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Target General Information |
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Target ID |
T07063 |
Target Info
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Target Name |
Sodium/iodide cotransporter (SLC5A5) |
Synonyms |
Solute carrier family 5 member 5; Sodium/iodide symporter; Sodium-iodide symporter; Na+/I-symporter; Na(+)/I(-) symporter; Na(+)/I(-) cotransporter; NIS |
Target Type |
Clinical trial Target |
Gene Name |
SLC5A5 |
Biochemical Class |
Solute:sodium symporter |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-146b-5p |
miRNA Info
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miRNA Mature AC |
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Sequence |
ugagaacugaauuccauaggcug
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miRNA Species |
Homo sapiens |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay; Western Blot |
[1] |
Representative Target(s) Regulated by This miRNA |
Calgranulin D (S100A12)
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Target Info
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DNA-binding factor KBF1 (p105)
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Target Info
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References |
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REF 1 |
Inhibition of miR-146b expression increases radioiodine-sensitivity in poorly differential thyroid carcinoma via positively regulating NIS expression. Biochem Biophys Res Commun. 2015 Jul 10;462(4):314-21.
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