Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T80896 | Target Info | |||
| Target Name | Estrogen receptor beta (ESR2) | ||||
| Synonyms |
Oestrogen receptor beta; Nuclear receptor subfamily 3 group A member 2; NR3A2; Erbeta; ESTRB; ER-beta; Beta-1
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|
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| Target Type | Successful Target | ||||
| Gene Name | ESR2 | ||||
| Biochemical Class | Nuclear hormone receptor | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 18 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Prednisolone
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|
Approved | Compound Info | ||
| Synonyms |
Nanocort; Prednisolone (injectable liposome formulation, rheumatoid arthritis); Prednisolone (injectable liposome formulation, rheumatoid arthritis), Enceladus; Prednisolone (injectable liposome formulation, rheumatoid arthritis), Galapagos
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
AZD9567
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|
Phase 1 | Compound Info | ||
| Synonyms |
ZQFNDBISEYQVRR-LOSJGSFVSA-N; AZD-9567; GTPL9812; SCHEMBL17643955; AZD 9567; example 1 [WO2016046260A1]; compound 15 [PMID: 29424542]; B9W; 2,2-difluoro-N-[(1R,2S)-3-methyl-1-[1-(1-methyl-6-oxopyridin-3-yl)indazol-5-yl]oxy-1-phenylbutan-2-yl]propanamide; 2,2-bis(fluoranyl)-~{N}-[(1~{R},2~{S})-3-methyl-1-[1-(1-methyl-6-oxidanylidene-pyridin-3-yl)indazol-5-yl]oxy-1-phenyl-butan-2-yl]propanamide
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
5,7-Dihydroxy-3-(6-oxo-1H-pyridin-3-yl)quinazolin-4-one
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|
Investigative | Compound Info | ||
| Synonyms |
3-arylquinazolinone, 1al; CHEMBL206426; SCHEMBL5120796; BDBM19921; 5,7-dihydroxy-3-(6-hydroxypyridin-3-yl)-3,4-dihydroquinazolin-4-one
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|
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| Activity |
IC50 = 51696 nM
|
[2] | |||
| Compound Name |
(4R)-1,4-Bis(4-hydroxyphenyl)azetidin-2-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3360841; BDBM50031816
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|
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| Activity |
IC50 = 56000 nM
|
[3] | |||
| Compound Name |
2-(1-Naphthylsulfonyl)-1,2,3,4-tetrahydro-6-isoquinolinol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1766964; BDBM50341437
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|
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| Activity |
EC50 = 60000 nM
|
[4] | |||
| Compound Name |
Emodin-8-glucoside
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|
Investigative | Compound Info | ||
| Synonyms |
Emodin 8-glucoside; Emodin glucoside B; Anthraglycoside B; UNII-YY0Q8Q1T3H; Emodin-8-O-beta-D-glucopyranoside; YY0Q8Q1T3H; 9,10-Anthracenedione, 1-(beta-D-glucopyranosyloxy)-3,8-dihydroxy-6-methyl-; CHEMBL464360; Emodin-8-beta-D-glucoside; NSC 257449; Glucofrangulin; Emodin-1 (8)-monoglucoside; Emodin 8-beta-D-glucoside; 3,8-Dihydroxy-6-methyl-1-anthraquinonyl-beta-D-glucopyranoside; SCHEMBL4740021; Emodin 8-O-(beta)-D-glucoside; HY-N0311; ZINC4098672; 8055AH; BDBM50366683; Glucopyranoside, 3,8-dihydroxy-6-methyl-1-anthraquinonyl-, beta-D-; LMPK13040009; MFCD01725365; AKOS037514631; MCULE-8886099883; CS-0008809; Emodin 8-glucoside, >=95% (LC/MS-UV); N2430; C10345; Q27106478; Glucopyranoside, 3,8-dihydroxy-6-methyl-1-anthraquinonyl, ..-D-; 1-beta-D-Glucopyranosyloxy-3-methyl-6-hydroxy-8-hydroxy-9,10-anthraquinone
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|
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| Activity |
IC50 = 62000 nM
|
[5] | |||
| Compound Name |
3-[(3R,3Ar,6S,7S,8R,9aS,9bS)-8-hydroxy-3-[(E,2R)-7-methoxy-6-methyl-7-oxohept-5-en-2-yl]-3a,6,9b-trimethyl-7-prop-1-en-2-yl-1,2,3,4,7,8,9,9a-octahydrocyclopenta[a]naphthalen-6-yl]propanoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2382120; BDBM50491490
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|
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| Activity |
EC50 = 72400 nM
|
[6] | |||
| Compound Name |
5-Hydroxy-3-(4-hydroxyphenyl)-7-methoxy-2-sulfanylidene-1H-quinazolin-4-one
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|
Investigative | Compound Info | ||
| Synonyms |
3-arylquinazolinone, 1aab; CHEMBL206772; SCHEMBL5117316; BDBM19935; 5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-2-sulfanyl-3,4-dihydroquinazolin-4-one
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|
||||
| Activity |
IC50 = 72848 nM
|
[2] | |||
| Compound Name |
7-Hydroxy-3-(4-hydroxyphenyl)-4-oxo-3,4-dihydroquinazoline-5-carbonitrile
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|
Investigative | Compound Info | ||
| Synonyms |
3-arylquinazolinone, 1aal; CHEMBL205717; SCHEMBL14013201; BDBM19945
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|
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| Activity |
IC50 = 73677 nM
|
[2] | |||
| Compound Name |
(+)-(2R)Kazinol I
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1083326; BDBM50320307; 5-[(2R)-7-hydroxy-3,4-dihydro-2H-chromen-2-yl]-3,4-bis(3-methylbut-2-enyl)benzene-1,2-diol
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|
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| Activity |
IC50 = 96000 nM
|
[7] | |||
| Compound Name |
Chembl4293810
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|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL18257841; BDBM50466088
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|
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| Activity |
EC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylidene]-3-hydroxynaphthalene-2-carbohydrazide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2086965; N'-(5-bromo-2-hydroxybenzylidene)-3-hydroxy-2-naphthohydrazide; ARONIS019045; SCHEMBL5995854; CHEMBL4474230; SCHEMBL16271241; BDBM50420542; STK014821; ZINC15776805; AKOS000486074; ST036491
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|
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| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
Sulfamic acid 2-adamantan-2-ylidenemethyl-benzooxazol-6-yl ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL136112; SCHEMBL6593369; BDBM50136297; [2-(2-adamantylidenemethyl)-1,3-benzoxazol-6-yl] sulfamate
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|
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| Activity |
EC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
7-Hydroxy-2-naphthyl 3-methylbenzoate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1466543; MLS001180519; HMS2825A24; ZINC365167; BDBM50389946; MCULE-6774169285; SMR000477341; AN-652/42917812
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|
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| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
7-Hydroxy-2-naphthyl 2-methoxybenzoate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1561191; MLS001180811; HMS2832H20; ZINC365151; BDBM50389947; SMR000477339
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|
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| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
N'-[(E)-(4-Hydroxy-3,5-dimethoxyphenyl)methylidene]naphtho[2,1-b]furan-2-carbohydrazide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2086964; MLS001146456; SCHEMBL14983773; BDBM50420540; STK698761; AKOS003221312; SMR000646823
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|
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| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
Benzyl-(2-isobutylamino-6-styryl-pyrimidin-4-yl)-carbamic acid tert-butyl ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493501; BDBM50253346
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|
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| Activity |
Ki = 132000 nM
|
[12] | |||
| Compound Name |
(3S,4R)-1,3-Bis(4-hydroxyphenyl)-4-(3,4,5-trimethoxyphenyl)azetidin-2-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3360849; BDBM50031815
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|
||||
| Activity |
IC50 = 144000 nM
|
[3] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 109 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N,N,N-Triisobutyl-pyrimidine-2,4,6-triamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494706; N,N,N-Triisobutyl-pyrimidine-2,4,6-triamine; BDBM50253380
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|
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| Activity |
Ki = 299000 nM
|
[12] | |||
| Compound Name |
2,4-diisobutylamino-6-isopentylpyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL347927; 2,4-diisobutylamino-6-isopentylpyrimidine; ZINC13559143; BDBM50138886
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|
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| Activity |
IC50 > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Dibenzylamino-6-isopentylpyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494121; 2,4-Dibenzylamino-6-isopentylpyrimidine
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
4-benzyl-2,6-diisobutylamino-pyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493703; 4-benzyl-2,6-diisobutylamino-pyrimidine
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
6-butyl-2,4-dipropylaminopyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL352024; 6-butyl-2,4-dipropylaminopyrimidine; BDBM50138883; ZINC13559144
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
6-ethyl-2,4-diisobutylaminopyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL484451; 6-ethyl-2,4-diisobutylaminopyrimidine
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,2,2-Trifluoro-1-(6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethanone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1766973; SCHEMBL3895230; BDBM50341442; 2,2,2-Trifluoro-1-(6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl)-ethanone; 2,2,2-trifluoro-1-(6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethanone
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|
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| Activity |
EC50 = 227000 nM
|
[4] | |||
| Compound Name |
7-Hydroxy-2,3-bis(4-hydroxyphenyl)-3,4-dihydroquinazolin-4-one
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|
Investigative | Compound Info | ||
| Synonyms |
3-arylquinazolinone, 1aag; CHEMBL425231; BDBM19940
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|
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| Activity |
IC50 = 440553 nM
|
[2] | |||
| Compound Name |
3-(((6-((5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino)methyl)benzoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1209170; SCHEMBL4283477; BDBM50323530
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|
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| Activity |
EC50 = 534000 nM
|
[13] | |||
| Compound Name |
2,4-Bis-benzylsulfanyl-6-phenethyl-pyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493713; BDBM50253416
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Benzyl-[4,6-bis-(3-met hyl-butyl)-pyrimidin-2-yl]-amine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492454; BDBM50253377
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
(4,6-Distyryl-pyrimidin-2-yl)-isobutyl-amine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523514; BDBM50253325
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N,N'',N''''-Tribenzyl-pyrimidine-2,4,6-triamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523208; BDBM50253381
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2,N4-Dimethyl-N2,N4-diisobutyl-(6-phenethyl-pyrimidin-2,4-yl)-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL522663; BDBM50253461
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Bis-benzyloxy-6-phenethyl-pyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523687; BDBM50253414
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Benzyl-6-(3-methyl-butyl)-N2-naphthalen-1-ylmethyl-pyrimidine-2,4-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523707; BDBM50253441
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4,6-Tris-benzylsulfanyl-pyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL522341; BDBM50253456
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Naphthalen-1-ylmethyl-{2-[(naphthalen-1-ylmethyl)-amino]-6-styryl-pyrimidin-4-yl}-carbamic acid tert-butyl ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL503048; BDBM50253347
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
(2-Benzylamino-6-phenethyl-pyrimidin-4-yl)-isobutyl-carbamicAcid tert-Butyl Ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL522833; BDBM50253348
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
(4,6-Diphenethyl-pyrimidin-2-yl)-naphthalen-1-ylmethyl-amine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494705; BDBM50253379
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Isobutyl-{6-(3-methyl-butyl)-2-[(naphthalen-1-ylmethyl)-amino]-pyrimidin-4-yl}-carbamic acid tert-butyl ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492297; BDBM50253361
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Benzyl-N4-naphthalen-1-ylmethyl-6-phenethyl-pyrimidine-2,4-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL495136; BDBM50253353
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Methyl-N2,N4-diisobutyl-(6-isopentyl-pyrimidin-2,4-yl)-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL445785; BDBM50253389
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N,N-Dinaphthalen-1-ylmethyl-(6-styryl-pyrimidin-2,4-yl)-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492890; BDBM50253350
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Bis-(2-methyl-propane-1-sulfonyl)-6-phenethyl-pyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493714; BDBM50253417
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
[4,6-Bis-(3-methyl-butyl)-pyrimidin-2-yl]-isobutyl-amine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492387; BDBM50253376
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
(4,6-Diphenethyl-pyrimidin-2-yl)-isobutyl-amine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494911; BDBM50253452
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Benzyl-(4,6-diphenethyl-pyrimidin-2-yl)-amine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL521859; BDBM50253453
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|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
4-N-Methyl-2-N,4-N-bis(2-methylpropyl)-6-(2-naphthalen-1-ylethyl)pyrimidine-2,4-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL495326; BDBM50253391; N4-methyl-N2,N4-diisobutyl-6-[(2-naphthalen-1-yl-ethyl)-pyrimidin-2,4-yl]-diamine
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Diisobutylamino-pyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL470153; N4,N6-diisobutylpyrimidine-4,6-diamine; BDBM50253384; N,N'-Diisobutylpyrimidine-4,6-diamine
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N,N-Dibenzyl-(6-styryl-pyrimidin-2,4-yl)-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL522206; BDBM50253392
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4,6-Tris-isobutylsulfanyl-pyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL499809; BDBM50253455
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|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2-N,4-N-Dimethyl-2-N,4-N-bis(2-methylpropyl)-6-(2-naphthalen-1-ylethyl)pyrimidine-2,4-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493904; BDBM50253460; N2,N4-dimethyl-N2,N4-diisobutyl-6-[(2-naphthalen-1-yl-ethyl)-pyrimidin-2,4-yl]-diamine
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2,N4-Dimethyl-N2,N4-diisobutyl-(6-styryl-pyrimidin-2,4-yl)-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492665; BDBM50253387
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|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Isobutyl-N4-naphthalen-1-ylmethyl-6-phenethyl-pyrimidine-2,4-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL495338; BDBM50253426
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|
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
[2-Benzylamino-6-(2-naphthalen-1-yl-ethyl)-pyrimidin-4-yl]-naphthalen-1-ylmethylcarbamic acid tert-butyl ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL447755; BDBM50253366
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|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Naphthalen-1-ylmethyl-{2-[(naphthalen-1-ylmethyl)-amino]-6-phenethyl-pyrimidin-4-yl}-carbamic acid tert-butyl ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL448274; BDBM50253419
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Methyl-N2,N4-diisobutyl-(6-phenethyl-pyrimidin-2,4-yl)-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492873; BDBM50253388
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|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Benzyl-N4-isobutyl-6-(2-naphthalen-1-yl-ethyl)-pyrimidine-2,4-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493696; BDBM50253444
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Isobutyl-6-(2-naphthalen-1-yl-ethyl)-N4-naphthalen-1-ylmethyl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493896; BDBM50253445
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2-N-Methyl-2-N,4-N-bis(2-methylpropyl)-6-(2-naphthalen-1-ylethyl)pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492874; BDBM50253464; N2,N4-methyl-N2,N4-diisobutyl-6-[(2-naphthalen-1-yl-ethyl)-pyrimidin-2,4-yl]-diamine
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Benzyl-N2-naphthalen-1-ylmethyl-6-phenethyl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL522542; BDBM50253425
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Benzyl-N4-isobutyl-6-phenethyl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL495135; BDBM50253351
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Bis-isobutylsulfanyl-6-(3-methyl-butyl)-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494122; BDBM50253356
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
4-Phenethyl-2,6-bis-phenylmethanesulfonyl-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493500; BDBM50253345
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Benzyl-6-(2-naphthalen-1-yl-ethyl)-N4-naphthalen-1-ylmethyl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL524027; BDBM50253446
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Benzyl-6-(3-methyl-butyl)-N4-naphthalen-1-ylmethyl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523041; BDBM50253443
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Benzyl-N2-naphthalen-1-ylmethyl-6-styryl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492889; BDBM50253349
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Diisobutylamino-6-chloropyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493702; BDBM50253457
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Benzyl-N2-isobutyl-6-styryl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493097; BDBM50253422
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Diisobutoxy-6-styryl-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523380; BDBM50253341
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Benzyl-(4,6-distyryl-pyrimidin-2-yl)-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523837; BDBM50253450
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Benzyl-6-(2-naphthalen-1-yl-ethyl)-N2-naphthalen-1-ylmethyl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493695; BDBM50253373
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
[2-Isobutoxy-6-(3-methyl-butyl)-pyrimidin-4-yl]-isobutylamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492262; BDBM50253467
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Benzyl-(2-isobutylamino-6-phenethyl-pyrimidin-4-yl)-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493095; BDBM50253418
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Dinaphthylen-1-ylmethylamino-6-(1-naphthylethyl)-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL502155; BDBM50253433
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Benzyl-N4-isobutyl-6-(3-methyl-butyl)-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494491; BDBM50253367
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Bis-benzylsulfanyl-6-(3-methyl-butyl)-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492483; BDBM50253358
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N,N''-Diisobutyl-2-(2-naphthalen-1-yl-ethyl)-pyrimidine-4,6-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492455; BDBM50253448
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N*2*,N*4*-Dibenzyl-6-phenethyl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL158017; BDBM50138887; N,N-Dibenzyl-(6-phenethyl-pyrimidin-2,4-yl)-diamine
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Tert-butyl N-benzyl-N-[2-(2-methylpropylamino)-6-(2-naphthalen-1-ylethyl)pyrimidin-4-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL522354; BDBM50253363; Benzyl-[2-isobutylamino-6-(2-naphthalen-1-yl-ethyl)-pyrimidin-4-yl]-carbamic acidtert-butyl ester
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2,N4-Dimethyl-N2,N4-diisobutyl-(6-isopentyl-pyrimidin-2,4-yl)-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL449931; BDBM50253386
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Tert-butyl N-[6-(3-methylbutyl)-2-(2-methylpropylamino)pyrimidin-4-yl]-N-(naphthalen-1-ylmethyl)carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL522995; BDBM50253362
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
[2-Benzylamino-6-(3-methyl-butyl)-pyrimidin-4-yl]-isobutyl-carbamic Acid tert-Butyl Ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492485; BDBM50253360
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N,N-Diisobutyl-2-(3-methyl-butyl)-pyrimidine-4,6-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493897; BDBM50253447
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4,6-Tris-benzyloxy-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494912; SCHEMBL4270551; 2,4,6-tris(phenylmethoxy)pyrimidine; BDBM50253454
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Isobutyl-[6-(3-methyl-butyl)-2-(2-methyl-propane-1-sulfonyl)-pyrimidin-4-yl]-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL507395; BDBM50253466
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Diisobutoxy-6-(3-methyl-butyl)-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493304; BDBM50253429
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Benzyl-{6-(3-methyl-butyl)-2-[(naphthalen-1-ylmethyl)-amino]-pyrimidin-4-yl}-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523698; BDBM50253355
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
[2-Isobutylamino-6-(2-naphthalen-1-yl-ethyl)-pyrimidin-4-yl]-naphthalen-1-ylmethyl-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL498951; BDBM50253365
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Bis-benzyloxy-6-(3-methyl-butyl)-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494321; BDBM50253430
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Benzylamino-6-(1-naphthylethyl)-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492684; BDBM50253432
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
[4,6-Bis-(3-methyl-butyl)-pyrimidin-2-yl]-naphthalen-1-ylmethyl-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494704; BDBM50253378
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Isobutyl-6-(3-methyl-butyl)-N2-naphthalen-1-ylmethyl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494492; BDBM50253369
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Benzyl-N2-isobutyl-6-(3-methyl-butyl)-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494493; BDBM50253440
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Dimethyl-N2,N4-diisobutyl-(6-phenethyl-pyrimidin-2,4-yl)-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492875; BDBM50253465
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Tert-butyl N-(2-methylpropyl)-N-[2-(2-methylpropylamino)-6-(2-naphthalen-1-ylethyl)pyrimidin-4-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492494; BDBM50253437; Isobutyl-[2-isobutylamino-6-(2-naphthalen-1-yl-ethyl)-pyrimidin-4-yl]-carbamicacid tert-butyl ester
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Methyl-N2,N4-diisobutyl-(6-styrylpyrimidine-2,4-yl)-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL495325; BDBM50253390
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N-Benzyl-N''-isobutyl-2-(3-methyl-butyl)-pyrimidine-4,6-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492456; BDBM50253449
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Tert-butyl N-[2-(benzylamino)-6-(2-naphthalen-1-ylethyl)pyrimidin-4-yl]-N-(2-methylpropyl)carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492693; BDBM50253438; [2-Benzylamino-6-(2-naphthalen-1-yl-ethyl)-pyrimidin-4-yl]-isobutyl-carbamic acidtert-butyl ester
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Isobutyl-6-(3-methyl-butyl)-N4-naphthalen-1-ylmethyl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494698; BDBM50253442
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Diisobutylamino-6-(1-naphthylethyl)-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL522823; BDBM50253431
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N,N-Diisobutyl-(6-phenethyl-pyrimidin-2,4-yl)-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494717; BDBM50253343
Click to Show/Hide
|
||||
| Activity |
IC50 > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Isobutyl-6-(2-naphthalen-1-yl-ethyl)-N2-naphthalen-1-ylmethyl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL522172; BDBM50253371; N4-isobutyl-6-(2-(naphthalen-1-yl)ethyl)-N2-(naphthalen-1-ylmethyl)pyrimidine-2,4-diamine
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Bis-isobutylsulfanyl-6-phenethyl-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493502; BDBM50253415
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
(4,6-Distyryl-pyrimidin-2-yl)-naphthalen-1-ylmethyl-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492657; BDBM50253451
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Methyl-N2,N4-diisobutyl-(6-styryl-pyrimidin-2,4-yl)-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL400466; BDBM50253463
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2-(3-Methylbutyl)-4-N-(2-methylpropyl)-6-N-(naphthalen-1-ylmethyl)pyrimidine-4,6-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492453; BDBM50253375; N-Isobutyl-2-(3-methyl-butyl)-N''-naphthalen-1-ylmethyl-pyrimidine-4,6-diamine
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Benzyl-N2-isobutyl-6-(2-naphthalen-1-yl-ethyl)-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493694; BDBM50253372
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Isobutyl-N2-naphthalen-1-ylmethyl-6-phenethyl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL495137; BDBM50253423
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Isobutyl-{6-(2-naphthalen-1-yl-ethyl)-2-[(naphthalen-1-ylmethyl)-amino]-pyrimidin-4-yl}-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL452996; BDBM50253439
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Isobutyl-[2-isobutylsulfanyl-6-(3-methyl-butyl)-pyrimidin-4-yl]-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492263; BDBM50253468
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Benzyl-N4-isobutyl-6-styryl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493096; BDBM50253420
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2,N4-Bis(naphthalen-1-ylmethyl)-6-phenethylpyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494319; BDBM50253427
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
4-(3-Methyl-butyl)-2,6-bis-(2-methyl-propane-1-sulfonyl)-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL521813; BDBM50253434
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Dinaphthylen-1-ylmethylamino-6-isopentylpyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494320; BDBM50253428
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Benzyl-N2-isobutyl-6-phenethyl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL495337; BDBM50253424
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Benzyl-[2-isobutylamino-6-(3-methyl-butyl)-pyrimidin-4-yl]-carbamic acid tertbutyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL523997; BDBM50253357
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Diisobutoxy-6-phenethyl-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL522032; BDBM50253413
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
4-Isobutylsulfanyl-2,6-diisobutylamino-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL443774; BDBM50253383
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
4-(3-Methyl-butyl)-2,6-bis-phenylmethanesulfonyl-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492685; BDBM50253435
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Tert-butyl N-[2-(benzylamino)-6-(3-methylbutyl)pyrimidin-4-yl]-N-(naphthalen-1-ylmethyl)carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL492493; BDBM50253436; [2-Benzylamino-6-(3-methyl-butyl)-pyrimidin-4-yl]-naphthalen-1-ylmethylcarbamicacid tert-butyl ester
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
4-Isobutoxy-2,6-diisobutylamino-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493903; BDBM50253459
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4-Bis-benzyloxy-6-styryl-pyrimidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL494716; BDBM50253342
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N4-Isobutyl-N2-naphthalen-1-ylmethyl-6-styryl-pyrimidine-2,4-diamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL524173; BDBM50253421
Click to Show/Hide
|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
2,4,6-Triisobutoxy-pyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493700; BDBM50253382
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
4-Isobutylsulfonyl-2,6-diisobutylamino-pyrimidine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493701; BDBM50253385
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|
||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
Benzyl-{6-(2-naphthalen-1-yl-ethyl)-2-[(naphthalen-1-ylmethyl)-amino]-pyrimidin-4-yl}-carbamic acid tert-butyl ester
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL443932; BDBM50253364
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| Activity |
Ki > 1000000 nM
|
[12] | |||
| Compound Name |
N2-Dimethyl-N2,N4-diisobutyl-(6-isopentyl-pyrimidin-2,4-yl)-diamine
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL451143; BDBM50253462
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||||
| Activity |
Ki > 1000000 nM
|
[12] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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| REF 3 | -Lactam estrogen receptor antagonists and a dual-targeting estrogen receptor/tubulin ligand. J Med Chem. 2014 Nov 26;57(22):9370-82. | ||||
| REF 4 | Design and evaluation of fragment-like estrogen receptor tetrahydroisoquinoline ligands from a scaffold-detection approach. J Med Chem. 2011 Apr 14;54(7):2005-11. | ||||
| REF 5 | Phytoestrogens from the roots of Polygonum cuspidatum (Polygonaceae): structure-requirement of hydroxyanthraquinones for estrogenic activity. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1839-42. | ||||
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| REF 8 | Synthesis and evaluation of 4-cycloheptylphenols as selective Estrogen receptor- agonists (SERBAs). Eur J Med Chem. 2018 Sep 5;157:791-804. | ||||
| REF 9 | "True" antiandrogens-selective non-ligand-binding pocket disruptors of androgen receptor-coactivator interactions: novel tools for prostate cancer. J Med Chem. 2012 Feb 23;55(4):1635-44. | ||||
| REF 10 | 6-(2-adamantan-2-ylidene-hydroxybenzoxazole)-O-sulfamate: a potent non-steroidal irreversible inhibitor of human steroid sulfatase. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4313-6. | ||||
| REF 11 | Discovery and structure-activity analysis of selective estrogen receptor modulators via similarity-based virtual screening. Eur J Med Chem. 2012 Aug;54:188-96. | ||||
| REF 12 | Blocking estrogen signaling after the hormone: pyrimidine-core inhibitors of estrogen receptor-coactivator binding. J Med Chem. 2008 Oct 23;51(20):6512-30. | ||||
| REF 13 | Synthesis and pharmacological validation of a novel series of non-steroidal FXR agonists. Bioorg Med Chem Lett. 2010 Aug 15;20(16):4911-7. | ||||
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