Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T87020 | Target Info | |||
| Target Name | FK506-binding protein 4 (FKBP4) | ||||
| Synonyms |
p59; Peptidyl-prolyl cis-trans isomerase FKBP4; PPIase FKBP4; P59 protein; Immunophilin FKBP52; HSP-binding immunophilin; HSP binding immunophilin; HBI; FKBP59; FKBP52 protein; FKBP52; FKBP-52; FKBP-4; 59 kDa immunophilin; 52 kDa FKBP; 52 kDa FK506-binding protein; 52 kDa FK506 binding protein
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| Target Type | Literature-reported Target | ||||
| Gene Name | FKBP4 | ||||
| Biochemical Class | Cis-trans-isomerase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 40 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Gpi-1046
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|
Terminated | Compound Info | ||
| Synonyms |
186452-09-5; gpi-1046; (S)-3-(Pyridin-3-yl)propyl 1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate; CHEMBL6367; L-Proline, 1-(3,3-dimethyl-1,2-dioxopentyl)-, 3-(3-pyridinyl)propyl ester; (2S)-[3-PYRIDYL-1-PROPYL]-1-[3,3-DIMETHYL-1,2-DIOXOPENTYL]-2-PYRROLIDINECARBOXYLATE; 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate; 3-(pyridin-3-yl)propyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate; GPI; AC1L9I3R; SCHEMBL4766380; BDBM23334; CTK0I3903; DTXSID00332191
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[3-[(1R)-1-[(2S)-1-[(2S)-2-Cyclohexyl-2-(3,5-dimethoxyphenyl)acetyl]piperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623613; BDBM50125332
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| Activity |
Ki ~ 50000 nM
|
[2] | |||
| Compound Name |
CID 57522929
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058795; BDBM50388299
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| Activity |
IC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
CID 57522803
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058793; SCHEMBL15062392; BDBM50388297
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|
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| Activity |
IC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
SAFit1
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623612; SCHEMBL16586338; BDBM50125333; HY-102079; CS-0022958
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| Activity |
Ki ~ 50000 nM
|
[2] | |||
| Compound Name |
CID 57522802
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058792; BDBM50388296
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| Activity |
IC50 ~ 50000 nM
|
[3] | |||
| Compound Name |
CID 57522683
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058787; SCHEMBL15062535; BDBM50388293
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|
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| Activity |
IC50 = 66500 nM
|
[3] | |||
| Compound Name |
CID 57522008
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058227; SCHEMBL15062631; BDBM50388276
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| Activity |
IC50 = 69900 nM
|
[3] | |||
| Compound Name |
CID 57522237
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058232; SCHEMBL15062413; BDBM50388278
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| Activity |
IC50 = 84500 nM
|
[3] | |||
| Compound Name |
4,4-Dimethyl-6,17-dioxa-1-azabicyclo[17.4.0]tricosane-2,3,7,18-tetrone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL320252; BDBM50283391; 7,7-Dimethyl-tetradecahydro-9,20-dioxa-4a-aza-benzocyclononadecene-5,6,10,21-tetraone
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| Activity |
Ki = 90000 nM
|
[4] | |||
| Compound Name |
2-[3-[(1R)-1-[(2S)-1-[(2S)-2-Cyclohexyl-2-(3-methoxyphenyl)acetyl]piperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623614; BDBM50125331
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|
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| Activity |
Ki ~ 100000 nM
|
[2] | |||
| Compound Name |
2-[3-[(1R)-1-[(2S)-1-(1-Benzothiophen-2-ylsulfonyl)piperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058226; SCHEMBL15069778; BDBM50388275
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-(3,5-dichlorophenyl)sulfonylpiperidine-2-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058790; BDBM50388294
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-[3-[(1R)-1-[(2S)-1-(3,4-Dichlorophenyl)sulfonylpiperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058235; BDBM50388281
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-[3-[3-(3,4-Dimethoxyphenyl)-1-[[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carbonyl]amino]propyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058804; BDBM50388306
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[(3R)-4-(3,3-dimethyl-2-oxopentanoyl)thiomorpholine-3-carbonyl]oxypropyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058803; BDBM50388305
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
CID 57522347
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058236; SCHEMBL15062624; BDBM50388282
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
CID 57522570
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058499; SCHEMBL15062747; BDBM50388292
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[(2S)-1-pyrimidin-4-ylsulfonylpiperidine-2-carbonyl]oxypropyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058231; BDBM50388277
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Timcodar
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Investigative | Compound Info | ||
| Synonyms |
vx-853; UNII-U141W322WZ; U141W322WZ; VX853; Timcodar [INN]; VX 853; SCHEMBL3673444; CHEMBL2059028; GTPL10868; BDBM50388313; DB12761; Q27290544
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-(1,3-benzothiazol-6-ylsulfonyl)piperidine-2-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058791; BDBM50388295
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
CID 57522685
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058789; SCHEMBL15062446; BDBM50388264
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
CID 57521881
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058222; SCHEMBL15063118; BDBM50388271
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
CID 57522684
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058788; SCHEMBL15062388; BDBM50388302
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2059023; SCHEMBL14920841; BDBM50388308
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-[2-[(1S,2R)-2-ethyl-1-hydroxycyclohexyl]-2-oxoacetyl]piperidine-2-carboxylate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2059032; BDBM50388317
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-[3-[(1R)-1-[(2S)-1-[3,5-Bis(methoxycarbonyl)phenyl]sulfonylpiperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2057219; SCHEMBL15062619; BDBM50388287
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
CID 57522121
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058229; SCHEMBL15062497; BDBM50388301
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[(2S)-1-(2-methylpyrimidin-4-yl)sulfonylpiperidine-2-carbonyl]oxypropyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058230; BDBM50388263
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[(2S)-1-(3-nitrophenyl)sulfonylpiperidine-2-carbonyl]oxypropyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058228; SCHEMBL15069766; BDBM50388265
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-[3-[(1R)-1-[(2S)-1-[3,5-Bis(trifluoromethyl)phenyl]sulfonylpiperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058239; SCHEMBL15062453; BDBM50388285
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-[3-[(1R)-1-[(2S)-1-[3-Bromo-5-(trifluoromethyl)phenyl]sulfonylpiperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058240; SCHEMBL15062428; BDBM50388286
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-[3-[(1R)-1-[[(2S)-1-(3,5-Dichloro-4-hydroxyphenyl)sulfonylpiperidine-2-carbonyl]amino]-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058798; BDBM50388268
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[[(2S)-1-[(2-oxo-3H-1,3-benzothiazol-6-yl)sulfonyl]piperidine-2-carbonyl]amino]propyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058799; BDBM50388269
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|
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(21S)-1Aza-4,4-dimethyl-6,19-dioxa-2,3,7,20-tetraoxobicyclo[19.4.0] pentacosane
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1235837; SCHEMBL5966237; BDBM50403328; DB08520; Q27097719; (21S)-4,4-Dimethyl-6,19-dioxa-1-azabicyclo[19.4.0]pentacosane-2,3,7,20-tetraone
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| Activity |
Ki = 100000 nM
|
[4] | |||
| Compound Name |
CID 57522006
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058225; SCHEMBL15062495; BDBM50388274
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Methyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2058805; SCHEMBL1776165; BDBM50388307
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
2-(3,4-Dimethoxyphenyl)ethyl (2S)-1-[2-[(1S,2R)-1-hydroxy-2-methylcyclohexyl]-2-oxoacetyl]piperidine-2-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2059030; BDBM50388315
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|
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| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
(S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL129537; BDBM50067003; (2S)-1-(1,2-Dioxo-3,3-dimethylpentyl)piperidine-2alpha-carboxylic acid 3-(3-pyridinyl)propyl ester
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| Activity |
IC50 ~ 150000 nM
|
[1] | |||
| Compound Name |
18-(2-Cyclohexylethyl)-4,4-dimethyl-6,19-dioxa-1-azabicyclo[19.4.0]pentacosane-2,3,7,20-tetrone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL109676; BDBM50283390
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| Activity |
Ki = 190000 nM
|
[4] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 16 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
1-[3-[[(2S)-2-Acetamidopropanoyl]amino]-2-oxopropanoyl]-N-[(2S)-1-(4-nitroanilino)-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL126349; BDBM50118069
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| Activity |
IC50 = 215000 nM
|
[5] | |||
| Compound Name |
4,4-Dimethyl-6,19-dioxa-1-azabicyclo[19.4.0]pentacosane-2,3,7,20-tetrone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL109750; SCHEMBL5158007; BDBM50283388; 1,19-(1,2-Piperidinediyl)-3,3-dimethyl-5,18-dioxanonadecane-1,2,6,19-tetraone; 7,7-Dimethyl-hexadecahydro-9,22-dioxa-4a-aza-benzocyclohenicosene-5,6,10,23-tetraone
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| Activity |
Ki = 290000 nM
|
[4] | |||
| Compound Name |
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S,3S)-3-methyl-1-oxo-1-(2-phenylethylamino)pentan-2-yl]pyrrolidine-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790321; BDBM50369809
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|
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| Activity |
IC50 = 325000 nM
|
[6] | |||
| Compound Name |
(8E,10Z)-4,4-Dimethyl-6,19-dioxa-1-azabicyclo[19.4.0]pentacosa-8,10-diene-2,3,7,20-tetrone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL111188; BDBM50283387
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| Activity |
Ki = 340000 nM
|
[4] | |||
| Compound Name |
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S,3S)-1-(2,2-diphenylethylamino)-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790320; BDBM50369810
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|
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| Activity |
IC50 = 365000 nM
|
[6] | |||
| Compound Name |
2-[3-[(1R)-1-[(2S)-1-[(2S)-2-Cyclohexyl-2-phenylacetyl]piperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623615; BDBM50125329
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|
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| Activity |
Ki > 500000 nM
|
[2] | |||
| Compound Name |
2-[3-[(1R)-1-[(2S)-1-[(2R)-2-Cyclohexylpent-4-enoyl]piperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623616; SCHEMBL16585966; BDBM50125328
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| Activity |
Ki > 500000 nM
|
[2] | |||
| Compound Name |
N-Succinyl-ala-ala-pro-phe-p-nitroanilide
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Investigative | Compound Info | ||
| Synonyms |
Suc-aapf-pna; N-Succinyl-Ala-Ala-Pro-Phe-pNA; N-Succinyl-Ala-Ala-Pro-Phe p-nitroanilide; CHEMBL298712; Cathepsin g substrate I,colorimetric; Suc-Ala-Ala-Pro-Phe-p-nitroanilide; Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide; N-Suc-Ala-Ala-Pro-Phe-pNA; succinyl-Ala-Ala-Pro-Phe p-nitroanilide; N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine p-nitroanilide; succinyl-L-Ala-L-Ala-L-Pro-L-Phe-p-nitroanilide; N-succinyl-L-Ala-L-Ala-L-Pro-L-Phe-p-nitroanilide; N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide; Suc-Ala-Ala-Pro-Phe-p-NA; succinyl-Ala-Ala-Pro-Phe-pNA; C30H36N6O9; 1004AC; BDBM50087877; MFCD00077161; ZINC29464478; N-Suc-Ala-Ala-Pro-Phe-p-nitroanilide; Succinyl-Ala-Ala-Pro-Phe-4-nitroanilide; N-succinyl-l-Ala-Ala-Pro-Phe-p-nitroanilide; succinyl-L-Ala-L-Ala-L-Pro-L-Phe p-nitroanilide; Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide - CAS 70967-97-4
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| Activity |
IC50 = 540000 nM
|
[5] | |||
| Compound Name |
(2S)-1-[(2R)-2-[[(2S)-2-Acetamidopropanoyl]amino]propanoyl]-N-[(2S)-1-(4-nitroanilino)-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2370636
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|
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| Activity |
IC50 = 640000 nM
|
[5] | |||
| Compound Name |
(8E,10E)-4,4-Dimethyl-6,19-dioxa-1-azabicyclo[19.4.0]pentacosa-8,10-diene-2,3,7,20-tetrone
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL111691; BDBM50283389
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|
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| Activity |
Ki = 840000 nM
|
[4] | |||
| Compound Name |
2-[3-[(1R)-1-[(2S)-1-[(2R)-2-Cyclohexylpropanoyl]piperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623617; SCHEMBL16586196; BDBM50125327
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|
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| Activity |
Ki > 1000000 nM
|
[2] | |||
| Compound Name |
Suc-Ala-Gly-Pro-Phe-pNA
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL125967; BDBM50118071; MFCD00238369; ZINC27307277
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|
||||
| Activity |
IC50 = 1450000 nM
|
[5] | |||
| Compound Name |
4,4-Dimethyl-6,11-dioxa-1-azabicyclo[11.4.0]heptadecane-2,3,7,12-tetrone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL419746; BDBM50283392; 7,7-Dimethyl-octahydro-9,14-dioxa-4a-aza-benzocyclotridecene-5,6,10,15-tetraone
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| Activity |
Ki = 2900000 nM
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[4] | |||
| Compound Name |
N-{1-[(Ethoxy-{2-[1-(4-nitro-phenylcarbamoyl)-2-phenyl-ethylcarbamoyl]-pyrrolidin-1-yl}-phosphinoylmethyl)-carbamoyl]-ethyl}-succinamic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL126888; BDBM50118067
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| Activity |
IC50 = 5400000 nM
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[5] | |||
| Compound Name |
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-methylbutanoyl]amino]-5-aminopentanoyl]amino]propanoyl]amino]acetyl]-N-[(2R,3R)-1-[[(2R)-1-amino-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL295941; BDBM50087861
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| Activity |
IC50 > 10000000 nM
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[6] | |||
| Compound Name |
4,4-Dimethyl-6,23-dioxa-1-azabicyclo[23.4.0]nonacosane-2,3,7,24-tetrone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL324019; BDBM50283386; 7,7-Dimethyl-icosahydro-9,26-dioxa-4a-aza-benzocyclopentacosene-5,6,10,27-tetraone
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| Activity |
Ki = 11000000 nM
|
[4] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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| REF 1 | Evaluation of synthetic FK506 analogues as ligands for the FK506-binding proteins 51 and 52. J Med Chem. 2012 May 10;55(9):4114-22. | ||||
| REF 2 | Structure-Affinity Relationship Analysis of Selective FKBP51 Ligands. J Med Chem. 2015 Oct 8;58(19):7796-806. | ||||
| REF 3 | Exploration of pipecolate sulfonamides as binders of the FK506-binding proteins 51 and 52. J Med Chem. 2012 May 10;55(9):4123-31. | ||||
| REF 4 | Synthesis and structure-activity relationships of macrocyclic FKBP ligands. Bioorg Med Chem Lett. 1994 Jan 20;4(2):321-4. | ||||
| REF 5 | Synthesis and evaluation of Glypsi(PO(2)R-N)Pro-containing pseudopeptides as novel inhibitors of the human cyclophilin hCyp-18. J Med Chem. 2002 Aug 29;45(18):3928-33. | ||||
| REF 6 | Design of a Gag pentapeptide analogue that binds human cyclophilin A more efficiently than the entire capsid protein: new insights for the development of novel anti-HIV-1 drugs. J Med Chem. 2000 May 4;43(9):1770-9. | ||||
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