Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T94033 | Target Info | |||
| Target Name | Coagulation factor IIa (F2) | ||||
| Synonyms |
Prothrombin; Coagulation factor II
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| Target Type | Successful Target | ||||
| Gene Name | F2 | ||||
| Biochemical Class | Peptidase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 450 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
L-694,458
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|
Phase 2 | Compound Info | ||
| Synonyms |
DMP 777; 157341-41-8; DMP-777; UNII-3Q0469283P; (S)-N-((R)-1-(Benzo[d][1,3]dioxol-5-yl)butyl)-3,3-diethyl-2-(4-(4-methylpiperazine-1-carbonyl)phenoxy)-4-oxoazetidine-1-carboxamide; DMP777; CHEMBL310871; L-694458; 3Q0469283P; (S)-N-((R)-1-(Benzo[d][1,3]dioxol-5-yl)butyl)-3,3-diethyl-2-(4-(4methyl-piperazine-1-carbonyl)phenoxy)-4-oxoazetidine-1-carboxamide (3.5% w/w solution); L-694,458; L 694458; SCHEMBL6538142; AC1L433D; CTK4C9348; DTXSID00166251; MolPort-023-332-820; C31H40N4O6; ZINC3936307; KS-00001E6Q; BCP02269
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| Activity |
IC50 = 78760 nM
|
[1] | |||
| Compound Name |
EPICATECHIN
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Phase 2 | Compound Info | ||
| Synonyms |
(-)-Epicatechin; Epicatechin; 490-46-0; L-Epicatechin; (-)-Epicatechol; l-Acacatechin; (2R,3R)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol; Epicatechol; l-Epicatechol; (-)epicatechin; (2R,3R)-(-)-Epicatechin; UNII-34PHS7TU43; epi-Catechin; epi-Catechol; CCRIS 7097; EINECS 207-710-1; NSC 81161; Epicatechol, (-)-; CHEBI:90; 34PHS7TU43; PFTAWBLQPZVEMU-UKRRQHHQSA-N; (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol; (-)-(2R:3R)-5,7,3',4'-Tetrahydroxyflavan-3-ol; AK105372; C15H14O6
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| Activity |
IC50 = 150000 nM
|
[2] | |||
| Compound Name |
YM60828
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Terminated | Compound Info | ||
| Synonyms |
YM-60828; YM 60828; 201933-41-7; CHEMBL20240; 179755-65-8; {[(7-Carbamimidoylnaphthalen-2-Yl)methyl][4-({1-[(1e)-Ethanimidoyl]piperidin-4-Yl}oxy)phenyl]sulfamoyl}acetic Acid; SCHEMBL676753; DTXSID80430967; ZINC3952416; BDBM50084617; ACM179755658; KB-81529; FT-0675886; 2-[[[[7-(Aminoiminomethyl)-2-naphthalenyl]methyl][4-[[1-(1-iminoethyl)-4-piperidinyl]oxy]phenyl]amino]sulfonyl]acetic Acid Dihydrochloride; [[4-[(1-Acetimidoylpiperidin-4-yl)oxy]phenyl][(7-amidino-2-naphthyl)methyl]sulfamoyl]acetic acid; 0CB
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| Activity |
Ki ~ 100000 nM
|
[3] | |||
| Compound Name |
6-(N-Phenylcarbamyl)-2-Naphthalenecarboxamidine
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Investigative | Compound Info | ||
| Synonyms |
6-(N-PHENYLCARBAMYL)-2-NAPHTHALENECARBOXAMIDINE; CHEMBL104937; 6-[(Z)-AMINO(IMINO)METHYL]-N-PHENYL-2-NAPHTHAMIDE; 6-carbamimidoyl-N-phenylnaphthalene-2-carboxamide; 1owe; uPa_7; AC1L9L6A; SCHEMBL4324160; ZINC2047486; BDBM50138670; 6-carbamimidoyl-N-phenyl-2-naphthamide; DB01977; 6-Carbamimidoyl-naphthalene-2-carboxylic acid phenylamide
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| Activity |
IC50 = 56000 nM
|
[4] | |||
| Compound Name |
Piperidine-1-carboxamidine
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Investigative | Compound Info | ||
| Synonyms |
Piperidine-1-carboxamidine; piperidine-1-carboximidamide; 4705-39-9; 1-Piperidinecarboximidamide; piperidinecarboxamidine; 1-(aminoiminomethyl)-; CHEMBL103102; amidinopiperdine; amidinopiperidine; MRZ; AC1L4DUO; AC1Q4YZ7; SCHEMBL1228214; CTK4I9701; DTXSID50276834; MolPort-000-511-098; QUUYRYYUKNNNNS-UHFFFAOYSA-N; ZINC159755; SBB079071; HTS003411; BDBM50037981; STK210669; BBL015601; AKOS000225517; MCULE-4074763290; SC-65494; AJ-15523; Piperidine-1-Carboximidamide Hydrobromide; KB-275095; DB-070770; FT-0742354; ST50161491
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| Activity |
Ki = 111000 nM
|
[5] | |||
| Compound Name |
CATECHIN
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Investigative | Compound Info | ||
| Synonyms |
Cianidanol; (+)-catechin; 154-23-4; Catechuic acid; Cyanidanol; Catechinic acid; D-Catechin; Catergen; Cianidol; (+)-Cyanidanol; (+)-Cyanidan-3-ol; Biocatechin; (+)-Catechin Hydrate; D-(+)-Catechin; Dexcyanidanol; Catechin (flavan); Catechol (flavan); D-Catechol; (2R,3S)-Catechin; (2R,3S)-2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol; Gambier; 3-Cyanidanol, (+)-; Cianidanolum; Catechu; Transepar; Katha; (2R,3S)-(+)-Catechin; Cutch (dye); (+)-Cianidanol; 3,3',4',5,7-Flavanpentol; KB-53; (+)-Cyanidanol-3; CCRIS 6855
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| Activity |
IC50 = 125000 nM
|
[2] | |||
| Compound Name |
3-Carboxamide-coumarin deriv., 34
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL494978; BDBM23564; ZINC40955680; N-(3,5-dimethylphenyl)-6-methyl-2-oxo-2H-chromene-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(R)-N-{(S)-2-(4-Cyano-phenyl)-1-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-ethyl}-3-phenyl-2-phenylmethanesulfonylamino-propionamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL77142; BDBM50130054; 2-[N-(Benzylsulfonyl)-D-Phe-4-cyano-L-Phe-L-Arg-]thiazole
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| Activity |
IC50 = 50000 nM
|
[7] | |||
| Compound Name |
2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-(1-methyl-1-phenyl-ethyl)-acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL36001; BDBM50126568
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| Activity |
Ki ~ 50000 nM
|
[8] | |||
| Compound Name |
6-Fluoro-2-[2-hydroxy-3-(pyrrolidin-3-yloxy)-phenyl]-1H-benzoimidazole-5-carboxamidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL61791; BDBM50115863
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| Activity |
Ki = 50000 nM
|
[9] | |||
| Compound Name |
(3S)-N-[1-[[(2R)-Butan-2-yl]amino]-1,2-dioxohexan-3-yl]-2-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL184715; BDBM50152748
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| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
2-Ketobenzothiazole 22
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL175599; SCHEMBL8667159; BDBM14082; N-[1-(1,3-benzothiazol-2-yl)-5-carbamimidamido-1-oxopentan-2-yl]formamide
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| Activity |
IC50 ~ 50000 nM
|
[11] | |||
| Compound Name |
3-Carboxamide-coumarin deriv., 43
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL521526; BDBM23566; 6,8-dichloro-N-(3,5-dimethylphenyl)-2-oxo-2H-chromene-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
3-Carboxamide-coumarin deriv., 46
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL495155; BDBM23568; 8-bromo-6-chloro-N-(3,5-dimethylphenyl)-2-oxo-2H-chromene-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(2R)-2-[[(2R)-2-[[2-[[2-[[2-[[(2S)-2-[[(1R,7S,10S,13S,16S,22S,25S,28S,40R,43S,46S,49S,52S,58S,61S)-40-Acetamido-43,52-bis(2-amino-2-oxoethyl)-13-(carboxymethyl)-46-[(1R)-1-hydroxyethyl]-10,49,61-tris(1H-indol-3-ylmethyl)-16-methyl-25-(2-methylpropyl)-2,8,11,14,17,23,26,41,44,47,50,53,59,62-tetradecaoxo-30,38,65-trithia-3,9,12,15,18,24,27,42,45,48,51,54,60,63-tetradecazahexacyclo[32.29.3.132,36.03,7.018,22.054,58]heptahexaconta-32,34,36(67)-triene-28-carbonyl]amino]propanoyl]-methylamino]acetyl]-methylamino]acetyl]-methylamino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4059991; BDBM50256261
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| Activity |
Ki ~ 50000 nM
|
[12] | |||
| Compound Name |
Chembl4208878
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Investigative | Compound Info | ||
| Synonyms |
BDBM50459529
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| Activity |
IC50 ~ 50000 nM
|
[13] | |||
| Compound Name |
Chembl365415
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2371797; BDBM50152752
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| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
2-(2-{2-Cyclohexyl-2-[(pyrazine-2-carbonyl)-amino]-acetylamino}-3,3-dimethyl-butyryl)-octahydro-cyclopenta[c]pyrrole-1-carboxylic acid (1-cyclopropylaminooxalyl-3,3-difluoro-propyl)-amide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL414805; BDBM50152750
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| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
3-Carboxamide-coumarin deriv., 30
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL522532; BDBM23560; ZINC40955216; 6-methyl-N-(4-methylphenyl)-2-oxo-2H-chromene-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(2S)-2-(Benzylsulfonylamino)-5-(diaminomethylideneamino)-N-[2-[[5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]pentanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL40764; BDBM50084010
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| Activity |
IC50 = 50000 nM
|
[14] | |||
| Compound Name |
3-Carboxamide-coumarin deriv., 26
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL523874; BDBM23541; 6-methyl-N-(naphthalen-1-ylmethyl)-2-oxo-2H-chromene-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
6-Methyl-N-(3-methylphenyl)-2-oxo-2H-chromene-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL494808; BDBM23559; 3-Carboxamide-coumarin deriv., 29; ZINC40431053
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
N-[1-(4-Acetylamino-phenyl)-ethyl]-2-[3-(4-carbamimidoyl-phenyl)-ureido]-acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL122863; BDBM50148948
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| Activity |
Ki ~ 50000 nM
|
[15] | |||
| Compound Name |
(2S)-2-[[(3S,9S,12S,15S,18S,21R,26R,29S,32S)-21-[[(2S)-2-[(2-Aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]-15-(4-aminobutyl)-9-(carboxymethyl)-29-[3-(diaminomethylideneamino)propyl]-18-[(1R)-1-hydroxyethyl]-12-(hydroxymethyl)-2,8,11,14,17,20,28,31-octaoxo-23,24-dithia-1,7,10,13,16,19,27,30-octazatricyclo[30.3.0.03,7]pentatriacontane-26-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623789; BDBM50125047
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| Activity |
Ki ~ 50000 nM
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[16] | |||
| Compound Name |
6-Fluoro-2-[2-hydroxy-3-(piperidin-3-ylmethoxy)-phenyl]-1H-benzoimidazole-5-carboxamidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL303978; BDBM50115854
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| Activity |
Ki = 50000 nM
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[9] | |||
| Compound Name |
(-)-Trypethelone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1835011; BDBM50355306; Q27137378
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| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
(7R,10S,13S,21S,24S,27S,30S,33S,36S,39S,42S,45R)-7-Acetamido-36-(3-amino-3-oxopropyl)-13-benzyl-24-(4-carbamimidamidobutyl)-39-(carboxymethyl)-10-(hydroxymethyl)-21-[(4-hydroxyphenyl)methyl]-33-(1H-imidazol-5-ylmethyl)-30-methyl-42-(2-methylpropyl)-8,11,14,19,22,25,28,34,37,40,43-undecaoxo-5,47,52-trithia-9,12,15,20,23,26,29,32,35,38,41,44-dodecazatetracyclo[25.23.3.13,49.015,18]tetrapentaconta-1,3(54),49-triene-45-carboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4094403; BDBM50256260
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| Activity |
Ki ~ 50000 nM
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[12] | |||
| Compound Name |
3-Oxo-N-phenyl-3H-benzo[f]chromene-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
Oprea1_332334; Oprea1_401977; CHEMBL495038; 3-Oxo-3H-benzo[f]chromene-2-carboxylic acid phenylamide; BDBM23551; 3-Carboxamide-coumarin deriv., 48; STK042072; ZINC12062408; AKOS000511888; CCG-311417; MCULE-4505918310; EU-0036469; SR-01000416840; SR-01000416840-1
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
Chembl364471
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2371795; BDBM50152753
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| Activity |
Ki ~ 50000 nM
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[10] | |||
| Compound Name |
3-Carboxamide-coumarin deriv., 28
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL502858; BDBM23558; ZINC40424127; 6-methyl-N-(2-methylphenyl)-2-oxo-2H-chromene-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
3-Carboxamide-coumarin deriv., 4
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Investigative | Compound Info | ||
| Synonyms |
NSC716527; CHEMBL274376; BDBM23544; NSC-716527; NCI60_040288; 6-(chloromethyl)-2-oxo-N-phenyl-2H-chromene-3-carboxamide; 6-Chloromethyl-N-phenyl-2-oxo-2H-1-benzopyran-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2-(Benzothiazole-2-ylthiomethyl)-5-(pivaloyloxy)-4H-pyran-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3093815; BDBM50444297
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| Activity |
IC50 ~ 50000 nM
|
[18] | |||
| Compound Name |
2-(5-Carboxybenzoxazole-2-ylthiomethyl)-5-(pivaloyloxy)-4H-pyran-4-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3093814; BDBM50444296
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| Activity |
IC50 ~ 50000 nM
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[18] | |||
| Compound Name |
3-Carboxamide-coumarin deriv., 33
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL494800; BDBM23557; ZINC40954603; N-(4-chlorophenyl)-6-methyl-2-oxo-2H-chromene-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(2S)-2-[[(3S,9S,12S,15S,18S,21R,26R,29S,32S)-21-[[(2S)-2-[(2-Aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]-15-(4-aminobutyl)-9-[(2S)-butan-2-yl]-29-[3-(diaminomethylideneamino)propyl]-18-[(1R)-1-hydroxyethyl]-12-(hydroxymethyl)-2,8,11,14,17,20,28,31-octaoxo-23,24-dithia-1,7,10,13,16,19,27,30-octazatricyclo[30.3.0.03,7]pentatriacontane-26-carbonyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3623788; BDBM50125048
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| Activity |
Ki ~ 50000 nM
|
[16] | |||
| Compound Name |
3-Carboxamide-coumarin deriv., 20
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL495466; BDBM23538; ZINC38816294; 6-methyl-2-oxo-N-phenyl-2H-chromene-3-carboxamide; 2-Oxo-N-phenyl-6-methyl-2H-1-benzopyran-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(3S)-2-[(2S)-2-[[(2S)-2-Cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[1,2-dioxo-1-[[(1R)-1-phenylethyl]amino]hexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL184035; BDBM50152751
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| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
3-Carboxamide-coumarin deriv., 31
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL495225; BDBM23555; ZINC40953963; N-(2-chlorophenyl)-6-methyl-2-oxo-2H-chromene-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(S)-N-((1-Carbamimidoylpiperidin-4-yl)methyl)-5-guanidino-2-((S)-2-((S)-5-guanidino-2-(2-phenylacetamido)pentanamido)-3-methylbutanamido)pentanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL568067; BDBM50303778
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| Activity |
Ki = 50000 nM
|
[19] | |||
| Compound Name |
3,5-Bis-[1-(4-carbamimidoyl-phenyl)-meth-(Z)-ylidene]-4-oxo-cyclohexanecarboxylic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL151164; SCHEMBL7440607; BDBM50084170
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| Activity |
Ki ~ 50000 nM
|
[20] | |||
| Compound Name |
(-)-Cereoaldomine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1835012; BDBM50355307; Q27137379
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| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
3-Carboxamide-coumarin deriv., 45
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL495154; BDBM23567; 8-bromo-6-chloro-N-(3-methylphenyl)-2-oxo-2H-chromene-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
5-Methylsulfanyl-4-[4-(5-propoxy-1-pyridin-2-yl-1H-pyrazol-4-yl)-thiazol-2-yl]-thiophene-2-carboxamidine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL317917; BDBM50147046
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| Activity |
Ki ~ 50000 nM
|
[21] | |||
| Compound Name |
(3S,3As,6aR)-2-[(2S)-2-[[(2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetyl]amino]-3,3-dimethylbutanoyl]-N-[1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
VX-950, Telaprevir; CHEMBL443336; CYC142; SCHEMBL1709083; SCHEMBL16556602; CTK5A5985; DTXSID00389004; AKOS015896277; AC-5241; AB01566825_01
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| Activity |
Ki ~ 50000 nM
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[10] | |||
| Compound Name |
Chembl184525
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2371796; BDBM50152755
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
7-Hydroxy-2-oxo-N-phenyl-2H-1-benzopyran-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
7-hydroxy-2-oxo-N-phenyl-2H-chromene-3-carboxamide; EINECS 302-422-3; 7-hydroxy-2-oxo-N-phenylchromene-3-carboxamide; Oprea1_567475; Oprea1_613532; CHEMBL508427; SCHEMBL10980649; BDBM23552; CTK5H5054; DTXSID10240591; ZINC193181; 3-Carboxamide-coumarin deriv., 37; STK057369; AKOS000511885; MCULE-8391530313; NCGC00343225-01; EU-0034812; AB00124768-02; SR-01000400262; SR-01000400262-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
N-[(3-Bromophenyl)methyl]-2-[(4-carbamimidoylphenyl)carbamoylamino]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL287473; SCHEMBL236558; BDBM50126573; N-(3-Bromo-benzyl)-2-[3-(4-carbamimidoyl-phenyl)-ureido]-acetamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[8] | |||
| Compound Name |
Chembl4162159
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50449676
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[22] | |||
| Compound Name |
(3S,3As,6aR)-N-[1-(cyclopropylamino)-1,2-dioxohexan-3-yl]-2-[(2S)-3,3-dimethyl-2-[[(2S)-3-methyl-2-(pyrazine-2-carbonylamino)butanoyl]amino]butanoyl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL315390; SCHEMBL13091808; BDBM50137739
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[10] | |||
| Compound Name |
(-)-Cereolactam
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1835010; BDBM50355305; Q27137377
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[17] | |||
| Compound Name |
3-Carboxamide-coumarin deriv., 47
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493602; BDBM23549; 6-bromo-8-methoxy-2-oxo-N-phenyl-2H-chromene-3-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-((R)-1-phenyl-ethyl)-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL36341; BDBM50126569
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[8] | |||
| Compound Name |
(2R)-2-[[(2R)-2-[[2-[[2-[[2-[[(2S)-2-[[(7R,10S,13S,16S,22S,25S,28S,31R,34S,37S,45S,48S,51R)-51-Acetamido-45-benzyl-10-[(2S)-butan-2-yl]-34-(4-carbamimidamidobutyl)-13-(carboxymethyl)-48-(hydroxymethyl)-22,25,37-tris[(4-hydroxyphenyl)methyl]-9,12,15,21,24,27,30,33,36,39,44,47,50-tridecaoxo-28-propan-2-yl-5,53,58-trithia-8,11,14,20,23,26,29,32,35,38,43,46,49-tridecazapentacyclo[29.25.3.13,55.016,20.040,43]hexaconta-1(56),2,55(60)-triene-7-carbonyl]amino]propanoyl]-methylamino]acetyl]-methylamino]acetyl]-methylamino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4070056; BDBM50256262
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[12] | |||
| Compound Name |
2-{(S)-2-[((S)-1-{(S)-2-[4-(4-Chloro-benzenesulfonylaminocarbonyl)-benzoylamino]-3-methyl-butyryl}-pyrrolidine-2-carbonyl)-amino]-3-methyl-butyryl}-benzooxazole-5-carboxylic acid amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL419985; BDBM50031187
Click to Show/Hide
|
||||
| Activity |
Ki ~ 50000 nM
|
[23] | |||
| Compound Name |
7-Methoxy-2-oxo-N-phenyl-2H-chromene-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Oprea1_813820; CHEMBL447503; BDBM23553; ZINC192815; 3-Carboxamide-coumarin deriv., 38; STL376493; AKOS000415407; MCULE-1646989031; ST066313; (7-methoxy-2-oxochromen-3-yl)-N-benzamide; SR-01000399886; SR-01000399886-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2-[3-(4-Carbamimidoyl-phenyl)-ureido]-N-((S)-1-phenyl-ethyl)-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL36002; SCHEMBL235788; BDBM50126585
Click to Show/Hide
|
||||
| Activity |
Ki = 50700 nM
|
[15] | |||
| Compound Name |
Chembl44612
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372759; BDBM50070705
Click to Show/Hide
|
||||
| Activity |
IC50 = 51000 nM
|
[24] | |||
| Compound Name |
1,4-Di{4-[5-amino(imino)methylbenzo[b]furan-2-ylcarbonyl]hexahydro-1-pyrazinyl}-1,4-butanedione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL109251; BDBM50083543; 2,2'-[1,4-Dioxobutane-1,4-diylbis(piperazine-4,1-diylcarbonyl)]bis(benzofuran-5-carboxamidine)
Click to Show/Hide
|
||||
| Activity |
Ki = 51000 nM
|
[25] | |||
| Compound Name |
4-[[2-[(3-Carbamimidoylphenyl)sulfonylamino]acetyl]amino]benzoic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159301
Click to Show/Hide
|
||||
| Activity |
Ki = 52000 nM
|
[26] | |||
| Compound Name |
(R)-N-((2S,5S,8S,11R,12S,15S,18S,21R)-5-Benzyl-2,8-di-sec-butyl-15-(3-guanidinopropyl)-21-methoxy-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-10-oxa-1,4,7,14,17-pentaazabicyclo[16.3.1]docosan-12-yl)-2,3-dihydroxypropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1076831; Micropeptin MZ859; BDBM50312533
Click to Show/Hide
|
||||
| Activity |
IC50 = 52900 nM
|
[27] | |||
| Compound Name |
1-{4-[4-Amino(imino)methylphenylcarbamoylmethyl]hexahydro-1-pyridinylcarbonyloxy}-5-[4-(2-hexahydro-4-pyridinylethylcarbamoyl)hexahydro-1-pyrazinylcarbonyloxy]cyclooctane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL295007; BDBM50101022
Click to Show/Hide
|
||||
| Activity |
Ki = 52900 nM
|
[28] | |||
| Compound Name |
3-[4-Carbamimidoyl-2-(2-{4-[1-(1-imino-ethyl)-piperidin-4-yloxy]-benzoylamino}-ethoxy)-phenyl]-2-oxo-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL292235; SCHEMBL5099121; BDBM50127495
Click to Show/Hide
|
||||
| Activity |
Ki = 53000 nM
|
[29] | |||
| Compound Name |
Nazumamide A
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372722; BDBM50215571; ZINC29407669
Click to Show/Hide
|
||||
| Activity |
IC50 = 53000 nM
|
[24] | |||
| Compound Name |
Acetic acid;1-[4-[(5S)-5-[[(4-carbamimidoylphenyl)methylamino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391198
Click to Show/Hide
|
||||
| Activity |
Ki = 53000 nM
|
[30] | |||
| Compound Name |
Benzyl (3aS,6aR)-6-allyl-4-(methylsulfonyl)-5-oxohexahydropyrrolo[3,2-b]pyrrole-1(2H)-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2367632; SCHEMBL6618851; BDBM50066997
Click to Show/Hide
|
||||
| Activity |
IC50 = 53170 nM
|
[1] | |||
| Compound Name |
((R)-1-{(R)-1-[(6-Carbamimidoyl-pyridin-3-ylmethyl)-carbamoyl]-ethylcarbamoyl}-2-cyclohexyl-ethylamino)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL378185; BDBM50182202
Click to Show/Hide
|
||||
| Activity |
IC50 = 53600 nM
|
[31] | |||
| Compound Name |
Chembl296315
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372731; BDBM50070762
Click to Show/Hide
|
||||
| Activity |
IC50 = 54000 nM
|
[24] | |||
| Compound Name |
Acetic acid;(2S)-1-butyl-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3423009; BDBM50082640
Click to Show/Hide
|
||||
| Activity |
Ki = 54000 nM
|
[32] | |||
| Compound Name |
Chembl296313
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372696; BDBM50070771
Click to Show/Hide
|
||||
| Activity |
IC50 = 54000 nM
|
[24] | |||
| Compound Name |
Tert-butyl N-[(2R)-2-[2-[(4-carbamimidoylphenyl)methylamino]-2-oxoethyl]-3-oxomorpholin-4-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1744054; BDBM50370260
Click to Show/Hide
|
||||
| Activity |
IC50 = 54700 nM
|
[33] | |||
| Compound Name |
2-{5-[Amino(iminio)methyl]-1H-benzimidazol-2-YL}benzenolate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CRA_1144; CHEMBL433501; AC1OARPH; SCHEMBL4315225; CTK0I8807; DTXSID70425524; ZINC6040624; BDBM50100897; DB03643; 2-(2-Hydroxyphenyl)-1H-benzimidazole-5-carboxamidine; Q27094562; 1H-Benzimidazole-5-carboximidamide, 2-(2-hydroxyphenyl)-; 2-{5-[amino(iminio)methyl]-1H-benzimidazol-2-yl}phenolate
Click to Show/Hide
|
||||
| Activity |
Ki = 55000 nM
|
[34] | |||
| Compound Name |
N-[1-(1-Amino-isoquinolin-6-ylmethyl)-2-oxo-2-piperidin-1-yl-ethyl]-2-(naphthalene-2-sulfonylamino)-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL159435; BDBM50075823; 1-[2-[N-(2-Naphthylsulfonyl)glycylamino]-3-(1-amino-6-isoquinolinyl)propionyl]piperidine
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[35] | |||
| Compound Name |
(2S)-2-[(D-Arg-Gly-)Amino]-5-guanidinopentanal
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372448; BDBM50083999; (S)-2-Amino-5-guanidino-pentanoic acid [(1-formyl-4-guanidino-butylcarbamoyl)-methyl]-amide
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[14] | |||
| Compound Name |
1-(4-Cyclohexyl-butyryl)-pyrrolidine-2-carboxylic acid (1-formyl-4-guanidino-butyl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL102849; BDBM50046349
Click to Show/Hide
|
||||
| Activity |
EC50 = 56000 nM
|
[36] | |||
| Compound Name |
4-[(E)-(5-Oxo-2-phenyl-1,3-oxazol-4-ylidene)methyl]benzenecarboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945236; BDBM50363655
Click to Show/Hide
|
||||
| Activity |
IC50 = 56100 nM
|
[37] | |||
| Compound Name |
(2S)-1-Acetyl-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL605289
Click to Show/Hide
|
||||
| Activity |
Ki = 56100 nM
|
[38] | |||
| Compound Name |
2-Methoxy-3,5-dichlorobenzenesulfonic acid 5-methyl-3-(3-hydroxyphenethyloxy)phenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL324953; BDBM50422367
Click to Show/Hide
|
||||
| Activity |
IC50 = 56234.13 nM
|
[39] | |||
| Compound Name |
5-Amino-1-[(3-carbamimidoylphenyl)methyl]-N-[(1-methylpyridin-1-ium-4-yl)methyl]indole-2-carboxamide;2,2,2-trifluoroacetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL540899
Click to Show/Hide
|
||||
| Activity |
Ki = 57000 nM
|
[40] | |||
| Compound Name |
Methyl N-[4-[2-[(2S,4R)-1-(4-carbamimidoylpiperazine-1-carbonyl)-4-(1-methylsulfonylpiperidin-4-yl)pyrrolidin-2-yl]-5-chloro-1H-imidazol-4-yl]phenyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3977040; SCHEMBL16781646; BDBM238263; US9394250, 88
Click to Show/Hide
|
||||
| Activity |
IC50 = 57000 nM
|
[41] | |||
| Compound Name |
(S)-2-{(S)-2-[(S)-2-(5-Amino-pentanoylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-phenyl-propionic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL417058; BDBM50039011
Click to Show/Hide
|
||||
| Activity |
IC50 = 57100 nM
|
[42] | |||
| Compound Name |
[4-[2-(5-Carbamimidoyl-2-hydroxybenzenesulfonylamino)-ethyl]-2'-methanesulfonoylbiphenyl-3-yloxy]acetic acid hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL463179; SCHEMBL3893143
Click to Show/Hide
|
||||
| Activity |
Ki = 57800 nM
|
[43] | |||
| Compound Name |
1-N-[(4-Carbamimidoylphenyl)methyl]-2-N-(2-phenylethyl)cyclopentene-1,2-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17781; BDBM50125836; Cyclopent-2-ene-1,2-dicarboxylic acid 1-(4-carbamimidoyl-benzylamide) 2-(phenethyl-amide)
Click to Show/Hide
|
||||
| Activity |
IC50 = 58000 nM
|
[44] | |||
| Compound Name |
2-Ketobenzothiazole 46
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL176016; BDBM14106
Click to Show/Hide
|
||||
| Activity |
IC50 = 58000 nM
|
[11] | |||
| Compound Name |
3-Methylbenzenesulfonic acid 3-[4-(aminomethyl)phenethyloxy]phenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL116392; BDBM50422372
Click to Show/Hide
|
||||
| Activity |
IC50 = 58884.37 nM
|
[39] | |||
| Compound Name |
Acetic acid;(2S)-2-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-1,2-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4081362; BDBM50259722
Click to Show/Hide
|
||||
| Activity |
Ki = 59000 nM
|
[45] | |||
| Compound Name |
[2-[1,2-Bis(2-fluorophenyl)ethyl]-1H-indol-5-yl]methanamine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL27037; BDBM50287155; C-{2-[1,2-Bis-(2-fluoro-phenyl)-ethyl]-1H-indol-5-yl}-methylamine
Click to Show/Hide
|
||||
| Activity |
IC50 = 59000 nM
|
[46] | |||
| Compound Name |
1beta,5beta-Bis[4-(4-amidinobenzylcarbamoyl)piperazinocarbonyloxy]cyclooctane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL298256; SCHEMBL7416220; BDBM50093187; 1,5-di{4-[4-amino(imino)methylbenzylcarbamoyl]hexahydro-1-pyrazinylcarbonyloxy}cyclooctane
Click to Show/Hide
|
||||
| Activity |
Ki = 59500 nM
|
[28] | |||
| Compound Name |
N-[(2R)-1-[4-(2-Hydroxyethyl)piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-3-methyl-1,2,3,4-tetrahydroquinoline-8-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40319; BDBM50090232; 1-[N-(3-Methyl-1,2,3,4-tetrahydroquinoline-8-ylsulfonyl)-D-tryptophyl]-4-(2-hydroxyethyl)piperidine
Click to Show/Hide
|
||||
| Activity |
Ki = 59900 nM
|
[47] | |||
| Compound Name |
N-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-[(S)-2-oxo-3-(2-oxo-2-piperidin-1-yl-ethyl)-4-phenylmethanesulfonyl-piperazin-1-yl]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL350280; SCHEMBL7323704; BDBM50125018
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[48] | |||
| Compound Name |
4-[(3-Carbamimidoylphenyl)sulfonylamino]-N-[(3,4-dimethoxyphenyl)methyl]butanamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159392
Click to Show/Hide
|
||||
| Activity |
Ki = 60000 nM
|
[26] | |||
| Compound Name |
6-Chloro-2-(2-hydroxy-3-phenylphenyl)-1H-indole-5-carboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339902; 6-Chloro-2-(2-Hydroxybiphenyl-3-yl)-1H-Indole-5-Carboxamidine; SCHEMBL4321170; BDBM50106240; 2-(2-Hydroxy-3-biphenylyl)-6-chloro-1H-indole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 60000 nM
|
[49] | |||
| Compound Name |
Sodium;[3-ethoxycarbonyl-2-[(3-ethoxycarbonyl-6-methoxy-2-methyl-1-benzofuran-5-yl)oxymethyl]-6-methoxy-1-benzofuran-5-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812010
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[50] | |||
| Compound Name |
2-[N-(Benzylsulfonyl)-D-Phe-L-Asn-L-Arg-]thiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL257867; BDBM50228753
Click to Show/Hide
|
||||
| Activity |
IC50 = 60000 nM
|
[51] | |||
| Compound Name |
2-Pyridin-2-yl-1H-benzimidazole-6-carboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL381148; APD-4; SCHEMBL6161244; BDBM16306; CTK0J9552; DTXSID40434567; 2-pyridin-2-yl-3H-benzimidazole-5-carboximidamide; 1H-Benzimidazole-5-carboximidamide, 2-(2-pyridinyl)-; 2-(pyridin-2-yl)-1H-1,3-benzodiazole-6-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 60000 nM
|
[52] | |||
| Compound Name |
Ethyl {(1S)-5-amino-1-[(5-{4-[(2,3-dihydro-1H-inden-2-ylamino)carbonyl]benzyl}-1,2,4-oxadiazol-3-YL)carbonyl]pentyl}carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL214368; CRA23; BDBM14312; Q27458643
Click to Show/Hide
|
||||
| Activity |
Ki = 60000 nM
|
[53] | |||
| Compound Name |
Methyl 3-[4-[(6-methoxynaphthalene-2-carbonyl)amino]phenyl]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945764; BDBM50363660
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62000 nM
|
[4] | |||
| Compound Name |
6-Carbamimidoyl-naphthalene-2-carboxylic acid (3,5-dimethoxy-phenyl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL112995; SCHEMBL7340926; BDBM50138678
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62000 nM
|
[4] | |||
| Compound Name |
6-Methoxy-N-[4-(3-methoxyphenyl)phenyl]naphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945765; BDBM50363661
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62000 nM
|
[4] | |||
| Compound Name |
Benzyl N-[2-(4-aminophenyl)-1-diphenoxyphosphorylethyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL2249441; CHEMBL3771195
Click to Show/Hide
|
||||
| Activity |
IC50 = 62000 nM
|
[54] | |||
| Compound Name |
2-N-[4-[3-(Trifluoromethyl)phenyl]phenyl]naphthalene-2,6-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945757; BDBM50363658
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62000 nM
|
[4] | |||
| Compound Name |
4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
AEBSF HCl; AEBSF hydrochloride; AEBSF; Pefabloc SC; AEBSF (hydrochloride); AEBSF, Hydrochloride; MFCD00132962; 4-(2-Aminoethyl)benzene-1-sulfonyl fluoride hydrochloride; 4-(2-Aminoethyl)benzenesulphonyl fluoride hydrochloride; Benzenesulfonyl fluoride, 4-(2-aminoethyl)-, hydrochloride; AEBSF.HCl; 4-(2-Aminoethyl)benzenesulfonylfluoride hydrochloride; 30827-99-7 (HCl); Benzenesulfonyl fluoride, 4-(2-aminoethyl)-, hydrochloride (1:1); AEBSF hydrochloride, 98%; 4-(2-aminoethyl)benzenesulfonyl fluoride;hydrochloride; 4-(2-aminoethyl) benzenesulfonyl fluoride hydrochloride; Benzenesulfonylfluoride, 4-(2-aminoethyl)-, hydrochloride (1:1); CHEMBL1256178; SR-01000075690; AEBSF-hydrochloride; PubChem14462; EU-0100132; ACMC-1CTY2; 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl; SCHEMBL25973; MLS002153464; AEBSF HCl Biochemistry grade; CTK1C4244; KS-00000VYT; DTXSID60184830; BCP32155; EX-A2487; Tox21_500132; ANW-43152; NSC727364; PC5642; Pefabloc(R) SC, analytical standard; s7378; SBB003219; AKOS015847774; CCG-207883; FS-5456; LP00132; NSC-727364; VZ27664; NCGC00093623-01; NCGC00260817-01; AK-82709; HY-12821; QC-10428; SMR001230821; SY007034; 4-(2-Aminoethyl)benzenesulfonylfluoride HCl; AB0014776; DB-047913; 2-AMINOETHYLPHENYLSULFONEHYDROCHLORIDE; FT-0616512; SW219355-1; 4-(2-Aminoethyl)Benzenesulfonyl Fluoride HCl; AEBSF Ready Made Solution, 100 mM in water; 4-(2-Aminoethyl)benzenesulfonyl fluoride, HCl; A 8456; A14270; K-7365; M01245; P-1195; [4-(2-aminoethyl)phenyl]fluorosulfone, chloride; Pefabloc, Antibiotic for Culture Media Use Only; 827A997; 4-(2-Aminoethyl)benzenesulfonylfluoridehydrochloride; SR-01000075690-1; 4-(2-aminoethyl)-benzenesulfonylfluoride hydrochloride; 4-(2-aminoethyl)benzenesulfonyl fluoride,hydrochloride; Benzenesulfonyl fluoride, p-(2-aminoethyl)-, hydrochloride; Pefabloc(R) SC, certified reference material, TraceCERT(R); 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride, >=97%
Click to Show/Hide
|
||||
| Activity |
IC50 = 62000 nM
|
[55] | |||
| Compound Name |
2-N-[4-(3-Methoxyphenyl)phenyl]naphthalene-2,6-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945756; BDBM50363657
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62000 nM
|
[4] | |||
| Compound Name |
Methyl 3-[4-[(6-methoxynaphthalen-2-yl)sulfonylamino]phenyl]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945918; BDBM50363664
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62000 nM
|
[4] | |||
| Compound Name |
6-Methoxy-N-[4-[3-(trifluoromethyl)phenyl]phenyl]naphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945767; BDBM50363663
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62000 nM
|
[4] | |||
| Compound Name |
6-[N-(4-(Aminomethyl)phenyl)carbamyl]-2-naphthalenecarboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL324168; 6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-2-NAPHTHAMIDE; uPa_9; N-[4-(aminomethyl)phenyl]-6-carbamimidoylnaphthalene-2-carboxamide; SCHEMBL4330440; ZINC2047485; BDBM50138662; DB02398; Q27093399; N-(4-(aminomethyl)phenyl)-6-carbamimidoyl-2-naphthamide; N-[4-(Aminomethyl)phenyl]-6-amidino-2-naphthalenecarboxamide; 6-Carbamimidoyl-naphthalene-2-carboxylic acid (4-aminomethyl-phenyl)-amide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62000 nM
|
[4] | |||
| Compound Name |
6-Methoxy-N-[4-(3-nitrophenyl)phenyl]naphthalene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945766; BDBM50363662
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 62000 nM
|
[4] | |||
| Compound Name |
(3R,6R,8As)-6-amino-N-[4-(diaminomethylideneamino)butyl]-5-oxo-2,3,6,7,8,8a-hexahydro-[1,3]thiazolo[3,2-a]pyridine-3-carboxamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL332426
Click to Show/Hide
|
||||
| Activity |
Ki = 62400 nM
|
[56] | |||
| Compound Name |
(E)-2-(3-Nitrophenyl)-N-[3-[[1-(pyridin-3-ylmethyl)triazol-4-yl]methoxy]phenyl]ethenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1824542; BDBM50352507
Click to Show/Hide
|
||||
| Activity |
Ki = 62500 nM
|
[57] | |||
| Compound Name |
N-[4-(Benzimidazol-1-yl)phenyl]-2-(5-carbamimidoyl-1-benzothiophen-3-yl)-3-phenylpropanamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL183384
Click to Show/Hide
|
||||
| Activity |
Ki ~ 63000 nM
|
[58] | |||
| Compound Name |
Tert-butyl 4-[3-[(3-carbamimidoylphenyl)sulfonylamino]propanoylamino]benzoate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159291
Click to Show/Hide
|
||||
| Activity |
Ki = 63000 nM
|
[26] | |||
| Compound Name |
Acetic acid;(2S)-N-[(4-carbamimidoylphenyl)methyl]-1-propylpyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3423008; BDBM50082641
Click to Show/Hide
|
||||
| Activity |
Ki = 63000 nM
|
[32] | |||
| Compound Name |
2-Ketobenzothiazole 47
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL176221; BDBM14107
Click to Show/Hide
|
||||
| Activity |
IC50 = 63000 nM
|
[11] | |||
| Compound Name |
(2S)-5-(Diaminomethylideneamino)-N-[2-[[5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]-2-(2-phenylethylsulfonylamino)pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40380; BDBM50083983
Click to Show/Hide
|
||||
| Activity |
IC50 = 64000 nM
|
[14] | |||
| Compound Name |
Tert-butyl 3-[[2-[(4-carbamimidoylphenyl)sulfonylamino]acetyl]amino]benzoate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159284
Click to Show/Hide
|
||||
| Activity |
Ki = 64000 nM
|
[26] | |||
| Compound Name |
(S)-Ethyl 1-(5-(4-phenethoxybenzyl)-1,2,4-oxadiazol-3-yl)-6-amino-1-oxohexan-2-ylcarbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL211561; BDBM50187800
Click to Show/Hide
|
||||
| Activity |
Ki = 64000 nM
|
[59] | |||
| Compound Name |
4-Chloro-2-(2-hydroxy-3-biphenylyl)-1H-indole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL125153; BDBM50106238; 4-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 65000 nM
|
[49] | |||
| Compound Name |
2-(2-Chlorophenyl)-4-[5-(2,6-dimethylpiperidino)pentyl]-2H-1,4-benzoxazine-3(4H)-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL423149; SCHEMBL7123883; BDBM50093304; 2-(2-chlorophenyl)-4-[5-(2,6-dimethylpiperidin-1-yl)pentyl]-1,4-benzoxazin-3-one; 2-(2-Chloro-phenyl)-4-[5-(2,6-dimethyl-piperidin-1-yl)-pentyl]-4H-benzo[1,4]oxazin-3-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 65000 nM
|
[60] | |||
| Compound Name |
2-(5-Methyl-2-hydroxyphenyl)-1H-benzimidazole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL433179; BDBM50102793; ZINC13863688; 2-(2-Hydroxy-5-methyl-phenyl)-1H-benzoimidazole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 65000 nM
|
[61] | |||
| Compound Name |
[2-[2-[3,5-Dicyano-6-nitro-4-(4-phenylmethoxyphenyl)pyridin-2-yl]sulfanylacetyl]-6-sulfooxyphenyl] hydrogen sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3350703
Click to Show/Hide
|
||||
| Activity |
IC50 = 65900 nM
|
[62] | |||
| Compound Name |
3-Methyl-2-phenyl-1H-indole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL26896; BDBM50287158
Click to Show/Hide
|
||||
| Activity |
IC50 = 66000 nM
|
[46] | |||
| Compound Name |
4-[4-[(4-Carbamimidoylphenyl)sulfonylamino]butanoylamino]benzoic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159299
Click to Show/Hide
|
||||
| Activity |
Ki = 66000 nM
|
[26] | |||
| Compound Name |
Diphenyl 1-[(N-p-methylbenzoyl-D-seryl)-L-alanyl]amino-2-(4-guanidinophenyl)ethanephosphonate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL404226; BDBM50194740
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[63] | |||
| Compound Name |
4-[4-[1-[2-(5-Chlorothiophen-2-yl)acetyl]-6-methoxy-4-oxo-2H-quinazolin-3-yl]phenyl]morpholin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4090253; BDBM50259113
Click to Show/Hide
|
||||
| Activity |
IC50 = 67000 nM
|
[64] | |||
| Compound Name |
(3E,9R,12S)-19-Chloro-9-cyclohexyl-12-(2-methylpropyl)-7,7-dioxo-7lambda6-thia-8,11,14,23-tetrazatricyclo[14.7.0.017,22]tricosa-1(16),3,17(22),18,20-pentaene-10,13-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1289860; BDBM50331668
Click to Show/Hide
|
||||
| Activity |
IC50 = 67900 nM
|
[65] | |||
| Compound Name |
Acetic acid;(2S)-1-acetyl-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4091457
Click to Show/Hide
|
||||
| Activity |
Ki = 68000 nM
|
[45] | |||
| Compound Name |
N,N-(4-Xylylidene)bisaminoguanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL534939; N,N'-(p-xylylidene)bis(aminoguanidine); BRN 2622762; VI 58977; biguanidine, 1; Hydrazinecarboximidamide, 2,2'-(1,4-phenylenedimethylidyne)bis-; CHEMBL403278; Guanidine, 1,1'-(p-phenylenebis(methylidynenitrilo))di-; SCHEMBL10054978; BDBM33261; BDBM50410811; CCG-44111; ZINC42988810; SN-20440; AJ-264/34032018; SR-01000633972-1
Click to Show/Hide
|
||||
| Activity |
Ki = 68000 nM
|
[66] | |||
| Compound Name |
Chembl44548
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372703; BDBM50070724
Click to Show/Hide
|
||||
| Activity |
IC50 = 68000 nM
|
[24] | |||
| Compound Name |
Acetic acid;(2S)-N-[(4-carbamimidoylphenyl)methyl]-1-methylsulfonylpyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4062139; BDBM50259725
Click to Show/Hide
|
||||
| Activity |
Ki = 68000 nM
|
[45] | |||
| Compound Name |
N-[4-[1-[[2-[(4-Carbamimidoylphenyl)carbamoylamino]acetyl]amino]ethyl]phenyl]piperidine-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339880; SCHEMBL4420164; BDBM50148947
Click to Show/Hide
|
||||
| Activity |
Ki = 68500 nM
|
[15] | |||
| Compound Name |
Chembl296667
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372664; BDBM50070764
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[24] | |||
| Compound Name |
(1-{[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-carbamoyl}-2-hydroxy-ethyl)-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL350657; BDBM50110013; Boc-L-Ser-Gly-(4-Amidinobenzyl)NH2
Click to Show/Hide
|
||||
| Activity |
Ki = 69000 nM
|
[67] | |||
| Compound Name |
2-[6-(3-Carbamimidoylphenoxy)-4-[di(propan-2-yl)amino]-3,5-difluoropyridin-2-yl]oxy-5-[(3-methoxyphenyl)methylcarbamoyl]benzoic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL204084
Click to Show/Hide
|
||||
| Activity |
IC50 = 69000 nM
|
[68] | |||
| Compound Name |
1-[4-[(5S)-5-[[(5-Chlorothiophene-2-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]-2-oxopiperidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3134465
Click to Show/Hide
|
||||
| Activity |
Ki = 69600 nM
|
[69] | |||
| Compound Name |
[(1S)-2-(4-Methoxyphenyl)-1-[[(2R)-3-naphthalen-2-yl-2-(phenylmethoxycarbonylamino)propanoyl]amino]ethyl]-phenylphosphinic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1160263
Click to Show/Hide
|
||||
| Activity |
IC50 = 70000 nM
|
[70] | |||
| Compound Name |
2-(2-Hydroxy-biphenyl-3-yl)-3-methyl-3H-benzoimidazole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL96428; BDBM50102769
Click to Show/Hide
|
||||
| Activity |
Ki = 70000 nM
|
[61] | |||
| Compound Name |
6-Fluoro-2-[2-hydroxy-3-(pyrrolidin-2-ylmethoxy)-phenyl]-1H-benzoimidazole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL62397; BDBM50115859
Click to Show/Hide
|
||||
| Activity |
Ki = 70000 nM
|
[9] | |||
| Compound Name |
3-[(4-Methoxyphenyl)sulfamoyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159374
Click to Show/Hide
|
||||
| Activity |
Ki = 71000 nM
|
[26] | |||
| Compound Name |
[2'-Hydroxy-3'-(1H-pyrrolo[3,2-c]pyridin-2-yl)-biphenyl-3-ylmethyl]-urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-azaindole analog 2; CHEMBL209022; BDBM14864; {[3-(2-hydroxy-3-{1H-pyrrolo[3,2-c]pyridin-2-yl}phenyl)phenyl]methyl}urea; DB07247; Q27096472; 1-{[2'-hydroxy-3'-(1H-pyrrolo[3,2-c]pyridin-2-yl)biphenyl-3-yl]methyl}urea
Click to Show/Hide
|
||||
| Activity |
Ki = 71500 nM
|
[71] | |||
| Compound Name |
(S)-3-Amino-N-(3-(N-(3-(3-carbamimidoylphenyl)-1-oxo-1-(piperazin-1-yl)propan-2-yl)sulfamoyl)phenyl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL493118; SCHEMBL12998731; BDBM50257664; US8569313, 54
Click to Show/Hide
|
||||
| Activity |
Ki = 71700 nM
|
[72] | |||
| Compound Name |
3-[[6-[(3-Carbamimidoylphenoxy)methyl]naphthalen-2-yl]methoxy]benzenecarboximidamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3277930; BDBM50016533
Click to Show/Hide
|
||||
| Activity |
IC50 = 72000 nM
|
[73] | |||
| Compound Name |
(S)-N-(3-Chlorobenzyl)-1-(2-cyclopentylacetyl)pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL598417; BDBM50307843
Click to Show/Hide
|
||||
| Activity |
Ki = 72400 nM
|
[38] | |||
| Compound Name |
N-(3-Guanidino-3-oxo-propyl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-azepan-1-yl)-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL333098; BDBM50073324
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[74] | |||
| Compound Name |
(2S)-1-[(2S,3As,7aS)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carbonyl]-N-[(2R)-1-[[(2S)-1-amino-3-(4-methylphenyl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927664; BDBM50359565
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[75] | |||
| Compound Name |
((R)-2-Cyclohexyl-1-{cyclopentyl-[(2-piperidin-4-yl-ethylcarbamoyl)-methyl]-carbamoyl}-ethylamino)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339878; BDBM50073310
Click to Show/Hide
|
||||
| Activity |
IC50 = 74000 nM
|
[74] | |||
| Compound Name |
6-Hydroxy-2-(2-hydroxy-3-biphenylyl)-1H-indole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127407; BDBM50106242; 6-Hydroxy-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki ~ 75000 nM
|
[49] | |||
| Compound Name |
6-Methoxy-2-(2-hydroxy-3-biphenylyl)-1H-indole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL126707; BDBM50106241; 2-(2-Hydroxy-biphenyl-3-yl)-6-methoxy-1H-indole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki ~ 75000 nM
|
[49] | |||
| Compound Name |
2-(2-Hydroxy-3-ethoxyphenyl)-6-chloro-1H-benzimidazole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL62378; BDBM50115862; 6-Chloro-2-(3-ethoxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki ~ 75000 nM
|
[9] | |||
| Compound Name |
6-Methyl-2-(2-hydroxy-3-biphenylyl)-1H-indole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127278; BDBM50106243; 2-(2-Hydroxy-biphenyl-3-yl)-6-methyl-1H-indole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki ~ 75000 nM
|
[49] | |||
| Compound Name |
2-(2-Hydroxy-3-ethoxyphenyl)-6-fluoro-1H-benzimidazole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL62753; BDBM50115853; 2-(3-Ethoxy-2-hydroxy-phenyl)-6-fluoro-1H-benzoimidazole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki ~ 75000 nM
|
[9] | |||
| Compound Name |
Cyanin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Cyanidin 3,5-di-O-glucoside; Cyanidin 3,5-O-diglucoside; Cyanidin-3,5-O-diglucoside; Cyanidin-3, 5-di-O-glucoside; UNII-2U0001Z916; 2U0001Z916; Cyanidin 3,5-diglucoside; 3,5-bis(beta-D-glucopyranosyloxy)-3',4',7-trihydroxyflavylium; Cyanidin-3,5-di-O-glucoside; Cyanidin 3,5-diglucoside ion; SCHEMBL6138846; CHEMBL2425137; Cyanidin 3,5-diglucoside cation; DTXSID70331611; Cyanidin 3,5-beta-D-o-diglucoside; BDBM50005093; Cyanidin 3-O-glucoside-5-O-glucoside; C08639; Q21099632; Flavylium, 3,5-bis(beta-D-glucopyranosyloxy)-3',4',7-trihydroxy-
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[2] | |||
| Compound Name |
(2R)-5-(Diaminomethylideneamino)-N-[2-[[(2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]-2-(3-phenylpropanoylamino)pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372441; BDBM50084009
Click to Show/Hide
|
||||
| Activity |
IC50 = 75000 nM
|
[14] | |||
| Compound Name |
3-[4-[(3-Carbamimidoylphenyl)sulfonylamino]butanoylamino]benzoic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159361
Click to Show/Hide
|
||||
| Activity |
Ki = 75000 nM
|
[26] | |||
| Compound Name |
(2S)-1-[(2R)-2-Amino-2-cyclohexylethyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3423000; BDBM50082523
Click to Show/Hide
|
||||
| Activity |
Ki = 76000 nM
|
[32] | |||
| Compound Name |
{2-[2-(1-Formyl-4-guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-1-phenyl-ethyl}-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL320407; BDBM50046369
Click to Show/Hide
|
||||
| Activity |
IC50 = 78000 nM
|
[76] | |||
| Compound Name |
3-[3-(3-Benzyl-5-carbamoyl-1H-indol-2-yl)-5-bromo-4-hydroxy-phenyl]-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL433079; BDBM50101888
Click to Show/Hide
|
||||
| Activity |
Ki = 78000 nM
|
[77] | |||
| Compound Name |
((R)-1-{[(1-Formyl-4-guanidino-butylcarbamoyl)-methyl]-carbamoyl}-4-guanidino-butyl)-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372455; BDBM50083993; (2S)-2-[(Boc-L-Arg-Gly-)Amino]-5-guanidinopentanal
Click to Show/Hide
|
||||
| Activity |
IC50 = 79000 nM
|
[14] | |||
| Compound Name |
CID 309369
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3247193; ZINC1749234; BDBM50010258; AKOS012235388
Click to Show/Hide
|
||||
| Activity |
Ki = 79432.82 nM
|
[78] | |||
| Compound Name |
2-(1-Hydroxy-2-naphthyl)-1H-benzimidazole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL319997; BDBM50102783; ZINC12354857; 2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 80000 nM
|
[61] | |||
| Compound Name |
2-(3-Methoxy-2-hydroxyphenyl)-1H-benzimidazole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL94139; SCHEMBL6289996; BDBM50102788; 2-(2-Hydroxy-3-methoxy-phenyl)-1H-benzoimidazole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 80000 nM
|
[61] | |||
| Compound Name |
4-[[5-[(4-Carbamimidoylphenyl)methoxy]naphthalen-1-yl]oxymethyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3277926; BDBM50016529
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[73] | |||
| Compound Name |
(S)-2-{(S)-2-[(S)-2-(6-Amino-hexanoylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-phenyl-propionic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL68124; BDBM50039014
Click to Show/Hide
|
||||
| Activity |
IC50 = 80000 nM
|
[42] | |||
| Compound Name |
Propan-2-yl N-[(2R)-2-[2-[(4-carbamimidoylphenyl)methylamino]-2-oxoethyl]-3-oxomorpholin-4-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1744051; BDBM50370266
Click to Show/Hide
|
||||
| Activity |
IC50 = 80600 nM
|
[33] | |||
| Compound Name |
4-[4-[1-[2-(4-Chlorophenyl)acetyl]-6-methoxy-4-oxo-2H-quinazolin-3-yl]phenyl]morpholin-3-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4076970; BDBM50259086
Click to Show/Hide
|
||||
| Activity |
IC50 = 81000 nM
|
[64] | |||
| Compound Name |
Chembl263934
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372705; BDBM50070734
Click to Show/Hide
|
||||
| Activity |
IC50 = 82000 nM
|
[24] | |||
| Compound Name |
2-Ketobenzothiazole 23
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL340547; CHEMBL360684; SCHEMBL18866677; BDBM14083; BDBM50131979; Cyclopentanecarboxylic acid [1-(benzothiazole-2-carbonyl)-4-guanidino-butyl]-amide; TFA; N-[1-(1,3-benzothiazol-2-yl)-5-carbamimidamido-1-oxopentan-2-yl]cyclopentanecarboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 = 82000 nM
|
[11] | |||
| Compound Name |
1,3-Di{4-[5-amino(imino)methylbenzo[b]furan-2-ylcarbonyl]hexahydro-1-pyrazinyl}-1,3-propanedione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL110645; BDBM50083553; 2,2'-[1,3-Dioxopropane-1,3-diylbis(piperazine-4,1-diylcarbonyl)]bis(benzofuran-5-carboxamidine)
Click to Show/Hide
|
||||
| Activity |
Ki = 82000 nM
|
[25] | |||
| Compound Name |
4-[[3-(1-Benzylpiperidin-4-yl)-5-methyl-2-oxo-1,3-diazinan-1-yl]methyl]benzenecarboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3780039; BDBM50158164
Click to Show/Hide
|
||||
| Activity |
Ki = 82200 nM
|
[79] | |||
| Compound Name |
(2R)-N-[(2S)-1-[(4-Carbamimidoylphenyl)methylamino]-4-methylsulfanyl-1-oxobutan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL498640; BDBM50272579
Click to Show/Hide
|
||||
| Activity |
IC50 = 83000 nM
|
[80] | |||
| Compound Name |
4-[(3-Carbamimidoylphenyl)sulfonylamino]-N-(3,4-dimethoxyphenyl)butanamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159390
Click to Show/Hide
|
||||
| Activity |
Ki = 83000 nM
|
[26] | |||
| Compound Name |
1-N-[(2R)-5-(Diaminomethylideneamino)-1-oxopentan-2-yl]-2-N-methyl-2-N-(2-phenylethyl)cyclohexane-1,2-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL281784; BDBM50070304
Click to Show/Hide
|
||||
| Activity |
IC50 = 84000 nM
|
[81] | |||
| Compound Name |
Methyl N-[4-[2-[(2S,4S)-1-(4-carbamimidoylcyclohexanecarbonyl)-4-(4-methylsulfonylpiperazin-1-yl)pyrrolidin-2-yl]-5-chloro-1H-imidazol-4-yl]phenyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3961710; BDBM238267; US9394250, 99
Click to Show/Hide
|
||||
| Activity |
IC50 = 84000 nM
|
[41] | |||
| Compound Name |
(R)-N-[(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-2-(3-trifluoromethyl-phenyl)-ethyl]-3-phenyl-2-phenylmethanesulfonylamino-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL309394; BDBM50130065; 2-[N-(Benzylsulfonyl)-D-Phe-3-(trifluoromethyl)-L-Phe-L-Arg-]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 84900 nM
|
[7] | |||
| Compound Name |
1,7-Di{4-[5-amino(imino)methylbenzo[b]furan-2-ylcarbonyl]hexahydro-1-pyrazinyl}-1,7-heptanedione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL326443; BDBM50083545; 2,2'-[1,7-Dioxoheptane-1,7-diylbis(piperazine-4,1-diylcarbonyl)]bis(benzofuran-5-carboxamidine)
Click to Show/Hide
|
||||
| Activity |
Ki = 85000 nM
|
[25] | |||
| Compound Name |
{(R)-1-[2-(4-Carbamimidoyl-benzylcarbamoyl)-indan-2-ylcarbamoyl]-3-methyl-pentylamino}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL215556; BDBM50193228
Click to Show/Hide
|
||||
| Activity |
IC50 = 85000 nM
|
[82] | |||
| Compound Name |
Tert-butyl 4-[[2-[(4-carbamimidoylphenyl)sulfonylamino]acetyl]amino]benzoate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159283
Click to Show/Hide
|
||||
| Activity |
Ki = 85000 nM
|
[26] | |||
| Compound Name |
2-[(3R)-3-Amino-4-oxo-2,3-dihydro-1,5-benzothiazepin-5-yl]-N-[(4-carbamimidoylphenyl)methyl]acetamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL557472
Click to Show/Hide
|
||||
| Activity |
IC50 = 87000 nM
|
[83] | |||
| Compound Name |
N-[(6-Amino-2-methylpyridin-3-yl)methyl]-2-[(3S)-3-amino-4-oxo-2,3-dihydro-1,5-benzothiazepin-5-yl]acetamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL564165
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[83] | |||
| Compound Name |
N-[2-[(6-Aminopyridin-3-yl)methylamino]-2-oxoethyl]-2-(benzylsulfonylamino)-4-(1-oxidopyridin-1-ium-2-yl)butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL230879; BDBM50211561
Click to Show/Hide
|
||||
| Activity |
Ki = 88000 nM
|
[84] | |||
| Compound Name |
((S)-4-Acetimidoylamino-1-{[(1-formyl-4-guanidino-butylcarbamoyl)-methyl]-carbamoyl}-butyl)-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372431; BDBM50083985
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[14] | |||
| Compound Name |
3-[3-[(3-Carbamimidoylphenyl)sulfonylamino]propanoylamino]benzoic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159304
Click to Show/Hide
|
||||
| Activity |
Ki = 88000 nM
|
[26] | |||
| Compound Name |
2,2'-(1,2-Phenylene)bis[oxy(1-oxoethane-2,1-diyl)(piperazine-4,1-diyl)carbonyl]bis(benzofuran-5-carboxamidine)
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL111643; BDBM50083549
Click to Show/Hide
|
||||
| Activity |
Ki = 88000 nM
|
[25] | |||
| Compound Name |
N-[(6-Amino-2-methylpyridin-3-yl)methyl]-2-[(3R)-3-amino-4-oxo-2,3-dihydro-1,5-benzothiazepin-5-yl]acetamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL558275
Click to Show/Hide
|
||||
| Activity |
IC50 = 88000 nM
|
[83] | |||
| Compound Name |
Tame
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Ts-Arg-OMe; Methyl P-toluenesulfonyl-L-argininate; tosyl-arginine methyl ester; UNII-1H7BKF44U1; p-toluenesulfonyl-L-arginine methyl ester; tosyl-L-arginine methyl ester; CHEMBL44752; 1H7BKF44U1; methyl N(2)-(p-tosyl)-L-argininate; p-toluensulfonyl-L-arginine methyl ester; N(alpha)-p-tosyl-L-arginine methyl ester; (S)-methyl 5-guanidino-2-(4-methylphenylsulfonamido)pentanoate; methyl N(2)-(p-toluenenesulfonyl)-L-argininate; methyl N(2)-[(p-tolyl)sulphonyl]-L-argininate; N(2)-(p-tolylsulfonyl)-L-arginine methyl ester; methyl N(2)-[(4-methylphenyl)sulfonyl]-L-argininate; TOSYLARGININE METHYL ESTER; TAME/; SCHEMBL324561; p-tosyl-l-arginine methyl ester; Nalpha-tosylarginine methyl ester; BCPP000052; ZINC1639578; ABP000326; BDBM50070707; s2225; AKOS030214485; CCG-264948; CS-0466; alpha-N-p-Tosyl-L-arginine methyl ester; NCGC00346615-01; HY-13255; SW219688-1; X7573; N-alpha-Toluenesulfonyl-L-arginine methyl ester; W-5260; AB01566842_01; p-TOLUENESULFONYL-L-ARGININE METHYL ESTER HCl; Q27131658; L-Arginine, N2-((4-methylphenyl)sulfonyl)-, methyl ester; (S)-5-Guanidino-2-(toluene-4-sulfonylamino)-pentanoic acid methyl ester
Click to Show/Hide
|
||||
| Activity |
IC50 = 89000 nM
|
[24] | |||
| Compound Name |
Sodium;[3-ethoxycarbonyl-2-[(3-ethoxycarbonyl-5-methoxy-2-methyl-1-benzofuran-6-yl)oxymethyl]-6-methoxy-1-benzofuran-5-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812021
Click to Show/Hide
|
||||
| Activity |
IC50 = 89000 nM
|
[50] | |||
| Compound Name |
2-(4-Diethylamino-2-hydroxy-phenyl)-1H-benzoimidazole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL330460; BDBM50102781; 2-[4-(Diethylamino)-2-hydroxyphenyl]-1H-benzimidazole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 90000 nM
|
[61] | |||
| Compound Name |
({3-[3-(5-Carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2-hydroxyphenyl]-4-hydroxyphenyl}methyl)urea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL378916; 5-amidinobenzimidazole analog 1; SCHEMBL12111058; BDBM14863
Click to Show/Hide
|
||||
| Activity |
Ki = 90000 nM
|
[85] | |||
| Compound Name |
Pyridin-4-yl-{2-[3-(toluene-4-sulfonylamino)-phenoxy]-ethyl}-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL24713; BDBM50126695
Click to Show/Hide
|
||||
| Activity |
Ki = 90000 nM
|
[86] | |||
| Compound Name |
2-{5-[Amino(iminio)methyl]-6-chloro-1H-benzimidazol-2-YL}-6-isobutoxybenzenolate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL62492; CRA_10972; BDBM14154; APC-10972; BDBM50115858; DB02989; Q27456966; 2-[2-Hydroxy-3-(isobutyloxy)phenyl]-6-chloro-1H-benzimidazole-5-carboxamidine; 6-Chloro-2-(2-hydroxy-3-isobutoxy-phenyl)-1H-benzoimidazole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 90000 nM
|
[9] | |||
| Compound Name |
N-[(5-Amino-1-dihydroxyboranyl-pentylcarbamoyl)-methyl]-3-phenyl-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL329258; BDBM50288415
Click to Show/Hide
|
||||
| Activity |
IC50 = 90000 nM
|
[87] | |||
| Compound Name |
(2S,3S)-N-[(1R)-1-[[3-(Butylamino)-3-oxopropyl]-diphenylsilyl]-3-methylbutyl]-3-methyl-2-[(2-naphthalen-2-ylacetyl)amino]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2182018; BDBM50398079
Click to Show/Hide
|
||||
| Activity |
IC50 = 92000 nM
|
[55] | |||
| Compound Name |
(S)-N-(3-Chlorobenzyl)-1-(3-cyclopentylpropanoyl)pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL608429; BDBM50307845
Click to Show/Hide
|
||||
| Activity |
Ki = 92900 nM
|
[38] | |||
| Compound Name |
2-N-[(4-Carbamimidoylphenyl)methyl]-1-N-ethyl-1-N-(2-fluorophenyl)cyclopent-2-ene-1,2-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17712; BDBM50125834
Click to Show/Hide
|
||||
| Activity |
IC50 = 93000 nM
|
[44] | |||
| Compound Name |
Methyl N-[4-[2-[(2S,4R)-1-(1-carbamimidoylpiperidine-4-carbonyl)-4-(1-methylsulfonylpiperidin-4-yl)pyrrolidin-2-yl]-5-chloro-1H-imidazol-4-yl]phenyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3964787; SCHEMBL16781420; BDBM238259; SB18995; US9394250, 71
Click to Show/Hide
|
||||
| Activity |
IC50 = 94000 nM
|
[41] | |||
| Compound Name |
(S)-N-(3-Chlorobenzyl)-1-(3-phenylpropanoyl)pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL597594; BDBM50307847; N-(3-Chlorobenzyl)-1-(3-phenylpropionyl)-L-prolinamide
Click to Show/Hide
|
||||
| Activity |
Ki = 94300 nM
|
[38] | |||
| Compound Name |
1beta-[[4-(4-Amidinophenylacetyl)piperazino]carbonyloxy]-5beta-[4-[2-(4-piperidinyl)ethylcarbamoyl]piperazinocarbonyloxy]cyclooctane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL38054; BDBM50101017
Click to Show/Hide
|
||||
| Activity |
Ki = 94400 nM
|
[28] | |||
| Compound Name |
4-Aminobenzamidine dihydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
p-Aminobenzamidine dihydrochloride; 4-aminobenzimidamide dihydrochloride; 4-Amidinoaniline Dihydrochloride; 4-Aminobenzenecarboximidamide dihydrochloride; Benzenecarboximidamide, 4-amino-, dihydrochloride; 4-AMINOBENZAMIDINE 2HCL; UNII-3C7VNU62AG; MFCD00013001; 3C7VNU62AG; 4-aminobenzenecarboximidamide;dihydrochloride; Benzenecarboximidamide, 4-amino-, hydrochloride (1:2); 4-Aminobenzamidine dihydrochloride, 97%; 4-AMINOBENZAMIDINE HCL SALT; Benzamidine, p-amino-, dihydrochloride; EINECS 219-692-2; ST50825558; 4-aminobenzenecarboxamidine, chloride, chloride; 4-Aminobenzamidinedihydrochloride; ACMC-209ggc; 4-Aminobenzamidine DiHCl; 4-aminobenzamidine di-hcl; KSC204E4D; SCHEMBL236095; CHEMBL1562872; CTK1A4241; DTXSID10179695; ACT00225; BCP12270; KS-000009WH; Tox21_500070; ANW-25594; SBB063615; AKOS008901225; AB01119; AS01988; CCG-221374; CS-W019509; GS-3168; H98A502; LP00070; VZ28291; 4-Aminobenzamidine dihydrochloride, 98%; NCGC00093580-01; NCGC00260755-01; AC-29284; AK-34349; BP-13026; BR-34349; SY017964; 4-aminobenzenecarboximidamide,dihydrochloride; AB0011024; EU-0100070; FT-0617552; A 7148; C-1048; C11628; 4-aminobenzene-1-carboximidamide dihydrochloride; SR-01000075172; SR-01000075172-1; Q27108667
Click to Show/Hide
|
||||
| Activity |
Ki = 95000 nM
|
[88] | |||
| Compound Name |
N-((S)-1-{[(1-Formyl-4-guanidino-butylcarbamoyl)-methyl]-carbamoyl}-4-guanidino-butyl)-oxalamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372514; BDBM50084006
Click to Show/Hide
|
||||
| Activity |
IC50 = 95000 nM
|
[14] | |||
| Compound Name |
(S)-3-(4-Aminomethyl-phenyl)-N-benzyl-2-(naphthalene-2-sulfonylamino)-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL349653; BDBM50069050
Click to Show/Hide
|
||||
| Activity |
Ki = 97200 nM
|
[89] | |||
| Compound Name |
(2S)-1-[(2S,3As,7aS)-1-[(2R)-5-(diaminomethylideneamino)-2-methylpentanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carbonyl]-N-[(2R)-1-[[(2S)-1-amino-3-(4-methylphenyl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927662; BDBM50359567
Click to Show/Hide
|
||||
| Activity |
IC50 = 98000 nM
|
[75] | |||
| Compound Name |
5-Amino-N,1-bis[(3-carbamimidoylphenyl)methyl]indole-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL328307; BDBM13865; 3-amidinobenzylindole carboxamide 49; N,1-Bis(3-amidinobenzyl)-5-amino-1H-indole-2-carboxamide; 5-amino-N,1-bis[(3-carbamimidoylphenyl)methyl]-1H-indole-2-carboxamide
Click to Show/Hide
|
||||
| Activity |
Ki = 99000 nM
|
[40] | |||
| Compound Name |
(2S)-N-[[3-[3-(4-Amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-2-hydroxyphenyl]phenyl]methyl]-2-hydroxy-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL212401; BDBM50189937
Click to Show/Hide
|
||||
| Activity |
Ki = 99000 nM
|
[85] | |||
| Compound Name |
Ethyl 1-[4-[(5S)-5-[[(2-amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]-2-oxopiperidine-4-carboxylate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391185
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
1-[4-[(5S)-5-[[[4-Chloro-3-(5-oxo-4H-1,2,4-oxadiazol-3-yl)benzoyl]amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391203; BDBM50435607
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-{4-[(S)-1-(1-imino-ethyl)-pyrrolidin-3-yloxy]-phenyl}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL439982; BDBM50068499
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
(2S)-(3'-Amidino-3-biphenyl)-5-(4-pyridylamino)pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL105532; BDBM50084676; Q27454876; (2S)-(3''-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID; 2-(3''-Carbamimidoyl-biphenyl-3-yl)-5-(pyridin-4-ylamino)-pentanoic acid; (2S)-2-(3'-carbamimidoylbiphenyl-3-yl)-5-(pyridin-4-ylamino)pentanoic acid; 2-(3''-Carbamimidoyl-biphenyl-3-yl)-5-(pyridin-4-ylamino)-pentanoic acid(FX-2212)
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[91] | |||
| Compound Name |
[4-((S)-1-Carbamimidoyl-pyrrolidin-3-yloxy)-phenyl]-(2-carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL147988; BDBM50068486
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
4-[(2-Carbamimidoyl-3,4-dihydro-1H-isoquinolin-7-yl)oxymethyl]-1-pyrimidin-4-ylpiperidine-4-carboxylic acid;methanesulfonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL195428
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[92] | |||
| Compound Name |
[4-((S)-1-Allyl-pyrrolidin-3-yloxy)-phenyl]-(2-carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-acetic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL342568; BDBM50068498
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
Pyrazinone Analog 24h
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL336273; BDBM14505
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[93] | |||
| Compound Name |
Darexaban glucuronide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1922344; YM-222714; SCHEMBL13206705; BDBM50358251
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[94] | |||
| Compound Name |
US9585881, Example 111
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3948872; SCHEMBL15533675; BDBM238269; BDBM294113; US9394250, 111
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
N-(5-Chloropyridine-2-yl)-2-[(1-isopropylpiperidine-4-yl)carbonylamino]-3-(beta-D-glucopyranuronosyloxy)-5-bromobenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3354240; SCHEMBL5755020; BDBM50035154
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[95] | |||
| Compound Name |
3-[3-[(1-Benzylpiperidin-4-yl)methyl]-5-(methanesulfonamido)-2-oxo-1,3-diazinan-1-yl]benzenecarboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3780273; SCHEMBL17302805; BDBM50158151
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[79] | |||
| Compound Name |
2-Ketobenzothiazole 44
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL175473; BDBM14104
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
4-[[(2S,4S)-1-(1-Carbamimidoylpiperidine-4-carbonyl)-4-(4-methylsulfonylpiperazin-1-yl)pyrrolidine-2-carbonyl]amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3889796; SCHEMBL15534247; BDBM238251; US9394250, 9
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
Benzyl (3aS,6aR)-6-allyl-5-oxohexahydropyrrolo[3,2-b]pyrrole-1(2H)-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2367635; SCHEMBL6621886; BDBM50067001; (3aS,6R)-6-Allyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester; (3R,3aalpha,6abeta)-3alpha-Allyl-4-(benzyloxycarbonyl)octahydropyrrolo[3,2-b]pyrrole-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
Ethyl 1-[4-[(5S)-5-[[(3-amino-4-chlorobenzoyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391199; BDBM50435611
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
((S)-1-{[(1-Formyl-4-guanidino-butylcarbamoyl)-methyl]-carbamoyl}-4-guanidino-butyl)-carbamic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372447; BDBM50083986
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-methyl-butyl)-3-methyl-butyramide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL168471; SCHEMBL3913553; BDBM50124010; ZINC13493521
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[96] | |||
| Compound Name |
((S)-1-{[(1-Formyl-4-guanidino-butylcarbamoyl)-methyl]-carbamoyl}-4-ureido-butyl)-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372432; BDBM50084000; (2S)-2-[(Boc-D-Cit-Gly-)Amino]-5-guanidinopentanal
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
({[2-(4-Carbamimidoyl-benzylcarbamoyl)-indan-2-ylcarbamoyl]-methyl}-amino)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL214356; BDBM50193236
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[82] | |||
| Compound Name |
trans-N-(2-(5-Chloro-1H-indole-2-carboxamido)cycloheptyl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL439391; SCHEMBL12095638; BDBM50214997
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[97] | |||
| Compound Name |
[4-[3-(Aminomethyl)phenyl]piperidin-1-yl]-[5-(2-pyridin-2-ylethynyl)furan-2-yl]methanone;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1944897
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[98] | |||
| Compound Name |
[4-(1-Acetyl-piperidin-4-yloxy)-phenyl]-(2-carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-acetic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL358566; BDBM50068497
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
N-[[(3S,3Ar)-1-oxo-7-(3-oxomorpholin-4-yl)-3a,4-dihydro-3H-[1,3]oxazolo[4,3-c][1,4]benzothiazin-3-yl]methyl]-5-chlorothiophene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3330482; BDBM50024529
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
4-[[(2S,4S)-1-[4-(Aminomethyl)cyclohexanecarbonyl]-4-(4-cyclopropylsulfonylpiperazin-1-yl)pyrrolidine-2-carbonyl]amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3926756; SCHEMBL15534112; SCHEMBL16755132; BDBM238256; US9394250, 55
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
Pyrazinone Analog 24j
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL129894; BDBM14507
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[93] | |||
| Compound Name |
3-Amino-5-[1-({[(4-carbamimidoylphenyl)methyl]carbamoyl}methyl)-3-chloro-6-oxo-5-(propan-2-ylamino)-1,6-dihydropyrazin-2-yl]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77076; Pyrazinone Analog 34; SCHEMBL14542855; BDBM14593
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[100] | |||
| Compound Name |
3-[3-[2-(1-Benzylpiperidin-4-yl)ethyl]-5-methyl-2-oxo-1,3-diazinan-1-yl]benzenecarboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3779949; BDBM50157633
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[79] | |||
| Compound Name |
Ethyl 1-[4-[(5S)-5-[[(2-amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]-3-methyl-2-oxopiperidine-3-carboxylate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391186
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
(3As,6R)-6-Allyl-4-(naphthalene-1-sulfonyl)-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL127085; BDBM50067000
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
Pyrazinone Analog 24k
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL133110; BDBM14508
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[93] | |||
| Compound Name |
1-[4-[(5R)-5-[[(2-Amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391041
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
N-(2-(3-(4-(Aminomethyl)phenyl)propylamino)ethyl)-1-chloronaphthalene-2-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL208638; BDBM50184499
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[101] | |||
| Compound Name |
2-Ketobenzothiazole 72
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3084981; BDBM14134; The absolute stereochemistry of the carbon thatbears the cyclohexyl ring is unknown
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
4-[[(2S,4R)-1-(3-Chloro-4-fluoro-1-methylindole-5-carbonyl)-4-(1-methylsulfonylpiperidin-4-yl)pyrrolidine-2-carbonyl]amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3946619; SCHEMBL16755154; BDBM238264; US9394250, 93
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
3-((S)-2-(((Benzyloxy)carbonyl)amino)-3-methylbutanamido)-5-fluoro-4-oxopentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MX1013; Z-VAL-DL-ASP-FLUOROMETHYLKETONE; CHEMBL23226; Z-Val-Asp-fmk; CASPASE INHIBITOR IX; Z-Val-Asp-Fluoromethyl Ketone; SCHEMBL4466395; EX-A500; BDBM50140543; BP-22470-B; AS-35053; BP-22470; 3-(CBz-Val-amido)-5-fluoro-4-oxo-pentanoic acid; J-690326
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[102] | |||
| Compound Name |
[(R)-1-({[2-(5-Amino-2H-[1,2,4]triazol-3-yl)-ethylcarbamoyl]-methyl}-cyclopentyl-carbamoyl)-2-cyclohexyl-ethylamino]-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL421276; BDBM50073321
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[74] | |||
| Compound Name |
[4-(1-Carbamimidoyl-piperidin-4-yloxy)-phenyl]-(2-carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148357; BDBM50068487
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
1-[4-[(5S)-2-Oxo-5-[[[4-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]methylamino]methyl]-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391190; BDBM50435621
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-(4-{1-[imino-(4-methoxy-phenyl)-methyl]-piperidin-4-yloxy}-phenyl)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL418849; BDBM50068501
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
(2S)-6-Amino-N-[(2S)-6-amino-1-[(1-carbamimidoylpiperidin-4-yl)methylamino]-1-oxohexan-2-yl]-2-[[2-(3-phenylphenyl)acetyl]amino]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2425343; BDBM50493347
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[103] | |||
| Compound Name |
(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-[4-(tetrahydro-pyran-4-yloxy)-phenyl]-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL147707; BDBM50068489
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
[4-(1-Acetyl-piperidin-4-yloxy)-phenyl]-(2-carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148972; BDBM50068495
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
(2S)-2-Hydroxy-N-[[3-[2-hydroxy-3-(1H-pyrrolo[3,2-c]pyridin-2-yl)phenyl]phenyl]methyl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL213180; BDBM50189940
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[85] | |||
| Compound Name |
2-[6-(3-Aminophenyl)-5-chloro-3-(cyclobutylamino)-2-oxo-1,2-dihydropyrazin-1-yl]-N-[(4-carbamimidoyl-3-hydroxyphenyl)methyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL230031; BDBM50215421
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[104] | |||
| Compound Name |
(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-{4-[(S)-1-(5,5-dimethyl-3-oxo-cyclohex-1-enyl)-pyrrolidin-3-yloxy]-phenyl}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL147789; BDBM50068491
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-{4-[(S)-1-(5,5-dimethyl-3-oxo-cyclohex-1-enyl)-pyrrolidin-3-yloxy]-phenyl}-acetic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL356973; BDBM50068484
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
[4-(3-Aminomethylphenyl)-piperidin-1-yl]-[5-(2-fluorophenylethynyl)-furan-2-yl]-methanone trifluoroacetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1944727; SCHEMBL6804030
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[98] | |||
| Compound Name |
3-[[3-(1-Benzylpiperidin-4-yl)-5-methyl-2-oxo-1,3-diazinan-1-yl]methyl]benzenecarboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3780277; BDBM50158163
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[79] | |||
| Compound Name |
4-[[(2S,4S)-1-[(E)-3-[5-Chloro-2-(tetrazol-1-yl)phenyl]prop-2-enoyl]-4-morpholin-4-ylpyrrolidine-2-carbonyl]amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3982298; SCHEMBL15547388; SCHEMBL15559826; BDBM238253; US9394250, 37
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
Ethyl 1-[4-[(5S)-5-[[(2-amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391038
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
4-[3-(1-Benzylpiperidin-4-yl)-5-methyl-2-oxo-1,3-diazinan-1-yl]benzenecarboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3780437; BDBM50158162
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[79] | |||
| Compound Name |
Unii-WJ9EV5WM6Q
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
WJ9EV5WM6Q; dx-9065a; CHEMBL539053; DX-9065 hydrochloride; SCHEMBL8430390
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[92] | |||
| Compound Name |
4-[5-(3,5-Bis-trifluoromethyl-benzenesulfonylamino)-1-methyl-1H-benzoimidazol-2-ylmethyl]-benzamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL48717; BDBM50112084
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[105] | |||
| Compound Name |
3-[[(3R,3Ar,6aS)-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-3-yl]methyl]benzenecarboximidamide;acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL102134
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[106] | |||
| Compound Name |
(2S,3S)-N-[(2S)-1-[[2-(Butylamino)-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]-3-methyl-2-[(2-naphthalen-2-ylacetyl)amino]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2182019; BDBM50398078
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[55] | |||
| Compound Name |
Acetic acid;ethyl 1-[4-[(5R)-5-[[(4-carbamimidoylphenyl)methylamino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391195
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
(2S)-2-[[(2S)-2-(5-Aminopentanoylamino)-3-phenylpropanoyl]amino]-N-[(2S)-1-hydroxy-3-phenylpropan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL304753; BDBM50039012
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[42] | |||
| Compound Name |
4-[[(2S,4S)-1-(4-Carbamimidoylbenzoyl)-4-(4-methylsulfonylpiperazin-1-yl)pyrrolidine-2-carbonyl]amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3912373; SCHEMBL15533470; BDBM238252; US9394250, 20
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
1-[4-[(5R)-2-Oxo-5-[[[4-(5-oxo-4H-1,2,4-oxadiazol-3-yl)benzoyl]amino]methyl]-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391189; BDBM50435622
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
(2S,4S)-1-[(E)-3-[5-Chloro-2-(tetrazol-1-yl)phenyl]prop-2-enoyl]-4-[(3S)-3-methyl-4-sulfamoylpiperazin-1-yl]-N-phenylpyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3898718; SCHEMBL15560511; SCHEMBL15560512; BDBM238257; US9394250, 57
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
US10336741, Example 96
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3934208; SCHEMBL16781418; SCHEMBL16781628; SCHEMBL19113035; BDBM238266; BDBM406677; US9394250, 96
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-[4-((S)-pyrrolidin-3-yloxy)-phenyl]-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148343; BDBM50068496
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
Tert-butyl N-[(2S)-1-[[2-[[5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-6-[methyl-(N,N,N'-trimethylcarbamimidoyl)amino]-1-oxohexan-2-yl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL290061; BDBM50084003
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
US9585881, Example 86
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3947788; SCHEMBL16781676; BDBM238262; BDBM294104; US9394250, 86
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
N-[[(3S)-1-Oxo-7-(3-oxomorpholino)-3abeta,4-dihydro-1H,3H-2,5-dioxa-9b-aza-2H-benzo[e]indene-3beta-yl]methyl]-5-chlorothiophene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3330442; SCHEMBL16609922; BDBM50024356
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
Pyrazinone Analog 24i
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL130202; BDBM14506
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[93] | |||
| Compound Name |
4'-Bromo-2'-[(5-chloro-2-pyridyl)carbamoyl]-6'-hydroxy-1-isopropylpiperidine-4-carboxanilide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3354239; SCHEMBL2473807; BDBM50035155; N-(5-Chloropyridine-2-yl)-2-[(1-isopropylpiperidine-4-yl)carbonylamino]-3-hydroxy-5-bromobenzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[95] | |||
| Compound Name |
(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-[4-(piperidin-4-yloxy)-phenyl]-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL148323; BDBM50068504; 2-[(2-carbamimidoyl-3,4-dihydro-1H-isoquinolin-7-yl)oxy]-2-(4-piperidin-4-yloxyphenyl)acetic acid
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
N-[[1-[(1-Benzylpiperidin-4-yl)methyl]-3-(3-carbamimidoylphenyl)-2-oxo-1,3-diazinan-5-yl]methyl]-2-phenylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3780269; SCHEMBL17302824; BDBM50158152
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[79] | |||
| Compound Name |
(2S,4S)-4-[4-(Benzenesulfonyl)piperazin-1-yl]-1-[(E)-3-[5-chloro-2-(tetrazol-1-yl)phenyl]prop-2-enoyl]-N-phenylpyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3965746; SCHEMBL15546069; SCHEMBL15546071; BDBM238254; US9394250, 39
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
Ethyl 1-[4-[(5R)-5-[[(3-amino-4-chlorobenzoyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391200; BDBM50435610
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
N-[[1-[(1-Benzylpiperidin-4-yl)methyl]-3-(3-carbamimidoylphenyl)-2-oxo-1,3-diazinan-5-yl]methyl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3781405; SCHEMBL17302800; BDBM50158161
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[79] | |||
| Compound Name |
3-(6-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrrolidin-3-yloxy)-phenyl]-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL279959; BDBM50041225; 4-[[(3S)-Pyrrolidin-3beta-yl]oxy]-alpha-[(6-amidino-2-naphthyl)methyl]benzeneacetic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[107] | |||
| Compound Name |
N-{[4-(N-Aminocarbamimidoyl)phenyl]methyl}-2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-2-oxo-1,2-dihydropyrazin-1-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL243108; BDBM50215435
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[104] | |||
| Compound Name |
Ketothiazole inhibitor 1
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL78053; BDBM14514; 2-[N-(Benzylsulfonyl)-D-Phe-3-(3-pyridinyl)-L-Ala-L-Arg-]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[51] | |||
| Compound Name |
CID 9937921
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
DPC423; DPC-423; DPC 423; CHEMBL559015; FT-0667794
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[108] | |||
| Compound Name |
3-(({7-[Amino(imino)methyl]-2-naphthyl}methyl)-{1-[(2,5-dimethoxyphenyl)sulfonyl]piperidin-4-yl}amino)-3-oxopropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL244640; BDBM50209900
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[109] | |||
| Compound Name |
Pyrazinone Analog 24g
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL133069; BDBM14504
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[93] | |||
| Compound Name |
1-[4-[(5R)-2-Oxo-5-[[[4-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]methylamino]methyl]-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391191; BDBM50435620
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
(2s)-3-(7-Carbamimidoylnaphthalen-2-Yl)-2-[4-({(3r)-1-[(1z)-Ethanimidoyl]pyrrolidin-3-Yl}oxy)phenyl]propanoic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
dx-9065a; UNII-RF60GS0DRO; RF60GS0DRO; CHEMBL19902; CHEMBL539053; SCHEMBL675242; BDBM17283; DX9056A; ZINC3791107; BDBM50068488; DX-9065; Q27459773
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[109] | |||
| Compound Name |
1-[4-[(5S)-2-Oxo-5-[[[4-(5-oxo-4H-1,2,4-oxadiazol-3-yl)benzoyl]amino]methyl]-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391188; BDBM50435623
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
2-[(3R)-3-Acetamido-4-oxo-2,3-dihydro-1,5-benzothiazepin-5-yl]-N-[(4-carbamimidoylphenyl)methyl]acetamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL561613
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[83] | |||
| Compound Name |
(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-{4-[(S)-1-(1-imino-ethyl)-pyrrolidin-3-yloxy]-phenyl}-acetic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL146097; BDBM50068502
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
2-Ketobenzothiazole 71
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3084980; BDBM14133; The absolute stereochemistry of the carbon thatbears the cyclohexyl ring is unknown
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
Ethyl 1-[4-[(5S)-5-[[(2-amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-3-carboxylate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391042
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
1-[4-[(5S)-5-[[(3-Amino-4-chlorobenzoyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391201; BDBM50435609
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
Acetic acid;ethyl 1-[4-[(5S)-5-[[(4-carbamimidoylbenzoyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391192
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
Methyl N-[4-[2-[(2S,4S)-1-(1-carbamimidoylpiperidine-4-carbonyl)-4-(4-methylsulfonylpiperazin-1-yl)pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3959704; SCHEMBL15607675; BDBM238268; US9394250, 98
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
[(({7-[Amino(imino)methyl]-2-naphthyl}methyl){1-[(2,5-dimethoxyphenyl)sulfonyl]piperidin-4-yl}amino)sulfonyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL244436; BDBM50209904
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[109] | |||
| Compound Name |
(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-{4-[1-(1-imino-ethyl)-piperidin-4-yloxy]-phenyl}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL344305; BDBM50068506
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
N-Butyl-3-[[4-(diaminomethylideneamino)phenyl]methylamino]imidazo[1,2-a]pyridine-7-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3740183; BDBM50499900
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[37] | |||
| Compound Name |
3-N'-Naphthalen-1-ylbenzene-1,3-dicarboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3247195; BDBM50010304
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[78] | |||
| Compound Name |
(2S)-2-[3-[2-[2-[2-[2-[5-[(3As,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-N-[(1S)-5-amino-1-diphenoxyphosphorylpentyl]butanediamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL379174; BDBM50410912
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[110] | |||
| Compound Name |
Ethyl 1-[4-[(5R)-5-[[(2-amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391040
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
2-{2-[4-((S)-Pyrrolidin-3-yloxy)-phenyl]-ethyl}-benzofuran-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL19626; BDBM50041215; 2-[2-[4-[[(3S)-Pyrrolidin-3beta-yl]oxy]phenyl]ethyl]-5-benzofurancarboxamidine
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[107] | |||
| Compound Name |
1-[4-[(5S)-5-[[(2-Amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-3-carboxylic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391183
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
2,6-Bis-(3-carbamimidoyl-phenoxy)-nicotinic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL46077; SCHEMBL6579502; 2,6-bis(3-carbamimidoylphenoxy)pyridine-3-carboxylic Acid; BDBM50077178; 2,6-bis(3-amidinophenoxy)pyridine-3-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[111] | |||
| Compound Name |
((R)-2-Cyclohexyl-1-{cyclopentyl-[(4-guanidinocarbonyl-phenylcarbamoyl)-methyl]-carbamoyl}-ethylamino)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL120012; BDBM50073318
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[74] | |||
| Compound Name |
Ethyl 1-[4-[(5S)-5-[[(5-chlorothiophene-2-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3134466
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[69] | |||
| Compound Name |
(2S,4S)-N-(2H-Benzotriazol-5-yl)-1-[(E)-3-[5-chloro-2-(tetrazol-1-yl)phenyl]prop-2-enoyl]-4-morpholin-4-ylpyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3939406; SCHEMBL15547306; SCHEMBL15547308; BDBM238255; US9394250, 43
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
2-[6-(3-Aminophenyl)-5-chloro-3-(cyclobutylamino)-2-oxo-1,2-dihydropyrazin-1-yl]-N-[(4-carbamimidoyl-2,5,6-trifluoro-3-hydroxyphenyl)methyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL230661; BDBM50215426
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[104] | |||
| Compound Name |
5-Chloro-N-(((3S,3aS)-1-oxo-7-(3-oxomorpholino)-3,3a,4,5-tetrahydro-1H-oxazolo[3,4-a]quinolin-3-yl)methyl)thiophene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3330490; DJT06001; BDBM50024538
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
Acetic acid;ethyl 1-[4-[(5R)-5-[[(4-carbamimidoylbenzoyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391193
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
((S)-1-{[(1-Formyl-4-guanidino-butylcarbamoyl)-methyl]-carbamoyl}-5-guanidino-pentyl)-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372511; BDBM50083987; (2S)-2-[(Boc-D-Lys-Gly-)Amino]-5-guanidinopentanal
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
3-[1-(5-Phenylethynyl-furan-2-carbonyl)-piperidin-4-yl]-benzylamine trifluoroacetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1944726; SCHEMBL1381804
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[98] | |||
| Compound Name |
1-[4-[(5S)-5-[[(2-Amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]-3-methyl-2-oxopiperidine-3-carboxylic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391187
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
N-[(2R,3S)-3-Amino-2-hydroxy-4-phenylbutyl]naphthalene-2-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Sulfonamide Compound 3; CHEMBL204086; BDBM12585; DB07522; Q27096742; (2R,3S)-3-amino-2-hydroxy-N-(naphthalen-2-yl)-4-phenylbutane-1-sulfonamido
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[112] | |||
| Compound Name |
3-((S)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-5-fluoro-4-oxo-pentanoic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL23453; BDBM50140548; methyl 3-([N-[(benzyloxy)carbonyl]-l-valyl]amino)-5-fluoro-4-oxopentanoate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[102] | |||
| Compound Name |
Chembl4202662
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50457932
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[100] | |||
| Compound Name |
(2S,3S,4S,5R,6S)-6-[5-Chloro-3-[(5-chloropyridin-2-yl)carbamoyl]-2-[[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino]phenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3359576; SCHEMBL13206827; BDBM50042002
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[108] | |||
| Compound Name |
N-({7-[Amino(imino)methyl]-2-naphthyl}methyl)-N-{1-[(2,5-dimethoxyphenyl)sulfonyl]piperidin-4-yl}acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL244221; BDBM50209895
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[109] | |||
| Compound Name |
{(R)-1-[6-(4-Carbamimidoyl-benzylcarbamoyl)-6,7-dihydro-5H-[2]pyrindin-6-ylcarbamoyl]-2-methyl-propylamino}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL448732; BDBM50193232
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[82] | |||
| Compound Name |
(S)-3-{4-[(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-ethoxycarbonyl-methyl]-phenoxy}-pyrrolidine-1-carboxylic acid allyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL144637; BDBM50068507
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
7-({[1-(2,5-Dimethoxy-benzenesulfonyl)-piperidin-4-yl]-methanesulfonyl-amino}-methyl)-naphthalene-2-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL244219; BDBM50209893
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[109] | |||
| Compound Name |
3-[3-(1-Benzyl-piperidin-4-yl)-ureido]-benzamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL327254; BDBM50071945
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[79] | |||
| Compound Name |
Ethyl 1-[4-[(5S)-5-[[(2-amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-2-carboxylate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391184
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
1-[4-[(5S)-5-[[(2-Amino-1,3-thiazole-5-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391039
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
3-[3-[(1-Benzylpiperidin-4-yl)methyl]-5-methoxy-2-oxo-1,3-diazinan-1-yl]benzenecarboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3781626; SCHEMBL17302804; BDBM50158156
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[79] | |||
| Compound Name |
N-((S)-1-{[(1-Formyl-4-guanidino-butylcarbamoyl)-methyl]-carbamoyl}-4-guanidino-butyl)-malonamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372435; BDBM50084001
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
1-[4-[(5R)-5-[[(3-Amino-4-chlorobenzoyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391202; BDBM50435608
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
Benzyl (3S,3aS,6aS)-1-(2-acetyloxyacetyl)-3-methyl-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]pyrrole-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL138633; 1-(2-Acetoxy-acetyl)-3-methyl-2-oxo-octahydro-cyclopenta[b]pyrrole-4-carboxylic acid benzyl ester; BDBM50094209
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[113] | |||
| Compound Name |
2-Ketobenzothiazole 24
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL180219; SCHEMBL7081704; BDBM14084; (2S)-N-[1-(1,3-benzothiazol-2-yl)-5-carbamimidamido-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[11] | |||
| Compound Name |
Acetic acid;ethyl 1-[4-[(5S)-5-[[(4-carbamimidoylphenyl)methylamino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391194
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
Acetic acid;1-[4-[(5R)-5-[[(4-carbamimidoylbenzoyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391197
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
Methyl N-[4-[2-[(2S,4R)-1-(1-carbamimidoylpiperidine-4-carbonyl)-4-(1-methylsulfonylpiperidin-4-yl)pyrrolidin-2-yl]-1H-imidazol-5-yl]phenyl]carbamate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3985511; SCHEMBL16781638; BDBM238258; US9394250, 69
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[41] | |||
| Compound Name |
N-((S)-1-{[(1-Formyl-4-guanidino-butylcarbamoyl)-methyl]-carbamoyl}-4-guanidino-butyl)-succinamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372436; BDBM50084011; (2S)-2-[(Suc-D-Arg-Gly-)Amino]-5-guanidinopentanal
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
N-[[(3S,3As)-1-oxo-7-(3-oxomorpholin-4-yl)-3,3a,4,5-tetrahydro-[1,3]oxazolo[3,4-a]quinoxalin-3-yl]methyl]-5-chlorothiophene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3330493; BDBM50024536
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[99] | |||
| Compound Name |
4-[3-[2-Oxo-2-[1-[2,4-bis(trifluoromethyl)phenyl]ethylamino]ethyl]ureido]benzamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL35754; BDBM50126572; N-[1-(2,4-Bis-trifluoromethyl-phenyl)-ethyl]-2-[3-(4-carbamimidoyl-phenyl)-ureido]-acetamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[8] | |||
| Compound Name |
Ethyl 1-[4-[(5S)-5-[[(5-chlorothiophene-2-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3134467
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[69] | |||
| Compound Name |
(S)-3-Cyano-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-butyl]-2-((R)-3-phenyl-2-phenylmethanesulfonylamino-propionylamino)-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL427751; BDBM50130055; 2-[N-(Benzylsulfonyl)-D-Phe-3-cyano-L-Ala-L-Arg-]thiazole
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[7] | |||
| Compound Name |
Darexaban
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Tanexaban; UNII-KF322K101S; CHEMBL1922235; KF322K101S; YM150; Darexaban [INN]; Tanexaban [INN]; YM-150; SCHEMBL2227024; BDBM50358252; ZINC70647134; DB12289; 462H233; Q5222570
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[94] | |||
| Compound Name |
3-(((E)-3-{3-[Amino(imino)methyl]phenyl}prop-2-en-1-yl){1-[(2,5-dimethoxyphenyl)sulfonyl]piperidin-4-yl}-amino)-3-oxopropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL244641; BDBM50209899
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[109] | |||
| Compound Name |
(2S)-5-(Diaminomethylideneamino)-N-[2-[[5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]-2-[(2-naphthalen-2-yloxyacetyl)amino]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL43014; BDBM50083996
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[14] | |||
| Compound Name |
[(R)-1-({[3-(5-Amino-2H-[1,2,4]triazol-3-yl)-propylcarbamoyl]-methyl}-cyclopentyl-carbamoyl)-2-cyclohexyl-ethylamino]-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL120029; BDBM50073317
Click to Show/Hide
|
||||
| Activity |
IC50 = 100000 nM
|
[74] | |||
| Compound Name |
2-[6-(3-Aminophenyl)-5-chloro-3-(cyclobutylamino)-2-oxo-1,2-dihydropyrazin-1-yl]-N-[(4-carbamimidoyl-2,3,5,6-tetrafluorophenyl)methyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL230764; BDBM50215428
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[104] | |||
| Compound Name |
(2-Carbamimidoyl-1,2,3,4-tetrahydro-isoquinolin-7-yloxy)-[4-((S)-pyrrolidin-3-yloxy)-phenyl]-acetic acid ethyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL144079; BDBM50068505
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[90] | |||
| Compound Name |
[(((E)-3-{3-[Amino(imino)methyl]phenyl}prop-2-en-1-yl){1-[(2,5-dimethoxyphenyl)sulfonyl]piperidin-4-yl}-amino)sulfonyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL390266; BDBM50209891
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[109] | |||
| Compound Name |
Tert-butyl 3-[3-[(4-carbamimidoylphenyl)sulfonylamino]propanoylamino]benzoate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159286
Click to Show/Hide
|
||||
| Activity |
Ki = 100000 nM
|
[26] | |||
| Compound Name |
Ethyl 1-[4-[(5S)-5-[[(5-chlorothiophene-2-carbonyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]-2-oxopiperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3134464
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[69] | |||
| Compound Name |
Acetic acid;1-[4-[(5S)-5-[[(4-carbamimidoylbenzoyl)amino]methyl]-2-oxo-1,3-oxazolidin-3-yl]phenyl]piperidine-4-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2391196
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[30] | |||
| Compound Name |
(1R,21S,24S)-21-Tert-butyl-N-[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]-16,16-dimethyl-3,19,22-trioxo-2,18-dioxa-4,20,23-triazatetracyclo[21.2.1.14,7.06,11]heptacosa-6(11),7,9-triene-24-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL599872; SCHEMBL3263999; BDBM50326055
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[114] | |||
| Compound Name |
1beta-[[4-(4-Amidinobenzylcarbamoyl)piperazino]carbonyloxy]-5beta-[4-[4-(4-piperidinyl)butyryl]piperazinocarbonyloxy]cyclooctane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42898; BDBM50101016
Click to Show/Hide
|
||||
| Activity |
Ki = 102000 nM
|
[28] | |||
| Compound Name |
(2E)-2-Cyano-3-(4-hydroxyphenyl)prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL308048; NSC117971; BDBM4355; SCHEMBL9539318; alpha-Cyano-4-hydroxycinnamamide; ZINC160670; CCG-50900; NSC638074; alpha-Cyano-4-hydroxybenzeneacrylamide; AKOS016024289; NSC-117971; NSC-638074; benzylidenemalononitrile (BMN) deriv. 39; 2-Propenamide, 2-cyano-3-(4-hydroxyphenyl)-; (2E)-2-cyano-3-(4-hydroxyphenyl)-2-propenamide; SR-01000640240-1
Click to Show/Hide
|
||||
| Activity |
Ki = 102000 nM
|
[115] | |||
| Compound Name |
(S)-5-Guanidino-N-((S)-1-((S)-5-guanidino-1-(3-guanidinopropylamino)-1-oxopentan-2-ylamino)-3-methyl-1-oxobutan-2-yl)-2-(2-phenylacetamido)pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL569280; BDBM50303777
Click to Show/Hide
|
||||
| Activity |
Ki = 102000 nM
|
[19] | |||
| Compound Name |
3-(N-Benzylsulfamoyl)Benzamidinium Chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159377
Click to Show/Hide
|
||||
| Activity |
Ki = 102000 nM
|
[26] | |||
| Compound Name |
Tert-butyl 4-[4-[(4-carbamimidoylphenyl)sulfonylamino]butanoylamino]benzoate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159287
Click to Show/Hide
|
||||
| Activity |
Ki = 103000 nM
|
[26] | |||
| Compound Name |
(S)-N-(3-Chlorobenzyl)-1-(2-cyclohexylacetyl)pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL605210; BDBM50307844
Click to Show/Hide
|
||||
| Activity |
Ki = 104000 nM
|
[32] | |||
| Compound Name |
Chembl44010
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372738; BDBM50070773
Click to Show/Hide
|
||||
| Activity |
IC50 = 106000 nM
|
[24] | |||
| Compound Name |
N-[(2R)-2-[2-[(4-Carbamimidoylphenyl)methylamino]-2-oxoethyl]-3-oxomorpholin-4-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1744057; BDBM50370271
Click to Show/Hide
|
||||
| Activity |
IC50 = 106000 nM
|
[33] | |||
| Compound Name |
2-Guanidinoethyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL205161; BDBM50180537
Click to Show/Hide
|
||||
| Activity |
IC50 = 107000 nM
|
[116] | |||
| Compound Name |
4-(4-Guanidinobenzoyloxy)phenylacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Foy 251; 4-GBCE (methanesulfonate); 2-(4-((4-Guanidinobenzoyl)oxy)phenyl)acetic acid methanesulfonic acid salt; CHEMBL433135; Foy-251; {4-[(4-carbamimidamidobenzoyl)oxy]phenyl}acetic acid methanesulfonate(1:1); FOY 251Camostat metabolite; SCHEMBL1649708; SCHEMBL11417275; CTK8D7311; DTXSID20991365; HY-19727A; CS-0016501; FT-0668867
Click to Show/Hide
|
||||
| Activity |
IC50 = 107500 nM
|
[117] | |||
| Compound Name |
(2S)-N-(3-Imidazol-1-ylpropyl)-1-[(2R)-2-(methanesulfonamido)-3-phenylpropanoyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL144702; BDBM50107467
Click to Show/Hide
|
||||
| Activity |
IC50 = 108000 nM
|
[118] | |||
| Compound Name |
Cyclohex-2-ene-1,2-dicarboxylic acid 2-benzylamide 1-(4-carbamimidoyl-benzylamide)
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17475; BDBM50125854
Click to Show/Hide
|
||||
| Activity |
IC50 = 109000 nM
|
[44] | |||
| Compound Name |
N-(3-Chlorobenzyl)-1-(4-Methylpentanoyl)-L-Prolinamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1229677; SCHEMBL21067546; DB06868; Q27095774; 16U
Click to Show/Hide
|
||||
| Activity |
Ki = 109000 nM
|
[38] | |||
| Compound Name |
Chembl296659
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372689; BDBM50070745
Click to Show/Hide
|
||||
| Activity |
IC50 = 109000 nM
|
[24] | |||
| Compound Name |
N-[2-(3-Carbamimidoyl-phenoxy)-ethyl]-4-(pyrrolidine-1-carbonyl)-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55770; SCHEMBL14132262; BDBM50127504
Click to Show/Hide
|
||||
| Activity |
Ki = 110000 nM
|
[29] | |||
| Compound Name |
N-(Trifluoromethylsulfonyl)-D-Phe-L-Pro-(4-guanidinobutyl)NH2
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL341641; BDBM50107465
Click to Show/Hide
|
||||
| Activity |
IC50 = 110000 nM
|
[118] | |||
| Compound Name |
1beta-[[4-(4-Amidinobenzylcarbamoyl)piperazino]carbonyloxy]-5beta-[4-[2-(4-piperidinyl)ethylcarbamoyl]piperazinocarbonyloxy]cyclooctane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40491; BDBM50101019
Click to Show/Hide
|
||||
| Activity |
Ki = 111000 nM
|
[28] | |||
| Compound Name |
1beta,5beta-Bis[4-[2-(1-amidino-4-piperidinyl)ethylcarbamoyl]piperazinocarbonyloxy]cyclooctane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77043; SCHEMBL7425638; BDBM50093181
Click to Show/Hide
|
||||
| Activity |
Ki = 112000 nM
|
[119] | |||
| Compound Name |
2-(1H-Benzo[d]imidazol-2-yl)-1H-benzo[d]imidazole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL202010; BDBM50176244
Click to Show/Hide
|
||||
| Activity |
Ki = 113000 nM
|
[52] | |||
| Compound Name |
N-[(2S)-1-(4-Methylpiperidin-1-yl)-1-oxo-5-(pyrimidin-2-ylamino)pentan-2-yl]naphthalene-2-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL68474; SCHEMBL7332835; BDBM50403289
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 115000 nM
|
[120] | |||
| Compound Name |
Tert-butyl 3-[4-[(4-carbamimidoylphenyl)sulfonylamino]butanoylamino]benzoate;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159288
Click to Show/Hide
|
||||
| Activity |
Ki = 115000 nM
|
[26] | |||
| Compound Name |
3-[2-(4-Carbamimidoylbenzyloxy)-4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carbonylamino]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL460567; BDBM50253779
Click to Show/Hide
|
||||
| Activity |
Ki = 118000 nM
|
[121] | |||
| Compound Name |
N-(2-Phenoxyethyl)pyridin-4-amine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL285311; SCHEMBL6672805; BDBM50289374; ZINC28754772; AKOS010879683; (2-Phenoxy-ethyl)-pyridin-4-yl-amine; MCULE-7251389328; Z1317598163
Click to Show/Hide
|
||||
| Activity |
Ki = 120000 nM
|
[122] | |||
| Compound Name |
N-(4-Amidinophenyl)-2-hydroxy-3-phenylbenzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL292300; BDBM50115906; 2-Hydroxy-biphenyl-3-carboxylic acid (4-carbamimidoyl-phenyl)-amide
Click to Show/Hide
|
||||
| Activity |
Ki = 120000 nM
|
[123] | |||
| Compound Name |
3-[(3,4-Dimethoxyphenyl)sulfamoyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159376
Click to Show/Hide
|
||||
| Activity |
Ki = 120000 nM
|
[26] | |||
| Compound Name |
Chembl2332610
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2448530; BDBM50431220
Click to Show/Hide
|
||||
| Activity |
Ki ~ 120000 nM
|
[124] | |||
| Compound Name |
Chembl2332604
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2448529; BDBM50431213
Click to Show/Hide
|
||||
| Activity |
Ki ~ 120000 nM
|
[124] | |||
| Compound Name |
{[2-(4-Carbamimidoyl-benzylcarbamoyl)-cyclopent-1-enecarbonyl]-o-tolyl-amino}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17068; BDBM50125875
Click to Show/Hide
|
||||
| Activity |
IC50 = 120000 nM
|
[44] | |||
| Compound Name |
Sodium;[6-ethoxy-3-ethoxycarbonyl-2-[(6-ethoxy-3-ethoxycarbonyl-2-methyl-1-benzofuran-5-yl)oxymethyl]-1-benzofuran-5-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812014
Click to Show/Hide
|
||||
| Activity |
IC50 = 120226.44 nM
|
[50] | |||
| Compound Name |
1,4-Bis[4-(4-guanidinobenzylcarbamoyl)piperazinocarbonyloxymethyl]bicyclo[2.2.2]octane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL432172; SCHEMBL7965007; BDBM50093156
Click to Show/Hide
|
||||
| Activity |
Ki = 123000 nM
|
[119] | |||
| Compound Name |
3-Bromo-N-(4-guanidino-phenyl)-2-hydroxy-5-methyl-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64578; BDBM50115893; N-(4-Guanidinophenyl)-2-hydroxy-3-bromo-5-methylbenzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 125000 nM
|
[123] | |||
| Compound Name |
N-[(4-Carbamimidoylphenyl)methyl]-2-[(4-carbamimidoylphenyl)sulfonylamino]acetamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159362
Click to Show/Hide
|
||||
| Activity |
Ki = 125000 nM
|
[26] | |||
| Compound Name |
[1-{[(2-Aminomethyl-5-chloro-benzylcarbamoyl)-methyl]-carbamoyl}-3-(1-oxy-pyridin-2-yl)-propylamino]-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL397251; SCHEMBL8241691; BDBM50211554
Click to Show/Hide
|
||||
| Activity |
Ki = 125000 nM
|
[84] | |||
| Compound Name |
Methyl 3-[4-[(6-carbamoylnaphthalene-2-carbonyl)amino]phenyl]benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1945669; BDBM50363656
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 125000 nM
|
[4] | |||
| Compound Name |
2-[4-[2-Diphenoxyphosphoryl-2-(methanesulfonamido)ethyl]phenyl]guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL238493; BDBM50228421; diphenyl 1-(methylsulfonylamino)-2-(4-guanidinophenyl)-ethanephosphonate
Click to Show/Hide
|
||||
| Activity |
IC50 = 125000 nM
|
[125] | |||
| Compound Name |
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-6-Amino-2-[(2,5-dihydroxybenzoyl)amino]hexanoyl]amino]propanoyl]amino]-3-methylpentanoyl]amino]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372668
Click to Show/Hide
|
||||
| Activity |
IC50 = 126000 nM
|
[24] | |||
| Compound Name |
Sodium;[3-ethoxycarbonyl-2-[[3-ethoxycarbonyl-6-methoxy-2-(morpholin-4-ylmethyl)-1-benzofuran-5-yl]oxymethyl]-6-methoxy-1-benzofuran-5-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812016
Click to Show/Hide
|
||||
| Activity |
IC50 = 128824.96 nM
|
[50] | |||
| Compound Name |
N-[4-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-guanidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL384180; BDBM50192103
Click to Show/Hide
|
||||
| Activity |
IC50 = 129000 nM
|
[126] | |||
| Compound Name |
Chembl4204525
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL916150; BDBM50457939; 1-methyl-6-(2-methylphenyl)pyrazolo[3,4-d][1,3]oxazin-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 129000 nM
|
[100] | |||
| Compound Name |
Cyclohex-2-ene-1,2-dicarboxylic acid 1-(4-carbamimidoyl-benzylamide) 2-phenylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL17515; BDBM50125844
Click to Show/Hide
|
||||
| Activity |
IC50 = 130000 nM
|
[44] | |||
| Compound Name |
Chembl4217251
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455313
Click to Show/Hide
|
||||
| Activity |
IC50 = 130000 nM
|
[127] | |||
| Compound Name |
2-[(3R)-3-Acetamido-4-oxo-2,3-dihydro-1,5-benzothiazepin-5-yl]-N-[(6-amino-2-methylpyridin-3-yl)methyl]acetamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL562093
Click to Show/Hide
|
||||
| Activity |
IC50 = 130000 nM
|
[83] | |||
| Compound Name |
1beta,5beta-Bis[4-(1-amidino-4-piperidinylacetyl)piperazinocarbonyloxy]cyclooctane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL75635; SCHEMBL7958531; BDBM50093168
Click to Show/Hide
|
||||
| Activity |
Ki = 130000 nM
|
[119] | |||
| Compound Name |
Cyclohex-2-ene-1,2-dicarboxylic acid 1-(4-carbamimidoyl-benzylamide) 2-cyclohexylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL278282; BDBM50125850
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 130000 nM
|
[44] | |||
| Compound Name |
2-(2,3-Dihydro-indole-1-carbonyl)-cyclopent-1-enecarboxylic acid 4-carbamimidoyl-benzylamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL277051; BDBM50125872
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 130000 nM
|
[44] | |||
| Compound Name |
N-(4-Amidinobenzyl)-N'-benzylcyclopentane-1alpha,2beta-dicarboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL49130; BDBM50087842; (+) Cyclopentane-1,2-dicarboxylic acid 1-benzylamide 2-(4-carbamimidoyl-benzylamide)
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 132000 nM
|
[128] | |||
| Compound Name |
{[2-(4-Carbamimidoyl-benzylcarbamoyl)-cyclopentanecarbonyl]-amino}-phenyl-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL49050; BDBM50087836
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 132000 nM
|
[128] | |||
| Compound Name |
N-[(2R)-1-[4-(2-Hydroxyethyl)piperidin-1-yl]-1-oxo-3-pyridin-4-ylpropan-2-yl]-3,3-dimethyl-2,4-dihydro-1H-quinoline-8-sulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1907780; BDBM50366645
Click to Show/Hide
|
||||
| Activity |
Ki = 132700 nM
|
[47] | |||
| Compound Name |
N-[(4-Carbamimidoylphenyl)methyl]-2-[(2R)-3-oxo-4-(phenacylamino)morpholin-2-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1744056; BDBM50370262
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 133000 nM
|
[33] | |||
| Compound Name |
2-[(3S)-3-Acetamido-4-oxo-2,3-dihydro-1,5-benzothiazepin-5-yl]-N-[(6-amino-2-methylpyridin-3-yl)methyl]acetamide;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL562901
Click to Show/Hide
|
||||
| Activity |
IC50 = 133000 nM
|
[83] | |||
| Compound Name |
[(R)-2-Cyclohexyl-1-(cyclopentyl-{[(piperidin-4-ylmethyl)-carbamoyl]-methyl}-carbamoyl)-ethylamino]-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL331930; BDBM50073314
Click to Show/Hide
|
||||
| Activity |
IC50 = 133000 nM
|
[74] | |||
| Compound Name |
Chembl4208864
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL915758; BDBM50457930; 2-(2,6-difluorophenyl)-7-(trifluoromethyl)-3,1-benzoxazin-4-one; 2-(2,6-Difluorophenyl)-7-(trifluoromethyl)-4H-3,1-benzoxazine-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 = 134000 nM
|
[100] | |||
| Compound Name |
Chembl4218199
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455290
Click to Show/Hide
|
||||
| Activity |
IC50 = 134000 nM
|
[127] | |||
| Compound Name |
Chembl4208441
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455298
Click to Show/Hide
|
||||
| Activity |
IC50 = 134000 nM
|
[127] | |||
| Compound Name |
(2S)-N-[2-(1H-Imidazol-5-yl)ethyl]-1-[(2R)-2-(methanesulfonamido)-3-phenylpropanoyl]pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL144983; BDBM50107457
Click to Show/Hide
|
||||
| Activity |
IC50 = 134000 nM
|
[118] | |||
| Compound Name |
(2S)-1-[(2R)-2-Amino-4-methylpentyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3422999; BDBM50082525
Click to Show/Hide
|
||||
| Activity |
Ki = 136000 nM
|
[32] | |||
| Compound Name |
Chembl296538
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372672; BDBM50070741
Click to Show/Hide
|
||||
| Activity |
IC50 = 137000 nM
|
[24] | |||
| Compound Name |
(3Aalpha,6aalpha)-3beta,6beta-Bis[4-(4-guanidinobenzylcarbamoyl)piperazinocarbonyloxy]hexahydrofuro[3,2-b]furan
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL306620; apc2059; BDBM50093153
Click to Show/Hide
|
||||
| Activity |
Ki = 138000 nM
|
[119] | |||
| Compound Name |
[(2S,3S)-3-[[4-[[4-(Diaminomethylideneamino)phenyl]methylcarbamoyl]piperazine-1-carbonyl]oxymethyl]-2-bicyclo[2.2.2]oct-5-enyl]methyl 4-[[4-(diaminomethylideneamino)phenyl]methylcarbamoyl]piperazine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77007; BDBM50093182
Click to Show/Hide
|
||||
| Activity |
Ki = 138000 nM
|
[119] | |||
| Compound Name |
2-(Benzylsulfonylamino)-4-(1-oxidopyridin-1-ium-2-yl)-N-[2-oxo-2-(thiophen-2-ylmethylamino)ethyl]butanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL231089; BDBM50211569
Click to Show/Hide
|
||||
| Activity |
Ki = 140000 nM
|
[84] | |||
| Compound Name |
3-[4-Carbamimidoyl-2-[2-[(1-pyridin-4-ylpiperidine-4-carbonyl)amino]ethoxy]phenyl]-2-oxopropanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL55500; SCHEMBL14132328; BDBM50127494
Click to Show/Hide
|
||||
| Activity |
Ki = 140000 nM
|
[29] | |||
| Compound Name |
N-[1-{[(2-Aminomethyl-5-chloro-benzylcarbamoyl)-methyl]-carbamoyl}-3-(1-oxy-pyridin-2-yl)-propyl]-malonamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL230025; SCHEMBL10020336; BDBM50211583
Click to Show/Hide
|
||||
| Activity |
Ki = 140000 nM
|
[84] | |||
| Compound Name |
1beta,5beta-Bis[4-(1-amidino-4-piperidinylmethylcarbamoyl)piperazinocarbonyloxy]cyclooctane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77949; SCHEMBL7962399; BDBM50093162
Click to Show/Hide
|
||||
| Activity |
Ki = 146000 nM
|
[119] | |||
| Compound Name |
Sodium;[2-[[6-methoxy-3-[(2-methylpropan-2-yl)oxycarbonyl]-1-benzofuran-5-yl]oxymethyl]-1,3-benzothiazol-6-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3359897
Click to Show/Hide
|
||||
| Activity |
IC50 = 146000 nM
|
[129] | |||
| Compound Name |
2-[3-(1H-1,3-Benzodiazol-2-yl)-4-hydroxy-5-(3-nitrophenyl)phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
benzimidazole 3; CHEMBL382387; BDBM13779; 2-[3-(1,3-dihydrobenzimidazol-2-ylidene)-5-(3-nitrophenyl)-4-oxocyclohexa-1,5-dien-1-yl]acetic acid
Click to Show/Hide
|
||||
| Activity |
Ki ~ 150000 nM
|
[130] | |||
| Compound Name |
2-[(S)-3-(3-Guanidino-propyl)-2,5-dioxo-piperazin-1-yl]-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL351209; BDBM50125040
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[48] | |||
| Compound Name |
4-Amino-N-[(2R)-2-[2-[(4-carbamimidoylphenyl)methylamino]-2-oxoethyl]-3-oxomorpholin-4-yl]benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1744049; BDBM50370267
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[33] | |||
| Compound Name |
2-[3-(5-Carbamimidoyl-1H-1,3-benzodiazol-2-yl)-4-hydroxy-5-(3-nitrophenyl)phenyl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL207720; amidine-containing inhibitor 1; SCHEMBL6689093; BDBM13776
Click to Show/Hide
|
||||
| Activity |
Ki ~ 150000 nM
|
[130] | |||
| Compound Name |
N-[(2S)-6-Amino-1-[5-[[4-[2-(3,4-dichlorophenyl)ethoxy]phenyl]methyl]-1,2,4-oxadiazol-3-yl]-1-oxohexan-2-yl]-3,4-difluorobenzamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL536972
Click to Show/Hide
|
||||
| Activity |
Ki ~ 150000 nM
|
[131] | |||
| Compound Name |
2-(3-{5-Amino-1H-imidazo[4,5-b]pyridin-2-yl}-4-hydroxy-5-(3-nitrophenyl)phenyl)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
imidazopyridine analog 4; CHEMBL426676; BDBM13780
Click to Show/Hide
|
||||
| Activity |
Ki ~ 150000 nM
|
[130] | |||
| Compound Name |
2-(2-Pyridylmethyl)-6-amidino-1H-benzoimidazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL204126; APD-5; SCHEMBL6162109; BDBM16307; 2-(pyridin-2-ylmethyl)-1H-benzimidazole-6-carboximidamide; 2-(pyridin-2-ylmethyl)-3H-benzimidazole-5-carboximidamide; 2-(pyridin-2-ylmethyl)-1H-1,3-benzodiazole-6-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki ~ 150000 nM
|
[52] | |||
| Compound Name |
2-[(S)-3-(3-Guanidino-propyl)-2-oxo-piperazin-1-yl]-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL163407; BDBM50125038
Click to Show/Hide
|
||||
| Activity |
IC50 = 150000 nM
|
[51] | |||
| Compound Name |
4-Guanidinophenyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL205702; BDBM50180541
Click to Show/Hide
|
||||
| Activity |
IC50 = 151000 nM
|
[116] | |||
| Compound Name |
(S)-2-{(S)-2-[(S)-2-(5-Guanidino-pentanoylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-phenyl-propionic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL63163; BDBM50039008
Click to Show/Hide
|
||||
| Activity |
IC50 = 154000 nM
|
[42] | |||
| Compound Name |
(S)-N-(3-Chlorobenzyl)-1-(3-methylbutanoyl)pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL598415; BDBM50307840
Click to Show/Hide
|
||||
| Activity |
Ki = 155000 nM
|
[38] | |||
| Compound Name |
Octasodium;[2-(3,4-disulfonatooxyphenyl)-5-[[4-[[2-(3,4-disulfonatooxyphenyl)-4-oxo-3,7-disulfonatooxychromen-5-yl]oxymethyl]phenyl]methoxy]-4-oxo-3-sulfonatooxychromen-7-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4084933; BDBM50260048
Click to Show/Hide
|
||||
| Activity |
IC50 = 156000 nM
|
[132] | |||
| Compound Name |
3-Phenylbenzenecarboximidamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BIPHENYL-3-CARBOXAMIDINE; CHEMBL3247187; [1,1'-Biphenyl]-3-carboximidamide; 1,1'-Biphenyl-3-carboxamidine; SCHEMBL14676446; CTK1A1588; 3-phenylbenzene-1-carboximidamide; DTXSID30393699; ZINC1437951; BDBM50010252; AKOS006293461
Click to Show/Hide
|
||||
| Activity |
Ki = 158489.32 nM
|
[78] | |||
| Compound Name |
(2S)-1-[(2S)-2-[[3-(3-Aminopropanoylamino)phenyl]sulfonylamino]-3-(3-carbamimidoylphenyl)propanoyl]piperidine-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL495010; BDBM50257811
Click to Show/Hide
|
||||
| Activity |
Ki = 159000 nM
|
[72] | |||
| Compound Name |
2-[[(2S,3S)-2-[[(2S)-1-[(2S)-6-Amino-2-[(2,5-dihydroxybenzoyl)amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-methylpentanoyl]amino]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372654
Click to Show/Hide
|
||||
| Activity |
IC50 = 160000 nM
|
[24] | |||
| Compound Name |
3-(N-Phenylsulfamoyl)Benzamidinium Chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159373
Click to Show/Hide
|
||||
| Activity |
Ki = 160000 nM
|
[26] | |||
| Compound Name |
Acetic acid;(2S)-N-[(4-carbamimidoylphenyl)methyl]-1-sulfamoylpyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4089232; BDBM50259720
Click to Show/Hide
|
||||
| Activity |
Ki = 163000 nM
|
[45] | |||
| Compound Name |
3-[(3-Methoxyphenyl)methylsulfamoyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159379
Click to Show/Hide
|
||||
| Activity |
Ki = 165000 nM
|
[26] | |||
| Compound Name |
2-[2-Hydroxy-3-(cyclopentyloxy)phenyl]-6-chloro-1H-benzimidazole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL305349; BDBM50115864; 6-Chloro-2-(3-cyclopentyloxy-2-hydroxy-phenyl)-1H-benzoimidazole-5-carboxamidine
Click to Show/Hide
|
||||
| Activity |
Ki = 165000 nM
|
[9] | |||
| Compound Name |
3-[(3-Methoxyphenyl)sulfamoyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159375
Click to Show/Hide
|
||||
| Activity |
Ki = 165000 nM
|
[26] | |||
| Compound Name |
(2E)-2-Cyano-3-[4-(propan-2-yl)phenyl]-N-(tetrahydrofuran-2-ylmethyl)prop-2-enamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927348; BDBM50359735; STK804925; AKOS000526877; AKOS016195711; SR-01000359920; SR-01000359920-1; 2-CYANO-3-(4-ISOPROPYLPHENYL)-N-(TETRAHYDRO-2-FURANYLMETHYL)ACRYLAMIDE
Click to Show/Hide
|
||||
| Activity |
Ki = 165000 nM
|
[115] | |||
| Compound Name |
Chembl4214557
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455302
Click to Show/Hide
|
||||
| Activity |
IC50 = 168000 nM
|
[127] | |||
| Compound Name |
Chembl45061
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372740; BDBM50070742
Click to Show/Hide
|
||||
| Activity |
IC50 = 168000 nM
|
[24] | |||
| Compound Name |
Chembl416824
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372716; BDBM50070695
Click to Show/Hide
|
||||
| Activity |
IC50 = 169000 nM
|
[24] | |||
| Compound Name |
N-[3-(3-Amino-propoxy)-5-methyl-phenyl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL417167; BDBM50070631
Click to Show/Hide
|
||||
| Activity |
Ki = 170000 nM
|
[133] | |||
| Compound Name |
(2R)-2-(Benzylcarbamoylamino)-5-(diaminomethylideneamino)-N-[2-[[(2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372442; BDBM50084005
Click to Show/Hide
|
||||
| Activity |
IC50 = 170000 nM
|
[14] | |||
| Compound Name |
Palladium analogue
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL313246; BDBM50071643
Click to Show/Hide
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||||
| Activity |
Ki = 170000 nM
|
[134] | |||
| Compound Name |
Boc-D-Ser-Gly-(4-Amidinobenzyl)NH2
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL440919; BDBM50110004
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| Activity |
Ki = 170000 nM
|
[67] | |||
| Compound Name |
2-[(4-Carbamimidoylphenyl)sulfonylamino]-N-[(3,4-dimethoxyphenyl)methyl]acetamide;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159383
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| Activity |
Ki = 172000 nM
|
[26] | |||
| Compound Name |
Tert-butyl 4-[3-[(4-carbamimidoylphenyl)sulfonylamino]propanoylamino]benzoate;2,2,2-trifluoroacetic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159285
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||||
| Activity |
Ki = 174000 nM
|
[26] | |||
| Compound Name |
3-[(4-Carbamimidoylphenyl)sulfonylamino]-N-[(3,4-dimethoxyphenyl)methyl]propanamide;hydrochloride
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159385
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||||
| Activity |
Ki = 175000 nM
|
[26] | |||
| Compound Name |
Boc-Darg-Gly-Arg-Cho
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372454; BDBM50083992; (2S)-2-[(Boc-D-Arg-Gly-)Amino]-5-guanidinopentanal
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||||
| Activity |
IC50 = 180000 nM
|
[14] | |||
| Compound Name |
Chembl44990
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372747; BDBM50070716
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||||
| Activity |
IC50 = 183000 nM
|
[24] | |||
| Compound Name |
N-(4-Carbamimidoyl-phenyl)-2-hydroxy-5-nitro-benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL62736; BDBM50115879
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||||
| Activity |
Ki = 185000 nM
|
[123] | |||
| Compound Name |
3-[(4-Carbamimidoylphenyl)sulfonylamino]-N-(3,4-dimethoxyphenyl)propanamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159382
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||||
| Activity |
Ki = 187000 nM
|
[26] | |||
| Compound Name |
2-(Benzylsulfonylamino)-N-[2-[(5-chlorothiophen-2-yl)methylamino]-2-oxoethyl]-4-(1-oxidopyridin-1-ium-2-yl)butanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL231088; BDBM50211558
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||||
| Activity |
Ki = 190000 nM
|
[84] | |||
| Compound Name |
Chembl296946
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372743; BDBM50070708
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||||
| Activity |
IC50 = 194000 nM
|
[24] | |||
| Compound Name |
3-Hydroxy-4-methoxy-anthracene-2-carboxylic acid (6-guanidino-pyridin-3-yl)-amide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL294509; BDBM50115905
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||||
| Activity |
Ki = 195000 nM
|
[123] | |||
| Compound Name |
Chembl44715
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372655; BDBM50070766
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||||
| Activity |
IC50 = 195000 nM
|
[24] | |||
| Compound Name |
D-Ser-Gly-(4-Amidinobenzyl)NH2
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL160944; BDBM50110018
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||||
| Activity |
Ki = 200000 nM
|
[67] | |||
| Compound Name |
Chembl46614
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372662; BDBM50070732
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|
||||
| Activity |
IC50 = 200000 nM
|
[24] | |||
| Compound Name |
N-[(2S)-5-(Diaminomethylideneamino)-1-oxo-1-(1,3-thiazol-2-yl)pentan-2-yl]-2-[(3R)-3-[3-(diaminomethylideneamino)propyl]-2-oxopiperazin-1-yl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL404534; BDBM50374342
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|
||||
| Activity |
IC50 = 200000 nM
|
[51] | |||
| Compound Name |
2-[(R)-3-(3-Guanidino-propyl)-2,5-dioxo-piperazin-1-yl]-N-[(S)-4-guanidino-1-(thiazole-2-carbonyl)-butyl]-acetamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL162518; BDBM50125034
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||||
| Activity |
IC50 = 200000 nM
|
[48] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 216 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Amiloride
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|
Approved | Compound Info | ||
| Synonyms |
Amiclaran; Amilorida; Amiloridum; Amipramidin; Amipramizid; Amipramizide; Amiprazidine; Amyloride; Guanamprazin; Guanamprazine; Midamor; Amiloride HCL; Amiloride hydrochloride hydrate; Amiclaran (TN); Amikal (Hydrochloride dihydrate); Amilorida [INN-Spanish]; Amiloride (INN); Amiloride [INN:BAN]; Amiloridum [INN-Latin]; Biduret (TN); Midamor (Hydrochloride dihydrate); MK-870 (Hydrochloride dihydrate); AMILORIDE (SEE ALSO: AMILORIDE HCL (2016-88-8)); N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide; N-Amidino-3,5-diamino-6-chlorpyrazincarboxamid; Pyrazinecarboxamide, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-, monohydrochloride; 3,5-Diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide; 3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide; 3,5-diamino-N-[amino(imino)methyl]-6-chloropyrazine-2-carboxamide; 3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-carboxamide; Amiloride (Na-Ca chanel blocker)
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||||
| Activity |
IC50 >> 250000 nM
|
[135] | |||
| Compound Name |
Benzamidine
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Investigative | Compound Info | ||
| Synonyms |
benzamidine; Benzimidamide; Benzenecarboximidamide; 618-39-3; Phenylamidine; UNII-KUE3ZY3J1F; NSC 243704; CCRIS 2952; Benzamidine (Protonated); EINECS 210-546-3; KUE3ZY3J1F; CHEMBL20936; CHEBI:41033; PXXJHWLDUBFPOL-UHFFFAOYSA-N; BDN; 1oss; 2ast; 1bra; Benzenecarboxamidine; 1v2m; 1v2j; 1h4w; 1ce5; 1c5o; 2j9n; 1f5k; 1c5p; 1v2v; 1v2s; 1v2l; 1c5z; 1v2u; AC1L1DFX; Lopac-B-6506; ACMC-1B9LG; SCHEMBL9207; Lopac0_000203; MLS001066369; GTPL7566; AC1Q1U98; DTXSID8045012; 1670-14-0 (hydrochloride); ZINC36634; CTK2F5055; 1w80; 1j16; 1j15; MolPort-000-001-395
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|
||||
| Activity |
Ki = 220000 nM
|
[122] | |||
| Compound Name |
Chembl4209404
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL7393864; BDBM50457938; 2-(2,6-difluorophenyl)pyrido[3,4-d][1,3]oxazin-4-one
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||||
| Activity |
IC50 > 200000 nM
|
[100] | |||
| Compound Name |
4-Acetyl-1-[1-(5-dimethylamino-naphthalene-1-sulfonyl)-pyrrolidine-2-carbonyl]-6-methyl-hexahydro-cyclopenta[b]pyrrol-5-one
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL301610; BDBM50107914
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|
||||
| Activity |
IC50 > 200000 nM
|
[136] | |||
| Compound Name |
(3S,3Ar,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-dimethylamino-naphthalene-1-sulfonyl)-pyrrolidine-2-carbonyl]-3-methyl-hexahydro-pyrrolo[3,2-b]pyrrol-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL299435; SCHEMBL7404125; BDBM50107904
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|
||||
| Activity |
IC50 > 200000 nM
|
[136] | |||
| Compound Name |
5-[[(2S)-1-Amino-4-methyl-1-oxopentan-2-yl]carbamoyl]-2-[2-[(3-carbamoylphenyl)carbamoyl]-4-(methylamino)phenyl]benzoic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL388161; BDBM50197325
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|
||||
| Activity |
IC50 > 200000 nM
|
[137] | |||
| Compound Name |
(3R,6As)-3-Allyl-2-oxo-hexahydro-furo[3,2-b]pyrrole-4-carboxylic acid ethyl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL127027; BDBM50066998
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||||
| Activity |
IC50 > 200000 nM
|
[1] | |||
| Compound Name |
Chembl4216440
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Investigative | Compound Info | ||
| Synonyms |
ZINC7984087; BDBM50459510; AKOS001216084; MCULE-4021787042; Z76818846
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||||
| Activity |
IC50 > 200000 nM
|
[13] | |||
| Compound Name |
Chembl4211470
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Investigative | Compound Info | ||
| Synonyms |
ZINC9670559; BDBM50459513; AKOS001221230; MCULE-9165584447
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||||
| Activity |
IC50 > 200000 nM
|
[13] | |||
| Compound Name |
3alpha-(4-Amidinobutyl)-1,2,3,3aalpha,8,8abeta-hexahydroindeno[2,1-b]pyrrole-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL46649; BDBM50078559; 5-((3R,3aS,8aS)-2-Oxo-1,2,3,3a,8,8a-hexahydro-indeno[2,1-b]pyrrol-3-yl)-pentanamidine
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||||
| Activity |
IC50 > 200000 nM
|
[138] | |||
| Compound Name |
(12E)-20-Amino-22-methyl-6-(pyrazol-1-ylmethyl)-9,17-dioxa-1,21,25,29-tetrazatetracyclo[25.2.1.03,8.018,23]triaconta-3(8),4,6,12,18,20,22,27(30),28-nonaen-26-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883423; BDBM50210074
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|
||||
| Activity |
IC50 > 200000 nM
|
[139] | |||
| Compound Name |
20-Amino-22-methyl-6-(pyrazol-1-ylmethyl)-9,17-dioxa-1,21,25,29-tetrazatetracyclo[25.2.1.03,8.018,23]triaconta-3(8),4,6,13,18,20,22,27(30),28-nonaen-26-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883788; BDBM50210075
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||||
| Activity |
IC50 > 200000 nM
|
[139] | |||
| Compound Name |
[2-[(3,5-Dimethyl-1-phenylpyrazol-4-yl)amino]-2-oxoethyl] 2-phenylacetate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1883669; MLS001161429; SCHEMBL20037216; HMS3010I19; BDBM50459509; AKOS001192799; MCULE-6355232739; SMR000707769
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||||
| Activity |
IC50 > 200000 nM
|
[13] | |||
| Compound Name |
Substituted biphenyl derivative, 21
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL224485; SCHEMBL7656938; BDBM31459; 2-[2-[(4-carbamimidoylphenyl)carbamoyl]phenyl]-5-(2-methylpropylcarbamoyl)benzoic acid
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[137] | |||
| Compound Name |
(S)-2-{(S)-2-[(S)-2-(6-Guanidino-hexanoylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-phenyl-propionic acid methyl ester
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL67406; BDBM50039017
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||||
| Activity |
IC50 > 200000 nM
|
[42] | |||
| Compound Name |
alpha-Ketothiazole analogue 27
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL216110; BDBM12967
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|
||||
| Activity |
IC50 > 200000 nM
|
[140] | |||
| Compound Name |
5-[[(2S)-1-Amino-4-methyl-1-oxopentan-2-yl]carbamoyl]-2-[2-[[4-(aminomethyl)phenyl]carbamoyl]-4-(methylamino)phenyl]benzoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL426187; BDBM50197324
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|
||||
| Activity |
IC50 > 200000 nM
|
[137] | |||
| Compound Name |
Chembl4218188
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL914839; BDBM50457937; 4H-Pyrimido[4,5-d][1,3]oxazin-4-one,7-(ethylthio)-2-(2-fluorophenyl)-; 7-ethylsulfanyl-2-(2-fluorophenyl)pyrimido[4,5-d][1,3]oxazin-4-one
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[100] | |||
| Compound Name |
2-[2-[(3-Carbamoylphenyl)carbamoyl]-4-(methylamino)phenyl]-5-[[(1S)-1-carboxy-3-methylbutyl]carbamoyl]benzoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL376806; BDBM50197327
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|
||||
| Activity |
IC50 > 200000 nM
|
[137] | |||
| Compound Name |
(S)-2-[(3As,6S,6aR)-6-Methyl-4-((2R,3S)-2-(S)-methyl-3-methyl-cyclopropanecarbonyl)-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl]-pyrrolidine-1-carboxylic acid (4-isopropyl-phenyl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL139571; CHEMBL141639; BDBM50133947; BDBM50133957
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|
||||
| Activity |
IC50 > 200000 nM
|
[141] | |||
| Compound Name |
(S)-2-((3As,6S,6aR)-4-Benzothiazol-2-yl-6-methyl-5-oxo-hexahydro-pyrrolo[3,2-b]pyrrole-1-carbonyl)-pyrrolidine-1-carboxylic acid (4-isopropyl-phenyl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL344656; BDBM50133952
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[141] | |||
| Compound Name |
Chembl4211986
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
ZINC9463364; BDBM50459536; AKOS001219290; MCULE-4052888396
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[13] | |||
| Compound Name |
(13Z)-20-Amino-22-methyl-6-(pyrazol-1-ylmethyl)-9,17-dioxa-1,21,25,29-tetrazatetracyclo[25.2.1.03,8.018,23]triaconta-3(8),4,6,13,18,20,22,27(30),28-nonaen-26-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3883461; BDBM50210073
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[139] | |||
| Compound Name |
2-[2-[(3-Carbamoylphenyl)carbamoyl]-4-(methylamino)phenyl]-5-(2-methylpropylcarbamoyl)benzoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL375051; BDBM50197326; 2''-(3-carbamoyl-phenylcarbamoyl)-4-isobutylcarbamoyl-4''-methylamino-biphenyl-2-carboxylic acid
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[137] | |||
| Compound Name |
Chembl4212332
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
SCHEMBL20037270; BDBM50459511; ZINC10622021; AKOS008062054; MCULE-9531505500; [2-[(3,5-dimethyl-1-phenylpyrazol-4-yl)amino]-2-oxoethyl] 2-(2-methylindol-1-yl)acetate
Click to Show/Hide
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||||
| Activity |
IC50 > 200000 nM
|
[13] | |||
| Compound Name |
Chembl4213790
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL914066; BDBM50457931; 2-(2,6-difluorophenyl)-7-nitro-3,1-benzoxazin-4-one; 2-(2,6-Difluorophenyl)-7-nitro-4H-3,1-benzoxazine-4-one; 2-(2,6-difluoro-phenyl)-7-nitro-benzo[d][1,3]oxazin-4-one; 7-Nitro-2-(2,6-difluoro-phenyl)-benzo[d][1,3]oxazin-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[100] | |||
| Compound Name |
(8e)-3-Amino-1-Methyl-15-[(1h-Pyrazol-1-Yl)methyl]-7,10,11,12,24,25-Hexahydro-6h,18h,23h-19,22-(Metheno)pyrido[4,3-J][1,9,13,17,18]benzodioxatriazacyclohenicosin-23-One
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3884851; BDBM50210127; GBT
Click to Show/Hide
|
||||
| Activity |
IC50 > 200000 nM
|
[139] | |||
| Compound Name |
3-[4-[(4-Carbamimidoylphenyl)sulfonylamino]butanoylamino]benzoic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159300
Click to Show/Hide
|
||||
| Activity |
Ki = 201000 nM
|
[26] | |||
| Compound Name |
3-Hydroxy-4-methoxy-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL303970; BDBM50115898
Click to Show/Hide
|
||||
| Activity |
Ki = 205000 nM
|
[123] | |||
| Compound Name |
N-[3-(4-Aminothieno[3,2-c]pyridin-2-yl)-1-(4-methylpiperidin-1-yl)-1-oxopropan-2-yl]naphthalene-2-sulfonamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL315892; BDBM50081816
Click to Show/Hide
|
||||
| Activity |
IC50 = 209000 nM
|
[142] | |||
| Compound Name |
1beta,5beta-Bis[4-[3-(1-amidino-4-piperidinyl)propionyl]piperazinocarbonyloxy]cyclooctane
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL76424; SCHEMBL7420671; BDBM50093186
Click to Show/Hide
|
||||
| Activity |
Ki = 213000 nM
|
[119] | |||
| Compound Name |
N-[(R)-4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-(2-oxo-piperazin-1-yl)-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL351052; BDBM50124980
Click to Show/Hide
|
||||
| Activity |
IC50 = 220000 nM
|
[143] | |||
| Compound Name |
4-[(3-Methoxyphenyl)methylsulfamoyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159371
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|
||||
| Activity |
Ki = 223000 nM
|
[26] | |||
| Compound Name |
Chembl4217769
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455312
Click to Show/Hide
|
||||
| Activity |
IC50 = 229000 nM
|
[127] | |||
| Compound Name |
(1-{[(4-Carbamimidoyl-benzylcarbamoyl)-methyl]-carbamoyl}-2-hydroxy-ethyl)-carbamic acid benzyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL422533; BDBM50110005; Cbz-D-Ser-Gly-(4-Amidinobenzyl)NH2
Click to Show/Hide
|
||||
| Activity |
Ki = 230000 nM
|
[67] | |||
| Compound Name |
3-(5-Carbamimidoyl-benzofuran-2-yl)-2-[4-((S)-pyrrolidin-3-yloxy)-phenyl]-propionic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL280157; BDBM50041226; 3-(5-carbamimidoyl-1-benzofuran-2-yl)-2-[4-[(3S)-pyrrolidin-3-yl]oxyphenyl]propanoic acid; 4-[[(3S)-Pyrrolidin-3beta-yl]oxy]-alpha-[(5-amidinobenzofuran-2-yl)methyl]benzeneacetic acid
Click to Show/Hide
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||||
| Activity |
IC50 = 230000 nM
|
[107] | |||
| Compound Name |
1,9-Di{4-[5-amino(imino)methylbenzo[b]furan-2-ylcarbonyl]hexahydro-1-pyrazinyl}-1,9-nonanedione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL113452; BDBM50083552; 2,2'-[1,9-Dioxononane-1,9-diylbis(piperazine-4,1-diylcarbonyl)]bis(benzofuran-5-carboxamidine)
Click to Show/Hide
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||||
| Activity |
Ki = 230000 nM
|
[25] | |||
| Compound Name |
4-(N-Benzylsulfamoyl)Benzamidinium Chloride
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159369
Click to Show/Hide
|
||||
| Activity |
Ki = 230000 nM
|
[26] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[4-(Diaminomethylideneamino)butanoylamino]-3-(4-nitrophenyl)propanoyl]amino]-3-hydroxybutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL110564
Click to Show/Hide
|
||||
| Activity |
IC50 = 230000 nM
|
[144] | |||
| Compound Name |
N-[3-(2-Amino-ethoxy)-5-methyl-phenyl]-benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42069; SCHEMBL7371793; BDBM50070627; N-[3-(2-aminoethoxy)-5-methylphenyl]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
Ki = 240000 nM
|
[133] | |||
| Compound Name |
n-(4-Carbamimidoyl-3-choro-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL62897; N-(4-carbamimidoyl-3-chlorophenyl)-2-hydroxy-3-iodo-5-methylbenzamide; BDBM14159; APC-11421; DB06857; Q27095762; N-(3-Chloro-4-amidinophenyl)-2-hydroxy-3-iodo-5-methylbenzamide; N-{4-[amino(imino)methyl]-3-chlorophenyl}-2-hydroxy-3-iodo-5-methylbenzamide
Click to Show/Hide
|
||||
| Activity |
Ki = 245000 nM
|
[123] | |||
| Compound Name |
3-[(4-Methoxyphenyl)methylsulfamoyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159378
Click to Show/Hide
|
||||
| Activity |
Ki = 245000 nM
|
[26] | |||
| Compound Name |
Dihydrospumigin M
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4173128; BDBM50277987
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[145] | |||
| Compound Name |
Dihydrospumigin N
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4176114; BDBM50277986
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[145] | |||
| Compound Name |
Acetic acid;(2S)-N-[(4-carbamimidoylphenyl)methyl]-1-ethylpyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4063628; BDBM50259726
Click to Show/Hide
|
||||
| Activity |
Ki = 250000 nM
|
[45] | |||
| Compound Name |
2-[(4-Carbamimidoylphenyl)sulfonylamino]-N-(3,4-dimethoxyphenyl)acetamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159381
Click to Show/Hide
|
||||
| Activity |
Ki = 250000 nM
|
[26] | |||
| Compound Name |
alpha-(Benzyloxycarbonylamino)-4-guanidinobenzylphosphonic acid diphenyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL379807; CHEMBL1184949; SCHEMBL17126717; BDBM50184643
Click to Show/Hide
|
||||
| Activity |
IC50 = 250000 nM
|
[54] | |||
| Compound Name |
1beta,5beta-Bis[4-(4-guanidinophenylacetyl)piperazinocarbonyloxy]cyclooctane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL309830; SCHEMBL7422920; BDBM50093173
Click to Show/Hide
|
||||
| Activity |
Ki = 255000 nM
|
[119] | |||
| Compound Name |
(2S)-2-[[(2S,3S)-2-[[(2S,3S)-2-[[(2S)-6-Amino-2-[(2,5-dihydroxybenzoyl)amino]hexanoyl]amino]-3-methylpentanoyl]amino]-3-methylpentanoyl]amino]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372678
Click to Show/Hide
|
||||
| Activity |
IC50 = 257000 nM
|
[24] | |||
| Compound Name |
Chembl297329
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372741; BDBM50070714
Click to Show/Hide
|
||||
| Activity |
IC50 = 262000 nM
|
[24] | |||
| Compound Name |
2-(3,4-Dihydroxyphenyl)-5-[[4-[[2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4-oxochromen-5-yl]oxymethyl]phenyl]methoxy]-3,7-dihydroxychromen-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4069227; BDBM50260050
Click to Show/Hide
|
||||
| Activity |
IC50 = 267000 nM
|
[132] | |||
| Compound Name |
[5-[4-[[4-(Diaminomethylideneamino)phenyl]methylcarbamoyl]piperazine-1-carbonyl]oxycyclooctyl] 4-[2-(1-methylpiperidin-4-yl)ethylcarbamoyl]piperazine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77361; BDBM50093149
Click to Show/Hide
|
||||
| Activity |
Ki = 269000 nM
|
[119] | |||
| Compound Name |
(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-6-Amino-2-[(2,5-dihydroxybenzoyl)amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylpentanoyl]amino]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372700; BDBM50215734
Click to Show/Hide
|
||||
| Activity |
IC50 = 273000 nM
|
[24] | |||
| Compound Name |
[5-[4-[[4-(Diaminomethylideneamino)phenyl]methylcarbamoyl]piperazine-1-carbonyl]oxycyclooctyl] 4-[(4-aminocyclohexyl)methylcarbamoyl]piperazine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL77182; CHEMBL308763; BDBM50093176; BDBM50093193
Click to Show/Hide
|
||||
| Activity |
Ki = 274000 nM
|
[119] | |||
| Compound Name |
(2R,4S)-1-[(2S)-5-(Diaminomethylamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]pentanoyl]-4-methylpiperidine-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2093100; BDBM50454549
Click to Show/Hide
|
||||
| Activity |
Ki = 280000 nM
|
[146] | |||
| Compound Name |
2-Aminoethyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL205366; BDBM50180536
Click to Show/Hide
|
||||
| Activity |
IC50 = 284000 nM
|
[116] | |||
| Compound Name |
[4-[[3-[1,3-Dioxo-5-[(4-sulfooxyphenyl)carbamoyl]isoindol-2-yl]benzoyl]amino]phenyl] hydrogen sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2312001; BDBM50423880
Click to Show/Hide
|
||||
| Activity |
IC50 = 286000 nM
|
[62] | |||
| Compound Name |
(2S)-1-[(2R)-2-(Benzylsulfonylamino)-3-cyclohexylpropanoyl]-N-(5,6,7,8-tetrahydroquinazolin-6-ylmethyl)pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL165196; BDBM50124070
Click to Show/Hide
|
||||
| Activity |
Ki = 289000 nM
|
[147] | |||
| Compound Name |
Chembl46763
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372742; BDBM50070715
Click to Show/Hide
|
||||
| Activity |
IC50 = 294000 nM
|
[24] | |||
| Compound Name |
Chembl295218
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372692; BDBM50070721
Click to Show/Hide
|
||||
| Activity |
IC50 = 298000 nM
|
[24] | |||
| Compound Name |
(S)-2-{(S)-2-[(S)-2-(4-Amino-butyrylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-phenyl-propionic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL302565; BDBM50039015
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[42] | |||
| Compound Name |
{1-[2-(4-Carbamimidoyl-benzylcarbamoyl)-indan-2-ylcarbamoyl]-1-methyl-ethylamino}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL215801; BDBM50193226
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[82] | |||
| Compound Name |
{(R)-1-[2-(4-Carbamimidoyl-benzylcarbamoyl)-indan-2-ylcarbamoyl]-2-methyl-propylamino}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL426333; SCHEMBL5395593; BDBM50193240
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[82] | |||
| Compound Name |
5-Chloropyridin-3-yl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL337718; SCHEMBL7679148; BDBM50180539; (5-chloropyridin-3-yl) 6-(chloromethyl)-2-oxochromene-3-carboxylate; 6-(Chloromethyl)-2-oxo-2H-1-benzopyran-3-carboxylic acid 5-chloro-3-pyridyl ester; 6-Chloromethyl-2-oxo-2H-chromene-3-carboxylic acid 5-chloro-pyridin-3-yl ester
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[116] | |||
| Compound Name |
{(R)-1-[2-(4-Carbamimidoyl-benzylcarbamoyl)-2,3-dihydro-1H-phenalen-2-ylcarbamoyl]-2-methyl-propylamino}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL215357; BDBM50193229
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[82] | |||
| Compound Name |
Piperidin-4-yl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL380008; BDBM50180532
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[116] | |||
| Compound Name |
3-Guanidinophenyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL204528; BDBM50180533
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[116] | |||
| Compound Name |
Chembl4211424
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455310
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[127] | |||
| Compound Name |
4-[[(3R)-5-[2-[(4-Carbamimidoylphenyl)methylamino]-2-oxoethyl]-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl]amino]-4-oxobutanoic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL557679
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[83] | |||
| Compound Name |
{(R)-1-[6-(4-Carbamimidoyl-benzylcarbamoyl)-6,7-dihydro-5H-[1]pyrindin-6-ylcarbamoyl]-2-methyl-propylamino}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL215870; BDBM50193235
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[82] | |||
| Compound Name |
3-Guanidinopropyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL205429; BDBM50180544
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[116] | |||
| Compound Name |
4-Aminocyclohexyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL377702; BDBM50180535
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[116] | |||
| Compound Name |
3-Aminopropyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL205396; BDBM50180543
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[116] | |||
| Compound Name |
Chembl44935
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372675; BDBM50070772
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[24] | |||
| Compound Name |
2-(Naphthalene-2-sulfonylamino)-N-[(S)-1-(piperidine-1-carbonyl)-3-(pyridin-4-ylamino)-propyl]-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL23300; BDBM50289378
Click to Show/Hide
|
||||
| Activity |
Ki = 300000 nM
|
[122] | |||
| Compound Name |
{(R)-1-[2-(4-Carbamimidoyl-benzylcarbamoyl)-2,3-dihydro-1H-cyclopenta[b]naphthalen-2-ylcarbamoyl]-2-methyl-propylamino}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL213774; BDBM50193239
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[82] | |||
| Compound Name |
2-{[(1R)-1-[(2-{[(4-Carbamimidoylphenyl)methyl]carbamoyl}-2,3-dihydro-1H-inden-2-yl)carbamoyl]propyl]amino}acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL212971; BDBM50193222
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[82] | |||
| Compound Name |
Chembl4209061
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455304
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[127] | |||
| Compound Name |
{(R)-1-[2-(4-Carbamimidoyl-benzylcarbamoyl)-indan-2-ylcarbamoyl]-2,2-dimethyl-propylamino}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL213120; BDBM50193238
Click to Show/Hide
|
||||
| Activity |
IC50 = 300000 nM
|
[82] | |||
| Compound Name |
2-[[(2R)-1-[[9-[(4-Carbamimidoylphenyl)methylcarbamoyl]-9-tricyclo[9.4.0.02,7]pentadeca-1(15),2,4,6,11,13-hexaenyl]amino]-3-methyl-1-oxobutan-2-yl]amino]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL424882; BDBM50193225
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[82] | |||
| Compound Name |
Sodium;[3-ethoxycarbonyl-2-[[3-ethoxycarbonyl-2-[(3-ethoxycarbonyl-6-methoxy-2-methyl-1-benzofuran-5-yl)oxymethyl]-6-methoxy-1-benzofuran-5-yl]oxymethyl]-1H-indol-5-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3359904
Click to Show/Hide
|
||||
| Activity |
IC50 = 304000 nM
|
[129] | |||
| Compound Name |
3-Hydroxy-4-iodo-anthracene-2-carboxylic acid (6-guanidino-pyridin-3-yl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL59936; BDBM50115899
Click to Show/Hide
|
||||
| Activity |
Ki = 310000 nM
|
[123] | |||
| Compound Name |
N-(4-Guanidino-phenyl)-2-hydroxy-5-nitro-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64463; BDBM50115885
Click to Show/Hide
|
||||
| Activity |
Ki = 315000 nM
|
[123] | |||
| Compound Name |
Chembl297802
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372693; BDBM50070775
Click to Show/Hide
|
||||
| Activity |
IC50 = 318000 nM
|
[24] | |||
| Compound Name |
N-[2-(3-Amidinophenoxy)ethyl]-2'-sulfamoylbiphenyl-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL432306; BDBM50114455; 2''-Sulfamoyl-biphenyl-4-carboxylic acid [2-(3-carbamimidoyl-phenoxy)-ethyl]-amide
Click to Show/Hide
|
||||
| Activity |
IC50 = 321000 nM
|
[148] | |||
| Compound Name |
(S)-1-Butyryl-N-(3-chlorobenzyl)pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL599468; BDBM50307839; N-(3-Chlorobenzyl)-1-butyryl-L-prolinamide
Click to Show/Hide
|
||||
| Activity |
Ki = 322000 nM
|
[38] | |||
| Compound Name |
3-Amino-N-{3-[(S)-2-[4-(2-amino-ethyl)-piperidin-1-yl]-1-(4-aminomethyl-benzyl)-2-oxo-ethylsulfamoyl]-phenyl}-propionamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL462253; BDBM50253981
Click to Show/Hide
|
||||
| Activity |
Ki = 325000 nM
|
[149] | |||
| Compound Name |
((S)-4-{[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-methyl}-3-oxo-1-phenylmethanesulfonyl-piperazin-2-yl)-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL163466; SCHEMBL7383509; BDBM50125032
Click to Show/Hide
|
||||
| Activity |
IC50 = 325000 nM
|
[48] | |||
| Compound Name |
Sodium;[2-[(2-methyl-1,3-benzothiazol-6-yl)oxymethyl]-1,3-benzothiazol-6-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3359899
Click to Show/Hide
|
||||
| Activity |
IC50 = 327000 nM
|
[129] | |||
| Compound Name |
Sodium;[2-[(2-benzyl-3-ethoxycarbonyl-6-methoxy-1-benzofuran-5-yl)oxymethyl]-3-ethoxycarbonyl-1H-indol-5-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3359902
Click to Show/Hide
|
||||
| Activity |
IC50 = 327000 nM
|
[129] | |||
| Compound Name |
4-Bromo-3-hydroxy-anthracene-2-carboxylic acid (6-guanidino-pyridin-3-yl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64653; BDBM50115889
Click to Show/Hide
|
||||
| Activity |
Ki = 330000 nM
|
[123] | |||
| Compound Name |
(S)-2-{(S)-2-[(S)-2-(7-Amino-heptanoylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-3-phenyl-propionic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL66746; BDBM50039019
Click to Show/Hide
|
||||
| Activity |
IC50 = 330000 nM
|
[42] | |||
| Compound Name |
(S)-N-(3-Chlorobenzyl)-1-propionylpyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL608724; BDBM50307838
Click to Show/Hide
|
||||
| Activity |
Ki = 330000 nM
|
[32] | |||
| Compound Name |
6-Amino-N-[(3S,7E,9S,12R,16S,19S)-16-[[3-(aminomethyl)phenyl]methyl]-12-[(2S)-butan-2-yl]-9-[(4-hydroxyphenyl)methyl]-2,6,11,14,18-pentaoxo-1,5,10,13,17-pentazabicyclo[17.3.0]docos-7-en-3-yl]hexanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927450; BDBM50359553
Click to Show/Hide
|
||||
| Activity |
Ki = 330000 nM
|
[150] | |||
| Compound Name |
1-(4-Chlorophenyl)-1H-tetrazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1-(4-Chloro-phenyl)-1H-tetrazole; 1-(4-chlorophenyl)-1H-1,2,3,4-tetrazole; 1-(4-chlorophenyl)tetrazole; 1H-Tetrazole, 1-(4-chlorophenyl)-; CHEMBL440394; 1H-Tetrazole,1-(4-chlorophenyl)-; MLS000073198; SCHEMBL10738426; BDBM12582; chlorophenyl-tetrazole compound 1; CTK4F4985; DTXSID20296827; HMS2411A21; ZINC114300; CCG-17721; NSC111893; STK379273; AKOS000573429; MCULE-9962843658; NSC-111893; SMR000010731; ST025322; 1-(4-chlorophenyl)-1,2,3,4-tetraazole; 1-(4-Chlorophenyl)-1,2,3,4-tetrazole; BB 0238187; EU-0006928; SR-01000452296; SR-01000452296-1; Q27458614; Z57165774
Click to Show/Hide
|
||||
| Activity |
IC50 = 330000 nM
|
[151] | |||
| Compound Name |
(S)-2-[(S)-2-((S)-2-Amino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionic acid methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL293873; BDBM50039013
Click to Show/Hide
|
||||
| Activity |
IC50 > 333000 nM
|
[42] | |||
| Compound Name |
(R)-5-[(S)-2-(4-Guanidino-butylcarbamoyl)-pyrrolidin-1-yl]-4-(naphthalene-2-sulfonylamino)-5-oxo-pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL144992; SCHEMBL7339840; BDBM50107464; N-(2-Naphthylsulfonyl)-D-Glu-L-Pro-(4-guanidinobutyl)NH2
Click to Show/Hide
|
||||
| Activity |
IC50 > 333000 nM
|
[118] | |||
| Compound Name |
2-Phenyl-1H-benzimidazole-5-carboxamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL96917; SCHEMBL14599542; BDBM50100891; ZINC12354847; 2-Phenyl-1H-benzoimidazole-5-carboxamidine; 2-Phenyl-3H-benzoimidazole-5-carboxamidine; 2-phenyl-3H-benzimidazole-5-carboximidamide
Click to Show/Hide
|
||||
| Activity |
Ki = 340000 nM
|
[61] | |||
| Compound Name |
Chembl47797
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372745; BDBM50070736
Click to Show/Hide
|
||||
| Activity |
IC50 = 341000 nM
|
[24] | |||
| Compound Name |
N-[1-(1-Amino-isoquinolin-6-ylmethyl)-2-oxo-2-piperidin-1-yl-ethyl]-2-(toluene-4-sulfonylamino)-acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL162185; BDBM50075825; 1-[2-(N-Tosylglycylamino)-3-(1-amino-6-isoquinolinyl)propionyl]piperidine
Click to Show/Hide
|
||||
| Activity |
IC50 = 357000 nM
|
[35] | |||
| Compound Name |
1,3-Bis[4-(4-guanidinobenzylcarbamoyl)piperazinocarbonyloxymethyl]adamantane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL78283; BDBM50093196
Click to Show/Hide
|
||||
| Activity |
Ki = 363000 nM
|
[119] | |||
| Compound Name |
Disodium;[3-ethoxycarbonyl-2-[(3-ethoxycarbonyl-6-methoxy-2-methyl-1-benzofuran-5-yl)oxymethyl]-5-sulfonatooxy-1-benzofuran-6-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812020
Click to Show/Hide
|
||||
| Activity |
IC50 = 363078.05 nM
|
[50] | |||
| Compound Name |
(2S)-N-[(3-Chlorophenyl)methyl]-1-(2-cyclohexylethyl)pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3422993; BDBM50082628
Click to Show/Hide
|
||||
| Activity |
Ki = 370000 nM
|
[32] | |||
| Compound Name |
(2S)-1-[(2R)-2-Amino-3-methylbutyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3422998; BDBM50082527
Click to Show/Hide
|
||||
| Activity |
Ki = 370000 nM
|
[32] | |||
| Compound Name |
Sodium;[3-carboxy-2-[(3-carboxy-6-methoxy-2-methyl-1-benzofuran-5-yl)oxymethyl]-6-methoxy-1-benzofuran-5-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812018
Click to Show/Hide
|
||||
| Activity |
IC50 = 371535.23 nM
|
[50] | |||
| Compound Name |
Sodium;[6-methoxy-3-(2-methoxyethoxycarbonyl)-2-[[6-methoxy-3-(2-methoxyethoxycarbonyl)-2-methyl-1-benzofuran-5-yl]oxymethyl]-1-benzofuran-5-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812013
Click to Show/Hide
|
||||
| Activity |
IC50 = 375000 nM
|
[50] | |||
| Compound Name |
Chembl48835
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372691; BDBM50070682
Click to Show/Hide
|
||||
| Activity |
IC50 = 378000 nM
|
[24] | |||
| Compound Name |
1,4-Bis[[2-oxo-2-(1-amidino-4-piperidinylmethylamino)ethyl]carbamoyloxymethyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL297408; BDBM50101014
Click to Show/Hide
|
||||
| Activity |
Ki = 386000 nM
|
[28] | |||
| Compound Name |
Chembl46428
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372734; BDBM50070727
Click to Show/Hide
|
||||
| Activity |
IC50 = 394000 nM
|
[24] | |||
| Compound Name |
3-Benzylbenzamidine
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3247185; 3-benzylbenzenecarboximidamide; BDBM50010249; ZINC39191567
Click to Show/Hide
|
||||
| Activity |
Ki = 398107.17 nM
|
[78] | |||
| Compound Name |
3-(6-Carbamimidoyl-benzofuran-2-yl)-2-{4-[(S)-1-(1-imino-ethyl)-pyrrolidin-3-yloxy]-phenyl}-propionic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL277240; BDBM50041223
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[107] | |||
| Compound Name |
(2S)-N-[(3-Chlorophenyl)methyl]-1-(4-methylpentyl)pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3422992; BDBM50082629
Click to Show/Hide
|
||||
| Activity |
Ki = 400000 nM
|
[32] | |||
| Compound Name |
((S)-5-Amino-1-{[(1-formyl-4-guanidino-butylcarbamoyl)-methyl]-carbamoyl}-pentyl)-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372430; BDBM50083997; (2S)-2-[(Boc-D-Har-Gly-)Amino]-5-guanidinopentanal
Click to Show/Hide
|
||||
| Activity |
IC50 = 400000 nM
|
[14] | |||
| Compound Name |
(2S)-2-Acetamido-N-[(2S)-1-[[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]-3-phenylpropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1797523; BDBM50347169
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[152] | |||
| Compound Name |
Methyl (2S,4S)-4-amino-2-[[(2S,4S)-4-amino-2-[3-[(1R,3R)-3-[[(2S,4S)-4-amino-2-[[(2S,4S)-4-amino-5-(1H-indol-3-yl)-3-oxo-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-(1H-indol-3-yl)-3-oxopentanoyl]amino]-2-oxocyclohexyl]propanoylamino]-5-(1H-indol-3-yl)-3-oxopentanoyl]amino]-5-(4-hydroxyphenyl)-3-oxopentanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL265127; BDBM50292271
Click to Show/Hide
|
||||
| Activity |
IC50 > 400000 nM
|
[153] | |||
| Compound Name |
Chembl45112
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372750; BDBM50070763
Click to Show/Hide
|
||||
| Activity |
IC50 = 406000 nM
|
[24] | |||
| Compound Name |
1,4,7-Tribenzyl-1,4,7-triazacyclononane
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
1,4,7-tribenzyl-1,4,7-triazonane; CHEMBL445110; 1,4,7-Tribenzyl-[1,4,7]triazonane; 1H-1,4,7-Triazonine, octahydro-1,4,7-tris(phenylmethyl)-; ACMC-20mrft; SCHEMBL1041303; CTK0C2393; DTXSID10461825; BDBM50071642; MFCD26391018; SY253702
Click to Show/Hide
|
||||
| Activity |
Ki = 410000 nM
|
[134] | |||
| Compound Name |
Chembl295541
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372714; BDBM50070731
Click to Show/Hide
|
||||
| Activity |
IC50 = 422000 nM
|
[24] | |||
| Compound Name |
1,4-Bis[[2-oxo-2-[2-(1-amidino-4-piperidinyl)ethylamino]ethyl]carbamoyloxymethyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL406192; BDBM50101013
Click to Show/Hide
|
||||
| Activity |
Ki = 423000 nM
|
[28] | |||
| Compound Name |
Sodium;[3-ethoxycarbonyl-2-[(3-ethoxycarbonyl-2-methyl-1H-indol-5-yl)oxymethyl]-1-[(2-methylpropan-2-yl)oxycarbonyl]indol-5-yl] sulfate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3359903
Click to Show/Hide
|
||||
| Activity |
IC50 = 425000 nM
|
[129] | |||
| Compound Name |
Chembl416280
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372730; BDBM50070743
Click to Show/Hide
|
||||
| Activity |
IC50 = 428000 nM
|
[24] | |||
| Compound Name |
(2S)-1-[(2R)-2-Aminobutyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3422997; BDBM50082529
Click to Show/Hide
|
||||
| Activity |
Ki = 430000 nM
|
[32] | |||
| Compound Name |
5-Chlorothiophene-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
5-chloro-2-thiophenecarboxamide; CHEMBL3608990; SCHEMBL92875; 5-chlorothiophene-2-carboxamid; CTK4E9253; DTXSID10409141; 2-Thiophenecarboxamide, 5-chloro-; KS-00001U1W; ZINC2753342; 7651AD; BDBM50115490; MFCD01922226; SBB087552; STK315793; AKOS000278666; MCULE-8431102003; QC-5845; FT-0680149; ST45159813; 1T-0800; J-517420; Q27460402
Click to Show/Hide
|
||||
| Activity |
Ki = 431000 nM
|
[5] | |||
| Compound Name |
[5-[4-[[4-(Diaminomethylideneamino)phenyl]methylcarbamoyl]piperazine-1-carbonyl]oxycyclooctyl] 4-[[4-(diaminomethylideneamino)phenyl]methylcarbamoyl]piperazine-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL46809; APC-1390; SCHEMBL7415218; BDBM50093142; BDBM50218667; 1beta,5beta-Bis[4-(4-guanidinobenzylcarbamoyl)piperazinocarbonyloxy]cyclooctane; 1,5-di{4-[4-amino(imino)methylaminobenzylcarbamoyl]hexahydro-1-pyrazinylcarbonyloxy}cyclooctane
Click to Show/Hide
|
||||
| Activity |
Ki = 435000 nM
|
[119] | |||
| Compound Name |
N-[2-(3-Carbamimidoyl-phenoxy)-ethyl]-4-[1-(1-imino-ethyl)-piperidin-4-yloxy]-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL51796; SCHEMBL14132194; BDBM50127496
Click to Show/Hide
|
||||
| Activity |
Ki = 440000 nM
|
[29] | |||
| Compound Name |
Chembl44650
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372653; BDBM50070706
Click to Show/Hide
|
||||
| Activity |
IC50 = 446000 nM
|
[24] | |||
| Compound Name |
Chembl47291
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372690; BDBM50070755
Click to Show/Hide
|
||||
| Activity |
IC50 = 446000 nM
|
[24] | |||
| Compound Name |
3-Hydroxy-4-iodo-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL60478; BDBM50115877
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
N-(4-Guanidino-phenyl)-2-hydroxy-5-methoxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64563; BDBM50115904
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
N-(4-Guanidino-phenyl)-2-hydroxy-4-methyl-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64308; BDBM50115884
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
4-Bromo-3-hydroxy-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL63050; BDBM50115880
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
N-(4-Guanidino-phenyl)-2-hydroxy-3-methyl-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL59690; BDBM50115900
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
3-Hydroxy-4-isopropoxy-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL304219; BDBM50115902
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
N-(4-Guanidino-phenyl)-2-hydroxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL303335; BDBM50115883; N-(4-Guanidinophenyl)-2-hydroxybenzamide
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
4-Chloro-N-(4-guanidino-phenyl)-2-hydroxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL292488; BDBM50115881
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
5-Bromo-N-(4-guanidino-phenyl)-2-hydroxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL62414; BDBM50115882
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
4-Ethoxy-N-(4-guanidino-phenyl)-2-hydroxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL63038; BDBM50115887
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
3-Hydroxy-anthracene-2-carboxylic acid (4-guanidino-phenyl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64740; BDBM50115891
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
N-(4-Guanidino-phenyl)-2-hydroxy-3-iodo-5-methyl-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64164; BDBM50115888; N-(4-Guanidinophenyl)-2-hydroxy-3-iodo-5-methylbenzamide
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
3-Chloro-N-(4-guanidino-phenyl)-2-hydroxy-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL294776; BDBM50115892
Click to Show/Hide
|
||||
| Activity |
Ki = 450000 nM
|
[123] | |||
| Compound Name |
3-Hydroxy-4-isopropoxy-anthracene-2-carboxylic acid (6-guanidino-pyridin-3-yl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL63216; BDBM50115896
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
N-(4-Guanidino-phenyl)-2-hydroxy-5-methyl-benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL64841; BDBM50115897; Benzamide,N-[4-[(aminoiminomethyl)amino]phenyl]-2-hydroxy-5-methyl-
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
2-Hydroxy-biphenyl-3-carboxylic acid (4-guanidino-phenyl)-amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL291622; BDBM50115890
Click to Show/Hide
|
||||
| Activity |
Ki > 450000 nM
|
[123] | |||
| Compound Name |
Chembl297451
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372704; BDBM50070720
Click to Show/Hide
|
||||
| Activity |
IC50 = 458000 nM
|
[24] | |||
| Compound Name |
Ethyl 2-[(2E)-2-carbamimidoylimino-6-hydroxy-1,3-benzothiazol-3-yl]acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2047998; BDBM50387180
Click to Show/Hide
|
||||
| Activity |
Ki = 481000 nM
|
[88] | |||
| Compound Name |
(S)-N-(3-Chlorobenzyl)-1-(3,3-dimethylbutanoyl)pyrrolidine-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL598416; BDBM50307841
Click to Show/Hide
|
||||
| Activity |
Ki = 484000 nM
|
[38] | |||
| Compound Name |
1,4-Bis[1,5-dioxo-5-(4-guanidinobenzylamino)pentylaminomethyl]benzene
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL79545; BDBM50093147
Click to Show/Hide
|
||||
| Activity |
Ki = 492000 nM
|
[154] | |||
| Compound Name |
{(S)-1-[(S)-2-(1-Formyl-4-guanidino-butylcarbamoyl)-pyrrolidine-1-carbonyl]-4-guanidino-butyl}-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL40765; BDBM50084008
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[14] | |||
| Compound Name |
4-[(4-Methoxyphenyl)sulfamoyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159366
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
1-(4-Benzyloxy-benzyl)-pyridinium
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL296280; BDBM50070789
Click to Show/Hide
|
||||
| Activity |
Ki > 500000 nM
|
[155] | |||
| Compound Name |
Chembl4207916
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455286
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[127] | |||
| Compound Name |
Chembl4218970
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455288
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[127] | |||
| Compound Name |
3-[(3,4-Dimethoxyphenyl)methylsulfamoyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159380
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
{(S)-1-[1-(1-Formyl-4-guanidino-butylcarbamoyl)-1-methyl-ethylcarbamoyl]-4-guanidino-butyl}-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372424; BDBM50083989; (2S)-2-[(Boc-D-Arg-Aib-)Amino]-5-guanidinopentanal
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[14] | |||
| Compound Name |
3-[[2-[(4-Carbamimidoylphenyl)sulfonylamino]acetyl]amino]benzoic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159296
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
4-[(3-Methoxyphenyl)sulfamoyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159367
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
((S)-4-Amino-1-{[(1-formyl-4-guanidino-butylcarbamoyl)-methyl]-carbamoyl}-butyl)-carbamic acid tert-butyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372433; BDBM50083991; (2S)-2-[(Boc-D-Orn-Gly-)Amino]-5-guanidinopentanal
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[14] | |||
| Compound Name |
4-(N-Phenylsulfamoyl)Benzamidinium Chloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159365
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
Chembl4212825
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455311
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[127] | |||
| Compound Name |
Chembl4202894
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50455306
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[127] | |||
| Compound Name |
4-[(4-Methoxyphenyl)methylsulfamoyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159370
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
4-[(3,4-Dimethoxyphenyl)sulfamoyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159368
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
4-[3-[(4-Carbamimidoylphenyl)sulfonylamino]propanoylamino]benzoic acid;2,2,2-trifluoroacetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159297
Click to Show/Hide
|
||||
| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
4-[(4-Carbamimidoylphenyl)sulfonylamino]-N-(3,4-dimethoxyphenyl)butanamide;hydrochloride
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159384
Click to Show/Hide
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| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
4-[[2-[(4-Carbamimidoylphenyl)sulfonylamino]acetyl]amino]benzoic acid;2,2,2-trifluoroacetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159295
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| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
N-[(R)-4-Guanidino-1-(thiazole-2-carbonyl)-butyl]-2-(4-phenylmethanesulfonyl-piperazin-1-yl)-acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL351982; BDBM50125005
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| Activity |
IC50 > 500000 nM
|
[143] | |||
| Compound Name |
4-[(4-Carbamimidoylphenyl)sulfonylamino]-N-[(3,4-dimethoxyphenyl)methyl]butanamide;hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159386
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| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
Chembl4207245
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455301
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| Activity |
IC50 > 500000 nM
|
[127] | |||
| Compound Name |
3-[3-[(4-Carbamimidoylphenyl)sulfonylamino]propanoylamino]benzoic acid;2,2,2-trifluoroacetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159298
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| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
Chembl4204101
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455305
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| Activity |
IC50 > 500000 nM
|
[127] | |||
| Compound Name |
Chembl4215768
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455300
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| Activity |
IC50 > 500000 nM
|
[127] | |||
| Compound Name |
Chembl4203558
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Investigative | Compound Info | ||
| Synonyms |
BDBM50455299
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| Activity |
IC50 > 500000 nM
|
[127] | |||
| Compound Name |
4-(2-Hydroxyethylamino)-pyridine
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
2-(pyridin-4-ylamino)ethanol; 2-[(pyridin-4-yl)amino]ethan-1-ol; CHEMBL24479; Ethanol,2-(4-pyridinylamino)-; MFCD08437502; 2-(pyridin-4-ylamino)ethan-1-ol; SCHEMBL714498; 2-(Pyridin-4-ylamino)-ethanol; 4-(2-hydroxyethylamino)pyridine; 2-(N-(4-pyridyl)amino)ethanol; CTK4E0898; DTXSID50590466; Ethanol, 2-(4-pyridinylamino)-; 4-((2-Hydroxyethyl)amino)pyridine; BDBM50289380; ZINC15443514; AKOS009227756; NE31100; DB-017135; FT-0749067; EN300-66163; A803703; Z1741967608
Click to Show/Hide
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| Activity |
Ki > 500000 nM
|
[122] | |||
| Compound Name |
{(S)-1-[2-(1-Formyl-4-guanidino-butylcarbamoyl)-ethylcarbamoyl]-4-guanidino-butyl}-carbamic acid tert-butyl ester
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL41722; BDBM50084004
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| Activity |
IC50 > 500000 nM
|
[14] | |||
| Compound Name |
(3R)-2-[2-(4-Chlorophenyl)acetyl]-N-[4-(3-oxomorpholin-4-yl)phenyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2040983; BDBM50386271
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| Activity |
IC50 > 500000 nM
|
[156] | |||
| Compound Name |
4-[(3,4-Dimethoxyphenyl)methylsulfamoyl]benzenecarboximidamide;hydrochloride
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2159372
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| Activity |
IC50 > 500000 nM
|
[26] | |||
| Compound Name |
Sodium;[3-ethoxycarbonyl-6-(4-methoxybenzoyl)oxy-2-methyl-1-benzofuran-5-yl] sulfate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812005
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| Activity |
IC50 = 501187.23 nM
|
[50] | |||
| Compound Name |
Chembl47466
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372679; BDBM50070746
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| Activity |
IC50 = 507000 nM
|
[24] | |||
| Compound Name |
Chembl45045
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372752; BDBM50070722
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| Activity |
IC50 = 507000 nM
|
[24] | |||
| Compound Name |
(2S)-1-[(2R)-2-Aminopropyl]-N-[(3-chlorophenyl)methyl]pyrrolidine-2-carboxamide;hydrochloride
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3422996; BDBM50082531
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| Activity |
Ki = 512000 nM
|
[32] | |||
| Compound Name |
(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-N-[(1R,2S)-3-cyclohexyl-1-hydroxy-1-(1,3-thiazol-2-yl)propan-2-yl]-4-methylpentanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL67412; BDBM50039009
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| Activity |
IC50 > 530000 nM
|
[42] | |||
| Compound Name |
1beta,5beta-Bis[4-[3-(4-guanidinophenyl)propionyl]piperazinocarbonyloxy]cyclooctane
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL306622; SCHEMBL7426287; BDBM50093166
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||||
| Activity |
Ki = 537000 nM
|
[119] | |||
| Compound Name |
4-[5-Carbamimidoyl-2-(2-carboxy-2-oxo-ethyl)-phenoxy]-3-{4-[1-(1-imino-ethyl)-piperidin-4-yloxy]-benzoylamino}-butyric acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL55237; SCHEMBL14131890; BDBM50127492
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||||
| Activity |
Ki = 540000 nM
|
[29] | |||
| Compound Name |
Chembl47136
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372671; BDBM50070778
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||||
| Activity |
IC50 = 546000 nM
|
[24] | |||
| Compound Name |
(2S)-N-[(3-Chlorophenyl)methyl]-1-(3-phenylpropyl)pyrrolidine-2-carboxamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3422994; BDBM50082588
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| Activity |
Ki = 550000 nM
|
[32] | |||
| Compound Name |
Benzyl N-[(2R)-1-[[(2S)-1-[[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1797527; BDBM50347173
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| Activity |
IC50 = 560000 nM
|
[152] | |||
| Compound Name |
[4-(6-Chloro-naphthalene-2-sulfonyl)-piperazin-1-yl]-(5-methyl-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridin-2-yl)-methanone
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL100732; SCHEMBL12589570; BDBM50146534
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| Activity |
IC50 = 560000 nM
|
[157] | |||
| Compound Name |
[5-[4-[[4-[(E)-N'-Methoxycarbonylcarbamimidoyl]phenyl]methylcarbamoyl]piperazine-1-carbonyl]oxycyclooctyl] 4-(2-piperidin-4-ylethylcarbamoyl)piperazine-1-carboxylate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL42364; BDBM50101020
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| Activity |
Ki = 561000 nM
|
[28] | |||
| Compound Name |
(2S)-2-[[(2S)-2-(Benzylsulfonylamino)-3-phenylpropanoyl]amino]-N-[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]-4-methylpentanamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1797521; BDBM50347167
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||||
| Activity |
IC50 > 580000 nM
|
[152] | |||
| Compound Name |
(2S)-N-[(3-Chlorophenyl)methyl]-1-(3-methylbutyl)pyrrolidine-2-carboxamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3422991; BDBM50082630
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||||
| Activity |
Ki = 580000 nM
|
[32] | |||
| Compound Name |
1-(4-Benzyloxy-benzyl)-piperidin-4-ylamine
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL47349; BDBM50070794
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||||
| Activity |
Ki = 581000 nM
|
[155] | |||
| Compound Name |
Chembl295809
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372701; BDBM50070740
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||||
| Activity |
IC50 = 582000 nM
|
[24] | |||
| Compound Name |
(2S)-2-[[(2S)-2-(Benzylsulfonylamino)-3-phenylpropanoyl]amino]-N-[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]-3-phenylpropanamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1797524; BDBM50347170
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||||
| Activity |
IC50 > 590000 nM
|
[152] | |||
| Compound Name |
Chembl44386
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372753; BDBM50070739
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||||
| Activity |
IC50 = 593000 nM
|
[24] | |||
| Compound Name |
3-(7-Carbamimidoyl-naphthalen-2-yl)-2-[4-((S)-pyrrolidin-3-yloxy)-phenyl]-propionic acid ethyl ester
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL277267; BDBM50041231; 4-[[(3S)-Pyrrolidin-3beta-yl]oxy]-alpha-[(7-amidino-2-naphthyl)methyl]benzeneacetic acid ethyl ester
Click to Show/Hide
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| Activity |
IC50 > 600000 nM
|
[107] | |||
| Compound Name |
Arg-pro-pro-gly-phe
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Investigative | Compound Info | ||
| Synonyms |
Bradykinin (1-5); H-Arg-Pro-PRO-Gly-Phe-OH; CHEMBL1927653; L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanine; H-ARG-PRO-PRO-GLY-PHE-OH TRIFLUOROACETATE SALT; Bradykinin Fragment 1-5; Bradykinin(1-5); Arginyl-prolyl-prolyl-glycyl-phenylalanine; 1-5-Bradykinin(9ci); Arg1-Pro2-Pro3-Gly4-Phe5; SCHEMBL8072324; DTXSID40946610; HY-P1488; BDBM50359564; MFCD00076260; ZINC71788342; AS-66956; CS-0044432; L-Phenylalanine, N-(N-(1-(1-L-arginyl-L-prolyl)-L-prolyl)glycyl)-
Click to Show/Hide
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| Activity |
IC50 = 601000 nM
|
[75] | |||
| Compound Name |
(2S)-2-[[(2R)-2-(Benzylsulfonylamino)-3-phenylpropanoyl]amino]-N-[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]-3-phenylpropanamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1797525; BDBM50347171
Click to Show/Hide
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| Activity |
IC50 > 640000 nM
|
[152] | |||
| Compound Name |
Benzyl N-[(2S)-1-[[(2S)-1-[[(3S)-7-(diaminomethylideneamino)-2-oxo-1-phenylheptan-3-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1797526; BDBM50347172
Click to Show/Hide
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||||
| Activity |
IC50 > 650000 nM
|
[152] | |||
| Compound Name |
Chembl47874
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372715; BDBM50070694
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| Activity |
IC50 = 672000 nM
|
[24] | |||
| Compound Name |
N-[(3S,7E,9S,12R,16S,19S)-16-[[3-(Aminomethyl)phenyl]methyl]-12-[(2S)-butan-2-yl]-9-[(4-hydroxyphenyl)methyl]-2,6,11,14,18-pentaoxo-1,5,10,13,17-pentazabicyclo[17.3.0]docos-7-en-3-yl]acetamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1927307; BDBM50359552
Click to Show/Hide
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| Activity |
Ki = 680000 nM
|
[150] | |||
| Compound Name |
(3R)-4-[5-Carbamimidoyl-2-(2-carboxy-2-oxoethyl)phenoxy]-3-[(1-pyridin-4-ylpiperidine-4-carbonyl)amino]butanoic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL301368; BDBM50127502
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| Activity |
Ki = 680000 nM
|
[29] | |||
| Compound Name |
Chembl40441
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372744; BDBM50070733
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| Activity |
IC50 = 680000 nM
|
[24] | |||
| Compound Name |
3-[3-(3-Benzyl-1H-indol-2-yl)-5-bromo-4-hydroxy-phenyl]-propionic acid
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL297031; BDBM50101886; 3-(3-Benzyl-1H-indole-2-yl)-4-hydroxy-5-bromobenzenepropionic acid
Click to Show/Hide
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| Activity |
Ki = 700000 nM
|
[77] | |||
| Compound Name |
4-Carbamimidoyl-N-[2-(3-carbamimidoylphenoxy)ethyl]benzamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL55363; SCHEMBL14132304; BDBM50127497; 4-Carbamimidoyl-N-[2-(3-carbamimidoyl-phenoxy)-ethyl]-benzamide
Click to Show/Hide
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| Activity |
Ki = 710000 nM
|
[29] | |||
| Compound Name |
Chembl298334
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372677; BDBM50070749
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||||
| Activity |
IC50 = 711000 nM
|
[24] | |||
| Compound Name |
Chembl432400
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2370338; BDBM50079381
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| Activity |
Ki = 720000 nM
|
[158] | |||
| Compound Name |
[5-[4-[[4-(Diaminomethylideneamino)phenyl]methylcarbamoyl]piperazine-1-carbonyl]oxycyclooctyl] 4-(3-pyridin-4-ylsulfanylpropanoyl)piperazine-1-carboxylate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL306258; BDBM50093163
Click to Show/Hide
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| Activity |
Ki = 741000 nM
|
[119] | |||
| Compound Name |
[3-[2-[(4-Methylphenyl)methyl]-3,9-dioxo-1H-chromeno[2,3-c]pyrrol-1-yl]phenyl] hydrogen sulfate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2312000; BDBM50423881
Click to Show/Hide
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||||
| Activity |
IC50 = 743000 nM
|
[62] | |||
| Compound Name |
Chembl298106
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372694; BDBM50070752
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||||
| Activity |
IC50 = 748000 nM
|
[24] | |||
| Compound Name |
Disodium;[3-ethoxycarbonyl-6-[(3-ethoxycarbonyl-6-methoxy-5-sulfonatooxy-1-benzofuran-2-yl)methoxy]-2-methyl-1-benzofuran-5-yl] sulfate
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1812019
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||||
| Activity |
IC50 = 758577.58 nM
|
[50] | |||
| Compound Name |
Schembl20625734
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1644908; BDBM34067; NSC 67931
Click to Show/Hide
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| Activity |
Ki = 786000 nM
|
[66] | |||
| Compound Name |
3-Methoxy-benzamidine
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
3-Methoxybenzimidamide; 3-methoxybenzenecarboximidamide; 3-Methoxybenzamidine; CHEMBL3247189; Benzenecarboximidamide,3-methoxy-; 5-methoxybenzamidine; 3-methoxybenzenecarboxamidine; SCHEMBL428920; CTK4F5694; DTXSID00408426; 3-methoxybenzene-1-carboximidamide; Benzenecarboximidamide, 3-methoxy-; ZINC1439405; 2322AJ; BDBM50010253; STL253522; AKOS000168993; MCULE-9305717157; NE62873; SB36205; AK137713; DA-17011; BB 0238635; FT-0716825; ST45243326; Z-8586
Click to Show/Hide
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||||
| Activity |
Ki = 794328.23 nM
|
[78] | |||
| Compound Name |
3-(Dimethylamino)benzenecarboximidamide;2,4,6-trinitrophenol
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3392242
Click to Show/Hide
|
||||
| Activity |
Ki = 794328.23 nM
|
[78] | |||
| Compound Name |
N-[2-(3-Carbamimidoyl-phenoxy)-ethyl]-benzamide
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL55364; BDBM50127505
Click to Show/Hide
|
||||
| Activity |
Ki = 800000 nM
|
[29] | |||
| Compound Name |
N-(3,5-Bis(-1-(2-carbamimidoylhydrazono)ethyl)phenyl)-4-guanidinobutanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1644915; BDBM50333191
Click to Show/Hide
|
||||
| Activity |
Ki = 800000 nM
|
[66] | |||
| Compound Name |
Chembl296297
Click to Show/Hide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2372669; BDBM50070754
Click to Show/Hide
|
||||
| Activity |
IC50 = 821000 nM
|
[24] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Syntheses of trans-5-oxo-hexahydro-pyrrolo[3,2-b]pyrroles and trans-5-oxo-hexahydro-furo[3,2-b]pyrroles (pyrrolidine trans-lactams and trans-lactones): new pharmacophores for elastase inhibition. J Med Chem. 1998 Oct 8;41(21):3919-22. | ||||
| REF 2 | Thrombin inhibitory activity of some polyphenolic compounds. Med Chem Res. 2014;23(5):2324-2337. | ||||
| REF 3 | Protease inhibitors: current status and future prospects. J Med Chem. 2000 Feb 10;43(3):305-41. | ||||
| REF 4 | Synthesis and evaluation of non-basic inhibitors of urokinase-type plasminogen activator (uPA). Bioorg Med Chem. 2012 Feb 15;20(4):1557-68. | ||||
| REF 5 | Fragment Binding Can Be Either More Enthalpy-Driven or Entropy-Driven: Crystal Structures and Residual Hydration Patterns Suggest Why. J Med Chem. 2015 Sep 10;58(17):6960-71. | ||||
| REF 6 | Novel 3-carboxamide-coumarins as potent and selective FXIIa inhibitors. J Med Chem. 2008 Jun 12;51(11):3077-80. | ||||
| REF 7 | Polymer-assisted solution-phase library synthesis and crystal structure of alpha-ketothiazoles as tissue factor VIIa inhibitors. J Med Chem. 2003 Sep 11;46(19):4043-9. | ||||
| REF 8 | Design, synthesis, and structure-activity relationship of a new class of amidinophenylurea-based factor VIIa inhibitors. Bioorg Med Chem Lett. 2003 Apr 17;13(8):1463-7. | ||||
| REF 9 | 2-(2-Hydroxy-3-alkoxyphenyl)-1H-benzimidazole-5-carboxamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors. Bioorg Med Chem Lett. 2002 Aug 5;12(15):2019-22. | ||||
| REF 10 | P4 and P1' optimization of bicycloproline P2 bearing tetrapeptidyl alpha-ketoamides as HCV protease inhibitors. Bioorg Med Chem Lett. 2004 Oct 4;14(19):5007-11. | ||||
| REF 11 | In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications ... J Med Chem. 2005 Mar 24;48(6):1984-2008. | ||||
| REF 12 | Stable and Long-Lasting, Novel Bicyclic Peptide Plasma Kallikrein Inhibitors for the Treatment of Diabetic Macular Edema. J Med Chem. 2018 Apr 12;61(7):2823-2836. | ||||
| REF 13 | Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity. J Med Chem. 2018 Oct 11;61(19):8859-8874. | ||||
| REF 14 | Design, synthesis and structure-activity relationship of a series of arginine aldehyde factor Xa inhibitors. Part 1: structures based on the (D)-Arg-Gly-Arg tripeptide sequence. Bioorg Med Chem Lett. 2000 Jan 3;10(1):13-6. | ||||
| REF 15 | Structure-based design of amidinophenylurea-derivatives for factor VIIa inhibition. Bioorg Med Chem Lett. 2004 Jul 16;14(14):3715-20. | ||||
| REF 16 | Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library. J Med Chem. 2015 Oct 22;58(20):8257-68. | ||||
| REF 17 | HLE-inhibitory alkaloids with a polyketide skeleton from the marine-derived fungus Coniothyrium cereale. J Nat Prod. 2011 Oct 28;74(10):2282-5. | ||||
| REF 18 | Optimization of O3-acyl kojic acid derivatives as potent and selective human neutrophil elastase inhibitors. J Med Chem. 2013 Dec 12;56(23):9802-6. | ||||
| REF 19 | Potent inhibitors of furin and furin-like proprotein convertases containing decarboxylated P1 arginine mimetics. J Med Chem. 2010 Feb 11;53(3):1067-75. | ||||
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