-6-(4-methanesulfonyl-phenyl)-benzo[1,3]dioxole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL358246; SCHEMBL5723554; BDBM50136105
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[61] | |||
| Compound Name |
2-Ethyl-4-cyclohexyl-5-[4-(methylsulfonyl)phenyl]oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL161590; SCHEMBL8376310; BDBM50107521; 4-Cyclohexyl-2-ethyl-5-(4-methanesulfonyl-phenyl)-oxazole; 4-cyclohexyl-2-ethyl-5-(4-methylsulfonylphenyl)-1,3-oxazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[62] | |||
| Compound Name |
2-(2-Oxochromen-7-yl)oxyethyl 5-(4-chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4069692; BDBM50269592
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 60000 nM
|
[44] | |||
| Compound Name |
N-[3-(3-Ethylphenylamino)-4-pyridinyl]methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1078378; BDBM50311377
Click to Show/Hide
|
||||
| Activity |
IC50 = 60390 nM
|
[63] | |||
| Compound Name |
4-Methoxy-N-(4-sulfamoylbenzylidene)aniline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL257489; Oprea1_798125; SCHEMBL5311501; BDBM50371754; 4-[(4-methoxyphenyl)iminomethyl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 60740 nM
|
[20] | |||
| Compound Name |
1-(2-(4-(2-Nitrophenoxy)-phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775087; BDBM50343925
Click to Show/Hide
|
||||
| Activity |
IC50 = 61000 nM
|
[64] | |||
| Compound Name |
1-(3,5-Difluorophenyl)-2-[4-(methylsulfonyl)phenyl]cyclopentene-5-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL24009; 2-(3,5-difluorophenyl)-3-(4-methylsulfonylphenyl)cyclopent-2-en-1-one; SCHEMBL220107; BDBM50075664; 2-(3,5-Difluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone; 2-(3,5-Difluorophenyl)-3-(4-(methylsulfonyl)phenyl)-2-cyclopenten-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 61000 nM
|
[65] | |||
| Compound Name |
4-((3,4-Dimethoxyphenyl)diazenyl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL213326; NSC722839; CTK6J5006; BDBM50190336; NSC-722839; 4-(3,4-Dimethoxy-phenylazo)-benzenesulfonamide; 4-[(e)-(3,4-dimethoxyphenyl)diazenyl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 61730 nM
|
[24] | |||
| Compound Name |
Furan L
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL456235; BDBM50275173
Click to Show/Hide
|
||||
| Activity |
IC50 = 62000 nM
|
[27] | |||
| Compound Name |
N-(4-Aminophenyl)-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL260566; SCHEMBL3454009; CTK7D7665; BBL031508; BDBM50376388; STL387826; ZINC19406336; AKOS000114266; MCULE-7915776329; BB 0244048; H5295; N-(4-Amino-phenyl)-3-trifluoromethyl-benzam ide
Click to Show/Hide
|
||||
| Activity |
IC50 = 62000 nM
|
[66] | |||
| Compound Name |
Mulberrin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Kuwanon C; Norartocarpin; Kuwanonc; KUWANON-C; 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methylbut-2-enyl)chromen-4-one; CHEMBL518543; Kuwanon C, 4; Mulberrin (Kuwanon C); MEGxp0_001037; SCHEMBL3680736; ACon0_000342; ACon1_001122; DTXSID20212148; HY-N3513; BDBM50242015; LMPK12110895; ZINC14727558; AKOS032948822; MCULE-4706134068; AK168907; CS-0023685; FT-0775770; BRD-K55131635-001-01-3
Click to Show/Hide
|
||||
| Activity |
IC50 = 62000 nM
|
[7] | |||
| Compound Name |
3-(3,5-Dihydroxyphenyl)-7-hydroxycoumarin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL200198; BDBM50176525; 7-hydroxy-3-(3'',5''-dihydroxyphenyl)coumarin
Click to Show/Hide
|
||||
| Activity |
IC50 = 62300 nM
|
[67] | |||
| Compound Name |
(R)-8-Methyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1290801; SCHEMBL5646952; BDBM50331075; (2r)-8-methyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2h-chromene-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 62700 nM
|
[68] | |||
| Compound Name |
5-Chloro-3-(4-methanesulfonyl-phenyl)-[2,2'']bipyridinyl
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94939; SCHEMBL4889545; BDBM50072058
Click to Show/Hide
|
||||
| Activity |
IC50 = 63000 nM
|
[59] | |||
| Compound Name |
4-[5-(3,5-Difluoro-4-methoxy-phenyl)-3-difluoromethyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29456; SCHEMBL6339701; BDBM50057516; 4-[5-(3,5-difluoro-4-methoxyphenyl)-3-(difluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 63600 nM
|
[45] | |||
| Compound Name |
2-Methyl-3-(4-fluorobenzyl)-6-(methylsulfonyl)-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL362138; SCHEMBL5115827; 3-[(4-fluorophenyl)methyl]-2-methyl-6-methylsulfonyl-1H-indole; BDBM50151763; 3-(4-Fluoro-benzyl)-6-methanesulfonyl-2-methyl-1H-indole
Click to Show/Hide
|
||||
| Activity |
IC50 = 63900 nM
|
[54] | |||
| Compound Name |
2-[(2Z)-3,7-Dimethylocta-2,6-dienyl]-6-methylcyclohexa-2,5-diene-1,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL442564
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[7] | |||
| Compound Name |
Osthenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
UNII-7X6RF2708X; 7-hydroxy-8-(3-methylbut-2-enyl)chromen-2-one; 7-hydroxy-8-prenylcoumarin; CHEMBL350475; 7-Hydroxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one; 7X6RF2708X; 2H-1-Benzopyran-2-one, 7-hydroxy-8-(3-methyl-2-butenyl)-; 7-Hydroxy-8-prenylcoumarin; NSC 625328; 8-prenylumbelliferone; SCHEMBL51013; MEGxp0_000219; ACon1_000810; 7-hydroxy-8-(3-methylbut-2-en-1-yl)-2H-chromen-2-one; DTXSID80197508; BCP24741; ZINC1618130; 7-hydroxy--2H-1-benzopyran-2-one; BDBM50240868; MFCD03427690; NSC625328; AKOS025402390; AC-8807; MCULE-1778235745; NSC-625328; 8-(3-methylbut-2-en-1-yl)umbelliferone; NCI60_007807; 7-hydroxy-8-(3-methyl-but-2-enyl)coumarin; FT-0777401; C18080; 7-Hydroxy-8-(3-methyl-but-2-enyl)-chromen-2-one; BRD-K53399718-001-01-8; Q27155413; 7-Hydroxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one, 9CI; NCGC00169337-02!7-hydroxy-8-(3-methylbut-2-enyl)chromen-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[7] | |||
| Compound Name |
2-(3,7-Dimethylocta-2,6-dien-1-yl)-6-methylbenzo-1,4-quinone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL470129; BDBM50259940; 2-[(2E)-3,7-Dimethyl-2,6-octadienyl]-6-methyl-1,4-benzoquinone; 2,5-cyclohexadiene-1,4-dione, 2-(3,7-dimethyl-2,6-octadienyl)-6-methyl-; 2-[(2e)-3,7-dimethyl-2,6-octadienyl]-6-methyl-2,5-cyclohexadiene-1,4-dione; 2-[(2E)-3,7-dimethyl-2,6-octadienyl]-6-methyl-2,5-cyclohexadine-1,4-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 64300 nM
|
[69] | |||
| Compound Name |
4-[[4-(Dimethylamino)phenyl]iminomethyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL408865; BDBM50371748
Click to Show/Hide
|
||||
| Activity |
IC50 = 64420 nM
|
[20] | |||
| Compound Name |
3-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-(4-methylsulfonylphenyl)-5-(trifluoromethyl)-3,4-dihydropyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3309451; BDBM50045697
Click to Show/Hide
|
||||
| Activity |
IC50 = 64910 nM
|
[57] | |||
| Compound Name |
N-(4-Fluorophenyl)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561086; BDBM50297678
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 65800 nM
|
[5] | |||
| Compound Name |
N-(2-(1-(4-Bromobenzyl)-5-methoxy-2-methyl-1H-indol-3-yl)ethyl)-4-chlorobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL254377; BDBM50207445
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 66000 nM
|
[21] | |||
| Compound Name |
1h-Indole-3-acetic acid,1-(4-chlorobenzoyl)-5-methoxy-2-methyl-,2-phenylethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL95643; Indomethacin derivative, 20; BDBM22967; ZINC14979657; 1-(4-Chlorobenzoyl)-2-methyl-5-methoxy-1H-indole-3-acetic acid phenethyl ester; 2-phenylethyl 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 66000 nM
|
[21] | |||
| Compound Name |
2-(1-(4-Bromobenzyl)-5-methoxy-2-methyl-1H-indol-3-yl)ethyl 4-chlorobenzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL404107; BDBM50207449
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 66000 nM
|
[21] | |||
| Compound Name |
Falcarindiol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(3R,8S)-Falcarindiol; (3S,8S)-Falcarindiol; (+)-(3R,8S)-Falcarindiol; AC1NQY3Z; (3R,8S,9Z)-heptadeca-1,9-dien-4,6-diyne-3,8-diol; CHEMBL69018; 1,9-Heptadecadiene-4,6-diyne-3,8-diol; Heptadeca-1,9-diene-4,6-diyne-3,8-diol; SCHEMBL40935; HY-N1976; ZINC8214562; BDBM50071370; LMFA05000658; s3292; AKOS032948569; CS-0018296; W1875; C08449; Heptadeca-1,9(Z)-diene-4,6-diyne-3,8-diol; 297H875; Q-100631; Q5431681; (3R,8S,)-heptadeca-1,9-dien-4,6-diyne-3,8-diol; (3r,8s,9z)-heptadeca-1,9-dien-4,6-diyn-3,8-diol; (Z)-(3R,8S)-Heptadeca-1,9-diene-4,6-diyne-3,8-diol; (Z)-(3S,8S)-Heptadeca-1,9-diene-4,6-diyne-3,8-diol
Click to Show/Hide
|
||||
| Activity |
IC50 = 66000 nM
|
[7] | |||
| Compound Name |
4-(3-Hydroxy-4-methoxy-phenylazo)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL213266; NSC722841; CTK7A7104; BDBM50190340; NSC-722841; 4-((3-hydroxy-4-methoxyphenyl)diazenyl)benzenesulfonamide; 4-[(e)-(3-hydroxy-4-methoxyphenyl)diazenyl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 66410 nM
|
[24] | |||
| Compound Name |
6-Chloro-5-ethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630233; SCHEMBL5646930; BDBM50332745
Click to Show/Hide
|
||||
| Activity |
IC50 = 66700 nM
|
[70] | |||
| Compound Name |
3-(2-Chloro-phenylsulfanyl)-6-methanesulfonyl-1H-indole-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL183294; SCHEMBL5103128; BDBM50151768; 3-(2-chlorophenyl)sulfanyl-6-methylsulfonyl-1H-indole-2-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 67000 nM
|
[54] | |||
| Compound Name |
2-[3-Fluoro-5-(trifluoromethyl)phenyl]-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43640; SCHEMBL8886839; BDBM50057981; 2-(3-Fluoro-5-trifluoromethyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[49] | |||
| Compound Name |
4-[2-(3-Fluorophenyl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43672; SCHEMBL5594645; BDBM50057970; 4-[2-(3-Fluoro-phenyl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide; 4-[2-(3-Fluorophenyl)-4-(trifluoromethyl)-1H-imidazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 67700 nM
|
[49] | |||
| Compound Name |
6-Chloro-5-phenyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630237; SCHEMBL5645637; BDBM50332750
Click to Show/Hide
|
||||
| Activity |
IC50 = 68400 nM
|
[70] | |||
| Compound Name |
4-[3-(2-Methoxyphenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410356; BDBM50075033
Click to Show/Hide
|
||||
| Activity |
IC50 = 68490 nM
|
[60] | |||
| Compound Name |
2-(Cyclopentylmethoxy)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551419; SCHEMBL4721193; BDBM50297683; 2-(cyclopentylmethoxy)-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidine
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[5] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(3,4-dimethoxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3822638; BDBM50185924
Click to Show/Hide
|
||||
| Activity |
IC50 = 69250 nM
|
[48] | |||
| Compound Name |
3-(3-Fluorophenyl)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL321217; SCHEMBL439345; BDBM50082344; NCGC00487353-02; J-011375; 3-(3-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one; 3-(3-Fluorophenyl)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one; 3-(3-fluorophenyl)-5,5-dimethyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone; 5,5-Dimethyl-3-(3-fluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2-(5H)-furanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 70000 nM
|
[32] | |||
| Compound Name |
2-(2-Chlorophenyl)-4-(2,4-difluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17043; SCHEMBL7842478; BDBM50076870; 2-(2-Chloro-phenyl)-4-(2,4-difluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazole; 2-(2-chlorophenyl)-4-(2,4-difluorophenyl)-5-(4-methylsulfonylphenyl)-1,3-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[71] | |||
| Compound Name |
4-(5-Benzo[b]thiophen-3-yl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29397; BDBM50057578; 4-[5-(1-benzothiophen-3-yl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 70700 nM
|
[45] | |||
| Compound Name |
2-Methyl-3-(4-chlorobenzyl)-6-(methylsulfonyl)-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL185528; SCHEMBL5117847; 3-[(4-chlorophenyl)methyl]-2-methyl-6-methylsulfonyl-1H-indole; BDBM50151766; 3-(4-Chloro-benzyl)-6-methanesulfonyl-2-methyl-1H-indole
Click to Show/Hide
|
||||
| Activity |
IC50 = 71100 nM
|
[54] | |||
| Compound Name |
1-(3,4-Difluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole-3-carbaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391048; BDBM50492034
Click to Show/Hide
|
||||
| Activity |
IC50 = 71400 nM
|
[40] | |||
| Compound Name |
4-[2-(3-Fluoro-4-methoxyphenyl)phenyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL442166; SCHEMBL6725509; ZINC3814663; BDBM50049661; 3''-Fluoro-4''-methoxy-1,1':2',1''-terbenzene-4-sulfonamide; 3-Fluoro-4-methoxy-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide; 3''''''''-Fluoro-4''''''''-methoxy-[1,1'''';2'''',1'''''''']terphenyl-4-sulfonic acid amide
Click to Show/Hide
|
||||
| Activity |
IC50 = 71600 nM
|
[72] | |||
| Compound Name |
4-[2-(3,5-Dichloro-4-methoxyphenyl)-1-cyclopentenyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL321643; BDBM50029607; ZINC13744284; 4-[2-(3,5-Dichloro-4-methoxy-phenyl)-cyclopent-1-enyl]-benzenesulfonamide; 4-[2-(3,5-dichloro-4-methoxyphenyl)cyclopent-1-en-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 71600 nM
|
[73] | |||
| Compound Name |
(S)-8-Propyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1289129; SCHEMBL5644294; BDBM50331078; (2s)-8-propyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2h-chromene-3-carboxylic acid
Click to Show/Hide
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||||
| Activity |
IC50 = 71700 nM
|
[68] | |||
| Compound Name |
N-(2-Aminophenyl)-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL261266; N-(2-aminophenyl)[3-(trifluoromethyl)phenyl]carboxamide; CTK7F7753; ZINC140737; ALBB-018660; 2527AE; BBL015557; BDBM50376390; MFCD02656545; SBB012651; STK767113; AKOS000151377; MCULE-3104085011; ST038841; N-(2-Amino-phenyl)-3-trifluoromethyl-benzamide; SR-01000537034; benzamide, N-(2-aminophenyl)-3-(trifluoromethyl)-; N~1~-(2-aminophenyl)-3-(trifluoromethyl)benzamide; SR-01000537034-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[66] | |||
| Compound Name |
Salidroside
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Rhodioloside; Rhodosin; UNII-M983H6N1S9; MFCD00210553; 2-(4-Hydroxyphenyl)ethyl beta-D-glucopyranoside; CHEMBL465208; p-Hydroxyphenethyl glucopyranoside; M983H6N1S9; DSSTox_CID_28960; DSSTox_RID_83225; DSSTox_GSID_49034; Glucopyranoside, p-hydroxyphenethyl; Tyrosol glucoside; Salidroside,(S); NCGC00169145-02; pyran-3,4,5-triol; salidroside (rhodioloside); Salidroside - Rhodioloside; beta-D-Glucopyranoside, 2-(4-hydroxyphenyl)ethyl; MLS006010734; SCHEMBL148079; 8-O-b-D-glucoside of tyrosol; MEGxp0_000478; Salidroside, analytical standard; DTXSID4049034; ACon1_000366; HMS3884N15; HY-N0109; ZINC6092865; Tox21_113565; (4-hydroxyphenethoxy)tetrahydro-2H-; BDBM50269651; NSC741643; s2396; 4-hydroxyphenyl-2-ethylglucopyranoside; AKOS015895134; Tox21_113565_1; AC-6071; ACN-035412; CCG-267467; CM14012; CS-5300; MCULE-9369802025; NSC-741643; Salidroside, >=95% (LC/MS-ELSD); NCGC00169145-01; NCGC00169145-03; SC-17273; SMR001294679; AB0109060; N1789; SW219124-1; 2-(4-Hydroxyphenyl)ethyl ?-D-glucopyranoside; (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-; C06046; 2-(4-Hydroxyphenyl)ethyl bet.-D-glucopyranoside; p-Hydroxyphenethyl alcohol 1-O-beta-D-glucoside; 338S519; Q-100031; Q7404463; BRD-K66030860-001-01-0; Salidroside, primary pharmaceutical reference standard; Salidroside, United States Pharmacopeia (USP) Reference Standard
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[7] | |||
| Compound Name |
4-(2-Methyl-5-phenyl-4-thiazolyl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17062; SCHEMBL7832994; BDBM50076886; 4-(2-Methyl-5-phenyl-thiazol-4-yl)-benzenesulfonamide; 4-(2-methyl-5-phenyl-1,3-thiazol-4-yl)benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 72500 nM
|
[74] | |||
| Compound Name |
11S,16R-Dihydroxyoctadeca-9Z,17-dien-12,14-diynoic-1-ylacetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL464793; BDBM50269619
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[7] | |||
| Compound Name |
3-(4-Methanesulfonyl-phenyl)-2-pyridin-3-yl-cyclopent-2-enone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL24429; 3-(4-methylsulfonylphenyl)-2-pyridin-3-ylcyclopent-2-en-1-one; SCHEMBL7495373; CTK0E1545; DTXSID20430880; BDBM50075660; 2-(3-Pyridinyl)-3-(4-(methylsulfonyl)phenyl)-2-cyclopenten-1-one; 2-(3-Pyridyl)-3-[4-(methylsulfonyl)phenyl]-2-cyclopentene-1-one; 3-(4-(methylsulfonyl)phenyl)-2-(3-pyridinyl)-2-cyclopenten-1-one; 2-Cyclopenten-1-one, 3-[4-(methylsulfonyl)phenyl]-2-(3-pyridinyl)-
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[65] | |||
| Compound Name |
Sodium;2-[2-(4-methoxyphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814722
Click to Show/Hide
|
||||
| Activity |
IC50 = 74000 nM
|
[52] | |||
| Compound Name |
N-Methyl-4-(4-(methylsulfonyl)phenyl)-N-p-tolyl-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL559613; BDBM50297664
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 74175 nM
|
[5] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(3-fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3822695; BDBM50185952
Click to Show/Hide
|
||||
| Activity |
IC50 = 74300 nM
|
[48] | |||
| Compound Name |
3-(3,4-Dichloro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL18251; BDBM50125613; 3-(3,4-Dichlorophenyl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[56] | |||
| Compound Name |
Coniferin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Coniferyl alcohol beta-D-glucoside; UNII-M6616XLU2J; 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside; CHEMBL459056; M6616XLU2J; coniferyl alcohol-4-O-beta-D-glucopyranoside; Coniferoside; (E)-coniferin; C16H22O8; beta-D-Glucopyranoside, 4-(3-hydroxy-1-propenyl)-2-methoxyphenyl (VAN); bmse000608; MLS000563468; SCHEMBL321115; MEGxp0_000873; ACon1_002032; HMS2267N17; 3-(4-beta-D-Glucopyranosyloxy-3-methoxyphenyl)-2-propen-1-ol; HY-N3617; BDBM50269612; ZINC13132552; Coniferyl alcohol beta-delta-glucoside; AKOS032948392; MCULE-3230513022; 4-O-(beta-D-glucosyl)-trans-coniferol; NCGC00179896-01; NCGC00179896-02; SMR000470885; CS-0023945; C00761; Q358968; BRD-K70130576-001-01-7; 4-(3-Hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-delta-glucopyranoside
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[7] | |||
| Compound Name |
6-Chloro-8-(4-(ethylthio)phenyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1669037; SCHEMBL5642950; BDBM50336016; 6-chloro-8-(4-ethylsulfanylphenyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 75900 nM
|
[75] | |||
| Compound Name |
4-[4-Chloro-5-(4-ethoxy-3-fluoro-phenyl)-imidazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL117947; SCHEMBL6778835; BDBM50131645; 4-[4-chloro-5-(4-ethoxy-3-fluorophenyl)imidazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 76000 nM
|
[76] | |||
| Compound Name |
4-[5-(3,5-Dichloro-4-methoxy-phenyl)-3-difluoromethyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL287646; SCHEMBL6345445; BDBM50057544; 4-[5-(3,5-dichloro-4-methoxyphenyl)-3-(difluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 77000 nM
|
[45] | |||
| Compound Name |
4-[5-(3-Chloro-4-methylamino-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL30084; SCHEMBL6352715; BDBM50057541; 4-[5-[3-chloro-4-(methylamino)phenyl]-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide; 4-[3-(Trifluoromethyl)-5-[3-chloro-4-(methylamino)phenyl]-1H-pyrazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 77700 nM
|
[45] | |||
| Compound Name |
1-(4-Methanesulfonyl-phenyl)-2-m-tolyl-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL46712; SCHEMBL214198; BDBM50057987; 2-(3-methylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole; 1-[4-(Methylsulfonyl)phenyl]-2-(3-methylphenyl)-4-(trifluoromethyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 78000 nM
|
[53] | |||
| Compound Name |
Epicatechin-(4beta-8)-epiafzelechin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL447023; BDBM50269604; epiafzelechin-(4beta->8)-epicatechin
Click to Show/Hide
|
||||
| Activity |
IC50 = 78000 nM
|
[77] | |||
| Compound Name |
4-[3-(4-Methoxyphenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410357; BDBM50075035
Click to Show/Hide
|
||||
| Activity |
IC50 = 78100 nM
|
[60] | |||
| Compound Name |
4-[[3-Methoxy-4-hydroxybenzylidene]amino]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL270264; NSC722924; CBMicro_014280; ARONIS016362; SCHEMBL12416806; ZINC288484; SMSF0004896; BDBM50371759; STK034392; AKOS000483712; MCULE-2043900854; NSC-722924; KS-0000491D; ST012875; BIM-0014396.P001; SR-01000199557; SR-01000199557-1; 4-(4-hydroxy-3-methoxybenzylideneamino)benzenesulfonamide; 4-[(4-hydroxy-3-methoxybenzylidene)amino]benzenesulfonamide; (E)-4-(4-Hydroxy-3-methoxybenzylideneamino)benzenesulfonamide; 4-[(4-Hydroxy-3-methoxy-benzylidene)-amino]-benzenesulfonami de; 4-[(1E)-2-(4-hydroxy-3-methoxyphenyl)-1-azavinyl]benzenesulfonamide; 4-{[(E)-(4-hydroxy-3-methoxyphenyl)methylidene]amino}benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 78200 nM
|
[20] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(4-ethoxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3824071; BDBM50185926
Click to Show/Hide
|
||||
| Activity |
IC50 = 78540 nM
|
[48] | |||
| Compound Name |
4-[5-(2-Cyclohexylamino-pyridin-4-yl)-4-(4-fluoro-phenyl)-oxazol-2-yl]-piperidin-4-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL121405; BDBM50148690
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 80000 nM
|
[78] | |||
| Compound Name |
4-[1-[2-(Cyclopentylamino)pyrimidin-4-yl]-2-[3-(trifluoromethyl)phenyl]imidazol-4-yl]-1-methylpiperidin-4-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL118258; SCHEMBL6982664; BDBM50148694
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 80000 nM
|
[78] | |||
| Compound Name |
[4-(2,4-Difluoro-phenylamino)-phenyl]-(6-methoxy-2-methyl-3H-benzoimidazol-5-yl)-methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL120067; BDBM50148708
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 80000 nM
|
[79] | |||
| Compound Name |
4-(4-Fluorophenyl)-2-(1-methylpiperidin-4-yl)-5-(2-(1-(S)-Phenylethyl)amino-4-pyridinyl)thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2111784; SCHEMBL375202; BDBM50404281
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 80000 nM
|
[78] | |||
| Compound Name |
Cyclopentyl-{4-[2-(4-fluoro-phenyl)-5-(4-methyl-piperazin-1-yl)-imidazo[4,5-b]pyridin-1-yl]-pyrimidin-2-yl}-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL120185; SCHEMBL6485328; BDBM50148692
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 80000 nM
|
[78] | |||
| Compound Name |
[5-(3-Amino-3-methyl-but-1-ynyl)-2-methoxy-phenyl]-[4-(2,4-difluoro-phenylamino)-phenyl]-methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL419409; SCHEMBL5750795; BDBM50148709; [5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl]-[4-(2,4-difluoroanilino)phenyl]methanone; (5-(3-amino-3-methylbut-1-ynyl)-2-methoxyphenyl)(4-(2,4-difluorophenylamino)phenyl)methanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 80000 nM
|
[79] | |||
| Compound Name |
2-[[1-(4-Chlorophenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264693; BDBM50016433
Click to Show/Hide
|
||||
| Activity |
IC50 = 80820 nM
|
[80] | |||
| Compound Name |
4-[(3E,6E,9E,12E)-Pentadeca-3,6,9,12-tetraenyl]sulfanylbutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL510672; 5-thia-8,11,14,17-eicosatetraenoic acid; BDBM50269658
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[7] | |||
| Compound Name |
3-(3-Chloro-4-fluoro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL279268; BDBM50125618; 3-(3-Chloro-4-fluorophenyl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[56] | |||
| Compound Name |
5-Chloro-3-(4-methanesulfonyl-phenyl)-[2,4'']bipyridinyl
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL92793; SCHEMBL4888348; BDBM50072059
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[59] | |||
| Compound Name |
4-[5-(2,4-Dimethyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL283038; 2-Methyl-Celecoxib; 2,4-Dimethyl Celecoxib; SCHEMBL6352145; EX-A3207; BDBM50057525; ZINC13761827; 4-[5-(2,4-dimethylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 81800 nM
|
[45] | |||
| Compound Name |
4-[2-(3-Fluoro-5-methyl-phenyl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL417170; SCHEMBL214106; BDBM50057954; 4-[2-(3-fluoro-5-methylphenyl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide; 4-[2-(3-Methyl-5-fluorophenyl)-4-(trifluoromethyl)-1H-imidazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 82000 nM
|
[49] | |||
| Compound Name |
3-[1-(4-Methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]quinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL110446; SCHEMBL5594589; BDBM50091192; 1-[4-(Methylsulfonyl)phenyl]-2-(quinoline-3-yl)-4-(trifluoromethyl)-1H-imidazole; 3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-quinoline; x3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-quinoline
Click to Show/Hide
|
||||
| Activity |
IC50 = 82000 nM
|
[53] | |||
| Compound Name |
2-(1-Hydroxycyclopentylmethoxy)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL45583; SCHEMBL6657891; BDBM50078587; 1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-pyridin-2-yloxymethyl]-cyclopentanol
Click to Show/Hide
|
||||
| Activity |
IC50 = 83000 nM
|
[81] | |||
| Compound Name |
4-[2-(4-Methylpyridin-2-yl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL108961; SCHEMBL215247; BDBM50091176; 4-[2-(4-Methyl-2-pyridinyl)-4-(trifluoromethyl)-1H-imidazole-1-yl]benzenesulfonamide; 4-[2-(4-Methyl-pyridin-2-yl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 84000 nM
|
[53] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(4-methoxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3823400; BDBM50185922
Click to Show/Hide
|
||||
| Activity |
IC50 = 84270 nM
|
[48] | |||
| Compound Name |
(1R,4Ar,7S)-7-(2-Methoxy-ethyl)-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL153497; BDBM50097203
Click to Show/Hide
|
||||
| Activity |
IC50 = 84600 nM
|
[47] | |||
| Compound Name |
2-Hydroxy-5-[(4-sulfamoyl-phenylimino)-methyl]-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL405744; NSC722842; BDBM50371744; NSC-722842
Click to Show/Hide
|
||||
| Activity |
IC50 = 85130 nM
|
[20] | |||
| Compound Name |
4-[3-(3-Methoxyphenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410343; BDBM50074899
Click to Show/Hide
|
||||
| Activity |
IC50 = 85460 nM
|
[60] | |||
| Compound Name |
2-Methyl-5-(4-methylsulfonylphenyl)-1-phenyl-3-(2-propoxyethyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL517675; VA441; [2-Methyl-5-(4-methylsulphonyl)phenyl-1-phenyl-3-(2-n-propyloxyethyl)]-1H-pyrrole; SCHEMBL3824352; BDBM50262990; VA-441; ZINC40918711; DA-16463; FT-0723707
Click to Show/Hide
|
||||
| Activity |
IC50 = 86000 nM
|
[82] | |||
| Compound Name |
5-Ethyl-3-isopropoxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL443278; MK-0703; (S)-5-ethyl-3-isopropoxy-5-methyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one; SCHEMBL5180119; BDBM50120573; l-791515; (5S)-3-Isopropoxy-4-[4-(methylsulfonyl)phenyl]-5-ethyl-5-methylfuran-2(5H)-one; (5S)-5-ethyl-3-isopropoxy-5-methyl-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-one; (5S)-5-ethyl-5-methyl-4-(4-methylsulfonylphenyl)-3-propan-2-yloxyfuran-2-one; (S)-5-Ethyl-3-isopropoxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 86000 nM
|
[83] | |||
| Compound Name |
4-[3-(3-Hydroxyphenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410351; BDBM50074909
Click to Show/Hide
|
||||
| Activity |
IC50 = 86230 nM
|
[60] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(2-chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3822899; BDBM50185929
Click to Show/Hide
|
||||
| Activity |
IC50 = 86240 nM
|
[48] | |||
| Compound Name |
4-[3-(2-Chlorophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410359; BDBM50075037
Click to Show/Hide
|
||||
| Activity |
IC50 = 86760 nM
|
[60] | |||
| Compound Name |
N,N-Dimethyl-N'-[4-[4-[(Z)-[(Z)-[3-(4-methylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]hydrazinylidene]methyl]-3-phenylpyrazol-1-yl]phenyl]sulfonylmethanimidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL476870; BDBM50292564
Click to Show/Hide
|
||||
| Activity |
IC50 = 87120 nM
|
[84] | |||
| Compound Name |
N-(2-Aminophenyl)-4-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL259539; 2-{[4-(Trifluoromethyl)benzoyl]amino}aniline; N-(2-aminophenyl)[4-(trifluoromethyl)phenyl]carboxamide; CTK7F7010; ZINC140422; ALBB-018659; 2526AE; BBL005146; BDBM50376399; MFCD02656544; SBB012650; STK766630; AKOS000178078; MCULE-7310001561; ST038667; AB0223525; 2'-AMINO-4-TRIFLUOROMETHYLBENZANILIDE; EU-0019584; R6031; Benzamide, N-(2-aminophenyl)-4-trifluoromethyl-; N-(2-Amino-phenyl)-4-trifluoromethyl-benzamide; AG-205/40650194; SR-01000536301; benzamide, N-(2-aminophenyl)-4-(trifluoromethyl)-; SR-01000536301-1
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[66] | |||
| Compound Name |
2-[[1-(3-Chlorophenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264692; BDBM50016432
Click to Show/Hide
|
||||
| Activity |
IC50 = 88260 nM
|
[80] | |||
| Compound Name |
4-[3-(4-Methylphenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410341; BDBM50074891
Click to Show/Hide
|
||||
| Activity |
IC50 = 88380 nM
|
[60] | |||
| Compound Name |
4-[2-(6-Methylpyridin-3-yl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL108936; SCHEMBL215709; BDBM50091184; 4-[2-(6-Methyl-3-pyridinyl)-4-(trifluoromethyl)-1H-imidazole-1-yl]benzenesulfonamide; 4-[2-(6-Methyl-pyridin-3-yl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide; 4-[2-(6-methylpyridin-3-yl)-4-(trifluoromethyl)-1h-imidazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 89000 nM
|
[53] | |||
| Compound Name |
2-[[1-(4-Methoxyphenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264691; BDBM50016431
Click to Show/Hide
|
||||
| Activity |
IC50 = 89370 nM
|
[80] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(4-methylphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3823238; BDBM50185918
Click to Show/Hide
|
||||
| Activity |
IC50 = 89530 nM
|
[48] | |||
| Compound Name |
5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-phenyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL18316; SCHEMBL6331760; BDBM50125626; 5-hydroxy-5-methyl-4-(4-methylsulfonylphenyl)-3-phenylfuran-2-one; 5-Hydroxy-5-methyl-4-(4-(methylsulfonyl)phenyl)-3-phenyl-2-(5H)-furanone; 3-Phenyl-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[56] | |||
| Compound Name |
3-Benzyl-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL108802; SCHEMBL5207502; BDBM50082355; 3-Benzyl-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one; 3-Benzyl-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[32] | |||
| Compound Name |
3-(3,5-Difluoro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL416363; SCHEMBL7830502; BDBM50125609; 3-(3,5-difluorophenyl)-5-hydroxy-5-methyl-4-(4-methylsulfonylphenyl)furan-2-one; 3-(3,5-Difluorophenyl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 90000 nM
|
[56] | |||
| Compound Name |
4-[3-(2-Bromophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410361; BDBM50075039
Click to Show/Hide
|
||||
| Activity |
IC50 = 90230 nM
|
[60] | |||
| Compound Name |
1-(4-Methanesulfonyl-phenyl)-2-(4-methoxy-3,5-dimethyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43331; SCHEMBL5594060; BDBM50057913; 2-(4-methoxy-3,5-dimethylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 91000 nM
|
[49] | |||
| Compound Name |
6-Chloro-8-(4-sulfamoylphenyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1290433; SCHEMBL5646089; BDBM50331885; 8-[4-(aminosulfonyl)phenyl]-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 91400 nM
|
[75] | |||
| Compound Name |
4-[3-(3-Methylphenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410340; BDBM50074888
Click to Show/Hide
|
||||
| Activity |
IC50 = 91520 nM
|
[60] | |||
| Compound Name |
4-(4-Methylsulfonylphenyl)-N-(oxan-4-yl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL559886; SCHEMBL5826798; BDBM50297666; 4-(4-(methylsulfonyl)phenyl)-N-(tetrahydro-2H-pyran-4-yl)-6-(trifluoromethyl)pyrimidin-2-amine; 4-[4-(methylsulfonyl)phenyl]-N-tetrahydro-2H-pyran-4-yl-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 91629 nM
|
[5] | |||
| Compound Name |
2-Methyl-4-[4-(methylsulfonyl)phenyl]-5-(5-chloro-2-thienyl)oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL158509; SCHEMBL8377543; BDBM50107524; 5-(5-Chloro-thiophen-2-yl)-4-(4-methanesulfonyl-phenyl)-2-methyl-oxazole; 5-(5-chlorothiophen-2-yl)-2-methyl-4-(4-methylsulfonylphenyl)-1,3-oxazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[62] | |||
| Compound Name |
Sodium;2-[2-nitro-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814709
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[52] | |||
| Compound Name |
4-[5-Pyridin-2-yl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29075; SCHEMBL6353158; BDBM50057614; 4-(5-Pyridin-2-yl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 93300 nM
|
[45] | |||
| Compound Name |
2-(3,5-Difluoro-phenoxy)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL23610; SCHEMBL5204580; BDBM50075670; 2-(3,5-difluorophenoxy)-3-(4-methylsulfonylphenyl)cyclopent-2-en-1-one; 2-(3,5-Difluorophenoxy)-3-[4-(methylsulfonyl)phenyl]-2-cyclopentene-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 94000 nM
|
[65] | |||
| Compound Name |
N-(3-Aminophenyl)-2-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL261485; CTK7D9124; BDBM50376392; AKOS000131063
Click to Show/Hide
|
||||
| Activity |
IC50 = 94000 nM
|
[66] | |||
| Compound Name |
6-Ethynyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288538; SCHEMBL6092204; BDBM50331054
Click to Show/Hide
|
||||
| Activity |
IC50 = 94200 nM
|
[68] | |||
| Compound Name |
6,7-Dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288554; SCHEMBL212254; BDBM50331874
Click to Show/Hide
|
||||
| Activity |
IC50 = 94500 nM
|
[85] | |||
| Compound Name |
(+)-Gallocatechin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Gallocatechin; (+)-gallocatechol; Gallocatechol; d-Gallocatechin; UNII-HEJ6575V1X; (2R,3S)-gallocatechin; CHEMBL125743; HEJ6575V1X; (2R,3S)-2-(3,4,5-trihydroxyphenyl)chromane-3,5,7-triol; dl-Gallocatechin; (2R,3S)-3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol; 2H-1-Benzopyran-3,5,7-triol, 3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-,(2R,3S)-; (+-)-Gallocatechin; (+-)-Gallocatechol; Gallocatechol, (+-)-; Casuarin; C15H14O7; NSC674038; NSC 674038; MEGxp0_000240; SCHEMBL3872234; (2R,3S)-(+)-gallocatechin; ACon1_000994; HY-N0521A; DTXSID10914220; ZINC3870338; BDBM50135165; LMPK12020002; (2R,3S)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol; AKOS022180463; ACN-047610; CCG-267530; MCULE-4522193885; NSC-674038; NCGC00169777-01; NCI60_026203; CS-0022247; S9048; W1563; C12127; (2R,3S)-flavan-3,3',4',5,5',7-hexol; (2R,3S)-flavan-3,5,7,3',4',5'-hexol; (+)-trans-3,3',4',5,5',7-Hexahydroxyflavan; (2R,3S)-2-(3,4,5-Trihydroxy-phenyl)-chroman-3,5,7-triol; (2R,3S)-2-(3,4,5-Trihydroxy-phenyl)-1-benzopyran-3,5,7-triol; (2R*,3S*)- 3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3,5,7-triol; (2R*,3S*)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol; (2R,3S)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; 2H-1-Benzopyran-3,7-triol, 3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-, (2R-trans-); rel-(2R,3S)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[7] | |||
| Compound Name |
N-[(E)-(3-Benzyl-4-oxo-1,3-thiazolidin-2-ylidene)amino]-2-(2,4-dichlorophenoxy)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4098802; BDBM50235073
Click to Show/Hide
|
||||
| Activity |
IC50 = 95440 nM
|
[86] | |||
| Compound Name |
2-(4-(Methylsulfonyl)phenyl)-3-phenylthiazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL399878; SCHEMBL5671915; 2-(4-methylsulfonylphenyl)-3-phenyl-1,3-thiazolidin-4-one; BDBM50221105
Click to Show/Hide
|
||||
| Activity |
IC50 = 96100 nM
|
[51] | |||
| Compound Name |
N-Butyl-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL549393; BDBM50297672
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 96150 nM
|
[5] | |||
| Compound Name |
(2RS,4R)-2-(1-phenyl-3-p-tolyl-1H-pyrazol-4-yl)thiazolidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1631308; BDBM50332954
Click to Show/Hide
|
||||
| Activity |
IC50 = 96220 nM
|
[87] | |||
| Compound Name |
4-[3-(2-Methoxyphenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410342; BDBM50074892
Click to Show/Hide
|
||||
| Activity |
IC50 = 96240 nM
|
[60] | |||
| Compound Name |
N'-[4-[4-[(Z)-[(Z)-[4-(4-Bromophenyl)-3-(4-methylphenyl)-1,3-thiazol-2-ylidene]hydrazinylidene]methyl]-3-phenylpyrazol-1-yl]phenyl]sulfonyl-N,N-dimethylmethanimidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL508588; BDBM50292562
Click to Show/Hide
|
||||
| Activity |
IC50 = 96250 nM
|
[84] | |||
| Compound Name |
4-[3-(2,4-Dichlorophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410363; BDBM50075041
Click to Show/Hide
|
||||
| Activity |
IC50 = 96330 nM
|
[60] | |||
| Compound Name |
2-[(1-Pyridin-3-yltriazol-4-yl)methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264703; BDBM50016429
Click to Show/Hide
|
||||
| Activity |
IC50 = 96560 nM
|
[80] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(3,4-dichlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3824049; BDBM50185940
Click to Show/Hide
|
||||
| Activity |
IC50 = 96590 nM
|
[48] | |||
| Compound Name |
2-Methyl-3-(2,4-difluorobenzyl)-6-(methylsulfonyl)-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL183970; SCHEMBL5105676; 3-[(2,4-difluorophenyl)methyl]-2-methyl-6-methylsulfonyl-1H-indole; BDBM50151782; 3-(2,4-Difluoro-benzyl)-6-methanesulfonyl-2-methyl-1H-indole
Click to Show/Hide
|
||||
| Activity |
IC50 = 98000 nM
|
[54] | |||
| Compound Name |
3-Fluoro-5-[[1-(4-methylsulfonylphenyl)-5-phenylpyrazol-3-yl]methoxy]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL376711; BDBM50156587; 3-[(5-cyano-3-fluoro)phenoxymethyl]-1-(4-methanesulfonylphenyl)-5-phenyl-1H-pyrazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 99560 nM
|
[16] | |||
| Compound Name |
4-[3-(2-Chloro-6-fluorophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410354; BDBM50074912
Click to Show/Hide
|
||||
| Activity |
IC50 = 99840 nM
|
[60] | |||
| Compound Name |
4-[3-(2-Methylphenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410339; BDBM50074885
Click to Show/Hide
|
||||
| Activity |
IC50 = 99870 nM
|
[60] | |||
| Compound Name |
(1S,2R)-2-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-pyridin-2-yloxy]-1-methyl-cyclopentanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL47540; SCHEMBL6661828; BDBM50078589
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[81] | |||
| Compound Name |
4-(4-Chloro-3-methylphenyl)-1,2-difluoro-5-[4-(methylsulfonyl)phenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL57837; SCHEMBL6721531; BDBM50049617; 1-(4-chloro-3-methylphenyl)-4,5-difluoro-2-(4-methylsulfonylphenyl)benzene; 4-(Methylsulfonyl)-4''-chloro-4',5'-difluoro-5''-methyl-1,1':2',1''-terbenzene; 4-Chloro-4'',5''-difluoro-4''''-methanesulfonyl-3-methyl-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
(Z)-4-Amino-4-(5-chlorofuran-2-yl)-3-phenylbut-3-en-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380880; BDBM50491535
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[89] | |||
| Compound Name |
2-(Trifluoromethyl)-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL265585; SCHEMBL214771; BDBM50076872; 4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-2-(trifluoromethyl)-1,3-thiazole; 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-trifluoromethyl-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
3-Amino-N-[3-(trifluoromethyl)phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-Amino-N-(3-trifluoromethyl-phenyl)-benzamide; CHEMBL260564; 3-Amino-N-(3-(trifluoromethyl)phenyl)benzamide; (3-aminophenyl)-N-[3-(trifluoromethyl)phenyl]carboxamide; Enamine_000835; ARONIS015812; SCHEMBL4463935; CTK7D8742; DTXSID30368049; HMS1396F21; KS-000045XF; ZINC3184724; BDBM50376386; SBB042473; STL068885; AKOS000115425; MCULE-3576022033; NE36675; ST45052497; EN300-02326; Z56784365
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
3-Amino-N-[2-(trifluoromethyl)phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL442465; CTK7D8755; ZINC7468555; BDBM50376387; AKOS000151679
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
(2S)-6-Bromo-5,7-bis(trideuteriomethyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3355612; SCHEMBL19097645
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
4-[2-(3,4,5-Trifluorophenyl)-1-cyclopentenyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL336011; BDBM50029594; ZINC13744270; 4-[2-(3,4,5-Trifluoro-phenyl)-cyclopent-1-enyl]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[73] | |||
| Compound Name |
2-(Cyclohexylmethoxy)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL564729; BDBM50297682
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
4-(4-(Methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL558727; 4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine; SCHEMBL5785867; BDBM50297674; 4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
3-(3-Fluoro-4-methoxy-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL100422; BDBM50286052
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[91] | |||
| Compound Name |
1-(4-Fluorophenyl)-2-(4-methylsulfonylphenyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43210; 1-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-pyrrole; 1-[4-fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-pyrrole; SCHEMBL5309608; BDBM50057894; 1-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
2-(Cyclohexylamino)-6-(4-(methylsulfonyl)phenyl)pyrimidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL563759; BDBM50297694
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
N-(Methylsulfonyl)-N-(3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)-phenyl)methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775109; BDBM50343922
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
4-[8-Fluoro-7-methoxy-4-oxo-3-(trifluoromethyl)-5H-isothiochromeno[4,3-c]pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94274; BDBM50288328
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[93] | |||
| Compound Name |
Benzenesulfonamide,4-(4-cyclohexyl-2-methyl-5-oxazolyl)-n-methyl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL161793; SCHEMBL8376333; BDBM50107517; ZINC13436274; 4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-N-methyl-benzenesulfonamide; N-Methyl-4-[2-methyl-4-cyclohexyl-5-oxazolyl]benzenesulfonamide; 4-(4-CYCLOHEXYL-2-METHYL-1,3-OXAZOL-5-YL)-N-METHYLBENZENESULFONAMIDE
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[62] | |||
| Compound Name |
3-Mesityl-4-phenyl-5-methylisoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL442224; SCHEMBL13064922; BDBM50153042; ZINC13583261; 5-Methyl-4-phenyl-3-(2,4,6-trimethyl-phenyl)-isoxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[94] | |||
| Compound Name |
4-[3-(2-Chloro-6-fluorophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410364; BDBM50075042
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
4-[3-(2-Bromophenyl)-5-tert-butyl-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3922249; SCHEMBL12524148; BDBM236645; US9388139, 14
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
4-[5-Tert-butyl-3-(2-fluorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3906921; SCHEMBL12524132; BDBM236649; US9388139, 18
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-(3-Fluoro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL273340; SCHEMBL7829907; BDBM50125622; 3-(3-Fluorophenyl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one; 3-(3-fluorophenyl)-5-hydroxy-5-methyl-4-(4-methylsulfonylphenyl)furan-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
4-[2-(4-Trifluoromethoxy-phenyl)-pyrazolo[1,5-b]pyridazin-3-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL360182; BDBM50153993
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
4-(2-(4-Fluorophenyl)-1H-pyrrol-1-yl)-N-methylbenzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL298281; 4-[2-(4-fluorophenyl)-1H-pyrrol-1-yl]-N-methylbenzenesulfonamide; SCHEMBL5071002; CTK0A2865; DTXSID80441230; BDBM50057887; 4-[2-(4-Fluoro-phenyl)-pyrrol-1-yl]-N-methyl-benzenesulfonamide; 4-[2-(4-FLUOROPHENYL)PYRROL-1-YL]-N-METHYLBENZENESULFONAMIDE; Benzenesulfonamide, 4-[2-(4-fluorophenyl)-1H-pyrrol-1-yl]-N-methyl-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
3-[(4-Chlorophenoxy)methyl]-1-(4-fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44152; SCHEMBL7210642; BDBM50057869; 3-(4-Chloro-phenoxymethyl)-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrole; 3-[(4-chlorophenoxy)methyl]-1-(4-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
1-(3,4-Dimethoxyphenyl)-4,5-difluoro-2-(4-methylsulfonylphenyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL52889; SCHEMBL6726224; BDBM50049643; 1,2-difluoro-4-(3,4-dimethoxypheny)-5-[4(methylsulfonyl)phenyl]benzene; 1,2-difluoro-4-(3,4-dimethoxypheny)-5-[4-(methylsulfonyl)phenyl]benzene; 4'',5''-Difluoro-4''''-methanesulfonyl-3,4-dimethoxy-[1,1'';2'',1'''']terphenyl; 4-(Methylsulfonyl)-4',5'-difluoro-4'',5''-dimethoxy-1,1':2',1''-terbenzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
1-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-3-nitrooxymethyl-1H-pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL66435; BDBM50144866
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[95] | |||
| Compound Name |
1-[1-(4-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrol-3-yl]ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44290; SCHEMBL7210344; BDBM50057870; 1-[1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrol-3-yl]-ethanone; 1-[1-(4-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrol-3-yl]ethanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
2-{4-[4-Chloro-1-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl]-2-fluorophenoxy}ethyl Nitrate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL223619; BDBM50206929
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[96] | |||
| Compound Name |
2-(4-Chlorophenyl)-4-(methylsulfonylmethyl)-1-(4-methylsulfonylphenyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43217; SCHEMBL5698556; BDBM50057936; 2-(4-Chloro-phenyl)-4-methanesulfonylmethyl-1-(4-methanesulfonyl-phenyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
3,5-Diphenyl-1,2-oxazole-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380879; SCHEMBL2281353; BDBM50491539; AKOS013476179
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[89] | |||
| Compound Name |
2-(3-Fluoro-5-methyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42884; SCHEMBL215729; BDBM50057922; 2-(3-fluoro-5-methylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
6-[4-(Methylsulfonyl)phenyl]-5-[4-(trifluoromethyl)phenyl]spiro[2.4]hept-5-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329999; SCHEMBL8383616; BDBM50049037; 5-(4-Methanesulfonyl-phenyl)-6-(4-trifluoromethyl-phenyl)-spiro[2.4]hept-5-ene; 6-(4-methylsulfonylphenyl)-5-[4-(trifluoromethyl)phenyl]spiro[2.4]hept-5-ene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[97] | |||
| Compound Name |
2-(3,5-Difluoro-4-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42119; SCHEMBL5594188; BDBM50057946; 2-(3,5-difluoro-4-methoxyphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
4-[5-Tert-butyl-3-(3-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3912663; SCHEMBL12524159; BDBM236651; US9388139, 20
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N,N-Dimethyl-4-[1-(4-methylsulfonylphenyl)triazol-4-yl]aniline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL512916; BDBM50266483; {4-[1-(4-Methanesulfonylphenyl)-1H-[1,2,3]triazol-4-yl]-phenyl}-dimethylamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[98] | |||
| Compound Name |
2-Phenyl-4-[4-(methylsulfonyl)phenyl]-5-(4-fluorophenyl)thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL280496; BDBM50076865; 5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-2-phenyl-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
N-[6-(4,5-Dimethyl-thiazol-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL39013; BDBM50073868
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
4-(4-Difluoromethyl-2-pyridin-3-yl-imidazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL321407; SCHEMBL5594199; BDBM50091204; 4-[4-(difluoromethyl)-2-pyridin-3-ylimidazol-1-yl]benzenesulfonamide; 4-[2-(3-Pyridinyl)-4-(difluoromethyl)-1H-imidazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methoxy-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL36542; BDBM50111001
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
Methyl 5-(4-fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29576; SCHEMBL6342214; BDBM50057588; 5-(4-Fluoro-phenyl)-1-(4-sulfamoyl-phenyl)-1H-pyrazole-3-carboxylic acid methyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(4-hydroxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3823689; BDBM50185928
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[48] | |||
| Compound Name |
3-[4-Methyl-1-(4-methylsulfonylphenyl)imidazol-2-yl]pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL110448; SCHEMBL5594035; BDBM50091170; ZINC13812850; 3-[1-(4-Methanesulfonyl-phenyl)-4-methyl-1H-imidazol-2-yl]-pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1-phenethyl-5-trifluoromethyl-1H-pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL67659; SCHEMBL214172; BDBM50289969; 4-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)-1-(2-phenylethyl)-5-(trifluoromethyl)pyrazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[100] | |||
| Compound Name |
(R)-8-Ethyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1290803; SCHEMBL5172247; BDBM50331077; ZINC34659598; (2r)-8-ethyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2h-chromene-3-carboxylic acid; (R)-8-Ethyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid, AldrichCPR
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[68] | |||
| Compound Name |
3-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)aniline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775106; BDBM50343919
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
8-(4-Carboxyphenyl)-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1669031; SCHEMBL5770564; BDBM50336010
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[75] | |||
| Compound Name |
2-Methyl-4-cycloheptyl-5-[4-(methylsulfonyl)phenyl]oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL161728; SCHEMBL8380758; BDBM50107514; 4-cycloheptyl-2-methyl-5-(4-methylsulfonylphenyl)-1,3-oxazole; 4-Cycloheptyl-5-(4-methanesulfonyl-phenyl)-2-methyl-oxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[62] | |||
| Compound Name |
4-Chloro-5-(2-fluorophenyl)-1-(4-methylsulfonylphenyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL117650; SCHEMBL6294263; BDBM50131581; 4-Chloro-5-(2-fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[76] | |||
| Compound Name |
1-(4-Fluorophenyl)-2-(4-methylsulfonylphenyl)-5-(trifluoromethyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44447; SCHEMBL5312636; BDBM50057893; 1-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5-trifluoromethyl-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
4-[3-(4-Fluorophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410346; BDBM50074904
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
6-Chloro-7-((2,6-dimethylpiperidin-1-yl)methyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630247; 6-chloro-7-[(2,6-dimethylpiperidin-1-yl)methyl]-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid; SCHEMBL5770767; BDBM50332758
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[70] | |||
| Compound Name |
4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1H-pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL303891; SCHEMBL7779833; BDBM50289971; 4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-1H-pyrazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[100] | |||
| Compound Name |
2-(3,5-Dibromo-4-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42940; BDBM50057966
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-benzofuran
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL76376; BDBM50285515
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[101] | |||
| Compound Name |
2-(4-Chlorophenyl)-4-(methoxymethyl)-1-(4-methylsulfonylphenyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL46576; SCHEMBL3245726; BDBM50057910; 2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4-methoxymethyl-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
4-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-2-methyl-oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL419561; SCHEMBL5594315; BDBM50091211; 1-[4-(Methylsulfonyl)phenyl]-2-(2-methyloxazole-4-yl)-4-(trifluoromethyl)-1H-imidazole; 2-methyl-4-[1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]-1,3-oxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
4-(4-Methanesulfonyl-phenyl)-5,5-dimethyl-3-(pyridin-4-yloxy)-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL106255; SCHEMBL7487002; BDBM50082374; 5,5-dimethyl-4-(4-methylsulfonylphenyl)-3-pyridin-4-yloxyfuran-2-one; 3-(4-Pyridyloxy)-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[102] | |||
| Compound Name |
5-[4,5-Difluoro-2-[4-(methylsulfonyl)phenyl]phenyl]-1,3-benzodioxole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL416126; SCHEMBL6725632; BDBM50049635; 5-[4,5-difluoro-2-(4-methylsulfonylphenyl)phenyl]-1,3-benzodioxole; 5-(4,5-Difluoro-4''-methanesulfonyl-biphenyl-2-yl)-benzo[1,3]dioxole; 4-(Methylsulfonyl)-4',5'-difluoro-4'',5''-methylenedioxy-1,1':2',1''-terbenzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
3-(3-Fluorophenyl)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL126244; SCHEMBL6968964; BDBM50150188; 3-(3-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
5-Chloro-3-(4-methanesulfonyl-phenyl)-4''-methyl-[2,3'']bipyridinyl
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL92233; BDBM50072065
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[59] | |||
| Compound Name |
6-(3,4-Difluorophenyl)-5-(4-methylsulfonylphenyl)spiro[2.4]hept-5-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL92107; SCHEMBL8385002; BDBM50049013; 6-[4-(Methylsulfonyl)phenyl]-5-[3,4-difluorophenyl]spiro[2.4]hept-5-ene; 5-(3,4-Difluoro-phenyl)-6-(4-methanesulfonyl-phenyl)-spiro[2.4]hept-5-ene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[97] | |||
| Compound Name |
4-(5-Cyclohex-1-enyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL30091; SCHEMBL6352330; BDBM50057571; 4-[5-(cyclohexen-1-yl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
4-[5-(4-Hydroxy-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL282390; SCHEMBL6013946; BDBM50057523; ZINC28769523; 4-[3-(Trifluoromethyl)-5-(4-hydroxyphenyl)-1H-pyrazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
4-Amino-N-[3-(trifluoromethyl)phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL261520; 4-amino-n-[3-(trifluoromethyl)phenyl]benzenecarboxamide; 4-Amino-N-(3-(trifluoromethyl)phenyl)benzamide; (4-aminophenyl)-N-[3-(trifluoromethyl)phenyl]carboxamide; ARONIS023324; SCHEMBL11307930; CTK7D7155; DTXSID50373413; KS-00003P8D; ZINC2550025; 0039AF; BBL025906; BDBM50376384; MFCD00171039; SBB061794; STL062185; AKOS000111278; MCULE-5025667676; MS-6747; DB-016467; BB 0245770; FT-0714781; ST45052828; T8197; 4-Amino-N-(3-trifluoromethyl-phenyl)-benzam ide; (4-Aminophenyl)-N-(3-(trifluoromethyl)phenyl) formamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
6,8-Bis(trideuteriomethyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3355607; SCHEMBL16550581
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
2-Methyl-4-(4-fluorophenyl)-5-[4-(ethylsulfonyl)phenyl]oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL161377; BDBM50107525; 5-(4-Ethanesulfonyl-phenyl)-4-(4-fluoro-phenyl)-2-methyl-oxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[62] | |||
| Compound Name |
4-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]benzenemethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL109578; SCHEMBL8655486; BDBM50037949; ZINC13739715; [4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]phenyl]methanol; (4-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-yl}phenyl)methanol; {4-[2-(4-Methanesulfonyl-phenyl)-cyclopent-1-enyl]-phenyl}-methanol; 1-[2-(4-hydroxymethylphenyl)cyclopenten-1-yl]-4-(methylsulfonyl)benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
4-(5-Tert-butyl-3-phenyl-3,4-dihydropyrazol-2-yl)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3918115; SCHEMBL12494881; BDBM236653; US9388139, 22
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-[4-[5-Chloro-3-(4-sulfamoylphenyl)imidazol-4-yl]-2-fluorophenoxy]ethyl nitrate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL223529; BDBM50206933; 3-{4-[1-(4-(aminosulfonyl)phenyl)-4-chloro-1H-imidazol-5-yl]-2-fluorophenoxy}ethyl Nitrate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[96] | |||
| Compound Name |
4-(4-Cyclohexyl-2-methyl-oxazol-5-yl)-2-methyl-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL35783; BDBM50111003; 4-(4-cyclohexyl-2-methyl-1,3-oxazol-5-yl)-2-methylbenzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
4-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775092; BDBM50343905
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyrazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775097; BDBM50343910
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
5-Amino-N-[4-(trifluoromethyl)phenyl]pyridine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL260386; SCHEMBL13428723; BDBM50376378; AKOS019892491
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
N-Cyclohexyl-4-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL557874; SCHEMBL3748251; 2-Pyrimidinamine,N-cyclohexyl-4-[4-(methylsulfonyl)phenyl]-; BDBM50297657; SR-00000001867; SR-00000001867-1; N-cyclohexyl-4-(4-methylsulfonylphenyl)pyrimidin-2-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
(7-Tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-(4,5-dihydro-pyrazol-1-yl)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL326295; BDBM50066558
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[103] | |||
| Compound Name |
N-Benzyl-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551829; SCHEMBL5785800; BDBM50297677; N-benzyl-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine; 4-[4-(Methylsulfonyl)phenyl]-N-(phenylmethyl)-6-(trifluoromethyl)-2-pyrimidinamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2-(4-Chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-4-phenyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL298296; SCHEMBL213892; BDBM50057950; 2-(4-chlorophenyl)-1-(4-methylsulfonylphenyl)-4-phenylimidazole; 2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4-phenyl-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-thiophen-3-yl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL19056; BDBM50125630; 3-(3-Thienyl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
3-(3,4-Dichloro-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL125682; BDBM50150208
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
1-Chloro-4-[2-(4-methylsulfonylphenyl)-1-cyclopentenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL340573; SCHEMBL214545; ZINC18528; BDBM50029623; 1-[2-(4-chlorophenyl) cyclopenten-1-yl]-4-(methylsulfonyl)benzene; 1-[2-(4-Chlorophenyl)-1-cyclopentenyl]-4-(methylsulfonyl)benzene; 1-[2-(4-chlorophenyl)cyclopenten-1-yl]-4-methylsulfonylbenzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
(2R,3S,4S,5S,6S)-3,4,5-Trihydroxy-6-[4-[3-(4-methylsulfonylphenyl)-5-oxo-2H-furan-4-yl]phenoxy]oxane-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303697; BDBM50451154
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[104] | |||
| Compound Name |
6-Ethyl-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL187468; BDBM50153996
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
(S)-6-Chloro-7-isobutyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630252; SCHEMBL5645180; BDBM50332772; (2S)-6-chloro-7-(2-methylpropyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[70] | |||
| Compound Name |
N-Cyclohexyl-5-methyl-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL559812; BDBM50297660
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
{2-Chloro-4-[1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-phenyl}-methyl-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL416250; BDBM50057912
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
3,3-Dimethyl-5-[pyrrolizino(imino)methyl]-7-tert-butyl-2,3-dihydrobenzofuran
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL422075; BDBM50066562
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[103] | |||
| Compound Name |
2-(3,5-Dichlorophenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL45090; SCHEMBL5594692; BDBM50057982; 2-(3,5-Dichloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
US9271961, Bmt 4-90
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3945188; BDBM220124
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[105] | |||
| Compound Name |
2-(3-Methylsulfanylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL416989; SCHEMBL5594387; BDBM50057953; 1-(4-Methanesulfonyl-phenyl)-2-(3-methylsulfanyl-phenyl)-4-trifluoromethyl-1H-imidazole; 1-[4-(methylsulfonyl)phenyl]-2-[3-(methylthio)phenyl]-4-(trifluoromethyl)-1h-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
1-(4-Azido-phenyl)-5-p-tolyl-3-trifluoromethyl-1H-pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL104502; 1-(4-azidophenyl)-5-(4-methylphenyl)-3-(trifluoromethyl)pyrazole; BDBM50103509; 1-(4-Azidophenyl)-3-(trifluoromethyl)-5-(p-tolyl)-1H-pyrazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[106] | |||
| Compound Name |
4-(3-Methoxy-5-phenyl-pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL416394; SCHEMBL6341690; BDBM50057550; 4-(3-methoxy-5-phenylpyrazol-1-yl)benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
4-(4-(Methylsulfonyl)phenyl)-N-((tetrahydro-2H-pyran-4-yl)methyl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL563322; BDBM50297665
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[5] | |||
| Compound Name |
N-[6-(5-Methyl-thiazol-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43402; BDBM50073861
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
N-Methyl-N-(2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)phenyl)methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775111; BDBM50343924
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
6-Chloro-7-((isopropyl(methyl)amino)methyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630244; SCHEMBL5644537; BDBM50332755; 6-chloro-7-[[methyl(propan-2-yl)amino]methyl]-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[70] | |||
| Compound Name |
4-{4-Chloro-5-[3-fluoro-4-(2-hydroxyethoxy)phenyl]-1H-imidazol-1-yl}benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220113; BDBM50206930
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[96] | |||
| Compound Name |
4-(4-Fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-(phenylthio)pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL559422; BDBM50297707
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
4-[2-(4-Fluoro-phenyl)-pyrrol-1-yl]-N,N-dimethyl-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44421; BDBM50057896
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
N-(3-Aminopyridin-2-yl)-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL407577; BDBM50376380
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
4-[5-(3,4-Dimethoxyphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL282360; SCHEMBL6013938; BDBM50057607; 4-[3-(Trifluoromethyl)-5-(3,4-dimethoxyphenyl)-1H-pyrazole-1-yl]benzenesulfonamide; 4-[5-(3,4-Dimethoxy-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
1-Allyl-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1H-pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL302527; SCHEMBL8632132; BDBM50289972
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[100] | |||
| Compound Name |
N-(4-Amino-2-pyridyl)-4-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL261550; SCHEMBL13428724; BDBM50376379
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
2-(4-Pyridinyl)-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL16952; SCHEMBL7841916; BDBM50076864; 4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-2-pyridin-4-yl-1,3-thiazole; 4-[4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazol-2-yl]-pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(3,4-dimethylphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3823814; BDBM50185921
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[48] | |||
| Compound Name |
1-(7-Cyclopentyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-4-cyclopropyl-butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL279550; SCHEMBL4613981; BDBM50063794; 1-(7-cyclopentyl-3,3-dimethyl-2H-1-benzofuran-5-yl)-4-cyclopropylbutan-1-one; 1-[(2,3-Dihydro-3,3-dimethyl-7-cyclopentylbenzofuran)-5-yl]-4-cyclopropyl-1-butanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[107] | |||
| Compound Name |
1-(4-Methanesulfonylphenyl)-3-[(3,4-dimethoxy)phenoxymethyl]-5-phenyl-1H-pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL375309; BDBM50156583
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
3-[4-(Trifluoromethyl)phenyl]-4-(4-sulfamoylphenyl)-4-oxazoline-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL304810; SCHEMBL8073069; BDBM50084371; 4-[2-oxo-3-[4-(trifluoromethyl)phenyl]-1,3-oxazol-4-yl]benzenesulfonamide; 4-[2-Oxo-3-(4-trifluoromethyl-phenyl)-2,3-dihydro-oxazol-4-yl]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[108] | |||
| Compound Name |
6-[4-(Methylsulfonyl)phenyl]-5-[3-fluoro-4-methoxyphenyl]spiro[2.4]hept-5-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL88550; SCHEMBL8384169; BDBM50049035; 5-(3-Fluoro-4-methoxy-phenyl)-6-(4-methanesulfonyl-phenyl)-spiro[2.4]hept-5-ene; 6-(3-fluoro-4-methoxyphenyl)-5-(4-methylsulfonylphenyl)spiro[2.4]hept-5-ene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[97] | |||
| Compound Name |
5-Cycloheptylidenemethyl-6-(4-methanesulfonyl-phenyl)-benzo[1,3]dioxole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL357315; SCHEMBL5723382; BDBM50136108
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[61] | |||
| Compound Name |
(2S)-6-Chloro-5,7-bis(trideuteriomethyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3355611; SCHEMBL19097647
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
4-[2-(3,5-Dichloro-4-methoxyphenyl)-4,5-difluorophenyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL300597; SCHEMBL6721457; BDBM50049621; 3'',5''-Dichloro-4''-methoxy-4',5'-difluoro-1,1':2',1''-terbenzene-4-sulfonamide; 3,5-Dichloro-4'',5''-difluoro-4-methoxy-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
2-Methyl-4-[4-(methylsulfonyl)phenyl]-5-(4-fluorophenyl)oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL348348; SCHEMBL7503718; BDBM50107518; 5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-2-methyl-oxazole; 5-(4-fluorophenyl)-2-methyl-4-(4-methylsulfonylphenyl)-1,3-oxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[62] | |||
| Compound Name |
2-(4-Methanesulfonyl-phenyl)-6-methyl-3-(4-trifluoromethoxy-phenoxy)-pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127560; BDBM50150221
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
3-Morpholin-4-ylpropyl 3-(5-chlorofuran-2-yl)-4-phenyl-1,2-oxazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380872; SCHEMBL12374634; BDBM50491540
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[89] | |||
| Compound Name |
2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-spiro[4.5]dec-2-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328146; BDBM50049012
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
Sodium;acetyl-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonylazanide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42077
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[109] | |||
| Compound Name |
4-[3-(2-Chlorophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410347; BDBM50074905
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
1,2-Difluoro-4-(4-methoxy-3-methylphenyl)-5-(4-methylsulfonylphenyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL418448; SCHEMBL6728864; BDBM50049636; 1,2-difluoro-4-(4-methoxy-3-methylpheny)-5-[4-(methylsulfonyl)phenyl]benzene; 3''-Methyl-4',5'-difluoro-4''-methoxy-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 4'',5''-Difluoro-4''''-methanesulfonyl-4-methoxy-3-methyl-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
8-Fluoro-1-(4-methanesulfonyl-phenyl)-7-methoxy-3-trifluoromethyl-1,5-dihydro-isothiochromeno[4,3-c]pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL96110; BDBM50288326
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[93] | |||
| Compound Name |
1-[2-(4-Methylsulfonylphenyl)-1-cyclopentenyl]-4-trifluoromethylbenzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL109030; SCHEMBL215443; BDBM50029610; 1-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]-4-(trifluoromethyl)benzene; 1-(methylsulfonyl)-4-{2-[4-(trifluoromethyl)phenyl]cyclopent-1-en-1-yl}benzene; 1-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]-4-(trifluoromethyl)benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
Ethyl 2-[4-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)-5-(trifluoromethyl)pyrazol-1-yl]acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL65793; ethyl[4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]acetate; ethyl[4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazol-1-yl]acetate; SCHEMBL8288067; BDBM50289970; ethyl [4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazol-1-yl]acetate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[100] | |||
| Compound Name |
2-(4-Methanesulfonyl-phenyl)-6-methyl-3-phenoxy-pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127125; SCHEMBL1376131; BDBM50150199; 6-methyl-2-(4-methylsulfonylphenyl)-3-phenoxypyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
Unii-3G75T52B7D
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL268470; 3G75T52B7D; 6'-Carboxy etoricoxib; 6'-Carboxy-etoricoxib; 6?Desmethyl-6?carboxy etoricoxib; 6'-Desmethyl-6'-carboxy Etoricoxib; BDBM50098999; DS-015700; 3-(4-Mesylphenyl)-5-chloro-2,3'-bipyridine-6'-carboxylic acid; 5-Chloro-3-(4-(methylsulfonyl)phenyl)(2,3'-bipyridine)-6'-carboxylic acid; (2,3'-Bipyridine)-6'-carboxylic acid, 5-chloro-3-(4-(methylsulfonyl)phenyl)-; 5-[5-chloro-3-(4-methylsulfonylphenyl)pyridin-2-yl]pyridine-2-carboxylic acid; 5-Chloro-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridine]-6'-carboxylic acid; 5-Chloro-3-(4-methanesulfonyl-phenyl)-[2,3'']bipyridinyl-6''-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[110] | |||
| Compound Name |
2-(4-Methanesulfonyl-phenyl)-6-methyl-3-m-tolyloxy-pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL126404; SCHEMBL5100469; 6-methyl-3-(3-methylphenoxy)-2-(4-methylsulfonylphenyl)pyran-4-one; BDBM50150220
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
4-[3-(4-Methoxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ML141; ML 141; ML-141; CID-2950007; MLS000693334; MLS002699035; KUC103352N-2; SMR000299863; 4-[5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]benzenesulfonamide; 4-[4,5-dihydro-5-(4-methoxyphenyl)-3-phenyl-1H-pyrazol-1-yl]-benzenesulfonamide; 4-(5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonamide; MLS006011906; CHEMBL1370630; SCHEMBL12494043; BDBM43220; cid_2950007; AOB1515; HMS2688G07; KUC103352N; BCP13193; EX-A1165; 2551AH; KSC-6-125; MFCD05987165; s7686; SBB085162; STL259581; AKOS000296683; AKOS022118974; KUC103352N-03; CCG-268734; CS-3940; KSC-23-233; MCULE-5226073572; CID 2950007; NCGC00263209-01; NCGC00263209-02; NCGC00263209-09; AC-33173; AK205799; AS-16658; HY-12755; ML 141, >=98% (HPLC); UNM-0000305822; UNM-0000305868; UNM-0000306066; US9388139, 11; SR-01000271680; SR-01000271680-1; Q27163444; 4-[5-(4-methoxyphenyl)-3-phenyl-2-pyrazolinyl]benzenesulfonamide; 4-[5-(4-methoxyphenyl)-3-phenyl-2-pyrazolin-1-yl]benzenesulfonamide; 4-(5-(4-methoxyphenyl)-3-phenyl-4,5-dihydro-1Hpyrazol-1-yl)benzenesulfonamide; 4-[4,5-Dihydro-5-(4-methoxyphenyl)-3-phenyl-1H-pyrazol-1-yl]benzenesulfonamide; 4-[5-(4-METHOXYPHENYL)-3-PHENYL-4,5-DIHYDROPYRAZOL-1-YL]BENZENESULFONAMIDE
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-(4-Fluorophenyl)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL338705; SCHEMBL1377265; BDBM50150216; 3-(4-fluorophenyl)-2-(4-methanesulfonylphenyl)-6-methylpyran-4-one; 3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
4-[5-Tert-butyl-3-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3910060; SCHEMBL12494514; BDBM236652; US9388139, 21
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43165; SCHEMBL5698694; BDBM50286951; 5-(4-fluorophenyl)-4-(4-methylsulfonylphenyl)-1H-imidazole; 5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
2-(2-Hydroxy-2-methylpropoxy)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL49319; SCHEMBL6658868; BDBM50078590; 1-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-pyridin-2-yloxy]-2-methyl-propan-2-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[81] | |||
| Compound Name |
5-Methyl-4-phenyl-3-(2,4,6-trimethoxy-phenyl)-isoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL186764; BDBM50153044; ZINC13583266
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[94] | |||
| Compound Name |
[3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-1H-indol-2-yl]-methanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL184022; SCHEMBL5114746; BDBM50151784; [3-(4-fluorophenyl)sulfanyl-6-methylsulfonyl-1H-indol-2-yl]methanol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[54] | |||
| Compound Name |
5-Hydroxy-3-(4-isopropyl-phenyl)-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL18867; BDBM50125615; 3-(4-Isopropylphenyl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(3-chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3823208; BDBM50185930
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[48] | |||
| Compound Name |
4-[3-(3-Bromophenyl)-5-tert-butyl-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3960150; SCHEMBL12524149; BDBM236647; US9388139, 16
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
(2RS,4R)-2-(1-phenyl-3-p-tolyl-1H-pyrazol-4-yl)thiazolidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1631310; BDBM50332956
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[87] | |||
| Compound Name |
1-(4-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole-3-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43366; SCHEMBL7216750; BDBM50057895; 1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrole-3-carbonitrile; 1-(4-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole-3-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
(5R)-3-Isopropoxy-4-[4-(methylsulfonyl)phenyl]-5beta-ethyl-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL111904; SCHEMBL5279425; BDBM50120571
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[83] | |||
| Compound Name |
Phenylmethyl 2-{4-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL237402; BDBM50226658; benzyl 2-[4-chloro-1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[111] | |||
| Compound Name |
N-Cyclohexyl-5-methyl-4-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL560285; SCHEMBL5022015; BDBM50297658
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
6-[4-(Methylsulfonyl)phenyl]-5-[3-bromo-4-methoxyphenyl]spiro[2.4]hept-5-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL86363; SCHEMBL8384083; BDBM50049032; 5-(3-Bromo-4-methoxy-phenyl)-6-(4-methanesulfonyl-phenyl)-spiro[2.4]hept-5-ene; 6-(3-bromo-4-methoxyphenyl)-5-(4-methylsulfonylphenyl)spiro[2.4]hept-5-ene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[97] | |||
| Compound Name |
4-[3-Difluoromethyl-5-(5-methyl-furan-2-yl)-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29847; SCHEMBL6341960; BDBM50057612; 4-[3-(difluoromethyl)-5-(5-methylfuran-2-yl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
3-(2,4-Dichloro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL18254; BDBM50125617; 3-(2,4-Dichlorophenyl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
4-Chloro-5-(4-chlorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL28545; SCHEMBL6339325; BDBM50057585; 4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl)-1H-pyrazole-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
2-(3-Methoxyphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44468; SCHEMBL5594045; BDBM50057940; 1-(4-Methanesulfonyl-phenyl)-2-(3-methoxy-phenyl)-4-trifluoromethyl-1H-imidazole; 1-[4-(Methylsulfonyl)phenyl]-2-(3-methoxyphenyl)-4-(trifluoromethyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
1,2-Difluoro-4-(4-fluoro-3-methylphenyl)-5-[4-(methylsulfonyl)phenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL443791; SCHEMBL6721702; ZINC3814664; BDBM50049623; 1,2-difluoro-4-(4-fluoro-3-methylphenyl)-5-(4-methylsulfonylphenyl)benzene; 3''-Methyl-4',4'',5'-trifluoro-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 4,4'',5''-Trifluoro-4''''-methanesulfonyl-3-methyl-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
N-(3-Phenylsulfonyl-4-pyridinyl)trifluoromethanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL224201; CTK3D2864; DTXSID00464229; BDBM50158448; Methanesulfonamide, 1,1,1-trifluoro-N-[3-(phenylsulfonyl)-4-pyridinyl]-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[112] | |||
| Compound Name |
4-(Trifluoromethyl)-13lambda6-thia-5,7,19-triazatricyclo[12.2.2.12,6]nonadeca-1(17),2,4,6(19),14(18),15-hexaene 13,13-dioxide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL563262; BDBM50297663
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
1-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-4-methyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43270; BDBM50057985
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-Methyl-4-phenyl-5-[4-(methylsulfonyl)phenyl]oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL350549; BDBM50107516; 5-(4-Methanesulfonyl-phenyl)-2-methyl-4-phenyl-oxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[62] | |||
| Compound Name |
1,2-Bis(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL296515; SCHEMBL5594093; BDBM50057935; 1,2-Bis-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole; 1-[4-(Methylsulfonyl)phenyl]-2-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
1-[1-[(2-Chlorophenyl)methyl]-2-oxopyridin-3-yl]-3-(3-ethylphenyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1271476; BDBM50417192
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[113] | |||
| Compound Name |
(2S)-6-Chloro-8-methyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3355613; SCHEMBL5168838; CHEMBL3545847; BDBM50030828
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
4-Methyl-3-[1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL320986; SCHEMBL5593921; BDBM50091186; 3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-4-methyl-pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
3-(2,4-Difluorophenyl)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL126810; SCHEMBL1377412; BDBM50150204; 3-(2,4-Difluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one; 3-(2,4-difluorophenyl)-2-(4-methanesulfonylphenyl)-6-methylpyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-N-methyl-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL30200; SCHEMBL5070999; BDBM50057576; 4-[5-(4-fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]-N-methylbenzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
2-Methyl-4-[4-(methylsulfonyl)phenyl]-5-(4-fluorophenyl)thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL274473; SCHEMBL213779; 5-(4-fluorophenyl)-2-methyl-4-(4-methylsulfonylphenyl)-1,3-thiazole; BDBM50076857; 5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-2-methyl-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
1-Methylsulfanyl-4-[2-(4-methylsulfonylphenyl)-1-cyclopentenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL111039; SCHEMBL212242; ZINC3814641; BDBM50037946; 1-(methylsulfonyl)-4-{2-[4-(methylthio)phenyl]cyclopent-1-en-1-yl}benzene; 1-[2-(4-methylthiophenyl)cyclopenten-1-yl)-4-(methylsulfonyl)benzene; 1-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]-4-(methylthio)benzene; 1-methylsulfanyl-4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
6-Chloro-7-((ethyl(methyl)amino)methyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630243; 6-chloro-7-[[ethyl(methyl)amino]methyl]-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid; SCHEMBL14440867; BDBM50332754
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[70] | |||
| Compound Name |
3-(3-Acetoxyphenyl)-4-[4-(methylsulfonyl)phenyl]-2,5-dihydrofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL93024; BDBM50118684; Acetic acid 3-[4-(4-methanesulfonyl-phenyl)-2-oxo-2,5-dihydro-furan-3-yl]-phenyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[114] | |||
| Compound Name |
Ethyl 2-(4-chlorophenyl)-1-(4-methylsulfonylphenyl)imidazole-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL289484; SCHEMBL5594811; BDBM50057964; Ethyl [2-(4-chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl] carboxylate; Ethyl [2-(4-chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]carboxylate; 2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole-4-carboxylic acid ethyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
3-[5-Tert-butyl-3-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3931444; SCHEMBL12523616; BDBM236639; US9388139, 6
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-(Methylsulfonyl)-N-(2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)phenyl)methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775108; BDBM50343921
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
[3-(5-Chlorofuran-2-yl)-4-phenylisoxazol-5-yl]carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380868; SCHEMBL2279481; BDBM50491532; [3-(5chlorofuran-2-yl)-4-phenylisoxazol-5-yl]carboxylic acid; 3-(5-chlorofuran-2-yl)-4-phenyl-1,2-oxazole-5-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[89] | |||
| Compound Name |
2-(3-Bromophenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43616; SCHEMBL5594639; BDBM50057926; 1-[4-(Methylsulfonyl)phenyl]-2-(3-bromophenyl)-4-(trifluoromethyl)-1H-imidazole; 2-(3-Bromo-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
N'-[4-[4-[(Z)-[(Z)-[3-(4-Chlorophenyl)-4-oxo-1,3-thiazolidin-2-ylidene]hydrazinylidene]methyl]-3-phenylpyrazol-1-yl]phenyl]sulfonyl-N,N-dimethylmethanimidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL467837; BDBM50292563
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[84] | |||
| Compound Name |
2-[4-(Methylsulfonyl)phenyl]-3-(4-fluorophenyl)pyrazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55189; BDBM50049655; ZINC29546343; 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
1-Methoxymethyl-4-[2-(4-methylsulfonylphenyl)-1-cyclopentenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL109486; SCHEMBL8652283; BDBM50037947; ZINC13739716; 1-(methoxymethyl)-4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzene; 1-[2-(4-methoxymethyl phenyl)cyclopenten-1-yl]-4 -(methylsulfonyl)benzene; 1-[2-(4-methoxymethyl phenyl)cyclopenten-1-yl]-4-(methylsulfonyl)benzene; 1-[2-(4-methoxymethylphenyl)cyclopenten-1-yl]-4-(methylsulfonyl)benzene; 1-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]-4-(methoxymethyl)benzene; 1-(methoxymethyl)-4-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-yl}benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
3-(4-Bromophenyl)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL338927; SCHEMBL5708933; BDBM50150186; 3-(4-Bromo-phenyl)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-(2-Chlorophenyl)-4-(2-thienyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17069; SCHEMBL7842779; BDBM50076855; 2-(2-Chloro-phenyl)-5-(4-methanesulfonyl-phenyl)-4-thiophen-2-yl-thiazole; 2-(2-chlorophenyl)-5-(4-methylsulfonylphenyl)-4-thiophen-2-yl-1,3-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL171360; SCHEMBL5684836; BDBM50286950
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
N-[6-(3,5-Dichloro-pyridin-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL290739; BDBM50073863; N-[6-(3,5-dichloropyridin-2-yl)sulfanyl-1-oxo-2,3-dihydroinden-5-yl]methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(2-fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3823187; BDBM50185951
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[48] | |||
| Compound Name |
1-Allyl-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-5-trifluoromethyl-1H-pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL66856; SCHEMBL251700; BDBM50289977; 4-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)-1-prop-2-enyl-5-(trifluoromethyl)pyrazole; 1-allyl-4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[100] | |||
| Compound Name |
N-[6-(4-Methyl-thiazol-2-ylsulfanyl)-1-oxo-1,3-dihydro-isobenzofuran-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43520; SCHEMBL8596791; BDBM50073862
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
4-[5-Tert-butyl-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3918044; SCHEMBL12493371; BDBM236634; US9388139, 1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
4-Amino-N-[2-(trifluoromethyl)phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL261321; CTK7D7167; ZINC7468092; BDBM50376385; AKOS000159287
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
4-[3-(2,4-Dichlorophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410353; BDBM50074911
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
6-Chloro-8-(4-(methylsulfonamido)phenyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1669028; SCHEMBL5768710; BDBM50336007; 6-chloro-8-[4-(methanesulfonamido)phenyl]-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[75] | |||
| Compound Name |
2-(4-Chlorophenyl)-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL277116; SCHEMBL7844918; BDBM50076858; 2-(4-Chloro-phenyl)-4-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
4-[2-(3-Fluoro-5-methoxy-phenyl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43089; SCHEMBL5594782; BDBM50057995; 4-[2-(3-fluoro-5-methoxyphenyl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-(4-Fluoro-phenyl)-1-(3-methanesulfonyl-phenyl)-1H-pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL288570; BDBM50057865
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
2-[3-(Methoxymethyl)phenyl]-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL295707; SCHEMBL5594426; BDBM50057937; 1-(4-Methanesulfonyl-phenyl)-2-(3-methoxymethyl-phenyl)-4-trifluoromethyl-1H-imidazole; 1-[4-(Methylsulfonyl)phenyl]-2-[3-(methoxymethyl)phenyl]-4-(trifluoromethyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
5-Cyclohexylidenemethyl-6-(4-methanesulfonyl-phenyl)-benzo[1,3]dioxole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL347720; SCHEMBL5723251; BDBM50136109
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[61] | |||
| Compound Name |
4-[3-(5-Chloro-furan-2-yl)-5-methyl-isoxazol-4-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL185639; BDBM50153041
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[94] | |||
| Compound Name |
2-(2-Fluoro-biphenyl-4-yl)-2-methyl-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL380853; SCHEMBL3938352; BDBM50181914; 2-(3-fluoro-4-phenylphenyl)-2-methylpropanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[115] | |||
| Compound Name |
1-(3-Chloro-4-methanesulfonyl-phenyl)-2-(4-fluoro-phenyl)-1H-pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44367; BDBM50057881
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
N-[6-(4-Ethyl-thiazol-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL289731; BDBM50073869
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
4-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]benzonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL338105; SCHEMBL8652231; BDBM50037948; ZINC13739714; 4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzonitrile; 4-[2-(4-Methanesulfonyl-phenyl)-cyclopent-1-enyl]-benzonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
2-(4-Methanesulfonyl-phenyl)-6-methyl-3-naphthalen-2-yl-pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339817; SCHEMBL6972159; BDBM50150209; 6-methyl-2-(4-methylsulfonylphenyl)-3-naphthalen-2-ylpyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
(S)-6,8-Dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288697; SCHEMBL5171314; BDBM50331073; (2s)-6,8-dimethyl-2-(trifluoromethyl)-2h-chromene-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[68] | |||
| Compound Name |
4-[2-[3-(Trifluoromethyl)-4-fluorophenyl]-1-cyclopentenyl]-1-(methylsulfonyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL423004; SCHEMBL8652854; BDBM50029597; 1-Fluoro-4-[2-(4-methanesulfonyl-phenyl)-cyclopent-1-enyl]-2-trifluoromethyl-benzene; 1-fluoro-4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]-2-(trifluoromethyl)benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[73] | |||
| Compound Name |
N-[6-(3-Chloro-pyridin-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41739; BDBM50073865; N-[6-(3-chloropyridin-2-yl)sulfanyl-1-oxo-2,3-dihydroinden-5-yl]methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
1-(2-(4-(2-(Methylsulfonyl)phenoxy)phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775093; BDBM50343906
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
4-(4-(Methylsulfonyl)phenyl)-N-p-tolyl-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL560887; BDBM50297679
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
1-(4-Methanesulfonyl-phenyl)-2-pyridin-3-yl-1H-imidazole-4-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL320318; SCHEMBL5594223; BDBM50091193; 1-(4-methylsulfonylphenyl)-2-pyridin-3-ylimidazole-4-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
N-[6-(4-Methylsulfanyl-thiazol-2-ylsulfanyl)-1-oxo-1,3-dihydro-isobenzofuran-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL434014; BDBM50073860
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
2-Chloro-1-fluoro-4-[2-(4-methylsulfonylphenyl)phenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL52454; SCHEMBL6721461; CTK0A7284; DTXSID00445553; BDBM50049630; ZINC13755782; 1,1':2',1''-Terphenyl, 3-chloro-4-fluoro-4''-(methylsulfonyl)-; 2-chloro-1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]phenyl]benzene; 3''-Chloro-4''-fluoro-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 3-Chloro-4-fluoro-4''''-methanesulfonyl-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
4-[5-Tert-butyl-3-(4-nitrophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3914590; SCHEMBL12494570; BDBM236635; US9388139, 2
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
5-[2-(4-Methanesulfonyl-phenyl)-cyclopent-1-enyl]-benzo[1,3]dioxole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL405623; SCHEMBL8654540; ZINC3814648; BDBM50029606; 5-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]-1,3-benzodioxole; 4-[2-(3,4-Methylenedioxyphenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene; 5-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-yl}-1,3-benzodioxole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[73] | |||
| Compound Name |
1,2-Difluoro-4-(4-methylphenyl)-5-(4-methylsulfonylphenyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL293771; SCHEMBL6721737; ZINC3814669; BDBM50049660; 4-Mesyl-4',5'-difluoro-4''-methyl-1,1':2',1''-terbenzene; 1,2-difluoro-4-(4-methylphenyl)-5-[4-(methylsulfonyl)phenyl]benzene; 4'',5''-Difluoro-4''''-methanesulfonyl-4-methyl-[1,1'';2'',1'''']terphenyl; 4'',5''-Difluoro-4-methanesulfonyl-4''''-methyl-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
1,2,3,4-Tetrafluoro-5-(4-fluorophenyl)-6-(4-methylsulfonylphenyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL54367; SCHEMBL6724517; BDBM50049627; ZINC29544871; 3',4',4'',5',6'-Pentafluoro-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 4,3'',4'',5'',6''-Pentafluoro-4''''-methanesulfonyl-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
4-[5-(2-Methoxyphenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3927064; SCHEMBL12495092; BDBM236640; US9388139, 8
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
1-(4-Methanesulfonylphenyl)-3-[(3-nitro)phenoxymethyl]-5-phenyl-1H-pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL222531; BDBM50156591
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-Benzyl-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL562768; BDBM50297702
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
4-[5-(3-Methoxyphenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3912685; SCHEMBL12496095; BDBM236641; US9388139, 9
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
1-(4-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43002; 1-(4-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole; 1-(4-Fluorophenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrole; 1-(4-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl)-1H-pyrrole; Oprea1_077682; SCHEMBL5309102; ZINC22442; KS-00002Y1U; BDBM50057904; AKOS005075537; MCULE-5886645321; 10M-338S; 1-(4-fluorophenyl)-2-(4-methanesulfonylphenyl)-5-methyl-1H-pyrrole; 1-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole; 1-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-5-methyl-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
1-(4-Methylsulfonylphenyl)-2-thiophen-2-yl-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL421417; 2-[1-(4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1H-imidazol-2-yl]thiophene; 2-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1h-imidazol-2-yl]thiophene; SCHEMBL3247760; BDBM50091182; 1-(4-Methanesulfonyl-phenyl)-2-thiophen-2-yl-4-trifluoromethyl-1H-imidazole; 1-[4-(Methylsulfonyl)phenyl]-2-(2-thienyl)-4-(trifluoromethyl)-1H-imidazole; 2-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl) -1h-imidazol-2-yl]thiophene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
2,3-Dimethyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]-4-isoxazoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL322240; BDBM50103314; 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2,3-dimethyl-2,3-dihydro-isoxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[116] | |||
| Compound Name |
1-(4-Fluoro-benzyl)-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL288773; BDBM50057879
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
4-[5-Tert-butyl-3-(2-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3909725; SCHEMBL12524151; BDBM236648; US9388139, 17
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
1,2-Dichloro-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL54945; SCHEMBL6724098; BDBM50049654; ZINC13755788; 1,2-dichloro-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]benzene; 4',5'-Dichloro-4''-fluoro-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 4'',5''-Dichloro-4''''-fluoro-4-methanesulfonyl-[1,1'';2'',1'''']terphenyl; 4'',5''-Dichloro-4-fluoro-4''''-methanesulfonyl-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
3-Methoxy-5-[1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL320118; SCHEMBL5594195; BDBM50091191; 3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-5-methoxy-pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
4-[2-(3-Fluoro-4-methoxyphenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL111314; SCHEMBL8655413; ZINC3814647; BDBM50029602; 2-fluoro-1-methoxy-4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzene; 2-fluoro-1-methoxy-4-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-yl}benzene; 2-Fluoro-4-[2-(4-methanesulfonyl-phenyl)-cyclopent-1-enyl]-1-methoxy-benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[73] | |||
| Compound Name |
2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-spiro[4.4]non-2-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL327900; SCHEMBL8385085; BDBM50049039; 2-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)spiro[4.4]non-2-ene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
3-[3-(Pentafluoro-lambda6-sulfanyl)anilino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623736; BDBM50124576
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[117] | |||
| Compound Name |
2-(4-Chlorophenyl)-4-methyl-1-(4-(methylsulfonyl)phenyl)-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL46761; 2-(4-chlorophenyl)-1-(4-(methylsulfonyl)phenyl]-4-methyl-1H-imidazole; 2-(4-chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-4-methyl-1H-imidazole; SCHEMBL212832; CTK0E3584; DTXSID70433205; 2-(4-chlorophenyl)-4-methyl-1-(4-methylsulfonylphenyl)imidazole; ZINC3814600; BDBM50057932; NSC740031; NSC-740031; 1-[4-(Methylsulfonyl)phenyl]-2-(4-chlorophenyl)-4-methyl-1H-imidazole; 1H-Imidazole, 2-(4-chlorophenyl)-4-methyl-1-[4-(methylsulfonyl)phenyl]-; 2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4-methyl-1H-imidazole; 2-(4-chlorophenyl)-4-methyl-1-(4-(methylsulfonyl)phenyl)-1H- imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-Benzyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17276; SCHEMBL7839801; BDBM50076874; 2-Benzyl-4-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazole; 2-benzyl-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-1,3-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
2-[4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-5-trifluoromethyl-pyrazol-1-yl]-N-phenyl-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL67721; SCHEMBL251667; BDBM50289973; 2-[4-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)-5-(trifluoromethyl)pyrazol-1-yl]-N-phenylacetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[100] | |||
| Compound Name |
2-Amino-4-(4-cyclohexyl-2-methyl-oxazol-5-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL416589; BDBM50110996
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2-(4-Methanesulfonyl-phenyl)-6-methyl-3-(4-trifluoromethyl-phenoxy)-pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339258; BDBM50150190
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
1-(4-Methanesulfonyl-phenyl)-2-(2-methoxy-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL45139; BDBM50057909
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL359787; BDBM50153985
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
2-(2-Fluorophenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43645; SCHEMBL5594615; BDBM50057915; 2-(2-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-{[2-Nitro-5-(trifluoromethyl)phenyl]amino}benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3899044; CTK8I5600; BDBM220123; ZINC39123565; US9271961, BMT 5-119
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[105] | |||
| Compound Name |
3-(3-Fluoro-4-methoxy-phenyl)-2-(4-methanesulfonyl-phenyl)-benzofuran
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL312221; SCHEMBL5698505; BDBM50285520; 3-(3-fluoro-4-methoxyphenyl)-2-(4-methylsulfonylphenyl)-1-benzofuran
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[101] | |||
| Compound Name |
3-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-1H-indene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL80047; BDBM50285516
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[101] | |||
| Compound Name |
6-Bromo-8-methyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3342570; SCHEMBL5647446; BDBM50030830
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
1-[2-(3-Chloro-4-fluorophenyl)cyclopenten-1-yl]-4-(methylsulfonyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL322949; SCHEMBL8655051; BDBM50029598; ZINC13744268; 2-chloro-1-fluoro-4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzene; 4-[2-(3-Chloro-4-fluorophenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene; 2-Chloro-1-fluoro-4-[2-(4-methanesulfonyl-phenyl)-cyclopent-1-enyl]-benzene; 2-chloro-1-fluoro-4-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-yl}benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[73] | |||
| Compound Name |
6-Methoxy-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288537; BDBM50331053
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[68] | |||
| Compound Name |
N-[1-Oxo-6-(pyridin-2-ylsulfanyl)-indan-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL35992; SCHEMBL5347123; BDBM50048220; ZINC13744818; N-(1-oxo-6-pyridin-2-ylsulfanyl-2,3-dihydroinden-5-yl)methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
4-[5-Tert-butyl-2-(4-carboxyphenyl)-3,4-dihydropyrazol-3-yl]-3-methoxybenzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3909240; BDBM236637; US9388139, 4
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
3-(2-Fluorophenyl)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL126392; SCHEMBL5708905; BDBM50150207; 3-(2-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
4-[2-(3,4-Dichlorophenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL111597; SCHEMBL8651364; BDBM50029609; ZINC13744274; 1,2-dichloro-4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzene; 1,2-Dichloro-4-[2-(4-methanesulfonyl-phenyl)-cyclopent-1-enyl]-benzene; 1,2-dichloro-4-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-yl}benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[73] | |||
| Compound Name |
4-(3-Fluoromethyl-5-phenyl-pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL285335; SCHEMBL6342006; BDBM50057559; 4-[3-(fluoromethyl)-5-phenylpyrazol-1-yl]benzenesulfonamide; 4-[3-fluoromethyl-5-phenyl-1H-pyrazol-1-yl]benzenesulfonamide; 4-[3-fluoromethyl-5-phenyl-1h-pyrazol1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
6-Chloro-5-ethoxy-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630235; SCHEMBL5645914; BDBM50332747
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[70] | |||
| Compound Name |
4-[5-(2,5-Dichlorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL286256; SCHEMBL5674345; BDBM50057615; 4-[5-(2,5-Dichloro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
6,8-Dibromo-5,7-bis(trideuteriomethyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3355604; SCHEMBL16550570
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
3-[1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1H-pyrrol-2-yl]-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL298231; BDBM50057885
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
N-[1-Oxo-6-(4-vinyl-thiazol-2-ylsulfanyl)-1,3-dihydro-isobenzofuran-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL41405; BDBM50073864
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
(R)-2-[4-((1S,2R)-2-Hydroxy-cyclopentylmethyl)-phenyl]-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL18883; BDBM50140318
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[42] | |||
| Compound Name |
1-[4,4-Diethyl-2-(4-methylsulfonylphenyl)-1-cyclopentenyl]-4-fluorobenzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL129215; SCHEMBL8655495; BDBM50037944; 1-[4,4-diethyl-2-(4-methylsulfonylphenyl)cyclopenten-1-yl]-4-fluorobenzene; 1-Fluoro-4-[2-[4-(methylsulfonyl)phenyl]-4,4-diethyl-1-cyclopentenyl]benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
1-(4-Methylsulfonylphenyl)-4-(trifluoromethyl)-2-[3-(trifluoromethyl)phenyl]imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42094; SCHEMBL5594618; BDBM50057955; 1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-2-(3-trifluoromethyl-phenyl)-1H-imidazole; 1-[4-(methylsulfonyl)phenyl]-2-[3-(trifluoromethyl)phenyl]-4-(trifluoromethyl)-1h-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
1,2-Difluoro-4-(3-fluoro-4-methoxyphenyl)-5-[4-(methylsulfonyl)phenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL54649; SCHEMBL6724312; BDBM50049634; ZINC13755790; 1,2-difluoro-4-(3-fluoro-4-methoxyphenyl)-5-(4-methylsulfonylphenyl)benzene; 3,4'',5''-Trifluoro-4''''-methanesulfonyl-4-methoxy-[1,1'';2'',1'''']terphenyl; 4''-Methoxy-3'',4',5'-trifluoro-4-(methylsulfonyl)-1,1':2',1''-terbenzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
6-(4,5-Difluoro-4''-methanesulfonyl-biphenyl-2-yl)-2,3-dihydro-benzo[1,4]dioxine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL54746; BDBM50049624; 4-(Methylsulfonyl)-4',5'-difluoro-4'',5''-ethylenedioxy-1,1':2',1''-terbenzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
3-(4-Methoxyphenyl)-2-(4-(methylsulfonyl)phenyl)thiazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400080; BDBM50221107
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[51] | |||
| Compound Name |
4-[5-(4-Nitrophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL28664; NAS-23; SCHEMBL6013922; CTK5I3101; BDBM50057574; 4-[5-(4-Nitro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide; 4-(5-(4-nitrophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
1-[4-(Methylsulfonyl)phenyl]-2-[3-(dimethylamino)-4-chlorophenyl]-4-(trifluoromethyl)-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42174; BDBM50057960; {2-Chloro-5-[1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-phenyl}-dimethyl-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
1-(3-Chloro-4-methoxyphenyl)-4,5-difluoro-2-[4-(methylsulfonyl)phenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL52019; SCHEMBL6725713; BDBM50049641; 1-(3-chloro-4-methoxyphenyl)-4,5-difluoro-2-(4-methylsulfonylphenyl)benzene; 3''-Chloro-4',5'-difluoro-4''-methoxy-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 3-Chloro-4'',5''-difluoro-4''''-methanesulfonyl-4-methoxy-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
2-(3,5-Dichloro-4-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42408; SCHEMBL5594108; BDBM50057998; 2-(3,5-dichloro-4-methoxyphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-(3-Fluoro-4-methyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42180; SCHEMBL5593912; BDBM50057978; 2-(3-fluoro-4-methylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
6-[4-(Methylsulfonyl)phenyl]-5-[4-(trifluoromethoxy)phenyl]spiro[2.4]hept-5-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL89263; SCHEMBL8383792; BDBM50049015; 5-(4-Methanesulfonyl-phenyl)-6-(4-trifluoromethoxy-phenyl)-spiro[2.4]hept-5-ene; 6-(4-methylsulfonylphenyl)-5-[4-(trifluoromethoxy)phenyl]spiro[2.4]hept-5-ene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[97] | |||
| Compound Name |
4-(4-Fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-(pyridin-2-ylmethyl)pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL554903; BDBM50297705
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
1-Methyl-4-[2-(4-methylsulfonylphenyl)-1-cyclopentenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127674; SCHEMBL8652481; CTK0B0242; DTXSID30439389; ZINC3814638; BDBM50029625; 1-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]-4-methylbenzene; 1-methyl-4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzene; Benzene, 1-methyl-4-[2-[4-(methylsulfonyl)phenyl]-1-cyclopenten-1-yl]-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
1H-Pyrrole, 2-methyl-5-[4-(methylsulfonyl)phenyl]-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44068; 2-methyl-5-(4-methylsulfonylphenyl)-1H-pyrrole; BDBM50057878; 2-(4-Methanesulfonyl-phenyl)-5-methyl-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
(R)-6-Chloro-7,8-dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288696; SCHEMBL5643776; BDBM50331072; ZINC34019462; (2r)-6-chloro-7,8-dimethyl-2-(trifluoromethyl)-2h-chromene-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[68] | |||
| Compound Name |
3-(4-Iodo-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL126683; BDBM50150212
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
3-(4-Fluoro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL18040; SCHEMBL7829892; BDBM50125612; 3-(4-Fluorophenyl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one; 3-(4-fluorophenyl)-5-hydroxy-5-methyl-4-(4-methylsulfonylphenyl)furan-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
2-[6-Methoxy-2-(4-methylpyridine-2-carbonyl)-1H-indol-3-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1950010; SCHEMBL6169677; BDBM50365158
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[118] | |||
| Compound Name |
4-[3-(2-Fluorophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410358; BDBM50075036
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
6-Hydroxymethyletoricoxib
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL10042; UNII-8A0E1G55M9; 8A0E1G55M9; 6'-Desmethyl-6'-methylhydroxy Etoricoxib; 6'-Hydroxymethyl etoricoxib; 6'-Hydroxymethyl-etoricoxib; BDBM50099001; [5-[5-chloro-3-(4-methylsulfonylphenyl)pyridin-2-yl]pyridin-2-yl]methanol; 3-(4-Mesylphenyl)-5-chloro-2,3'-bipyridine-6'-methanol; (2,3'-Bipyridine)-6'-methanol, 5-chloro-3-(4-(methylsulfonyl)phenyl)-; (5-Chloro-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridin]-6'-yl)methanol; {5-[5-chloro-3-(4-methanesulfonylphenyl)pyridin-2-yl]pyridin-2-yl}methanol; 5-Chloro-3-(4-(methylsulfonyl)phenyl)(2,3'-bipyridine)-6'-methanol; (5-(5-Chloranyl-3-(4-methylsulfonylphenyl)pyridin-2-yl)pyridin-2-yl)methanol; [5-Chloro-3-(4-methanesulfonyl-phenyl)-[2,3'']bipyridinyl-6''-yl]-methanol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[110] | |||
| Compound Name |
2-Ethyl-1-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44194; SCHEMBL5698665; BDBM50057880; 2-Ethyl-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
2-(4-Methanesulfonyl-phenyl)-6-methyl-3-p-tolyl-pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL126578; SCHEMBL6975634; 6-methyl-3-(4-methylphenyl)-2-(4-methylsulfonylphenyl)pyran-4-one; BDBM50150217
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
1-(4-Fluorophenyl)-2-(4-methylsulfonylphenyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL291912; SCHEMBL215130; ZINC3814660; BDBM50049631; 1-(4-fluorophenyl)-2-[4-(methylsulfonyl)phenyl]benzene; 4''-Fluoro-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 4''''-Fluoro-4-methanesulfonyl-[1,1'';2'',1'''']terphenyl; 4-Fluoro-4''''-methanesulfonyl-[1,1'';2'',1'''']terphenyl; 4''''''''-Fluoro-4-methanesulfonyl-[1,1'''';2'''',1'''''''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
4-[3-Cyano-5-(4-fluorophenyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29136; SCHEMBL215235; BDBM50057579; 4-[3-Cyano-5-(4-fluoro-phenyl)-pyrazol-1-yl]-benzenesulfonamide; 4-[3-cyano-5-(4-fluorophenyl)-1h-pyrazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
1-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]-2,4-dichlorobenzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL108975; SCHEMBL213320; ZINC3814640; BDBM50037951; 2,4-dichloro-1-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzene; 2,4-Dichloro-1-[2-(4-methanesulfonyl-phenyl)-cyclopent-1-enyl]-benzene; 2,4-dichloro-1-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-yl}benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(3-methoxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3824003; BDBM50185923
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[48] | |||
| Compound Name |
2-(4-Tert-Butylphenyl)-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17111; BDBM50076862; 2-(4-tert-Butyl-phenyl)-4-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
1-(2-(4-(4-(Methylsulfonyl)-2-nitrophenoxy)phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775096; BDBM50343909
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
6-Bromo-5,7-dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3342568; BDBM50030824
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
6-Chloro-8-(4-methoxy-3-methylphenyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1669040; SCHEMBL5644710; BDBM50336019
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[75] | |||
| Compound Name |
1-Ethyl-4-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)-5-(trifluoromethyl)pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL68127; SCHEMBL216401; BDBM50289975; 1-Ethyl-4-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-5-trifluoromethyl-1H-pyrazole; 1-ethyl-4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[100] | |||
| Compound Name |
4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-5-trifluoromethyl-1H-pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306217; SCHEMBL6180483; BDBM50289974; 4-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)-5-(trifluoromethyl)-1H-pyrazole; 4-(4-fluorophenyl)-3-[4(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole; 4-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)-1H-pyrazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[100] | |||
| Compound Name |
5,5-Dimethyl-3-(1-methylethoxy)-4-(4-(methylsulfonyl)phenyl)-2(5H)-furanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
UNII-F2R32BF2CH; F2R32BF2CH; CHEMBL10345; SCHEMBL677786; BDBM50080081; 5,5-dimethyl-4-(4-methylsulfonylphenyl)-3-(2-propoxy)-5H-furanone; 3-Isopropoxy-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one; 3-Isopropoxy-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-2(5H)-furanone; 5,5-dimethyl-4-(4-methylsulfonylphenyl)-3-(2-propoxy)-5h-furan-2-one; 5,5-dimethyl-4-(4-methylsulfonylphenyl)-3-propan-2-yloxyfuran-2-one; 5.5-dimethyl-4-(4-methylsulfonylphenyl)-3-(2-propoxy)-5h-furan-2-one; 2(5H)-Furanone, 5,5-dimethyl-3-(1-methylethoxy)-4-(4-(methylsulfonyl)phenyl)-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[83] | |||
| Compound Name |
2-(4-Chloro-3-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42223; SCHEMBL5594262; BDBM50057977; 2-(4-chloro-3-methoxyphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-Phenyl-4-cyclohexyl-5-[4-(methylsulfonyl)phenyl]oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL350940; SCHEMBL7502304; BDBM50107520; 4-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-2-phenyl-oxazole; 4-cyclohexyl-5-(4-methylsulfonylphenyl)-2-phenyl-1,3-oxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[62] | |||
| Compound Name |
2-[2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazol-4-yl]acetonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43090; SCHEMBL5593896; BDBM50057944; [2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazol-4-yl]-acetonitrile; 2-(4-Chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-1H-imidazole-4-acetonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
3-Nitrooxypropyl 3-(5-chlorofuran-2-yl)-4-phenyl-1,2-oxazole-5-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380873; SCHEMBL2355270; BDBM50491530
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[89] | |||
| Compound Name |
(S)-3-[3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-pyridin-2-yloxy]-2-methyl-butan-2-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL47294; SCHEMBL6658046; BDBM50078595
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[81] | |||
| Compound Name |
4-[2-Oxo-4-(4-sulfamoyl-phenyl)-oxazol-3-yl]-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL307606; BDBM50084348
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[108] | |||
| Compound Name |
4-(5-Benzofuran-2-yl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29562; SCHEMBL6724514; BDBM50057558; 4-[5-(1-benzofuran-2-yl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
1-[2-(4-Phenoxyphenoxy)ethyl]pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL162424; SCHEMBL7141714; BDBM50085245; ZINC13805349; 1-[2-(4-Phenoxy-phenoxy)-ethyl]-pyrrolidine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
4-[5-(4-Chlorophenyl)-3-(cyanomethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL286756; SCHEMBL6315704; BDBM50057519; 4-[5-(4-Chloro-phenyl)-3-cyanomethyl-pyrazol-1-yl]-benzenesulfonamide; 4-[5-(4-chlorophenyl)-3-(cyanomethyl)-1H-pyrazol-1-yl]benzenesulfonamide; 4-[5-(4-chlorophenyl)-3-cyanomethyl-1-H-pyrazol-1-yl]benzenesulfonamide; 4-[5-(4-chlorophenyl)-3-cyanomethyl-1H-pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
2-(2-Chlorophenyl)-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL277115; SCHEMBL214091; BDBM50076873; 2-(2-chlorophenyl)-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-1,3-thiazole; 2-(2-Chloro-phenyl)-4-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazole; 2-(2-Chlorophenyl)-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
5-[4,5-Difluoro-2-(4-methylsulfonylphenyl)phenyl]-2-methylpyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL299251; SCHEMBL6721511; BDBM50049628; 5-(4,5-Difluoro-4''-methanesulfonyl-biphenyl-2-yl)-2-methyl-pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
4-[3-(3-Fluorophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410345; BDBM50074902
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
4-[3-(4-Chlorophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410360; BDBM50075038
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-N,N-dimethyl-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL282391; SCHEMBL5698718; BDBM50057577; 4-[5-(4-fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]-N,N-dimethylbenzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
4-[3-[4-(Trifluoromethyl)phenyl]-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410352; BDBM50074910
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
2-(4-Chlorophenyl)-4-(fluoromethyl)-1-(4-methylsulfonylphenyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43265; SCHEMBL5594332; BDBM50057979; 2-(4-Chloro-phenyl)-4-fluoromethyl-1-(4-methanesulfonyl-phenyl)-1H-imidazole; 2-(4-Chlorophenyl)-4-fluoromethyl-1-[4-(methylsulfonyl)phenyl]-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
1-(2-(4-(2,4-Dinitrophenoxy)phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775090; BDBM50343903
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
4-[2-(3,4-Difluorophenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL111657; SCHEMBL8653672; ZINC3814646; BDBM50029604; 1,2-difluoro-4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzene; 1,2-Difluoro-4-[2-(4-methanesulfonyl-phenyl)-cyclopent-1-enyl]-benzene; 1,2-difluoro-4-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-yl}benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[73] | |||
| Compound Name |
3-Cyclopentyloxy-4-(4-methanesulfonyl-phenyl)-5,5-dimethyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL307602; SCHEMBL5210738; BDBM50080085; 3-cyclopentyloxy-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one; 3-(Cyclopentyloxy)-4-[4-(methylsulfonyl)phenyl]-5,5-dimethyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[22] | |||
| Compound Name |
4-(4-(Methylsulfonyl)phenyl)-N-phenyl-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561950; BDBM50297680
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
4-[5-Tert-butyl-3-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3963184; SCHEMBL12495202; BDBM236657; US9388139, 26
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
4-[2-(3,4-Dimethoxyphenyl)-4,5-difluorophenyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL52888; SCHEMBL6721656; BDBM50049616; 4',5'-Difluoro-4'',5''-dimethoxy-1,1':2',1''-terbenzene-4-sulfonamide; 4'',5''-Difluoro-3,4-dimethoxy-[1,1'';2'',1'''']terphenyl-4''''-sulfonic acid amide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
N-[6-(5-Methyl-pyridin-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL37371; BDBM50073859; N-[6-(5-methylpyridin-2-yl)sulfanyl-1-oxo-2,3-dihydroinden-5-yl]methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
7-Methoxy-3-(3'',5''-dimethoxyphenyl)coumarin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL199527; BDBM50176522
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[67] | |||
| Compound Name |
2-(4-Chlorobenzyloxy)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL46171; BDBM50078586; 2-(4-Chloro-benzyloxy)-3-(4-methanesulfonyl-phenyl)-5-trifluoromethyl-pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[81] | |||
| Compound Name |
4-[3-Difluoromethyl-5-(2,5-dimethyl-phenyl)-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL280772; BDBM50057603
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
6,8-Dibromo-5,7-dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3342569; BDBM50030825
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
4-(4-(Methylsulfonyl)phenyl)-N-(piperidin-4-yl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL549519; BDBM50297662
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
3-[5-Chloro-3-(4-methanesulfonyl-phenyl)-3H-imidazol-4-yl]-4-methyl-pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL116253; BDBM50131589
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[76] | |||
| Compound Name |
4-[3-(2-Fluorophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410344; BDBM50074900
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
3-(4-Fluorophenyl)-2-(4-(methylsulfonyl)phenyl)thiazolidin-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL249995; SCHEMBL5670285; 3-(4-fluorophenyl)-2-(4-methylsulfonylphenyl)-1,3-thiazolidin-4-one; BDBM50221108
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[51] | |||
| Compound Name |
2-(4-Chlorophenyl)-4-(difluoromethyl)-1-(4-methylsulfonylphenyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL46636; SCHEMBL5594179; BDBM50057930; 2-(4-Chloro-phenyl)-4-difluoromethyl-1-(4-methanesulfonyl-phenyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-(4-Fluoro-phenyl)-6-isopropoxy-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL365473; BDBM50153983
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
2,4,6-Trimethyl-3-(5-methyl-4-phenyl-isoxazol-3-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL185638; CTK5E4609; DTXSID70461780; BDBM50153043; 2,4,6-Trimethyl-3-(5-methyl-4-phenylisoxazol-3-yl)benzenesulfonamide; Benzenesulfonamide,2,4,6-trimethyl-3-(5-methyl-4-phenyl-3-isoxazolyl)-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[94] | |||
| Compound Name |
N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-indan-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL289262; SCHEMBL6247997; BDBM50048190; N-[1-oxo-6-(1,3-thiazol-2-ylsulfanyl)-2,3-dihydroinden-5-yl]methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
3-[4-(Difluoromethyl)-1-(4-methylsulfonylphenyl)imidazol-2-yl]pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL322720; SCHEMBL5594043; BDBM50091179; 3-[4-Difluoromethyl-1-(4-methanesulfonyl-phenyl)-1H-imidazol-2-yl]-pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
3-[1-(3-Chloro-phenoxy)-2,2,2-trifluoro-ethyl]-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43647; BDBM50057889
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL170591; SCHEMBL9248065; BDBM50286942
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
3-(4-Chlorophenyl)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL126629; SCHEMBL5708993; BDBM50150189; 3-(4-Chloro-phenyl)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
Benzenesulfonamide, 4-[(4-hydroxy-3-methoxyphenyl)azo]-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL214710; NSC720348; ACMC-20m88k; CTK0D7508; DTXSID30761758; BDBM50190332; NSC-720348; 4-(3-Methoxy-4-hydroxyphenylazo)benzenesulfonamide; 4-(4-Hydroxy-3-methoxy-phenylazo)-benzenesulfonamide; 4-((4-hydroxy-3-methoxyphenyl)diazenyl)benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
4-[2-(3,5-Dichloro-4-methoxyphenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL321160; BDBM50029599; 1,3-dichloro-2-methoxy-5-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-yl}benzene; 1,3-Dichloro-5-[2-(4-methanesulfonyl-phenyl)-cyclopent-1-enyl]-2-methoxy-benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[73] | |||
| Compound Name |
(S)-6-Chloro-7-(isobutyl(methyl)amino)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630256; SCHEMBL5642924; BDBM50332776; (2S)-6-chloro-7-[methyl(2-methylpropyl)amino]-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[70] | |||
| Compound Name |
3-(4-Fluorophenoxy)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127084; SCHEMBL1375790; BDBM50150218; 3-(4-Fluoro-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
4-[2-(3,4,5-Trifluorophenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL358140; BDBM50029621; ZINC13744290; 1,2,3-Trifluoro-5-[2-(4-methanesulfonyl-phenyl)-cyclopent-1-enyl]-benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[73] | |||
| Compound Name |
(3S,4S)-4-(4-Methanesulfonyl-phenyl)-3-phenyl-dihydro-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL313584; trans-Dhr; trans-Dihydrorofecoxib; trans-3',4'-Dihydrorofecoxib; BDBM50094983; UNII-IU92DC6Q4C component PHCFUFKRCHEUTJ-HZPDHXFCSA-N; Rel-(3R,4R)-dihydro-4-(4-(methylsulfonyl)phenyl)-3-phenyl-2(3H)-furanone; 2(3H)-Furanone, dihydro-4-(4-(methylsulfonyl)phenyl)-3-phenyl-, (3R,4R)-rel-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[104] | |||
| Compound Name |
2-Methyl-5-(4-methylsulfonylphenyl)-1-[4-(trifluoromethyl)phenyl]pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42085; SCHEMBL7210378; BDBM50057899; 2-(4-Methanesulfonyl-phenyl)-5-methyl-1-(4-trifluoromethyl-phenyl)-1H-pyrrole; 2-methyl-5-[4-(methylsulfonyl)phenyl]-1-[4-(trifluoromethyl)phenyl]-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
2-(2-Chloro-6-methyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43654; SCHEMBL8885021; BDBM50057986; 2-(2-chloro-6-methylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
3-[1-(4-Methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]aniline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44924; SCHEMBL5594259; BDBM50057952; 3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-phenylamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
1-Phenyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL297008; SCHEMBL3831175; BDBM50057906; 2-methyl-5-(4-methylsulfonylphenyl)-1-phenylpyrrole; 2-(4-Methanesulfonyl-phenyl)-5-methyl-1-phenyl-1H-pyrrole; 2-methyl-5-[4-(methylsulfonyl)phenyl]-1-phenyl-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
6-Chloro-7-((2,5-dimethylpyrrolidin-1-yl)methyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630245; 6-chloro-7-[(2,5-dimethylpyrrolidin-1-yl)methyl]-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid; SCHEMBL5807380; BDBM50332756
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[70] | |||
| Compound Name |
4-[5-(Difluoromethyl)-2-(4-sulfamoylphenyl)pyrazol-3-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29333; SCHEMBL5425139; BDBM50057598; 4-[5-Difluoromethyl-2-(4-sulfamoyl-phenyl)-2H-pyrazol-3-yl]-benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
1-(2-(4-(4-(Trifluoromethyl)phenoxy)phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775101; BDBM50343914
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
6-Chloro-7-(diisopropylamino)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630246; BDBM50332757
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[70] | |||
| Compound Name |
2-(3-Fluoro-5-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL295752; SCHEMBL5594059; BDBM50057956; 2-(3-fluoro-5-methoxyphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-(Cyclohexylamino)-6-(4-(methylsulfonyl)phenyl)pyrimidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL570773; BDBM50297655
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
3-Benzo[b]thiophen-2-yl-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL277519; BDBM50125623; 3-(Benzo[b]thiophene-2-yl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
3-(2-Methoxyoxolan-2-yl)-1-(4-methylphenyl)-5-(4-methylsulfonylphenyl)pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL190011; SCHEMBL5323128; BDBM50156456; 5-(4-Methanesulfonyl-phenyl)-3-(2-methoxy-tetrahydro-furan-2-yl)-1-p-tolyl-1H-pyrazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[119] | |||
| Compound Name |
5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-isothiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL366807; SCHEMBL7626404; BDBM50286940; AKOS000279448; 5-(4-fluorophenyl)-4-(4-methylsulfonylphenyl)-1,2-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazole-4-carbaldehyde
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL414162; SCHEMBL5594132; BDBM50057924; 2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole-4-carbaldehyde; 2-(4-Chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-1H-imidazole-4-carboxaldehyde
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
(2R)-2-[4-[[(1R,2S)-2-Hydroxycyclopentyl]methyl]phenyl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL417452; BDBM50140317; ZINC28220807; (R)-2-[4-((1R,2S)-2-Hydroxy-cyclopentylmethyl)-phenyl]-propionic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[42] | |||
| Compound Name |
3-(4-Methylsulfonylphenyl)-2-pyridin-3-ylpyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329419; BDBM50072062; 3-(4-Methanesulfonyl-phenyl)-[2,3'']bipyridinyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[59] | |||
| Compound Name |
4-[3-(2-Bromophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410348; BDBM50074906
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
4-[5-(4-Fluorophenyl)-4-propyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29941; SCHEMBL5698589; BDBM50057545; 4-[5-(4-Fluoro-phenyl)-4-propyl-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
3-[(3-Ethoxy)phenoxymethyl]-1-(4-methanesulfonylphenyl)-5-phenyl-1H-pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL436494; BDBM50156593
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-Methyl-3-[1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]aniline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL46667; SCHEMBL5594526; BDBM50057993; {3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-phenyl}-methyl-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-{4-[4-Chloro-1-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl]-2-fluorophenoxy}ethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219893; BDBM50206925
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[96] | |||
| Compound Name |
[1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrol-3-ylmethyl]-dimethyl-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42801; BDBM50057876
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
1,4-Benzodioxan-6-ylacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetic acid; (2,3-Dihydro-benzo[1,4]dioxin-6-yl)-acetic acid; 2-(2,3-dihydro-1,4-benzodioxin-6-yl)acetic acid; 2,3-dihydro-1,4-benzodioxin-6-ylacetic acid; 1,4-benzodioxan-6-ylaceticacid; CHEMBL235786; 2-(2H,3H-benzo[3,4-e]1,4-dioxin-6-yl)acetic acid; EINECS 241-286-9; PubChem17716; Enamine_005765; Oprea1_471639; SCHEMBL286952; 1,4-benzodioxane-6-acetic acid; CTK0H7192; DTXSID00169343; HMS1410G01; ZINC3750721; 8884AA; ANW-66336; BDBM50213566; MFCD00066923; SBB010906; STK279214; AKOS000117663; CCG-120458; MCULE-3823468718; 1,4-Benzodioxane-6-acetic acid, 97%; IDI1_008000; BS-13882; DB-011454; ST4143452; 2,3-Dihydro-1,4-benzodioxin-6-acetic acid; BB 0248975; CS-0102793; FT-0677801; 1,4-Benzodioxin-6-aceticacid, 2,3-dihydro-; EN300-05691; Z-0289; 2-(2,3-dihydro-1,4-benzodioxin-6-yl) acetic acid; Z56921840
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[120] | |||
| Compound Name |
1-(4-Methylsulfonylphenyl)-2-(3-nitrophenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42549; SCHEMBL5594873; BDBM50057934; 1-(4-Methanesulfonyl-phenyl)-2-(3-nitro-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
4-[5-(2-Dimethylamino-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL27733; BDBM50057517; 4-[3-(Trifluoromethyl)-5-[2-(dimethylamino)phenyl]-1H-pyrazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
4-[5-(Difluoromethyl)-2-(4-sulfamoylphenyl)pyrazol-3-yl]benzoic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL440798; SCHEMBL6352074; BDBM50057586; 4-[5-Difluoromethyl-2-(4-sulfamoyl-phenyl)-2H-pyrazol-3-yl]-benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
2-[1-(Trifluoromethyl)-2,2,2-trifluoroethoxy]-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL49918; BDBM50078591; 3-(4-Methanesulfonyl-phenyl)-5-trifluoromethyl-2-(2,2,2-trifluoro-1-trifluoromethyl-ethoxy)-pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[81] | |||
| Compound Name |
2-(3-Chloro-4-methylsulfanyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42277; SCHEMBL5594495; BDBM50057908; 2-(3-chloro-4-methylsulfanylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
Methyl 3-[(4-nitronaphthalen-1-yl)amino]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3950016; SCHEMBL13465104; BDBM220115; US9271961, 13
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[105] | |||
| Compound Name |
1-(2-(4-(2-(Trifluoromethyl)phenoxy)phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775099; BDBM50343912
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
1-(4-Fluorophenyl)-4-hydroxymethyl-5-methyl-2-(4-methylsulfonylphenyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44101; SCHEMBL5313386; BDBM50057891; [1-(4-fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrol-3-yl]methanol; [1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrol-3-yl]-methanol; 1-(4-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole-3-methanol; 1-(4-Fluorophenyl)-3-(1-hydroxyl)methyl-2-methyl-5-(4-methylsulfonylphenyl)pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
N-(4-Fluorobenzyl)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551148; N-(4-fluorobenzyl)-4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)pyrimidin-2-amine; SCHEMBL5787610; BDBM50297675; N-[(4-fluorophenyl)methyl]-4-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-2-amine; N-(4-fluorobenzyl)-4-[4-(methylsulfonyl)-phenyl]-6-(trifluoro-methyl)pyrimidin-2-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2-Chloro-4-(4-cyclohexyl-2-methyl-oxazol-5-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL36722; 2-chloro-4-(4-cyclohexyl-2-methyl-1,3-oxazol-5-yl)benzenesulfonamide; BDBM50110993
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
4-[2-(3-Chloro-4-methoxyphenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL324863; SCHEMBL213834; BDBM50029620; ZINC13744278; 2-chloro-1-methoxy-4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzene; 2-chloro-1-methoxy-4-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-yl}benzene; 2-Chloro-4-[2-(4-methanesulfonyl-phenyl)-cyclopent-1-enyl]-1-methoxy-benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[73] | |||
| Compound Name |
3-(3-Chloro-4-methoxy-phenyl)-2-(4-methanesulfonyl-phenyl)-benzofuran
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77350; BDBM50285519
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[101] | |||
| Compound Name |
4-(3-Difluoromethyl-8-fluoro-7-methoxy-5H-isothiochromeno[4,3-c]pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL318464; BDBM50288321
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[93] | |||
| Compound Name |
1-Cyclohexyl-2-methyl-5-(4-methylsulfonylphenyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43864; SCHEMBL7209869; BDBM50057890; 1-Cyclohexyl-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole; 1-cyclohexyl-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
4-[5-Tert-butyl-3-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3965079; SCHEMBL12493310; BDBM236654; US9388139, 23
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-Amino-N-[2-(trifluoromethyl)phenyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL264163; CTK7D9442; ZINC5899404; BDBM50376397; STK253946; AKOS000148507; MCULE-1861890926; ST51030148; N-[2-(Trifluoromethyl)phenyl]-2-aminobenzamide; (2-aminophenyl)-N-[2-(trifluoromethyl)phenyl]carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
4-[3-(Difluoromethyl)-5-(4-methylsulfonylphenyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL28084; SCHEMBL3243184; BDBM50057526; 4-[3-Difluoromethyl-5-(4-methanesulfonyl-phenyl)-pyrazol-1-yl]-benzenesulfonamide; 4-[5-(4-[methylsulfonyl] phenyl)-3-(difluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide; 4-[5-(4-[methylsulfonyl]phenyl)-3-(difluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
4-[5-Tert-butyl-3-(4-ethoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3976289; SCHEMBL12524150; BDBM236646; US9388139, 15
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-(3-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL405319; BDBM50376401
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
N-[1-Oxo-6-(thiazol-2-ylsulfanyl)-1,3-dihydro-isobenzofuran-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL287909; SCHEMBL8592711; BDBM50073867
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
2-Fluoro-1-methoxy-4-[2-(4-methylsulfonylphenyl)phenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL54605; SCHEMBL6721564; BDBM50049664; ZINC29545390; 2-fluoro-1-methoxy-4-[2-[4-(methylsulfonyl)phenyl]phenyl]benzene; 3''-Fluoro-4''-methoxy-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 3-Fluoro-4''''-methanesulfonyl-4-methoxy-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
2,4,6-Trimethyl-3-[5-methyl-4-(4-sulfamoyl-phenyl)-isoxazol-3-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL189701; BDBM50153045
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[94] | |||
| Compound Name |
6-Chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288771; SCHEMBL5171883; BDBM50331066; (2S)-6-Chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-1-benzopyran-3-carboxylic acid; 6-Chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid, AldrichCPR
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
3-(4-Fluorophenyl)-4-(4-methylsulfonylphenyl)thiophene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL319306; SCHEMBL6050724; BDBM50286046; 3-(4-methylsulfonylphenyl)-4-(4-fluorophenyl)thiophene; 4-(4 methylsulfonylphenyl)-3-(4-fluorophenyl)thiophene; 3-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
3-Methyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]isoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329716; BDBM50103315; 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-3-methyl-isoxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[116] | |||
| Compound Name |
(S)-3-Ethyl-2-[3-(4-methanesulfonyl-phenyl)-5-trifluoromethyl-pyridin-2-yloxy]-pentan-3-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL48073; SCHEMBL6657357; BDBM50078594
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[81] | |||
| Compound Name |
4-[5-Tert-butyl-3-(3-fluorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3963234; SCHEMBL12524143; BDBM236650; US9388139, 19
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
N-(4-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)phenyl)methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775110; BDBM50343923
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
8-Ethyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1290565; SCHEMBL5171215; BDBM50030826; (2S)-8-Ethyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-1-benzopyran-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
2-(4-Methanesulfonyl-phenyl)-6-methyl-3-phenyl-pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127268; SCHEMBL6977125; BDBM50150195; 6-methyl-2-(4-methylsulfonylphenyl)-3-phenylpyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
3-(4-Methanesulfonyl-phenyl)-6-methoxy-2-p-tolyl-pyrazolo[1,5-b]pyridazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL184187; BDBM50153999
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
5-Methyl-3-(oxolan-2-yl)-4-phenyl-1,2-oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380875; SCHEMBL2280511; BDBM50491538
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[89] | |||
| Compound Name |
2-(4-Fluorophenyl)-3-(4-methylsulfonylphenyl)thiophene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL305060; SCHEMBL8985356; CTK3B6962; DTXSID50438374; BDBM50285227; 2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]thiophene; 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-thiophene; Thiophene, 2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[36] | |||
| Compound Name |
1-Fluoro-4-[2-(4-methylsulfonylphenyl)-4,4-di(trifluoromethyl)-1-cyclopentenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL111045; SCHEMBL8652917; BDBM50037950; 1-fluoro-4-[2-(4-methylsulfonylphenyl)-4,4-bis(trifluoromethyl)cyclopenten-1-yl]benzene; 1-Fluoro-4-[2-[4-(methylsulfonyl)phenyl]-4,4-bis(trifluoromethyl)-1-cyclopentenyl]benzene; 1-fluoro-4-[2-[4-(methylsulfonyl)phenyl]-4,4-bis(trifluoromethyl)cyclopent-1-en-1-yl]benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
2-(5-Fluoro-2-methyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL274798; SCHEMBL8885240; BDBM50057991; 2-(5-fluoro-2-methylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-(3,5-Dichloro-phenyl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL282924; SCHEMBL3821955; BDBM50075656; 2-(3,5-dichlorophenyl)-3-(4-methylsulfonylphenyl)cyclopent-2-en-1-one; 2-(3,5-Dichlorophenyl)-3-[4-(methylsulfonyl)phenyl]-2-cyclopentene-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[65] | |||
| Compound Name |
4-[4-Chloro-5-[3-fluoro-4-(3-hydroxypropoxy)phenyl]imidazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL386006; BDBM50206926; 4-{4-chloro-5-[3-fluoro-4-(2-hydroxypropoxy)phenyl]-1Himidazol-1-yl}benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[96] | |||
| Compound Name |
1-[(4-Chlorophenyl)carbonyl]-2-methyl-3-({N-[3-(nitrooxy)-propyl]carbamoyl}methyl)indol-5-yl aminosulfonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL237205; BDBM50226645
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[111] | |||
| Compound Name |
N-[6-(4-Ethyl-thiazol-2-ylsulfanyl)-1-oxo-1,3-dihydro-isobenzofuran-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43461; SCHEMBL4576299; BDBM50073858; N-[6-[(4-ethyl-1,3-thiazol-2-yl)sulfanyl]-1-oxo-3H-2-benzofuran-5-yl]methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
4-[2-(5-Methoxypyridin-3-yl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL322305; SCHEMBL5594237; BDBM50091206; 4-[2-(5-Methoxy-pyridin-3-yl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
2,2,2-Trifluoro-1-[4-[5-(4-fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]phenyl]ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL285567; BDBM50057594; 2,2,2-Trifluoro-1-{4-[5-(4-fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-phenyl}-ethanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
3-[4-(Pentafluoro-lambda6-sulfanyl)anilino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623737; BDBM50124574
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[117] | |||
| Compound Name |
3-[(4-Chlorophenyl)Amino]Benzoic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1682203; SCHEMBL13280280; 3-(4-chloroanilino)benzoic acid; BDBM50337284; ZINC66078766; 3-[N-(4-chlorophenyl)amino]benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[105] | |||
| Compound Name |
1-(4-Fluorophenyl)-2-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL417894; SCHEMBL3240027; BDBM50057958; 1-(4-Fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole; 1-(4-fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-Chloro-4-[4,5-difluoro-2-(4-methylsulfonylphenyl)phenyl]-N,N-dimethylaniline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL299806; SCHEMBL6721692; BDBM50049649; 2-chloro-4-[4,5-difluoro-2-[4-(methylsulfonyl)phenyl]phenyl]-N,N-dimethylbenzenamine; 4-(Methylsulfonyl)-4''-(dimethylamino)-4',5'-difluoro-5''-chloro-1,1':2',1''-terbenzene; (3-Chloro-4'',5''-difluoro-4''''-methanesulfonyl-[1,1'';2'',1'''']terphenyl-4-yl)-dimethyl-amine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
4-[3-(4-Bromophenyl)-3a,4-dihydro-3H-chromeno[4,3-c]pyrazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410362; BDBM50075040
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
1-(3-Chloro-4-fluorophenyl)-4,5-difluoro-2-(4-methylsulfonylphenyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL52760; SCHEMBL6724457; ZINC3814762; BDBM50049642; 3''-Chloro-4',4'',5'-trifluoro-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 3-Chloro-4,4'',5''-trifluoro-4''''-methanesulfonyl-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
4-[2-(3-Chloro-5-methyl-phenyl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42709; SCHEMBL5069832; BDBM50057907; 4-[2-(3-chloro-5-methylphenyl)-4-(trifluoromethyl)-1H-imidazol-1-yl]benzenesulfonamide; 4-[2-(3-chloro-5-methylphenyl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
4-[5-(4-Chlorophenyl)-3-(hydroxymethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL282838; 4-(5-(4-chlorophenyl)-3-hydroxymethyl-1H-pyrazol-1-yl]benzenesulfonamide; 4-[5-(4-chlorophenyl)-3-hydroxymethyl-1H-pyrazol-1-yl]benzenesulfonamide; SCHEMBL213633; BDBM50057524; 4-[5-(4-Chloro-phenyl)-3-hydroxymethyl-pyrazol-1-yl]-benzenesulfonamide; 4-[5-(4-chlorophenyl) -3-hydroxymethyl-1H-pyrazol-1-yl]benzenesulfonamide; 4-[5-(4-chlorophenyl)-3-hydroxymethyl-1h pyrazol-1-yl]benzenesulfonamide; 4-[5-(4-chlorophenyl)-3-hydroxymethyl-1H-pyrazol-1yl]benzenesulfonamide; 4-[3-(Hydroxymethyl)-5-(4-chlorophenyl)-1H-pyrazole-1-yl]benzenesulfonamide; 4-[5-(4-Chlorophenyl)-3-(hydroxymethyl)-1H-pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
4-(4-Methyl-5-phenyl-pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL280573; SCHEMBL6344616; BDBM50057595; ZINC13761857; 4-(4-methyl-5-phenylpyrazol-1-yl)benzenesulfonamide; 4-(4-Methyl-5-phenyl-1H-pyrazole-1-yl)benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
4-[5-(4-Cyanophenyl)-3-(difluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL281504; SCHEMBL6341878; BDBM50057617; 4-[5-(4-Cyano-phenyl)-3-difluoromethyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
3-(2-Acetoxyphenyl)-4-[4-(methylsulfonyl)phenyl]-2,5-dihydrofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328616; BDBM50118681; Acetic acid 2-[4-(4-methanesulfonyl-phenyl)-2-oxo-2,5-dihydro-furan-3-yl]-phenyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[114] | |||
| Compound Name |
4-[5-(4-Fluorophenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3954425; SCHEMBL12492697; BDBM236658; US9388139, 27
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
(2RS,4R)-2-(1,3-diphenyl-1H-pyrazol-4-yl)thiazolidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1631309; BDBM50332955
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[87] | |||
| Compound Name |
N-(3-Phenylsulfonyl-4-pyridinyl)methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL224256; CTK3D2865; DTXSID30465229; BDBM50158434; Methanesulfonamide, N-[3-(phenylsulfonyl)-4-pyridinyl]-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[112] | |||
| Compound Name |
2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-6-methyl-pyrazolo[1,5-b]pyridazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL185621; BDBM50153991
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
[2'-[(Cyclopropanecarbonyl-ethyl-amino)-methyl]-4'-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetic acid sodium salt
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1668898
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[121] | |||
| Compound Name |
2-(3,4-Difluorophenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42595; SCHEMBL215436; BDBM50057959; 1-[4-(Methylsulfonyl)phenyl]-2-(3,4-difluorophenyl)-4-(trifluoromethyl)-1H-imidazole; 2-(3,4-Difluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
4-(4-(Methylsulfonyl)phenyl)-N-propyl-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL558728; BDBM50297673
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
Phenylmethyl 2-{6-chloro-1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methylindol-3-yl}acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400428; BDBM50226640; benzyl 2-[6-chloro-1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[111] | |||
| Compound Name |
2-(4-Methanesulfonyl-phenyl)-6-methyl-3-(4-nitro-phenoxy)-pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL129473; BDBM50150191
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
1,2-Difluoro-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL442164; SCHEMBL6724238; CTK0A7283; DTXSID40441599; BDBM50049632; ZINC13755787; 4',4'',5'-Trifluoro-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 1,1':2',1''-Terphenyl, 4,4',5'-trifluoro-4''-(methylsulfonyl)-; 4'',5'',4''''-Trifluoro-4-methanesulfonyl-[1,1'';2'',1'''']terphenyl; 4,4'',5''-Trifluoro-4''''-methanesulfonyl-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-(2-hydroxyphenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3823420; BDBM50185927
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[48] | |||
| Compound Name |
6-[4-(Methylsulfonyl)phenyl]-5-[3-chloro-4-methoxyphenyl]spiro[2.4]hept-5-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL88899; SCHEMBL215587; BDBM50049019; 5-(3-Chloro-4-methoxy-phenyl)-6-(4-methanesulfonyl-phenyl)-spiro[2.4]hept-5-ene; 6-(3-chloro-4-methoxyphenyl)-5-(4-methylsulfonylphenyl)spiro[2.4]hept-5-ene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[97] | |||
| Compound Name |
1-(4-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)-3-(trifluoromethylsulfonyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44244; SCHEMBL7210593; BDBM50057903; 1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-3-trifluoromethanesulfonyl-1H-pyrrole; 1-(4-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-3-[(trifluoromethyl)sulfonyl]-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
4-(4-Fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole-2-carboxylic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL279133; BDBM50076869; 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazole-2-carboxylic acid ethyl ester; ethyl 4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-1,3-thiazole-2-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
4-[3-(4-Methoxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
KUC103375N; UNM-0000306085; CHEMBL3979746; SCHEMBL12493661; BDBM54632; cid_5181298; AKOS005154041; MCULE-6749189500; US9388139, 7; 4-[5-(4-methoxyphenyl)-3-phenyl-2-pyrazolin-1-yl]benzoic acid; 4-(5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid; 4-(5-(4-METHOXY-PHENYL)-3-PHENYL-4,5-DIHYDRO-PYRAZOL-1-YL)-BENZOIC ACID
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
1-(4-Methanesulfonyl-phenyl)-2-pyridin-3-yl-1H-imidazole-4-carboxylic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL110396; BDBM50091185
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
1-Isopropyl-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43863; BDBM50057866
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
2-(4-Chloro-phenyl)-4-(4-chloro-phenylsulfanylmethyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL298084; BDBM50057938
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazole-4-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL295654; SCHEMBL5594360; BDBM50057928; 1-[4-(Methylsulfonyl)phenyl]-2-(4-chlorophenyl)-1H-imidazole-4-carboxylic acid; 2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole-4-carboxylic acid; 2-(4-chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-1H-imidazole-4-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
N-(2-Aminophenyl)-2-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL406881; CTK7D9610; BDBM50376393; AKOS000130605
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
[2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazol-4-yl]methanamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL294969; SCHEMBL8884605; BDBM50057996; C-[2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazol-4-yl]-methylamine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
3-Nitro-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenoxy)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775098; BDBM50343911
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
1-(4-Methanesulfonyl-phenyl)-2-(4-methoxy-2,5-dimethyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42074; BDBM50057942
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
3-[1-(4-Chlorobenzoyl)-5-methoxy-3-methylindol-2-yl]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2323507; SCHEMBL4548569; BDBM50427620; 3-(1-(4-chlorobenzoyl)-5-methoxy-3-methyl-1H-indol-2-yl)propanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[10] | |||
| Compound Name |
1h-Indole,1-methyl-3-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1h-imidazol-2-yl]-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL323954; SCHEMBL5594100; BDBM50091201; ZINC13812862; 1-methyl-3-[1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]indole; 1-[4-(Methylsulfonyl)phenyl]-2-(1-methyl-1H-indole-3-yl)-4-(trifluoromethyl)-1H-imidazole; 3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-1-methyl-1H-indole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
Glucuronide conjugate OF 5-hydroxy rofecoxib
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303696; BDBM50451153
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[104] | |||
| Compound Name |
4-[5-(4-Fluoro-phenyl)-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29662; BDBM50057549
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
2-(2-Chlorophenyl)-4-(3-thienyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17179; SCHEMBL7832505; BDBM50076861; 2-(2-Chloro-phenyl)-5-(4-methanesulfonyl-phenyl)-4-thiophen-3-yl-thiazole; 2-(2-chlorophenyl)-5-(4-methylsulfonylphenyl)-4-thiophen-3-yl-1,3-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
5-Hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-3-thiophen-2-yl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL275650; BDBM50125614; 3-(2-Thienyl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-[1,2,3]thiadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL368409; SCHEMBL8918341; BDBM50286952
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
3-(4-Methanesulfonyl-phenyl)-2-phenyl-pyrazolo[1,5-b]pyridazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL365865; BDBM50153994; 3-(4-methylsulfonylphenyl)-2-phenylpyrazolo[1,5-b]pyridazine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
3-(3-Chloro-2,4,6-trimethoxy-phenyl)-5-methyl-4-phenyl-isoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL188739; BDBM50153037
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[94] | |||
| Compound Name |
5-Chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridine] 1'-oxide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
UNII-FP09886CY9; CHEMBL274841; FP09886CY9; Etoricoxib N-Oxide; Etoricoxib N1'-Oxide; Etoricoxib 1'-N'-oxide; Etoricoxib-N1'-oxide; Etoricoxib-1'-N-oxide; Etoricoxib N 1'-Oxide; 5-Chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide; DTXSID50658090; KS-00000U0Z; BDBM50099002; MFCD30609556; ZINC26007998; ACN-027566; AK601636; BS-16869; FT-0668438; Etoricoxib N1 inverted exclamation mark -Oxide; A1-04617; 3-(4-Mesylphenyl)-5-chloro-6'-methyl-2,3'-bipyridine 1'-oxide; 2,3'-Bipyridine, 5-chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-, 1'-oxide; 5-(5-chloro-3-(4-(methylsulfonyl)phenyl)pyridin-2-yl)-2-methylpyridine 1-oxide; 5-Chloro-3-(4-methanesulfonyl-phenyl)-6''-methyl-[2,3'']bipyridinyl 1''-oxide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[110] | |||
| Compound Name |
6-Ethoxy-2-(4-fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL183891; BDBM50153984
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
1-(3,4-Dimethylphenyl)-4,5-difluoro-2-(4-methylsulfonylphenyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL300601; SCHEMBL6724462; BDBM50049640; 1,2-difluoro-4-(3,4-dimethylphenyl)-5-[4-(methylsulfonyl)phenyl]benzene; 4'',5''-Difluoro-4''''-methanesulfonyl-3,4-dimethyl-[1,1'';2'',1'''']terphenyl; 4-(Methylsulfonyl)-4',5'-difluoro-4'',5''-dimethyl-1,1':2',1''-terbenzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
1-(3-Chloro-4-methylphenyl)-4,5-difluoro-2-[4-(methylsulfonyl)phenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL417748; SCHEMBL6725556; BDBM50049637; 1-(3-chloro-4-methylphenyl)-4,5-difluoro-2-(4-methylsulfonylphenyl)benzene; 3-Chloro-4'',5''-difluoro-4''''-methanesulfonyl-4-methyl-[1,1'';2'',1'''']terphenyl; 4-(Methylsulfonyl)-4''-methyl-4',5'-difluoro-5''-chloro-1,1':2',1''-terbenzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
2-(2-Chlorophenyl)-4-(3-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL279752; SCHEMBL7840959; BDBM50076853; 2-(2-Chloro-phenyl)-4-(3-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazole; 2-(2-chlorophenyl)-4-(3-fluorophenyl)-5-(4-methylsulfonylphenyl)-1,3-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
Benzenesulfonamide,4-(3-methyl-5-phenyl-1h-pyrazol-1-yl)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29492; SCHEMBL5226958; BDBM50057599; ZINC13761841; V2-05; 4-(3-Methyl-5-phenyl-pyrazol-1-yl)-benzenesulfonamide; 4-(3-Methyl-5-phenyl-1H-pyrazol-1-yl)benzenesulfonamide; 4-(3-METHYL-5-PHENYLPYRAZOL-1-YL)BENZENESULFONAMIDE
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
5-Hydroxyrofecoxib
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-Hydroxy Vioxx; 5-HYDROXY ROFECOXIB; CHEMBL1084; UNII-8DJV9U9K61; 8DJV9U9K61; 2-hydroxy-3-(4-methylsulfonylphenyl)-4-phenyl-2H-furan-5-one; SCHEMBL6331980; CTK8F1097; DTXSID90433560; BDBM50094987; AKOS030240475; Rofecoxib metabolite 5-hydroxyrofecoxib; FT-0670222; J1.426.755G; J-011870; Q27270230; 2(5H)-Furanone, 5-hydroxy-4-(4-(methylsulfonyl)phenyl)-3-phenyl-; 5-Hydroxy-3-phenyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one; 5-Hydroxy-4-(4-methanesulfonyl-phenyl)-3-phenyl-5H-furan-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[104] | |||
| Compound Name |
6-(2,4-Dichlorophenyl)-5-(4-methylsulfonylphenyl)spiro[2.4]hept-5-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91258; SCHEMBL8383722; BDBM50049020; 6-[4-(Methylsulfonyl)phenyl]-5-(2,4-dichlorophenyl)spiro[2.4]hept-5-ene; 5-(2,4-Dichloro-phenyl)-6-(4-methanesulfonyl-phenyl)-spiro[2.4]hept-5-ene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[97] | |||
| Compound Name |
5-(3,4-Difluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-tetrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL366886; BDBM50286941
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
N-(4-Methylbenzyl)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL551830; BDBM50297676
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
4-[2-(4-Ethoxy-phenyl)-6-methanesulfonyl-pyrazolo[1,5-b]pyridazin-3-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL361494; BDBM50153995
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
6-[4-(Methylsulfonyl)phenyl]-5-[3,5-dichloro-4-methoxyphenyl]spiro[2.4]hept-5-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL315520; SCHEMBL213004; BDBM50049031; 5-(3,5-Dichloro-4-methoxy-phenyl)-6-(4-methanesulfonyl-phenyl)-spiro[2.4]hept-5-ene; 6-(3,5-dichloro-4-methoxyphenyl)-5-(4-methylsulfonylphenyl)spiro[2.4]hept-5-ene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[97] | |||
| Compound Name |
4-(4-Fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-2-phenoxypyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL556724; BDBM50297706
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
1-(2-(4-(4-(Methylsulfonyl)phenoxy)phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775095; BDBM50343908
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
N2-Cyclohexyl-6-(4-(methylsulfonyl)phenyl)pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL549927; BDBM50297656
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
4-[3-(3-Nitrophenyl)-5-propan-2-yl-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3937157; BDBM236636; US9388139, 3
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
Kazinol B
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL465371; MLS000697569; SCHEMBL3692685; CTK5I0571; DTXSID10244170; HMS2267O05; ZINC5854490; BDBM50250657; LMPK12020241; AKOS032948222; NCGC00247531-01; SMR000470924; 6-[(2S)-7-hydroxychroman-2-yl]-2,2-dimethyl-7-(3-methylbut-2-enyl)chromen-8-ol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
1-(2-(4-(4-Fluorophenoxy)phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775102; 1-[2-[4-(4-fluorophenoxy)phenoxy]ethyl]pyrrolidine; SCHEMBL7138014; BDBM50343915
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
2-(5-Bromopyridin-3-yl)-3-(4-methylsulfonylphenyl)cyclopent-2-en-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL24381; SCHEMBL8331164; BDBM50075654; 2-(5-Bromo-3-pyridyl)-3-[4-(methylsulfonyl)phenyl]-2-cyclopentene-1-one; 2-(5-Bromo-pyridin-3-yl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[65] | |||
| Compound Name |
8-Chloro-6-methyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288566; SCHEMBL215739; BDBM50331059; 8-chloro-6-methyl-2-trifluoromethyl-2H-1-benzopyran-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
1-(3,4-Difluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL298208; SCHEMBL7212139; BDBM50057892; 1-(3,4-Difluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole; 1-(3,4-difluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
5-[4-(Methylsulfonyl)phenyl]-6-(4-fluorophenyl)-1,3-benzodioxole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL298729; SCHEMBL6726405; BDBM50049650; 5-(4-fluorophenyl)-6-(4-methylsulfonylphenyl)-1,3-benzodioxole; 5-(4-Fluoro-phenyl)-6-(4-methanesulfonyl-phenyl)-benzo[1,3]dioxole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
1-(2-(4-(4-Bromophenoxy)phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775104; BDBM50343917
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
(2S)-6-Bromo-8-methyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3342574; CHEMBL3545849; SCHEMBL16893568; BDBM50030829
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[90] | |||
| Compound Name |
3-(4-Tert-butylanilino)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1682205; SCHEMBL13465068; BDBM50337286; ZINC66077713; 3-[N-(4-tert-butylphenyl)amino]benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[105] | |||
| Compound Name |
4-[3-(4-Bromophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410350; BDBM50074908
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
2-(3,3-Dimethyl-but-1-ynyl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL436539; BDBM50075659; 2-(3,3-Dimethyl-1-butynyl)-3-[4-(methylsulfonyl)phenyl]-2-cyclopentene-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[65] | |||
| Compound Name |
1-(4-Methanesulfonyl-phenyl)-2-phenyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL46637; SCHEMBL8811591; BDBM50057975
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
4-[4-Methoxy-5-phenyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29842; SCHEMBL6350037; BDBM50057530; 4-(4-Methoxy-5-phenyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide; 4-[3-(Trifluoromethyl)-4-methoxy-5-phenyl-1H-pyrazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
5-Chloro-3-(4-methanesulfonyl-phenyl)-5''-methyl-[2,3'']bipyridinyl
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL96947; BDBM50072057
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[59] | |||
| Compound Name |
N-(Cyclohexylmethyl)-4-(4-(methylsulfonyl)phenyl)-6-(trifluoromethyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL550473; BDBM50297667
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
N-[3-(3,5-Dichlorophenoxy)-4-pyridinyl]trifluoromethanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL225236; SCHEMBL4372692; BDBM50158454; N-[3-(3,5-dichlorophenoxy)pyridin-4-yl]-1,1,1-trifluoromethanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[112] | |||
| Compound Name |
N-[4-[5-(4-Fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]phenyl]methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL430728; SCHEMBL5698670; BDBM50057537; N-{4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-phenyl}-methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
4-[2-(4-Methylpyridin-3-yl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL326005; SCHEMBL5604642; BDBM50091210; 4-[2-(4-Methyl-pyridin-3-yl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
1-(4-Fluorophenyl)-4-formyl-5-methyl-2-(4-methylsulfonylphenyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL289813; SCHEMBL5308966; BDBM50057898; 1-(4-fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole-3-carbaldehyde; 1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrole-3-carbaldehyde; 1-(4-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole-3-carboxaldehyde
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
2-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-5-methyl-1H-pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL296307; CTK0A2867; DTXSID00445538; BDBM50057874; 2-(4-fluorophenyl)-5-methyl-1-(4-methylsulfonyl-phenyl)-1h pyrrole; 1H-Pyrrole, 2-(4-fluorophenyl)-5-methyl-1-[4-(methylsulfonyl)phenyl]-; 2-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole; 2-(4-Fluorophenyl)-5-methyl-1-(4-(methylsulfonyl)phenyl)-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
3-(4-Bromo-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL273815; BDBM50125631; 3-(4-Bromophenyl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[56] | |||
| Compound Name |
Loxoprofen
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-(4-((2-Oxocyclopentyl)methyl)phenyl)propanoic acid; Loxoprofene; Loxoprofeno; Koloxo; Loxoprofenum; sodium loxoprofen; Loxoprofen [INN]; 2-[4-[(2-oxocyclopentyl)methyl]phenyl]propanoic acid; UNII-3583H0GZAP; 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid; MFCD00864331; CHEMBL19299; 3583H0GZAP; Loxoprofen sodium hydrate; CS-600; Loxoprofen (INN); Oxeno; NCGC00015594-02; DSSTox_CID_25164; DSSTox_RID_80714; DSSTox_GSID_45164; Loxoprofene [French]; Loxoprofenum [Latin]; Loxoprofeno [Spanish]; yl]-propionic acid; 2-[4-(2-Oxo-cyclopentylmethyl)-phen; Loxoprofen, solid; Lopac0_000677; SCHEMBL24423; C15H17NaO3; (+-)-p-((2-Oxocyclopentyl)methyl)hydratropic acid; DTXSID1045164; CTK8B4007; alpha-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid; HMS3262G15; HMS3885N16; Loxoprofen (low-melting polymorph); BCP10971; EBD24378; HY-B0578; KS-00000GI6; Loxoprofen (high-melting polymorph); Tox21_110178; Tox21_500677; ANW-43655; BDBM50140320; s4682; AKOS015906359; Tox21_110178_1; AC-8108; AT-7141; CCG-204763; DB09212; GS-3193; LP00677; SDCCGSBI-0050656.P002; NCGC00015594-03; NCGC00015594-04; NCGC00015594-08; NCGC00094037-01; NCGC00094037-02; NCGC00261362-01; NCGC00263577-01; AC-15776; AK-72809; BR-72809; SC-46851; SY113439; AB0012364; DB-055188; EU-0100677; FT-0641207; L0244; CS-600; CS600; CS 600; D08149; L 0664; M-9376; (+-)-((2-oxocyclopentyl)methyl)hydratropic acid; 767L146; A836244; SR-01000075955; Q-201324; Q-300011; Q2759348; SR-01000075955-1; 2-[4-[(2-Oxocyclopentyl)methyl]phenyl]propionic Acid; 2-(4-((2-Oxocyclopentyl)methyl)-phenyl)propanoic acid; 2-[4-(2-Oxo-cyclopentylmethyl)-phenyl]-propionic acid; 2-[4-(2-oxocyclopentan-1-ylmethyl)phenyl]propionic acid; 2-[4-(2-Oxocyclopentan-1-ylmethyl)phenyl]-propionic Acid; 2-[4-[(2-oxidanylidenecyclopentyl)methyl]phenyl]propanoic acid; Benzeneacetic acid, alpha-methyl-4-((2-oxocyclopentyl)methyl)-; Benzeneacetic acid, .alpha.-methyl-4-[(2-oxocyclopentyl)methyl]-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[42] | |||
| Compound Name |
2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazole-4-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL415895; SCHEMBL5594017; BDBM50057949; 2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole-4-carbonitrile; 2-(4-Chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-1H-imidazole-4-carbonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
2-(4-Methylsulfinylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL296318; SCHEMBL8884942; BDBM50057920; 1-[4-(Methylsulfonyl)phenyl]-2-[4-(methylsulfinyl)phenyl]-4-(trifluoromethyl)-1H-imidazole; 2-(4-Methanesulfinyl-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
4-[5-(3,4-Dimethoxyphenyl)-3-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3926786; SCHEMBL12494300; BDBM236642; US9388139, 10
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
4-[5-Tert-butyl-3-(3,4-dichlorophenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3893185; SCHEMBL12524895; BDBM236644; US9388139, 13
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-(2-Chlorophenyl)-4-(2,5-difluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17126; SCHEMBL7840351; BDBM50076854; 2-(2-Chloro-phenyl)-4-(2,5-difluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775091; BDBM50343904
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
(R)-8-Propyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1289128; SCHEMBL5644933; BDBM50331079; (2r)-8-propyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-2h-chromene-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[68] | |||
| Compound Name |
4-(4-Cyano-5-p-tolyl-pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL28528; BDBM50057548; 4-[4-Cyano-5-(4-methylphenyl)-1H-pyrazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
2-(4-Chlorophenyl)-N,N-diethyl-1-(4-methylsulfonylphenyl)imidazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL291129; SCHEMBL8886642; BDBM50057916; 2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole-4-carboxylic acid diethylamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
5-(4-Fluoro-phenyl)-1-(4-sulfamoyl-phenyl)-1H-pyrazole-3-carboxylic acid amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29575; SCHEMBL6344501; BDBM50057543; 5-(4-fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
1-Butyl-2-(4-methanesulfonyl-phenyl)-5-methyl-1H-pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL297409; BDBM50057873
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
3-(4-Chloro-2-fluoro-phenyl)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL126979; BDBM50150203
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-Methyl-4-cyclopentyl-5-[4-(methylsulfonyl)phenyl]oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL350815; SCHEMBL8376294; BDBM50107523; 4-cyclopentyl-2-methyl-5-(4-methylsulfonylphenyl)-1,3-oxazole; 4-Cyclopentyl-5-(4-methanesulfonyl-phenyl)-2-methyl-oxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[62] | |||
| Compound Name |
2-Phenethyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL277385; SCHEMBL7834119; BDBM50076867; 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-phenethyl-thiazole; 4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-2-(2-phenylethyl)-1,3-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
2-Methyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL16850; SCHEMBL3242265; 4-(4-fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)-1,3-thiazole; BDBM50076875; 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-thiazole; 4-(4-Fluorophenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-thiazole; 4-(4-Fluorophenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)thiazole; 4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-2-methylthiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
4-[5-Tert-butyl-3-(4-hydroxyphenyl)-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3323320; SCHEMBL12523684; BDBM236638; US9388139, 5
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
2-Benzo[1,3]dioxol-4-yl-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL320790; BDBM50091207; 1-[4-(Methylsulfonyl)phenyl]-2-(1,3-benzodioxole-4-yl)-4-(trifluoromethyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
3-{4-[4-Chloro-1-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl]-2-fluorophenoxy}propyl Nitrate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL373819; BDBM50206928
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[96] | |||
| Compound Name |
1-(2-(4-(3-(Methylsulfonyl)phenoxy)phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775094; BDBM50343907
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
4-(3-Phenyl-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410338; BDBM50074848
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[60] | |||
| Compound Name |
2-(4-Fluoro-phenyl)-6-methanesulfonyl-3-(4-methanesulfonyl-phenyl)-pyrazolo[1,5-b]pyridazine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL434520; SCHEMBL5452506; BDBM50153986; 2-(4-fluorophenyl)-6-methylsulfonyl-3-(4-methylsulfonylphenyl)pyrazolo[1,5-b]pyridazine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
2-Methyl-1-(4-methylphenyl)-5-(4-methylsulfonylphenyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43737; SCHEMBL7212097; CTK0A2866; DTXSID50443241; BDBM50057902; 2-(4-Methanesulfonyl-phenyl)-5-methyl-1-p-tolyl-1H-pyrrole; 2-Methyl-5-(4-(methylsulfonyl)phenyl)-1-(p-tolyl)-1H-pyrrole; 1H-Pyrrole, 2-methyl-1-(4-methylphenyl)-5-[4-(methylsulfonyl)phenyl]-; 2-methyl-1-(4-methylphenyl)-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
3-{4-[1-(4-(Aminosulfonyl)phenyl)-4-chloro-1H-imidazol-5-yl]-2-fluorophenoxy}propyl Nitrate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL376246; BDBM50206927
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[96] | |||
| Compound Name |
3-[(3-Chlorophenoxy)methyl]-1-(4-fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43736; SCHEMBL7215484; BDBM50057900; 3-(3-Chloro-phenoxymethyl)-1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrole; 3-[(3-chlorophenoxy)methyl]-1-(4-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole; 3-[(3-Chlorophenoxy)methyl]-2-methyl-1-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
4-[3-(Trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL285831; SCHEMBL3096416; BDBM50057568; 4-(3-(trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)-1H-pyrazol-1-yl)benzenesulfonamide; 4-[3-(Trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]-1H-pyrazole-1-yl]benzenesulfonamide; 4-[3-Trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazol-1-yl]-benzenesulfonamide; 4-[5-(4-trifluoromethylphenyl)-3-(trifluoromet-hyl)-1h-pyrazol-1-yl]benzenesulfonamide; 4-[5-(4-trifluoromethylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
2-Chloro-1-methoxy-4-[2-(4-methylsulfonylphenyl)phenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL299567; SCHEMBL6724132; BDBM50049638; ZINC13755785; 2-chloro-1-methoxy-4-[2-[4-(methylsulfonyl)phenyl]phenyl]benzene; 3''-Chloro-4''-methoxy-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 3-Chloro-4''''-methanesulfonyl-4-methoxy-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
1-(2-(4-(3-Nitrophenoxy)phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775088; BDBM50343926
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
2-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-1H-pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43957; 2-(4-fluorophenyl)-1-(4-methylsulfonylphenyl)pyrrole; SCHEMBL5314063; BDBM50057905; 2-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-pyrrole; 2-(4-fluorophenyl)-1-[4-(methylsulfonyl) phenyl]-1h-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
4-(4-Hydroxy-5-phenyl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL282752; BDBM50057556; 4-[3-(Trifluoromethyl)-4-hydroxy-5-phenyl-1H-pyrazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
2-(2,2,2-Trifluoroethoxy)-3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL48671; BDBM50078585; 3-(4-Methanesulfonyl-phenyl)-2-(2,2,2-trifluoro-ethoxy)-5-trifluoromethyl-pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[81] | |||
| Compound Name |
2-(3-Benzoyl-5-ethyl-phenyl)-ethenesulfonic acid amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL151128; SCHEMBL13981212; BDBM50109715; LM-1669
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[122] | |||
| Compound Name |
2-(5-Chloro-pyridin-3-yl)-3-(4-methanesulfonyl-phenyl)-cyclopent-2-enone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL286490; SCHEMBL8325050; BDBM50075652; 2-(5-chloropyridin-3-yl)-3-(4-methylsulfonylphenyl)cyclopent-2-en-1-one; 2-(5-Chloro-3-pyridinyl)-3-(4-(methylsulfonyl)phenyl)-2-cyclopenten-1-one; 2-(5-Chloro-3-pyridyl)-3-[4-(methylsulfonyl)phenyl]-2-cyclopentene-1-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[65] | |||
| Compound Name |
6,8-Dimethoxy-3-(3'',5''-dimethoxyphenyl)coumarin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL378382; BDBM50176524
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[67] | |||
| Compound Name |
4-[5-Pyridin-3-yl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL406140; SCHEMBL6339092; BDBM50057557; 4-(5-Pyridin-3-yl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
1-(4-Methylsulfonylphenyl)-2-thiophen-3-yl-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL321898; SCHEMBL3252855; BDBM50091195; 1-(4-Methanesulfonyl-phenyl)-2-thiophen-3-yl-4-trifluoromethyl-1H-imidazole; 1-[4-(Methylsulfonyl)phenyl]-2-(3-thienyl)-4-(trifluoromethyl)-1H-imidazole; 3-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1h-imidazol-2-yl]thiophene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
1-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL340458; SCHEMBL5698518; BDBM50037943; ZINC13739713; 1-methylsulfonyl-4-(2-phenylcyclopenten-1-yl)benzene; 1-Methanesulfonyl-4-(2-phenyl-cyclopent-1-enyl)-benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
4-[2-(2-Chlorophenyl)-4-(3-fluoro-4-methoxyphenyl)-5-thiazolyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL276762; SCHEMBL7841503; BDBM50076879; 4-[2-(2-Chloro-phenyl)-4-(3-fluoro-4-methoxy-phenyl)-thiazol-5-yl]-benzenesulfonamide; 4-[2-(2-chlorophenyl)-4-(3-fluoro-4-methoxyphenyl)-1,3-thiazol-5-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[74] | |||
| Compound Name |
2-(2-Thienyl)-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL16689; SCHEMBL213502; BDBM50076851; 4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-2-thiophen-2-yl-1,3-thiazole; 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-thiophen-2-yl-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
4-[5-(3-Chloro-4-methoxy-5-methyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29844; SCHEMBL6340657; BDBM50057522; 4-[5-(3-chloro-4-methoxy-5-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide; 4-[3-(Trifluoromethyl)-5-(3-chloro-4-methoxy-5-methylphenyl)-1H-pyrazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
1-(4-Chlorophenyl)-2-(4-methylsulfonylphenyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55188; SCHEMBL6725659; BDBM50049629; ZINC13755783; 1-(4-chlorophenyl)-2-[4-(methylsulfonyl)phenyl]benzene; 4''-Chloro-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 4''''-Chloro-4-methanesulfonyl-[1,1'';2'',1'''']terphenyl; 4-Chloro-4''''-methanesulfonyl-[1,1'';2'',1'''']terphenyl; 4''''''''-Chloro-4-methanesulfonyl-[1,1'''';2'''',1'''''''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
4-[1-(4-Methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]pyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL420479; SCHEMBL3241987; BDBM50091175; 4-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-pyridine; 4-[1-[4-(methylsulfonyl)phenyl]-4-trifluoromethyl-1h-imidazol-2-yl]pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
1-(2-(4-(4-Chlorophenoxy)phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775103; BDBM50343916
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
Sodium;(4R,5S)-6-hydroxy-5-(4-methylsulfonylphenyl)-4-phenylhexanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL327468
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[104] | |||
| Compound Name |
US9271961, Bmt 3-224
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3973623; BDBM220122
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[105] | |||
| Compound Name |
3-(4-Acetylanilino)benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1682201; 3-[(4-acetylphenyl)amino]benzoic Acid; SCHEMBL5460527; BDBM50337282; ZINC38340145; 3-[(4-acetylphenyl)amino]benzoicacid; AKOS022842910; MCULE-5116371655; 3-[N-(4-acetylphenyl)amino]benzoic acid; AN-584/43462959
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[105] | |||
| Compound Name |
3-Cyclohexyl-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL265071; SCHEMBL6967130; BDBM50150187; 3-Cyclohexyl-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
3-Cyclohexyl-4-(4-sulfamoylphenyl)-4-oxazoline-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL432335; BDBM50084354; 4-(3-Cyclohexyl-2-oxo-2,3-dihydro-oxazol-4-yl)-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[108] | |||
| Compound Name |
N-[(E)-(4-Chloro-2-oxochromen-3-yl)methylideneamino]-5-phenyl-1-(4-sulfamoylphenyl)pyrazole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3822753; BDBM50185917
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[48] | |||
| Compound Name |
[1-(4-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrol-3-yl]methyl Acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL294971; SCHEMBL7210588; BDBM50057901; [1-(4-fluorophenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrol-3-yl]methyl acetate; Acetic acid 1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrol-3-ylmethyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
4-[5-(2-Methoxyphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29942; SCHEMBL6014008; BDBM50057555; 4-[5-(2-Methoxy-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide; 4-[3-(Trifluoromethyl)-5-(2-methoxyphenyl)-1H-pyrazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
[1-[4-[5-Chloro-3-(4-methylsulfonylphenyl)imidazol-4-yl]-2-fluorophenoxy]-3-nitrooxypropan-2-yl] nitrate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL373867; BDBM50206931
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[96] | |||
| Compound Name |
1-(4-Fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)-3-(2,2,2-trifluoroethyl)pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44038; SCHEMBL7215422; BDBM50057884; 1-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-3-(2,2,2-trifluoro-ethyl)-1H-pyrrole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
1-(2-(4-(3-(Trifluoromethyl)phenoxy)phenoxy)ethyl)pyrrolidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775100; BDBM50343913
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
2-(4-Chlorophenyl)-4-(methylsulfanylmethyl)-1-(4-methylsulfonylphenyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43933; SCHEMBL5594277; BDBM50057951; 2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4-methylsulfanylmethyl-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
1,1-Diphenyl-2-(4-mesylphenyl)-1-hexene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1221731; BDBM50324804; (2-(4-(methylsulfonyl)phenyl)hex-1-ene-1,1-diyl)dibenzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[123] | |||
| Compound Name |
{2,6-Dichloro-4-[1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-phenyl}-dimethyl-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43553; BDBM50057957
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
3-[(4-Bromophenyl)Amino]Benzoic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1682204; 3-(4-bromoanilino)benzoic acid; SCHEMBL13280274; BDBM50337285; ZINC66098454; 3-[N-(4-bromophenyl)amino]benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[105] | |||
| Compound Name |
4-(4-Fluorophenyl)-5-(4-(methylsulfonyl)phenyl)isothiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL171646; SCHEMBL7619479; BDBM50240911; AKOS000279328; 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-isothiazole; 4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-1,2-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
N-(4-Aminopyridin-2-yl)-3-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL258656; BDBM50376382
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
1,3-Dichloro-5-[4,5-difluoro-2-(4-methylsulfonylphenyl)phenyl]-2-methoxybenzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55224; SCHEMBL6728961; BDBM50049648; 3'',5''-Dichloro-4',5'-difluoro-4''-methoxy-4-(methylsulfonyl)-1,1':2',1''-terbenzene; 3,5-Dichloro-4'',5''-difluoro-4''''-methanesulfonyl-4-methoxy-[1,1'';2'',1'''']terphenyl
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
(2R,3S,4S,5S,6R)-6-[[5-[5-Chloro-3-(4-methylsulfonylphenyl)pyridin-2-yl]pyridin-2-yl]methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2303835; BDBM50451344
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[110] | |||
| Compound Name |
4-[3-(4-Bromophenyl)-5-tert-butyl-3,4-dihydropyrazol-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3908967; SCHEMBL12495713; BDBM236655; US9388139, 24
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
1-(4-Benzenesulfonyl-phenyl)-2-(4-fluoro-phenyl)-1H-pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42120; BDBM50057897
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
3-[2-Oxo-4-(4-sulfamoyl-phenyl)-oxazol-3-yl]-benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL72093; BDBM50084357
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[108] | |||
| Compound Name |
4-(4-Fluorophenyl)-5-(4-methylsulfonylphenyl)-2-phenylthiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL442063; SCHEMBL7832424; BDBM50076871; 2-Phenyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole; 4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-phenyl-thiazole; 4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-2-phenyl-1,3-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
N-Cyclohexyl-4-methyl-6-(4-(methylsulfonyl)phenyl)pyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL540166; BDBM50297659
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2-Tert-Butyl-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17064; SCHEMBL7833896; BDBM50076852; 2-tert-Butyl-4-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazole; 2-tert-butyl-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-1,3-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
2-(2-Chlorophenyl)-4-(2-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL279552; SCHEMBL7832608; BDBM50076868; 2-(2-Chloro-phenyl)-4-(2-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazole; 2-(2-chlorophenyl)-4-(2-fluorophenyl)-5-(4-methylsulfonylphenyl)-1,3-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
(3R,4S)-4-(4-Methanesulfonyl-phenyl)-3-phenyl-dihydro-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL89392; cis-3',4'-Dihydrorofecoxib; BDBM50094988; UNII-2VL6DH29WP component PHCFUFKRCHEUTJ-CVEARBPZSA-N
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[104] | |||
| Compound Name |
3-(5-Chlorofuran-2-yl)-5-phenyl-1,2-oxazole-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2380878; SCHEMBL2279814; BDBM50491541
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[89] | |||
| Compound Name |
2-[4-(Methylsulfonyl)phenyl]-3-(4-fluorophenyl)naphthalene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL294650; BDBM50049658; 2-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-naphthalene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
N-[6-(4-Methyl-thiazol-2-ylsulfanyl)-1-oxo-indan-5-yl]-methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL37414; BDBM50073866; N-[6-[(4-methyl-1,3-thiazol-2-yl)sulfanyl]-1-oxo-2,3-dihydroinden-5-yl]methanesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
4-[(4-Chlorophenoxy)methyl]-2-(4-chlorophenyl)-1-(4-methylsulfonylphenyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL441236; 2-(4-chlorophenyl)-1-(4-(methylsulfonyl)phenyl]-4-((4-chlorophenoxy)methyl]-1H-imidazole; 2-(4-chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-4-[(4-chlorophenoxy)methyl]-1H-imidazole; SCHEMBL3243097; BDBM50057976; 4-(4-Chloro-phenoxymethyl)-2-(4-chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
3-{4-[4-Chloro-1-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl]-2-fluorophenoxy}propan-1-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219885; BDBM50206932
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[96] | |||
| Compound Name |
3-((4-(Trifluoromethyl)Phenyl)Amino)Benzoic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-{[4-(Trifluoromethyl)phenyl]amino}benzoic Acid; CHEMBL1682202; 3-[4-(trifluoromethyl)anilino]benzoic acid; SCHEMBL13279924; HMS3743G11; BDBM50337283; MFCD28016823; ZINC54186689; AKOS011941571; 3-[(4-Trifluoromethylphenyl)Amino]Benzoic Acid; 3-[N-(4-trifluoromethylphenyl)amino]benzoic acid; Q27458541
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[105] | |||
| Compound Name |
2-Methyl-4-phenyl-5-[4-(methylsulfonyl)phenyl]-4-isoxazoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL442760; BDBM50103309; 5-(4-Methanesulfonyl-phenyl)-2-methyl-4-phenyl-2,3-dihydro-isoxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[116] | |||
| Compound Name |
3-(4-Acetoxyphenyl)-4-[4-(methylsulfonyl)phenyl]-2,5-dihydrofuran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL93372; BDBM50118683; Acetic acid 4-[4-(4-methanesulfonyl-phenyl)-2-oxo-2,5-dihydro-furan-3-yl]-phenyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[114] | |||
| Compound Name |
4-[3-(3-Chloro-2,4,6-trimethoxy-phenyl)-5-methyl-isoxazol-4-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL186817; BDBM50153039
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[94] | |||
| Compound Name |
1-[4-[2-Methyl-5-(4-methylsulfonylphenyl)pyrrol-1-yl]phenyl]ethanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL297820; SCHEMBL7216271; BDBM50057867; 1-{4-[2-(4-Methanesulfonyl-phenyl)-5-methyl-pyrrol-1-yl]-phenyl}-ethanone; 1-[4-[2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrol-1-yl]phenyl]ethanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
2-(4-Fluorobenzyl)-4-(4-fluorophenyl)-5-(4-(methylsulfonyl)phenyl)pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL559952; BDBM50297701
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
N-[3-(3,5-Dichlorophenoxy)-4-pyridinyl]methanesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL390317; CTK3D2872; DTXSID70461765; BDBM50158455; Methanesulfonamide, N-[3-(3,5-dichlorophenoxy)-4-pyridinyl]-
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[112] | |||
| Compound Name |
2-[5-Methoxy-2-(4-methylpyridine-2-carbonyl)-1H-indol-3-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1950018; SCHEMBL6169808; BDBM50365166
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[118] | |||
| Compound Name |
2-[2-(4-Ethylpyridine-2-carbonyl)-5-(trifluoromethoxy)-1H-indol-3-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1950015; SCHEMBL6168900; BDBM50365163
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[118] | |||
| Compound Name |
2-[2-(4-Methylpyridine-2-carbonyl)-5-(trifluoromethoxy)-1H-indol-3-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1950014; SCHEMBL6169141; BDBM50365162
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[118] | |||
| Compound Name |
[2-(4-Chlorophenyl)-1-(4-methylsulfonylphenyl)imidazol-4-yl]methanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL45383; SCHEMBL5594584; BDBM50057923; 1-[4-(Methylsulfonyl)phenyl]-2-(4-chlorophenyl)-1H-imidazole-4-methanol; 2-(4-Chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-1H- imidazole-4 -methanol; 2-(4-chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-1H-imidazole-4-methanol; [2-(4-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazol-4-yl]-methanol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
4-(4-Fluorophenyl)-5-(4-(methylsulfonyl)phenyl)-N-phenylpyrimidin-2-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL564962; BDBM50297697
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[46] | |||
| Compound Name |
2-[4,5-Difluoro-2-(4-methylsulfonylphenyl)phenyl]-5-methylpyridine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL292607; SCHEMBL6726456; BDBM50049626; 2-(4,5-Difluoro-4''-methanesulfonyl-biphenyl-2-yl)-5-methyl-pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
4-(4-Fluoro-phenyl)-3-(4-methanesulfonyl-phenyl)-1-phenethyl-1H-pyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL67519; SCHEMBL216154; BDBM50289976; 4-(4-fluorophenyl)-3-(4-methylsulfonylphenyl)-1-(2-phenylethyl)pyrazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[100] | |||
| Compound Name |
6-(4-Fluorophenyl)-7-[4-(methylsulfonyl)phenyl]spiro[3.4]oct-6-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL90447; SCHEMBL215233; BDBM50049022; 6-(4-fluorophenyl)-7-(4-methylsulfonylphenyl)spiro[3.4]oct-6-ene; 6-(4-Fluoro-phenyl)-7-(4-methanesulfonyl-phenyl)-spiro[3.4]oct-6-ene; 6-(4-fluorophenyl)-7-[4-(methylsulfonyl)phenyl]spiro[ 3.4]oct-6-ene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
4-(4-Fluorophenyl)-5-[4-(methylsulfonyl)phenyl]thiazole-2-acetonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL417266; SCHEMBL7832463; BDBM50076876; [4-(4-Fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-thiazol-2-yl]-acetonitrile; 2-[4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-1,3-thiazol-2-yl]acetonitrile
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
Benzenesulfonamide, p-((p-(dimethylamino)phenyl)azo)-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS001171151; CHEMBL277836; 4-[[4-(dimethylamino)phenyl]diazenyl]benzenesulfonamide; SMR000592529; BRN 0677712; 4-((4-(Dimethylamino)Phenyl)Diazenyl)Benzenesulfonamide; 4-Sulfonamide-4'-dimethylaminoazobenzene; azo-sulfonamide, 1d; 4-{(e)-[4-(dimethylamino)phenyl]diazenyl}benzenesulfonamide; SCHEMBL42643; 3-16-00-00372 (Beilstein Handbook Reference); cid_75522; p-Phenyldiazenyl derivative, 4; CHEMBL1459709; BDBM33269; CTK8D3164; HMS2915K03; ZINC17857672; AKOS034461621; MCULE-4325588575; NCGC00246044-01; 4'-(Dimethylamino)azobenzene-4-sulfonamide; SR-01000036097; SR-01000817680; 4-(4'-Dimethylaminophenyl)Diazenylbenzenesulfonamide; 4-[[4-(dimethylamino)phenyl]azo]benzenesulfonamide; SR-01000036097-1; SR-01000817680-2; 4-[(E)-(4-dimethylaminophenyl)azo]benzenesulfonamide; Z56857031; 4-(e)-[4-(dimethylamino)phenyl]diazenylbenzenesulfonamide; 4-{2-[4-(dimethylamino)phenyl]diazen-1-yl}benzene-1-sulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[24] | |||
| Compound Name |
4-[5-(4-Chlorophenyl)-3-(5-chlorothiophen-2-yl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL283633; SCHEMBL215007; BDBM50057533; 4-[5-(4-Chloro-phenyl)-3-(5-chloro-thiophen-2-yl)-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
4-[4,5-Difluoro-2-(5-methylpyridin-2-yl)phenyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL54619; SCHEMBL6250610; BDBM50049620; 4'',5''-Difluoro-2''-(5-methyl-pyridin-2-yl)-biphenyl-4-sulfonic acid amide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[88] | |||
| Compound Name |
Pyridine,2-methyl-3-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1h-imidazol-2-yl]-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL110574; SCHEMBL5594051; BDBM50091173; ZINC13812814; 2-methyl-3-[1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazol-2-yl]pyridine; 2-methyl-3-[1-[4-(methylsulfonyl)phenyl]-4(trifluoromethyl)-1H-imidazol-2-yl]pyridine; 2-methyl-3-[1-[4-(methylsulfonyl)phenyl]-4-(trifluoromethyl)-1H-imidazol-2-yl]pyridine; 3-[1-(4-Methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazol-2-yl]-2-methyl-pyridine
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[53] | |||
| Compound Name |
4-[5-(3-Fluorophenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29620; SCHEMBL6343096; BDBM50057616; 4-[5-(3-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide; 4-[3-(Trifluoromethyl)-5-(3-fluorophenyl)-1H-pyrazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
Morusin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Mulberrochromene; TCMDC-124149; UNII-T4VGD5NP9B; NSC649220; T4VGD5NP9B; CHEMBL464006; Morusin, 3; NSC 649220; MLS000697591; MEGxp0_001039; SCHEMBL2562778; ACon1_001205; cid_5281671; DTXSID70211641; HMS2271K05; BCP16494; HY-N0622; ZINC5195808; BDBM50242014; LMPK12110912; MFCD09953814; AKOS032962066; CS-6885; NSC-649220; AK169967; SMR000470930; FT-0686661; N2266; W1523; A14647; C10106; BRD-K40169295-001-01-2; Q27107393
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[7] | |||
| Compound Name |
4-[5-Tert-butyl-3-(4-fluorophenyl)-3,4-dihydropyrazol-2-yl]benzenesulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3921118; SCHEMBL12524133; BDBM236656; US9388139, 25
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[13] | |||
| Compound Name |
5-Amino-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630234; SCHEMBL5647705; BDBM50332746
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[70] | |||
| Compound Name |
2-(4-(2-(Pyrrolidin-1-yl)ethoxy)phenoxy)aniline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1775105; BDBM50343918
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[64] | |||
| Compound Name |
1-(4-Ethanesulfonyl-phenyl)-2-(4-fluoro-phenyl)-1H-pyrrole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42121; BDBM50057872
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
2-(2-Chlorophenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL289169; SCHEMBL5594518; BDBM50057927; 2-(2-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[49] | |||
| Compound Name |
1-[2-[4-(Methylsulfonyl)phenyl]-1-cyclopentenyl]-2-methyl-4-fluorobenzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL321182; SCHEMBL213291; ZINC3814642; BDBM50037940; 4-[2-(4-fluoro-2-methylphenyl)cyclopent-1-en-1-yl]phenyl methyl sulfone; 4-fluoro-2-methyl-1-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]benzene; 4-Fluoro-1-[2-(4-methanesulfonyl-phenyl)-cyclopent-1-enyl]-2-methyl-benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[58] | |||
| Compound Name |
2-Methyl-4-cyclohexyl-5-[4-(methylsulfonyl)phenyl]oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL161677; SCHEMBL8376304; 4-cyclohexyl-2-methyl-5-(4-methylsulfonylphenyl)-1,3-oxazole; BDBM50107519; 4-Cyclohexyl-5-(4-methanesulfonyl-phenyl)-2-methyl-oxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[62] | |||
| Compound Name |
3-(4-Amino-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL338347; BDBM50150196
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[4] | |||
| Compound Name |
2-(2-Chlorophenyl)-4-phenyl-5-[4-(methylsulfonyl)phenyl]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL443993; SCHEMBL5698703; BDBM50076866; 2-(2-Chloro-phenyl)-5-(4-methanesulfonyl-phenyl)-4-phenyl-thiazole; 2-(2-chlorophenyl)-5-(4-methylsulfonylphenyl)-4-phenyl-1,3-thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[71] | |||
| Compound Name |
6-(3,4-Dichlorophenyl)-5-(4-methylsulfonylphenyl)spiro[2.4]hept-5-ene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL558340; SCHEMBL8385166; BDBM50049018; 6-[4-(Methylsulfonyl)phenyl]-5-[3,4-dichlorophenyl]spiro[2.4]hept-5-ene; 5-(3,4-Dichloro-phenyl)-6-(4-methanesulfonyl-phenyl)-spiro[2.4]hept-5-ene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[97] | |||
| Compound Name |
5-(4-Fluorophenyl)-1-(4-sulfamoylphenyl)pyrazole-3-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29943; SCHEMBL5698710; BDBM50057534; 5-(4-Fluoro-phenyl)-1-(4-sulfamoyl-phenyl)-1H-pyrazole-3-carboxylic acid; [1-(4-aminosulfonylphenyl)-5-(4-fluorophenyl)-1h-pyrazol-3-yl]carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[45] | |||
| Compound Name |
3-[4-(Trifluoromethyl)phenyl]-4-[4-(methylsulfonyl)phenyl]-4-oxazoline-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL307233; SCHEMBL8394966; BDBM50084343; 4-(4-methylsulfonylphenyl)-3-[4-(trifluoromethyl)phenyl]-1,3-oxazol-2-one; 4-(4-Methanesulfonyl-phenyl)-3-(4-trifluoromethyl-phenyl)-3H-oxazol-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[108] | |||
| Compound Name |
2,2,2-Trifluoro-1-[1-(4-fluoro-phenyl)-5-(4-methanesulfonyl-phenyl)-2-methyl-1H-pyrrol-3-yl]-ethanol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44362; SCHEMBL7215275; BDBM50057883
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[92] | |||
| Compound Name |
N-(4-Aminophenyl)-2-(trifluoromethyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL408808; SCHEMBL678924; CTK7D7677; BDBM50376391; AKOS000133138; N-(4-Aminophenyl)-2-trifluoromethyl-benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[66] | |||
| Compound Name |
4-[2-(3-Fluoro-4-(trifluoromethyl)phenyl)-1-cyclopentenyl]-1-(methylsulfonyl)benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL323732; SCHEMBL8652972; BDBM50029608; 2-Fluoro-4-[2-(4-methanesulfonyl-phenyl)-cyclopent-1-enyl]-1-trifluoromethyl-benzene; 2-fluoro-4-[2-(4-methylsulfonylphenyl)cyclopenten-1-yl]-1-(trifluoromethyl)benzene; 2-fluoro-4-{2-[4-(methylsulfonyl)phenyl]cyclopent-1-en-1-yl}-1-(trifluoromethyl)benzene
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[73] | |||
| Compound Name |
Rofecoxib-threo-3,4-dihydrohydroxy acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL313048; UNII-N7Q5T51WVF; N7Q5T51WVF; BDBM50094989; J1.431.852F; Q27284676; Rofecoxib metabolite rofecoxib-threo-3,4-dihydrohydroxy acid; (2S,3S)-2-Phenyl-3-[4-(methylsulfonyl)phenyl]-4-hydroxybutanoic acid; (2S,3S)-4-Hydroxy-3-(4-methanesulfonyl-phenyl)-2-phenyl-butyric acid; Rac-(2S*,3S*)-2-phenyl-3-(4-(methylsulfonyl)phenyl)-4-hydroxybutanoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[104] | |||
| Compound Name |
2-Methyl-4-(5-ethyl-2-thienyl)-5-[4-(methylsulfonyl)phenyl]oxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL345620; BDBM50107529; 4-(5-Ethyl-thiophen-2-yl)-5-(4-methanesulfonyl-phenyl)-2-methyl-oxazole
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[62] | |||
| Compound Name |
4-[3-(3-Bromophenyl)-3,3a,4,5-tetrahydrobenzo[g]indazol-2-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3410349; BDBM50074907
Click to Show/Hide
|
||||
| Activity |
IC50 = 100200 nM
|
[60] | |||
| Compound Name |
2-(Benzenesulfonyl)-3-(2,3-dihydro-1,4-benzodioxin-5-yl)-5-(trifluoromethyl)-3,4-dihydropyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3309825; BDBM50045707
Click to Show/Hide
|
||||
| Activity |
IC50 = 100300 nM
|
[57] | |||
| Compound Name |
2-[[1-(2-Chloropyridin-3-yl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264704; BDBM50016430
Click to Show/Hide
|
||||
| Activity |
IC50 = 102660 nM
|
[80] | |||
| Compound Name |
2-[[1-(3-Nitrophenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264687; BDBM50016439
Click to Show/Hide
|
||||
| Activity |
IC50 = 103520 nM
|
[80] | |||
| Compound Name |
Chembl4169347
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
GTPL9684; BDBM50279050; compound 12a [PMID: 29031075]; 9-(4-chlorobenzoyl)-6-(methylsulfonyl)-1,2,3,9-tetrahydro-4h-carbazol-4-one; 9-(4-chlorobenzoyl)-6-methanesulfonyl-2,3,4,9-tetrahydro-1H-carbazol-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 104000 nM
|
[11] | |||
| Compound Name |
3-(3,5-Dimethoxyphenyl)-7-hydroxy-2H-1-benzopyran-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL199788; CTK3C4457; DTXSID60658768; BDBM50176528; 3-(3,5-Dimethoxyphenyl)-7-hydroxycoumarin; 3-(3,5-dimethoxyphenyl)-7-hydroxy-2H-chromen-2-one; 2H-1-Benzopyran-2-one, 3-(3,5-dimethoxyphenyl)-7-hydroxy-
Click to Show/Hide
|
||||
| Activity |
IC50 = 105000 nM
|
[67] | |||
| Compound Name |
3-(4-Chlorophenyl)-5-hydroxy-5-methyl-4-(4-methylsulfonylphenyl)furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL275664; SCHEMBL7842927; BDBM50125624; 3-(4-Chloro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one; 3-(4-Chlorophenyl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 105000 nM
|
[56] | |||
| Compound Name |
2-(Benzenesulfonyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(trifluoromethyl)-3,4-dihydropyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3309823; BDBM50045635
Click to Show/Hide
|
||||
| Activity |
IC50 = 105600 nM
|
[57] | |||
| Compound Name |
2-[(1-Phenyltriazol-4-yl)methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264689; BDBM50016441
Click to Show/Hide
|
||||
| Activity |
IC50 = 107250 nM
|
[80] | |||
| Compound Name |
4-[(3,5-Dimethoxy-benzylidene)-amino]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL271561; NSC720515; CTK6J4937; BDBM50371743; NSC-720515; NCI60_041288; 4-{[(e)-(3,5-dimethoxyphenyl)methylidene]amino}benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 109690 nM
|
[20] | |||
| Compound Name |
2-(6-Chloro-9H-carbazol-2-yl)-propionic acid 2-nitrooxy-ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL497678; BDBM50272678
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[1] | |||
| Compound Name |
4-[(3,4-Dimethoxy-benzylidene)-amino]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL271832; NSC720518; CTK7A7215; ZINC1663216; BDBM50371750; AKOS002313789; MCULE-4302728307; NSC-720518; ST50758972; 4-[(3,4-Dimethoxybenzylidene)amino]benzenesulfonamide; 4-[(1E)-2-(3,4-dimethoxyphenyl)-1-azavinyl]benzenesulfonamide; 4-{[(e)-(3,4-dimethoxyphenyl)methylene]amino}benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 110270 nM
|
[20] | |||
| Compound Name |
5-Chloro-3-[[1-(4-chlorophenyl)triazol-4-yl]methyl]-1,3-benzoxazol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3087875; BDBM50494436
Click to Show/Hide
|
||||
| Activity |
IC50 = 111340 nM
|
[124] | |||
| Compound Name |
2-(2,4-Dichlorophenoxy)-N-[(E)-[3-(4-ethylphenyl)-4-oxo-1,3-thiazolidin-2-ylidene]amino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4070457; BDBM50235072
Click to Show/Hide
|
||||
| Activity |
IC50 = 113120 nM
|
[86] | |||
| Compound Name |
6-Cyano-2-(trifluoromethyl)-2H-1-benzopyran-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288564; 6-cyano-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid; SCHEMBL6092946; BDBM50331056
Click to Show/Hide
|
||||
| Activity |
IC50 = 115000 nM
|
[68] | |||
| Compound Name |
4-[2-Methyl-5-(4-bromophenyl)-4-thiazolyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL280093; SCHEMBL7840067; BDBM50076885; 4-[5-(4-Bromo-phenyl)-2-methyl-thiazol-4-yl]-benzenesulfonamide; 4-[5-(4-bromophenyl)-2-methyl-1,3-thiazol-4-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 115000 nM
|
[74] | |||
| Compound Name |
2-[[1-(4-Nitrophenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264688; BDBM50016440
Click to Show/Hide
|
||||
| Activity |
IC50 = 115230 nM
|
[80] | |||
| Compound Name |
(1R,4Ar,7S)-7-ethenyl-1,4a,7-trimethyl-3,4,6,8,8a,9,10,10a-octahydro-2H-phenanthrene-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL152325; SCHEMBL12450150; BDBM50097211
Click to Show/Hide
|
||||
| Activity |
IC50 = 116400 nM
|
[47] | |||
| Compound Name |
N-[(2S)-2-(3,4-Dihydroxyphenyl)-2-[(2R)-2,3-dihydroxypropoxy]ethyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3338324; BDBM50035606
Click to Show/Hide
|
||||
| Activity |
IC50 = 117000 nM
|
[125] | |||
| Compound Name |
2-Methyl-3-(2-chlorobenzyl)-6-(methylsulfonyl)-1H-indole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL363756; SCHEMBL5102759; 3-[(2-chlorophenyl)methyl]-2-methyl-6-methylsulfonyl-1H-indole; BDBM50151758; 3-(2-Chloro-benzyl)-6-methanesulfonyl-2-methyl-1H-indole
Click to Show/Hide
|
||||
| Activity |
IC50 = 118000 nM
|
[54] | |||
| Compound Name |
Chembl4173526
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50279037
Click to Show/Hide
|
||||
| Activity |
IC50 = 118000 nM
|
[11] | |||
| Compound Name |
N-(3',4'-Dichloro[1,1'-biphenyl]-4-yl)-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
pf-9184; CHEMBL1087267; C21H14Cl2N2O4S; AOB4734; SYN5102; BDBM50313205; AKOS027470312; ZINC101331153; PF 9184; NCGC00402263-03; AS-16466; HY-19622; CS-0015995; FT-0699578
Click to Show/Hide
|
||||
| Activity |
IC50 = 118000 nM
|
[35] | |||
| Compound Name |
3-(4-Bromophenoxy)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127514; SCHEMBL1378064; BDBM50150222; 3-(4-Bromo-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 119000 nM
|
[4] | |||
| Compound Name |
Chembl4177185
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50279039
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[11] | |||
| Compound Name |
2-(6-Chloro-9H-carbazol-2-yl)-propionic acid 2-nitrooxy-propyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL498529; BDBM50272734
Click to Show/Hide
|
||||
| Activity |
IC50 = 123000 nM
|
[1] | |||
| Compound Name |
3-(4-Fluoro-phenylsulfanyl)-6-methanesulfonyl-1H-indole-2-carbonitrile
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL433585; SCHEMBL5116387; 3-(4-fluorophenyl)sulfanyl-6-methylsulfonyl-1H-indole-2-carbonitrile; BDBM50151771
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 125000 nM
|
[54] | |||
| Compound Name |
2-Methyl-5-[4-(methylsulfonyl)phenyl]-1-[3-(fluoro)phenyl]-1H-pyrrol-3-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL589167; SCHEMBL3830979; BDBM50308735
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[126] | |||
| Compound Name |
Fangchinoline
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(+)-Fangchinoline; (+)-Limacine; 7-O-Demethyltetrandrine; Menisidine; UNII-953592C3ZB; NSC77036; MLS000728580; CHEMBL504256; NSC-77036; 953592C3ZB; SMR000445631; Limacine; Hanfangchin B; NSC 77036; Fangchinoline (6CI,7CI,8CI); (1-beta)-2,2'-Dimethyl-6,6',12-trimethoxyberbaman-7-ol; 12-O-Methylatherospermoline; SCHEMBL1460487; HY-N1372A; DTXSID40893498; Fangchinoline, >=98% (HPLC); HMS2226P12; HMS3885G15; Berbaman-7-ol, 2,2'-dimethyl-6,6',12-trimethoxy-, (1-beta)-; BDBM50241651; s3611; ZINC38148193; AKOS015915280; CCG-270220; EBD2184727; NCGC00247556-01; NCI60_041695; CS-0008917; A14557; SR-01000777458; SR-01000777458-2; Q15410976; (1beta)-2,2'-dimethyl-6,6',12-trimethoxyberbaman-7-ol; (1beta)-6,6',12-trimethoxy-2,2'-dimethylberbaman-7-ol
Click to Show/Hide
|
||||
| Activity |
IC50 = 129000 nM
|
[7] | |||
| Compound Name |
[5-(4-Methanesulfonyl-phenyl)-2-methyl-1-phenyl-1H-pyrrol-3-yl]-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL192678; SCHEMBL3826160; BDBM50166283; ZINC13643745; Methyl-5-[4-(methylsulfonyl)phenyl]-1-phenyl-1H-pyrrol-3-acetic Acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 132000 nM
|
[126] | |||
| Compound Name |
2-[[1-(2-Methylphenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264697; BDBM50016437
Click to Show/Hide
|
||||
| Activity |
IC50 = 132320 nM
|
[80] | |||
| Compound Name |
N-[(E)-[3-(4-Bromophenyl)-4-oxo-1,3-thiazolidin-2-ylidene]amino]-2-(2,4-dichlorophenoxy)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4100043; BDBM50235074
Click to Show/Hide
|
||||
| Activity |
IC50 = 134780 nM
|
[86] | |||
| Compound Name |
(R)-7-Tert-butyl-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1630248; SCHEMBL5171872; BDBM50332767; (2R)-7-tert-butyl-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 136000 nM
|
[70] | |||
| Compound Name |
Chembl4162061
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50279036
Click to Show/Hide
|
||||
| Activity |
IC50 = 137000 nM
|
[11] | |||
| Compound Name |
Proanthocyanidin A
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
ourateaproanthocyanidin A; CHEMBL503797; Ouratea proanthocyanidin A; ouratea-proanthocyanidin A; DTXSID10274250; BDBM50260060; ZINC42803866
Click to Show/Hide
|
||||
| Activity |
IC50 = 138000 nM
|
[7] | |||
| Compound Name |
4,6-Dimethyl-2-[1-oxo-1-(4-phenylpiperazin-1-yl)butan-2-yl]-[1,2]thiazolo[5,4-b]pyridin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3977032; BDBM50204362
Click to Show/Hide
|
||||
| Activity |
IC50 = 138038.43 nM
|
[127] | |||
| Compound Name |
5-Chloro-3-[[1-(2-fluorophenyl)triazol-4-yl]methyl]-1,3-benzoxazol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3087876; BDBM50494437
Click to Show/Hide
|
||||
| Activity |
IC50 = 138250 nM
|
[124] | |||
| Compound Name |
2-[[2-Amino-2-[1-(3-fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrol-3-yl]acetyl]amino]ethyl nitrate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3104549; BDBM50495257
Click to Show/Hide
|
||||
| Activity |
IC50 = 140000 nM
|
[128] | |||
| Compound Name |
Daphnetin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
7,8-Dihydroxycoumarin; Daphnetol; 7,8-Dihydroxy-2H-chromen-2-one; 7,8-Dihydroxy-2H-1-benzopyran-2-one; 7,8-dihydroxychromen-2-one; 2H-1-Benzopyran-2-one, 7,8-dihydroxy-; 7,8-DIHYDROXY-2H-BENZOPYRAN-2-ONE; UNII-XC84571RD2; TCMDC-125839; COUMARIN, 7,8-DIHYDROXY-; CHEMBL244948; XC84571RD2; 7,8-Dihydroxycoumarin (Daphnetin); MFCD00016977; NSC633563; 7,8-DIHYDROXY-CHROMEN-2-ONE; SMR001230713; SR-01000075820; EINECS 207-632-8; NSC 633563; BRN 0009372; 1,8-Dihydroxycoumarin; PubChem13303; 7,8-dihydroxy-coumarin; ACMC-1AKCA; SpecPlus_000864; Spectrum3_000784; Spectrum4_001254; Lopac-D-5564; Lopac0_000330; Oprea1_044324; BSPBio_002488; KBioGR_001808; 5-18-03-00211 (Beilstein Handbook Reference); MLS002153288; MLS006012039; DivK1c_006960; SCHEMBL128212; 7,8-Dihydroxycoumarin, 90%; CTK1D5894; KBio1_001904; KBio3_001708; ZINC57753; 7,8-bis(oxidanyl)chromen-2-one; DTXSID00197560; HMS3261A21; HMS3656G16; 7,8-dihydroxy-1-benzopyran-2-one; HY-N0281; Tox21_500330; ANW-43482; BBL036425; BDBM50206006; CCG-39736; CD0136; HSCI1_000053; s2554; STL558976; 7,8-Dihydroxy-2H-chromen-2-one #; AKOS000277449; LP00330; MCULE-9549774136; NSC-633563; PB17055; SDCCGSBI-0050318.P003; KS-0000122Z; 7,8-Dihydroxycoumarin, >=97%, powder; NCGC00015349-01; NCGC00015349-02; NCGC00015349-03; NCGC00015349-04; NCGC00015349-05; NCGC00015349-06; NCGC00015349-12; NCGC00093770-01; NCGC00093770-02; NCGC00261015-01; AK170408; AS-63138; SC-13560; DB-051567; CS-0008778; D4001; EU-0000106; EU-0100330; FT-0603132; N1567; ST50308908; SW000346-2; V0328; C03093; D 5564; Q-1224; 2H-1-Benzopyran-2-one, 7,8-dihydroxy- (9CI); 486D351; A827573; AE-641/02519040; Q-100543; SR-01000075820-1; SR-01000075820-2; BRD-K61269089-001-01-4; BRD-K61269089-001-02-2; Q27102315
Click to Show/Hide
|
||||
| Activity |
IC50 = 140000 nM
|
[7] | |||
| Compound Name |
2-[[1-(3,4-Dimethylphenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264700; BDBM50016419
Click to Show/Hide
|
||||
| Activity |
IC50 = 140450 nM
|
[80] | |||
| Compound Name |
2-[4-(2-Fluorophenyl)piperazin-1-ylmethyl]-4,6-dimethylisothiazolo[5,4-b]pyridin-3(2H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3912571; BDBM50204364; 2-[4-(2-Fluorophenyl)piperazin-1-ylmethyl]-4,6- dimethylisothiazolo[5,4-b]pyridin-3(2H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 141253.75 nM
|
[127] | |||
| Compound Name |
5,7-Dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288556; SCHEMBL213897; BDBM50331876
Click to Show/Hide
|
||||
| Activity |
IC50 = 145000 nM
|
[85] | |||
| Compound Name |
Chembl4172740
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50279034
Click to Show/Hide
|
||||
| Activity |
IC50 = 145000 nM
|
[11] | |||
| Compound Name |
(1R,4Ar,7S)-1,4a,7-Trimethyl-7-vinyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL345290; BDBM50097208
Click to Show/Hide
|
||||
| Activity |
IC50 = 147500 nM
|
[47] | |||
| Compound Name |
4-(4-Hydroxybenzylideneamino)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL270670; 4-[(4-Hydroxybenzylidene)amino]benzenesulfonamide; NSC720353; ARONIS016400; CTK1J4462; DTXSID00419895; ZINC249766; BDBM50229571; STK027802; AKOS000484419; MCULE-4246763113; NSC-720353; KS-0000492F; EU-0035305; ST45030750; 4-(4-hydroxy-benzylideneamino)-benzenesulfonamide; 4-[(4-Hydroxy-benzylidene)-amino]-benzenesulfonamide; 4-[(1E)-2-(4-hydroxyphenyl)-1-azavinyl]benzenesulfonamide; Benzenesulfonamide, 4-[[(4-hydroxyphenyl)methylene]amino]-; 4-{[(1E)-(4-hydroxyphenyl)methylene]amino}benzenesulfonamide; 4-{[(E)-(4-hydroxyphenyl)methylidene]amino}benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 148200 nM
|
[20] | |||
| Compound Name |
(E)-2-Methyl-5-(3-oxo-3-phenylprop-1-enyl)-6-phenylpyridazin-3(2H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL380862; BDBM50177401; 2-Methyl-5-(3-oxo-3-phenyl-1-propenyl)-6-phenyl-2,3-dihydropyridazine-3-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[129] | |||
| Compound Name |
2-(Methoxymethyl)-5-(3-oxo-3-phenyl-1-propenyl)-6-phenylpyridazine-3(2H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL205174; SCHEMBL1752765; BDBM50177392; ZINC28569538; (E)-2-(methoxymethyl)-5-(3-oxo-3-phenylprop-1-enyl)-6-phenylpyridazin-3(2H)-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[129] | |||
| Compound Name |
4-Methyl-N''-((4-oxo-4H-chromen-3-yl)methylene)benzenesulfonohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1241823; BDBM50326127
Click to Show/Hide
|
||||
| Activity |
IC50 = 150450 nM
|
[130] | |||
| Compound Name |
Chembl4165597
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50279035
Click to Show/Hide
|
||||
| Activity |
IC50 = 152000 nM
|
[11] | |||
| Compound Name |
2-(4-Methylphenyl)sulfonyl-3-naphthalen-1-yl-5-(trifluoromethyl)-3,4-dihydropyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3309827; BDBM50045704
Click to Show/Hide
|
||||
| Activity |
IC50 = 152600 nM
|
[57] | |||
| Compound Name |
2-[[1-(4-Tert-butylphenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264701; BDBM50016427
Click to Show/Hide
|
||||
| Activity |
IC50 = 154260 nM
|
[80] | |||
| Compound Name |
4-[(4-Hydroxy-3,5-dimethoxyphenyl)methylideneamino]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL270087; BDBM50371751
Click to Show/Hide
|
||||
| Activity |
IC50 = 155950 nM
|
[20] | |||
| Compound Name |
3-Phenyl-4-(4-azidophenyl)furan-2(5H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL102223; BDBM50103510; 4-(4-Azido-phenyl)-3-phenyl-5H-furan-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 159720 nM
|
[106] | |||
| Compound Name |
(NZ)-N-[[1-(3,4-difluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrol-3-yl]methylidene]hydroxylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391052; BDBM50492039
Click to Show/Hide
|
||||
| Activity |
IC50 = 161000 nM
|
[40] | |||
| Compound Name |
2-[[1-(4-Ethoxyphenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264702; BDBM50016428
Click to Show/Hide
|
||||
| Activity |
IC50 = 163240 nM
|
[80] | |||
| Compound Name |
Chembl4176892
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50279023
Click to Show/Hide
|
||||
| Activity |
IC50 = 167000 nM
|
[11] | |||
| Compound Name |
4-[(3,4,5-Trimethoxybenzylidene)amino]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL404607; NSC720514; CTK6J4938; ZINC1090361; BDBM50371752; AKOS024364693; MCULE-7698299587; NSC-720514; ST50997032; SR-01000199560; SR-01000199560-1; 4-[(3,5-Trimethoxy-benzylidene)-amino]-benzenesulfonamide; 4-[(1E)-2-(3,4,5-trimethoxyphenyl)-1-azavinyl]benzenesulfonamide; 4-{[(e)-(3,4,5-trimethoxyphenyl)methylidene]amino}benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 167090 nM
|
[20] | |||
| Compound Name |
6,8-Dimethyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288600; SCHEMBL5169751; BDBM50331060; (2S)-6,8-Dimethyl-2-(trifluoromethyl)-2H-1-benzopyran-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 169000 nM
|
[68] | |||
| Compound Name |
4,6-Dimethyl-2-[3-oxo-3-(4-phenylpiperazin-1-yl)propyl]-[1,2]thiazolo[5,4-b]pyridin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3903347; BDBM50204422
Click to Show/Hide
|
||||
| Activity |
IC50 = 169824.37 nM
|
[127] | |||
| Compound Name |
2-[(4,6-Dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl)oxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3933250; BDBM50204421
Click to Show/Hide
|
||||
| Activity |
IC50 = 169824.37 nM
|
[127] | |||
| Compound Name |
2-[[2-Anilinoethyl(methyl)amino]methyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3974473; BDBM50204360
Click to Show/Hide
|
||||
| Activity |
IC50 = 173780.08 nM
|
[127] | |||
| Compound Name |
Sodium;2-[3-(4-fluorophenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814716
Click to Show/Hide
|
||||
| Activity |
IC50 = 174000 nM
|
[52] | |||
| Compound Name |
Sodium;2-[2-(4-fluorophenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814724
Click to Show/Hide
|
||||
| Activity |
IC50 = 174000 nM
|
[52] | |||
| Compound Name |
3-[[1-(4-Fluorophenyl)triazol-4-yl]methyl]-6-methyl-1,3-benzoxazol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3087872; BDBM50494435
Click to Show/Hide
|
||||
| Activity |
IC50 = 174720 nM
|
[124] | |||
| Compound Name |
Chembl4169030
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50279038
Click to Show/Hide
|
||||
| Activity |
IC50 = 178000 nM
|
[11] | |||
| Compound Name |
8-Fluoro-2-[3-[3-fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-5-[(4-methylsulfonylphenyl)methyl]-3,4-dihydro-1H-pyrido[4,3-b]indole;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1164943
Click to Show/Hide
|
||||
| Activity |
IC50 = 180300 nM
|
[131] | |||
| Compound Name |
4-[(4,6-Dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl)oxy]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3924311; BDBM50204366
Click to Show/Hide
|
||||
| Activity |
IC50 = 181970.09 nM
|
[127] | |||
| Compound Name |
2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]-3-oxopropyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3974298; BDBM50204363
Click to Show/Hide
|
||||
| Activity |
IC50 = 181970.09 nM
|
[127] | |||
| Compound Name |
4-[(4-Trifluoromethyl-benzylidene)-amino]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL270246; NSC720520; CTK7B6627; BDBM50371764; NSC-720520; 4-({(e)-[4-(trifluoromethyl)phenyl]methylidene}amino)benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 182190 nM
|
[20] | |||
| Compound Name |
4-[(4-Sulfamoyl-phenylimino)-methyl]-benzoic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL406434; NSC720587; CTK6I9834; BDBM50371767; NSC-720587; NCI60_041315; methyl 4-{(e)-[(4-sulfamoylphenyl)imino]methyl}benzoate
Click to Show/Hide
|
||||
| Activity |
IC50 = 183500 nM
|
[20] | |||
| Compound Name |
2-[[1-(4-Bromophenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264695; BDBM50016435
Click to Show/Hide
|
||||
| Activity |
IC50 = 186110 nM
|
[80] | |||
| Compound Name |
3-[[1-(4-Bromophenyl)triazol-4-yl]methyl]-5-methyl-1,3-benzoxazol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3087873; BDBM50494439
Click to Show/Hide
|
||||
| Activity |
IC50 = 188200 nM
|
[124] | |||
| Compound Name |
2-[[1-(4-Fluorophenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264696; BDBM50016436
Click to Show/Hide
|
||||
| Activity |
IC50 = 192150 nM
|
[80] | |||
| Compound Name |
4-(4,6-Dimethyl-3-oxo-[1,2]thiazolo[5,4-b]pyridin-2-yl)butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3905241; BDBM50204417
Click to Show/Hide
|
||||
| Activity |
IC50 = 194984.46 nM
|
[127] | |||
| Compound Name |
4-((4-(Dimethylamino)benzylidene)amino)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
NSC209929; CHEMBL270671; (E)-4-((4-(dimethylamino)benzylidene)amino)benzenesulfonamide; 4-{(1E)-2-[4-(dimethylamino)phenyl]-1-azavinyl}benzenesulfonamide; 4-[[4-(Dimethylamino)benzylidene]amino]benzenesulfonamide; 4-{[4-(Dimethylamino)benzylidene]amino}benzenesulfonamide; NSC 209929; CBDivE_016049; SCHEMBL1517567; SCHEMBL12416681; CTK5H3838; BDBM50371765; CCG-52936; STK871822; ZINC17952865; AKOS001268815; ZINC102808390; MCULE-4671899700; NSC-209929; ST016436; DS-014426; SR-01000642134-1; 4-(4-(Dimethylamino)Benzylideneamino)Benzenesulfonamide; F0777-0184; 4[(4-dimethylamino-benzylidene)-amino]-benzene sulphonamide; 4-[(E)-(4-dimethylaminophenyl)methyleneamino]benzenesulfonamide; 4-{[4-(dimethylamino)benzylidene]amino}benzene-1-sulfonamide; 4-({(E)-[4-(dimethylamino)phenyl]methylidene}amino)benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 195740 nM
|
[20] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 79 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
FENOFIBRIC ACID
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
Fenofibric acid; 42017-89-0; Procetofenic acid; 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid; alpha 1081; NSC 281318; LF 178 acid; UNII-BGF9MN2HU1; 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid; LF 153; FNF Acid; C17H15ClO4; Trilipix; CCRIS 7302; EINECS 255-626-9; BGF9MN2HU1; CHEMBL981; BRN 2058973; CHEBI:83469; 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic Acid; Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-; AK117112; 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoic acid; W-106287
Click to Show/Hide
|
||||
| Activity |
IC50 = 950000 nM
|
[6] | |||
| Compound Name |
3,4-Dihydroxycinnamic Acid
Click to Show/Hide
|
Phase 4 | Compound Info | ||
| Synonyms |
Caffeic acid; caffeic acid; 3,4-Dihydroxycinnamic acid; 331-39-5; 3-(3,4-dihydroxyphenyl)acrylic acid; 501-16-6; (E)-3-(3,4-dihydroxyphenyl)acrylic acid; 3,4-Dihydroxybenzeneacrylic acid; (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid; trans-caffeic acid; trans-Caffeate; 3,4-Dihydroxy-trans-cinnamate; 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-; Cinnamic acid, 3,4-dihydroxy-; 3-(3,4-Dihydroxyphenyl)propenoic acid; UNII-U2S3A33KVM; 3-(3,4-Dihydroxyphenyl)-2-propenoic acid; 4-(2-Carboxyethenyl)-1,2-dihydroxybenzene
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[132] | |||
| Compound Name |
URSOLIC ACID
Click to Show/Hide
|
Phase 2 | Compound Info | ||
| Synonyms |
Ursolic acid; Prunol; Malol; Urson; 77-52-1; 3beta-Hydroxyurs-12-en-28-oic acid; (3beta)-3-Hydroxyurs-12-en-28-oic acid; 3beta-Hydroxy-12-ursen-28-ic acid; UNII-P3M2575F3F; CHEBI:9908; CCRIS 7123; EINECS 201-034-0; CHEMBL169; Merotaine; AI3-03109; NSC4060; P3M2575F3F; NSC-4060; Urs-12-en-28-oic acid, 3-hydroxy-, (3beta)-; HNMR; .beta.-Ursolic acid; NSC 4060; NSC 167406
Click to Show/Hide
|
||||
| Activity |
IC50 = 210000 nM
|
[133] | |||
| Compound Name |
4-(4-methoxy-benzylideneamino)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL271911; N-(4-Methoxybenzylidene)-4-sulfamoylaniline; 66667-56-9; AC1LCE5G; CBDivE_014997; SCHEMBL1517619; 4-[(4-methoxyphenyl)methylideneamino]benzenesulfonamide; CTK1J4463; DTXSID70347792; MolPort-000-519-122; MLUHDVSELBSKPI-UHFFFAOYSA-N; MLUHDVSELBSKPI-MHWRWJLKSA-N; ZINC131008; BDBM50371762; STK790787; AKOS001583663; MCULE-9167737347; MCULE-3795342438; ST016434; 4-(4-Methoxybenzylideneamino)benzenesulfonamide; Benzenesulfonamide, 4-(4-methoxybenzylideneamino)-; 4-((4-METHOXYBENZYLIDENE)AMINO)BENZENESULFONAMIDE
Click to Show/Hide
|
||||
| Activity |
IC50 = 313830 nM
|
[20] | |||
| Compound Name |
OLEANOLIC_ACID
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
OLEANOLIC ACID; Oleanic acid; 508-02-1; Caryophyllin; Astrantiagenin C; Giganteumgenin C; Virgaureagenin B; 3beta-Hydroxyolean-12-en-28-oic acid; UNII-6SMK8R7TGJ; CCRIS 6493; (3-beta)-3-Hydroxyolean-12-en-28-oic acid; EINECS 208-081-6; NSC114945; 6SMK8R7TGJ; NSC-114945; 3-beta-Hydroxyolean-12-en-28-oic acid; CHEBI:37659; Olean-12-en-28-oic acid, 3-hydroxy-, (3beta)-; oleonolic acid; MFCD00064914
Click to Show/Hide
|
||||
| Activity |
IC50 = 380000 nM
|
[7] | |||
| Compound Name |
4-(3-methoxy-benzylideneamino)-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL271930; NSC720589; AC1L8N6O; CTK7A8689; BDBM50371745; NSC-720589; 4-[(3-Methoxy-benzylidene)-amino]-benzenesulfonamide; 4-[(3-methoxyphenyl)methylideneamino]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 383360 nM
|
[20] | |||
| Compound Name |
SEROTONIN
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
serotonin; 5-HYDROXYTRYPTAMINE; 3-(2-Aminoethyl)-1H-indol-5-ol; 50-67-9; Enteramine; 5-HT; Serotonine; Thrombotonin; Thrombocytin; Antemovis; Ds substance; Hippophain; Antemoqua; Substance DS; Substanz DS; 1H-Indol-5-ol, 3-(2-aminoethyl)-; 5-Hta; Tryptamine, 5-hydroxy-; 3-(2-Aminoethyl)indol-5-ol; Enteramin; UNII-333DO1RDJY; Indol-5-ol, 3-(2-aminoethyl)-; 5-Hydroxy-3-(beta-aminoethyl)indole; 3-(beta-Aminoethyl)-5-hydroxyindole; EINECS 200-058-9; 3-(2-Amino-ethyl)-1H-indol-5-ol; BRN 0143524; 333DO1RDJY; CHEBI:28790
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[132] | |||
| Compound Name |
Atractylon
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Atractylone; CHEMBL486189; Atractylol; Atractyloxide; SCHEMBL19082783; DTXSID50220170; HY-N2095; BDBM50241938; MFCD00210477; s9158; ZINC33833583; AKOS016013441; CCG-266696; CS-0018600; C16919; Q27149840
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[69] | |||
| Compound Name |
Atractylenolide II
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-Atractylenolide; Asterolide; CHEMBL485805; Q63398440; 8,12-EPOXYEUDESMA-4(14),7(11)-DIEN-12-ONE; ATRACTYLENOLIDE 2; SCHEMBL19082785; HMS3886J22; HY-N0202; BDBM50241946; MFCD09037396; ZINC15207329; AKOS025119314; CCG-266807; CS-3670; N2205; S9314; X1091; C17886; 069A144; Q-100801
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[69] | |||
| Compound Name |
Atractylenolide I
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Atractylenolide-1; Atractylenolide 1; CHEMBL449520; Q63396593; 8,12-EPOXYEUDESMA-4(14),7(11),8-TRIEN-12-ONE; 8,9-dehydroasterolide; Atractylenolide-I; SCHEMBL1898423; HMS3886N08; HY-N0201; BDBM50241939; MFCD09037395; s8291; ZINC15207341; Atractylenolide I, >=98% (HPLC); AKOS025119313; CCG-266793; CCG-266794; CS-3669; N2541; X1093; C17885; 069A133; Q-100800
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[69] | |||
| Compound Name |
Atractylenolide III
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Codonolactone; 8beta-Hydroxyasterolide; 8-Hydroxyasterolide; CHEMBL486961; AtractylenolideIII; MFCD00238543; 8,12-EPOXYEUDESMA-4(14),7(11)-DIEN-8-OL-12-ONE; Atractylenolide-III; HSDB 8108; Atractylenolide beta; Atractylodes japonica; ATRACTYLENOLIDE 3; SCHEMBL19082784; DTXSID50223308; BCP18761; HY-N0203; ZINC5373275; BDBM50241945; s9313; AKOS015897171; Atractylenolide III, >=98% (HPLC); CCG-266941; CS-3671; MCULE-9995877189; NCGC00385304-01; N2540; X1092; C17887; 030A714; Q-100798; Q27138303
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[69] | |||
| Compound Name |
5-Ethyl-1,2,4-tris(4-hydroxyphenyl)-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL195142; BDBM50174672; 4-[5-ethyl-1,2-bis(4-hydroxyphenyl)-1H-imidazol-4-yl]phenol
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[134] | |||
| Compound Name |
Osthole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Osthol; Ostol; Ostole; 7-Methoxy-8-isopentenylcoumarin; 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one; NSC 31868; 8-(3-Methyl-2-butenyl)herniarin; 7-METHOXY-8-(3-METHYL-2-BUTENYL)-COUMARIN; 7-methoxy-8-(3-methyl-2-butenyl)coumarin; UNII-XH1TI1759C; Coumarin, 7-methoxy-8-(3-methyl-2-butenyl)-; CHEMBL52229; XH1TI1759C; NSC31868; 7-Methoxy-8-(3-methyl-but-2-enyl)-chromen-2-one; MFCD00076049; 7-methoxy-8-(3-methylbut-2-enyl)-2H-chromen-2-one; SMR000156202; Osthole (Osthol); Osthole,(S); Cnidium Fruit Extract; Spectrum_001542; SpecPlus_000946; Spectrum2_000723; Spectrum3_001645; Spectrum4_001687; Spectrum5_000334; Osthole, analytical standard; Oprea1_642606; Oprea1_873803; SCHEMBL50436; BSPBio_003369; KBioGR_001954; KBioSS_002022; ZINC566; MLS000574904; MLS001048988; MLS006011425; DivK1c_007042; SPECTRUM1504165; SPBio_000646; MEGxp0_000155; ACon1_002155; CTK7A8592; GTPL10302; HSDB 8479; KBio1_001986; KBio2_002022; KBio2_004590; KBio2_007158; KBio3_002589; DTXSID20197507; HMS2267O21; HMS3656A07; BCP10832; EBD33224; HY-N0054; KS-00000N3A; ANW-50075; BBL013019; BDBM50240512; CCG-40172; CO0040; NSC-31868; s2337; STK396321; AKOS000277663; AC-8041; DS-0881; MCULE-5691054147; SDCCGMLS-0066780.P001; NCGC00095694-01; NCGC00095694-02; NCGC00095694-03; NCGC00095694-05; WLN: T66 BOVJ IO1 J2UY1&1; AK-35300; BR-35300; AB0021820; FT-0601535; N1825; O0426; ST50909221; SW219438-1; W1256; C09280; J10077; S-3211; 484O128; A827530; SR-01000721624; Q-100535; Q4338679; SR-01000721624-4; BRD-K78294846-001-03-3
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[69] | |||
| Compound Name |
Chembl4161755
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50279040
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|
||||
| Activity |
IC50 = 201000 nM
|
[11] | |||
| Compound Name |
3-(4-Chlorophenoxy)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL420351; SCHEMBL1376506; BDBM50150194; ZINC00588142; 3-(4-Chloro-phenoxy)-2-(4-methanesulfonyl-phenyl)-6-methyl-pyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 207000 nM
|
[4] | |||
| Compound Name |
3-[[1-(2-Chlorophenyl)triazol-4-yl]methyl]-6-methyl-1,3-benzoxazol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3087874; BDBM50494440
Click to Show/Hide
|
||||
| Activity |
IC50 = 207360 nM
|
[124] | |||
| Compound Name |
4-[5-Pyridin-4-yl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL283425; SCHEMBL6341797; BDBM50057529; 4-(5-Pyridin-4-yl-3-trifluoromethyl-pyrazol-1-yl)-benzenesulfonamide
Click to Show/Hide
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||||
| Activity |
IC50 = 209000 nM
|
[45] | |||
| Compound Name |
4-(Dimethylamino)-2-methyl-5-(3-oxo-3-phenylprop-1-enyl)pyridazin-3(2H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL202451; BDBM50177395
Click to Show/Hide
|
||||
| Activity |
IC50 = 221300 nM
|
[129] | |||
| Compound Name |
6-Methyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288468; SCHEMBL6091737; BDBM50331050
Click to Show/Hide
|
||||
| Activity |
IC50 = 224000 nM
|
[68] | |||
| Compound Name |
(1R,4Ar,7S)-7-Ethyl-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL435432; BDBM50097205
Click to Show/Hide
|
||||
| Activity |
IC50 = 229000 nM
|
[47] | |||
| Compound Name |
2-[2-[4-(3-Chlorophenyl)piperazin-1-yl]-2-oxoethyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3906347; BDBM50204327
Click to Show/Hide
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||||
| Activity |
IC50 = 229086.77 nM
|
[127] | |||
| Compound Name |
3-Methoxyacetaminophen
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3-Methoxy Acetaminophen; N-(4-hydroxy-3-methoxyphenyl)acetamide; UNII-0GPW365VZ9; Acetamide,N-(4-hydroxy-3-methoxyphenyl)-; 0GPW365VZ9; CHEMBL498882; Acetamide, N-(4-hydroxy-3-methoxyphenyl)-; 3-methoxyparacetamol; 4-acetamido-2-methoxyphenol; SCHEMBL258201; CTK4G8828; DTXSID40186236; BDBM50246685; ZINC22062048; AKOS006275401; N-(3-Methoxy-4-hydroxyphenyl)acetamide; FT-0671061; J-018775; Q27236761
Click to Show/Hide
|
||||
| Activity |
IC50 = 234000 nM
|
[135] | |||
| Compound Name |
2-[[1-(4-Ethylphenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264690; BDBM50016442
Click to Show/Hide
|
||||
| Activity |
IC50 = 246200 nM
|
[80] | |||
| Compound Name |
3-(2-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL421381; BDBM50118682; 3-(2-Hydroxyphenyl)-4-[4-(methylsulfonyl)phenyl]-2,5-dihydrofuran-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 250000 nM
|
[114] | |||
| Compound Name |
3-(3-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL91923; BDBM50118685; 3-(3-Hydroxyphenyl)-4-[4-(methylsulfonyl)phenyl]-2,5-dihydrofuran-2-one
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[114] | |||
| Compound Name |
4-(1-(4-(Aminosulfonyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)benzoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
Celecoxib Carboxylic Acid; Carboxylic acid celecoxib; carboxycelecoxib; UNII-EQJ1364UKF; CHEMBL743; 4-[2-(4-sulfamoylphenyl)-5-(trifluoromethyl)pyrazol-3-yl]benzoic Acid; EQJ1364UKF; CARBOXYLIC ACID METABOLITE OF CELECOXIB; 4-[1-[4-(Aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoic Acid; SC-62807; Celecoxib metabolite M2; 4-[1-(4-(Aminosulfonyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl]benzoic acid; SCHEMBL6342903; CTK4D3618; DTXSID40434744; BCP33283; BDBM50057540; ZINC13761819; AKOS030255951; AS-6154; FT-0664445; J-010632; Q27277309; 4-[2-(4-Sulfamoyl-phenyl)-5-trifluoromethyl-2H-pyrazol-3-yl]-benzoic acid
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[45] | |||
| Compound Name |
3-(4-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-5H-furan-2-one
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL313527; 4'-Hydroxyrofecoxib; SCHEMBL17378057; BDBM50094985
Click to Show/Hide
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||||
| Activity |
IC50 > 250000 nM
|
[114] | |||
| Compound Name |
2,3-Dimethyl-4-phenyl-5-[4-(methylsulfonyl)phenyl]-4-isoxazoline
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL444805; BDBM50103310; 5-(4-Methanesulfonyl-phenyl)-2,3-dimethyl-4-phenyl-2,3-dihydro-isoxazole
Click to Show/Hide
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||||
| Activity |
IC50 = 258110 nM
|
[116] | |||
| Compound Name |
4,6-Dimethyl-2-[4-oxo-4-(4-phenylpiperazin-1-yl)butyl]-[1,2]thiazolo[5,4-b]pyridin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3948850; BDBM50204368
Click to Show/Hide
|
||||
| Activity |
IC50 = 263026.8 nM
|
[127] | |||
| Compound Name |
4-[4,5-Difluoro-2-(6-methylpyridin-3-yl)phenyl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL292413; SCHEMBL6724063; BDBM50049663; 4'',5''-Difluoro-2''-(6-methyl-pyridin-3-yl)-biphenyl-4-sulfonic acid amide
Click to Show/Hide
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||||
| Activity |
IC50 = 265000 nM
|
[88] | |||
| Compound Name |
(1R,4Ar,7S)-7-(2-Acetoxy-ethyl)-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL357965; BDBM50097202
Click to Show/Hide
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||||
| Activity |
IC50 = 265700 nM
|
[47] | |||
| Compound Name |
Sodium;2-[2-iodo-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814708
Click to Show/Hide
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||||
| Activity |
IC50 = 270000 nM
|
[52] | |||
| Compound Name |
3-(3,5-Dihydroxyphenyl)-6,8-dihydroxy-2H-1-benzopyran-2-one
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL199739; CTK3C4456; DTXSID00658767; BDBM50176527; 6,8-dihydroxy-3-(3'',5''-dihydroxyphenyl)coumarin; 2H-1-Benzopyran-2-one, 3-(3,5-dihydroxyphenyl)-6,8-dihydroxy-
Click to Show/Hide
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||||
| Activity |
IC50 = 285000 nM
|
[67] | |||
| Compound Name |
1-[4-(Methylsulfonyl)phenyl]-2-(3-chloro-4-methoxyphenyl)-4-(trifluoromethyl)-1H-imidazole
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL43149; SCHEMBL3249658; BDBM50057999; 2-(3-Chloro-4-methoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole; 2-(3-chloro-4-methoxyphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole; 2-(3-chloro-4-methoxyphenyl)-1-[4-(methylsulfonyl)phenyl]-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
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||||
| Activity |
IC50 = 296000 nM
|
[49] | |||
| Compound Name |
3-(3,4-Difluoro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL280009; SCHEMBL7836931; BDBM50125627; 3-(3,4-difluorophenyl)-5-hydroxy-5-methyl-4-(4-methylsulfonylphenyl)furan-2-one; 3-(3,4-Difluorophenyl)-4-[4-(methylsulfonyl)phenyl]-5-hydroxy-5-methyl-2,5-dihydrofuran-2-one
Click to Show/Hide
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||||
| Activity |
IC50 > 300000 nM
|
[56] | |||
| Compound Name |
7,8-Dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288591; SCHEMBL6093876; BDBM50331878
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[85] | |||
| Compound Name |
2-Amino-2-[1-(3-fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrol-3-yl]-N-(2-hydroxyethyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3104551; BDBM50495260
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[128] | |||
| Compound Name |
2-[3-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-oxopropyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3915322; BDBM50204361
Click to Show/Hide
|
||||
| Activity |
IC50 = 301995.17 nM
|
[127] | |||
| Compound Name |
2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]-3-oxopropyl]-1,2-benzothiazol-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3958352; BDBM50204369
Click to Show/Hide
|
||||
| Activity |
IC50 = 301995.17 nM
|
[127] | |||
| Compound Name |
4-[2-(5-Methylpyridin-2-yl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL327078; SCHEMBL5594798; BDBM50091203; 4-[2-(5-Methyl-2-pyridinyl)-4-(trifluoromethyl)-1H-imidazole-1-yl]benzenesulfonamide; 4-[2-(5-Methyl-pyridin-2-yl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 302000 nM
|
[53] | |||
| Compound Name |
Sodium;2-[4-[(2-oxocyclopentyl)methyl]-2-phenylphenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814720
Click to Show/Hide
|
||||
| Activity |
IC50 = 310000 nM
|
[52] | |||
| Compound Name |
Sodium;2-[2-(4-hydroxyphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814726
Click to Show/Hide
|
||||
| Activity |
IC50 = 326000 nM
|
[52] | |||
| Compound Name |
4-[2-(3-Methyl-pyridin-2-yl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL321016; SCHEMBL5604428; BDBM50091187; 4-[2-(3-Methyl-2-pyridinyl)-4-(trifluoromethyl)-1H-imidazole-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 338000 nM
|
[53] | |||
| Compound Name |
2-(3-Chlorophenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42175; SCHEMBL212953; BDBM50057984; 1-[4-(Methylsulfonyl)phenyl]-2-(3-chlorophenyl)-4-(trifluoromethyl)-1H-imidazole; 2-(3-Chloro-phenyl)-1-(4-methanesulfonyl-phenyl)-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 360000 nM
|
[49] | |||
| Compound Name |
2-[4-[4-(3-Chlorophenyl)piperazin-1-yl]-4-oxobutyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3930586; BDBM50204418
Click to Show/Hide
|
||||
| Activity |
IC50 = 371535.23 nM
|
[127] | |||
| Compound Name |
1-[4-(3-Chlorophenyl)piperazin-1-yl]-4-[(4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl)oxy]butan-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3978014; BDBM50204365
Click to Show/Hide
|
||||
| Activity |
IC50 = 380189.4 nM
|
[127] | |||
| Compound Name |
2-(5-Methoxy-1H-benzimidazole-2-ylthiomethyl)-3-pentadecylphenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL347705; BDBM50124787; 2-(5-Methoxy-1H-benzoimidazol-2-ylsulfanylmethyl)-3-pentadecyl-phenol
Click to Show/Hide
|
||||
| Activity |
IC50 = 384000 nM
|
[136] | |||
| Compound Name |
3-[[1-(4-Chlorophenyl)triazol-4-yl]methyl]-6-methyl-1,3-benzoxazol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3087871; BDBM50494438
Click to Show/Hide
|
||||
| Activity |
IC50 = 389200 nM
|
[124] | |||
| Compound Name |
N-Caffeoyl serotonin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
UNII-574297D1EQ; CHEMBL559089; 574297D1EQ; Cafeoylserotonin 98; caffeoylserotonin; caffeic acid serotonin amide; SCHEMBL803616; DTXSID70239168; BDBM50296247; Q27261461; N-[(E)-3,4-Dihydroxycinnamoyl]-5-hydroxy-1H-indole-3-ethaneamine; 3-(3,4-Dihydroxyphenyl)-N-[2-(5-hydroxyindol-3-yl)ethyl]-2-propenamide; 3-[2-[[3-(3,4-Dihydroxyphenyl)propenoyl]amino]ethyl]-1H-indole-5-ol; (E)-3-(3,4-dihydroxyphenyl)-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]prop-2-enamide
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[132] | |||
| Compound Name |
2-[1-(4-Chlorobenzoyl)-2-phenylindol-3-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946749; BDBM50362894
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[137] | |||
| Compound Name |
2-[1-(4-Chlorobenzoyl)-2-ethylindol-3-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946565; BDBM50362893
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[137] | |||
| Compound Name |
N-Sinapoyl Serotonin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1760551; SCHEMBL803240; BDBM50341139
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[132] | |||
| Compound Name |
N'-[(E)-(4-Oxo-4H-chromen-3-yl)methylidene]benzenecarbohydrazide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1241822; N'-[(1E)-(4-oxo-4H-chromen-3-yl)methylidene]benzohydrazide; MLS000763907; SCHEMBL3342977; BDBM50326128; AKOS005094610; SMR000336524; 5W-0284; N''-((4-oxo-4H-chromen-3-yl)methylene)benzohydrazide
Click to Show/Hide
|
||||
| Activity |
IC50 = 405960 nM
|
[130] | |||
| Compound Name |
Sodium;2-[4-[(2-oxocyclopentyl)methyl]-3-[4-(trifluoromethoxy)phenyl]phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814717
Click to Show/Hide
|
||||
| Activity |
IC50 = 460000 nM
|
[52] | |||
| Compound Name |
Sodium;2-[2-(4-methylphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814721
Click to Show/Hide
|
||||
| Activity |
IC50 = 470000 nM
|
[52] | |||
| Compound Name |
N-[4-[2-(3,4-Dichlorophenyl)ethyl]phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1086610; BDBM50313196
Click to Show/Hide
|
||||
| Activity |
IC50 = 489000 nM
|
[35] | |||
| Compound Name |
2-Methoxy-6-pentadecylbenzyl 2-benzoxazolyl sulfide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL161619; BDBM50124782; 2-(2-Methoxy-6-pentadecyl-benzylsulfanyl)-benzooxazole
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[138] | |||
| Compound Name |
6-Formyl-2-trifluoromethyl-2H-chromene-3-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1288469; 6-formyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid; SCHEMBL5708972; BDBM50331051; 6-formyl-2-(trifluoromethyl)-2H-1-benzopyran-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 500000 nM
|
[68] | |||
| Compound Name |
2-Ethoxy-6-pentadecylbenzyl 5-nitro-1H-benzimidazole-2-yl sulfide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL158842; BDBM50124785; 2-(2-Ethoxy-6-pentadecyl-benzylsulfanyl)-5-nitro-1H-benzoimidazole
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[138] | |||
| Compound Name |
2-Ethoxy-6-pentadecylbenzyl 1H-benzimidazole-2-yl sulfide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL158421; BDBM50124790; 2-(2-Ethoxy-6-pentadecyl-benzylsulfanyl)-1H-benzoimidazole
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[138] | |||
| Compound Name |
2-Ethoxy-6-pentadecylbenzyl 5-methoxy-1H-benzimidazole-2-yl sulfide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL353353; BDBM50124786; 2-(2-Ethoxy-6-pentadecyl-benzylsulfanyl)-5-methoxy-1H-benzoimidazole
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[138] | |||
| Compound Name |
2-(4-Methylphenyl)sulfonyl-3-naphthalen-2-yl-5-(trifluoromethyl)-3,4-dihydropyrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3309828; BDBM50045703
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[57] | |||
| Compound Name |
2-(2-Methoxy-6-pentadecyl-benzylsulfanyl)-5-nitro-1H-benzoimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL159206; BDBM50124793; 2-Methoxy-6-pentadecylbenzyl 5-nitro-1H-benzimidazole-2-yl sulfide
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[138] | |||
| Compound Name |
2-Methoxy-6-pentadecylbenzyl 5-methyl-1H-benzimidazole-2-yl sulfide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL161788; BDBM50124788; 2-(2-Methoxy-6-pentadecyl-benzylsulfanyl)-5-methyl-1H-benzoimidazole
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[138] | |||
| Compound Name |
2-Methoxy-6-pentadecylbenzyl 2-benzothiazolyl sulfide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL158495; BDBM50124792; 2-(2-Methoxy-6-pentadecyl-benzylsulfanyl)-benzothiazole
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[138] | |||
| Compound Name |
Sodium;2-[4-[(2-oxocyclopentyl)methyl]-2-[4-(trifluoromethoxy)phenyl]phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814706
Click to Show/Hide
|
||||
| Activity |
IC50 = 515000 nM
|
[52] | |||
| Compound Name |
Fraxetin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
7,8-Dihydroxy-6-methoxycoumarin; 7,8-Dihydroxy-6-methoxy-2H-chromen-2-one; 7,8-dihydroxy-6-methoxychromen-2-one; 2H-1-Benzopyran-2-one, 7,8-dihydroxy-6-methoxy-; UNII-CD3GD44O3K; 7,8-Dihydroxy-6-methoxy-2-benzopyrone; CD3GD44O3K; 7,8-Dihydroxy-6-methoxy-chromen-2-one; CHEMBL54909; Fraxetol; 8-hydroxyscopoletin; EINECS 209-376-2; Spectrum_001507; SpecPlus_000477; Spectrum2_001639; Spectrum3_001842; Spectrum4_001686; Spectrum5_000332; Oprea1_735469; SCHEMBL43472; BSPBio_003224; Fraxetin, analytical standard; KBioGR_001952; KBioSS_001987; MLS002207123; DivK1c_006573; SPECTRUM1504069; SPBio_001737; MEGxp0_000506; ACon0_001071; ACon1_000442; CTK8E5461; KBio1_001517; KBio2_001987; KBio2_004555; KBio2_007123; KBio3_002724; DTXSID00205992; KUC106681N; ZINC113309; HY-N0580; TNP00177; Coumarin, 7,8-dihydroxy-6-methoxy; BDBM50206215; CCG-38759; MFCD00006873; s9503; STL564671; Coumarin, 7,8-dihydroxy-6-methoxy-; AKOS000277991; MCULE-2693568829; 7,8-Dihydroxy-6-methoxycoumarin, 98%; NCGC00017270-01; NCGC00017270-02; NCGC00017270-03; NCGC00017270-04; NCGC00017270-05; NCGC00096046-01; NCGC00096046-02; NCGC00169075-01; NCGC00169075-02; AK114503; AS-67313; SC-65962; SMR000112323; ST024715; KSC-11-207-12; DB-050316; CS-0009115; FT-0632418; N1765; V1540; 7,8-Dihydroxy-6-methoxy-2H-chromen-2-one #; A14554; C09265; 574F845; SR-05000002449; Q-100662; SR-05000002449-1; BRD-K76587808-001-03-8; Q15410973
Click to Show/Hide
|
||||
| Activity |
IC50 = 524000 nM
|
[7] | |||
| Compound Name |
2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl]-4,6-dimethyl-isothiazolo[5,4-b]pyridin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2419964; Isothiazolo[5,4-b]pyridin-3(2H)-one, 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-4,6-dimethyl-; BDBM50204423
Click to Show/Hide
|
||||
| Activity |
IC50 = 524807.46 nM
|
[127] | |||
| Compound Name |
Thiazolidin-5-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,3-thiazolidin-5-one; CHEMBL338595; SCHEMBL1257983; BDBM50369461; AKOS006378852
Click to Show/Hide
|
||||
| Activity |
IC50 = 540000 nM
|
[139] | |||
| Compound Name |
Sodium;2-[2-(4-methylsulfanylphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814723
Click to Show/Hide
|
||||
| Activity |
IC50 = 575000 nM
|
[52] | |||
| Compound Name |
1-(4-Methanesulfonyl-phenyl)-2-o-tolyl-4-trifluoromethyl-1H-imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44466; SCHEMBL5594456; BDBM50057921; 2-(2-methylphenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole; 1-[4-(Methylsulfonyl)phenyl]-2-(2-methylphenyl)-4-(trifluoromethyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 577000 nM
|
[49] | |||
| Compound Name |
Sodium;2-[4-[[(1R,2S)-2-hydroxycyclopentyl]methyl]-2-(4-hydroxyphenyl)phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814727
Click to Show/Hide
|
||||
| Activity |
IC50 = 650000 nM
|
[52] | |||
| Compound Name |
2-[(4-Cyclohexylpiperazin-1-yl)methyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3965233; BDBM50204420
Click to Show/Hide
|
||||
| Activity |
IC50 = 660693.45 nM
|
[127] | |||
| Compound Name |
4-[5-(7-Methyl-benzo[1,3]dioxol-5-yl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL29403; SCHEMBL6343974; BDBM50057582; 4-[5-(7-methyl-1,3-benzodioxol-5-yl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 674000 nM
|
[45] | |||
| Compound Name |
Methyl 2-acetoxy-3-(5-methoxy-5-oxopentyl)benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL540236; BDBM50297766
Click to Show/Hide
|
||||
| Activity |
IC50 = 720000 nM
|
[140] | |||
| Compound Name |
1-(4-Methylsulfonylphenyl)-2-phenyl-4-(trifluoromethyl)imidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42225; 1-(4-(methylsulfonyl)phenyl]-2-phenyl-4-trifluoromethyl-1H-imidazole; 1-[4-(methylsulfonyl)phenyl]-2-phenyl-4-trifluoromethyl-1H-imidazole; SCHEMBL215075; BDBM50058001; 1-(4-Methanesulfonyl-phenyl)-2-phenyl-4-trifluoromethyl-1H-imidazole; 1-[4-(methylsulfonyl)phenyl]-2-phenyl -4-trifluoromethyl-1H-imidazole; 1-[4-(Methylsulfonyl)phenyl]-2-phenyl-4-(trifluoromethyl)-1H-imidazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 723000 nM
|
[49] | |||
| Compound Name |
Sodium;2-[3-(4-methylsulfanylphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814715
Click to Show/Hide
|
||||
| Activity |
IC50 = 758000 nM
|
[52] | |||
| Compound Name |
Acanthol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL115590; SCHEMBL12450173; BDBM50097212; [(1R,4aR,7S)-7-ethenyl-1,4a,7-trimethyl-3,4,6,8,8a,9,10,10a-octahydro-2H-phenanthren-1-yl]methanol
Click to Show/Hide
|
||||
| Activity |
IC50 = 791100 nM
|
[47] | |||
| Compound Name |
Sodium;2-[3-(4-methoxyphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1814714
Click to Show/Hide
|
||||
| Activity |
IC50 = 800000 nM
|
[52] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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| REF 3 | Experimental confirmation of new drug-target interactions predicted by Drug Profile Matching. J Med Chem. 2013 Nov 14;56(21):8377-88. | ||||
| REF 4 | Synthesis and biological evaluation of 2-phenylpyran-4-ones: a new class of orally active cyclooxygenase-2 inhibitors. J Med Chem. 2004 Jul 15;47(15):3874-86. | ||||
| REF 5 | Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhib... Bioorg Med Chem Lett. 2009 Aug 1;19(15):4504-8. | ||||
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| REF 8 | 5-Lipoxygenase-activating protein (FLAP) inhibitors. Part 4: development of 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (AM803), a potent, oral, once daily FLAP inhibitor. J Med Chem. 2011 Dec 8;54(23):8013-29. | ||||
| REF 9 | 4-(4-cycloalkyl/aryl-oxazol-5-yl)benzenesulfonamides as selective cyclooxygenase-2 inhibitors: enhancement of the selectivity by introduction of a ... J Med Chem. 2002 Mar 28;45(7):1511-7. | ||||
| REF 10 | Development of potent and selective indomethacin analogues for the inhibition of AKR1C3 (Type 5 17-hydroxysteroid dehydrogenase/prostaglandin F synthase) in castrate-resistant prostate cancer. J Med Chem. 2013 Mar 28;56(6):2429-46. | ||||
| REF 11 | Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities. Eur J Med Chem. 2017 Dec 1;141:306-321. | ||||
| REF 12 | Crystal structures of AKR1C3 containing an N-(aryl)amino-benzoate inhibitor and a bifunctional AKR1C3 inhibitor and androgen receptor antagonist. Therapeutic leads for castrate resistant prostate cancer. Bioorg Med Chem Lett. 2012 May 15;22(10):3492-7. | ||||
| REF 13 | US patent application no. 9388139B2, Derivatives of celeboxib, use thereof and preparation thereof | ||||
| REF 14 | Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity. J Med Chem. 1997 Mar 14;40(6):980-9. | ||||
| REF 15 | Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5445-8. | ||||
| REF 16 | New COX-2/5-LOX inhibitors: apoptosis-inducing agents potentially useful in prostate cancer chemotherapy. J Med Chem. 2004 Dec 2;47(25):6195-206. | ||||
| REF 17 | Synthesis and biological evaluation of 2,3-diarylthiophenes as selective cox-2 inhibitors. part II: Replacing the heterocycle. Bioorg Med Chem Lett. 1996 Jan 9;6(1):87-92. | ||||
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