| References |
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| REF 1 |
Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells. Oncogene. 2010 Jan 14;29(2):201-13.
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| REF 2 |
Ubiquitination of Notch1 is regulated by MAML1-mediated p300 acetylation of Notch1. Biochem Biophys Res Commun. 2011 Dec 16;416(3-4):300-6.
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| REF 3 |
Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor. J Biol Chem. 2001 Nov 30;276(48):45031-40.
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| REF 4 |
Asparaginyl hydroxylation of the Notch ankyrin repeat domain by factor inhibiting hypoxia-inducible factor. J Biol Chem. 2007 Aug 17;282(33):24027-38.
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| REF 5 |
Down-regulation of Notch-dependent transcription by Akt in vitro. FEBS Lett. 2008 May 28;582(12):1693-9.
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| REF 6 |
Systematic interactome mapping of acute lymphoblastic leukemia cancer gene products reveals EXT-1 tumor suppressor as a Notch1 and FBWX7 common interactor. BMC Cancer. 2016 May 26;16:335.
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| REF 7 |
NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function. Mol Cell. 2012 Nov 9;48(3):445-58.
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| REF 8 |
Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jkappa or nuclear localization sequences retain the ability to associate with RBP-Jkappa and activate transcription. J Biol Chem. 1997 Apr 25;272(17):11336-43.
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| REF 9 |
Integrin-linked kinase controls Notch1 signaling by down-regulation of protein stability through Fbw7 ubiquitin ligase. Mol Cell Biol. 2007 Aug;27(15):5565-74.
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| REF 10 |
The intracellular domain of Jagged-1 interacts with Notch1 intracellular domain and promotes its degradation through Fbw7 E3 ligase. Exp Cell Res. 2011 Oct 15;317(17):2438-46.
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| REF 11 |
Characterization of a high-molecular-weight Notch complex in the nucleus of Notch(ic)-transformed RKE cells and in a human T-cell leukemia cell line. Mol Cell Biol. 2002 Jun;22(11):3927-41.
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| REF 12 |
A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters. Mol Cell Biol. 2001 Jul;21(13):4337-46.
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| REF 13 |
RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells. Exp Cell Res. 2010 Jan 15;316(2):149-57.
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| REF 14 |
Tip60 histone acetyltransferase acts as a negative regulator of Notch1 signaling by means of acetylation. Mol Cell Biol. 2007 Sep;27(18):6506-19.
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| REF 15 |
Alpha-synuclein negatively regulates Notch1 intracellular domain protein stability through promoting interaction with Fbw7. Neurosci Lett. 2015 Jul 23;600:6-11.
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| REF 16 |
The fanconi anemia core complex acts as a transcriptional co-regulator in hairy enhancer of split 1 signaling. J Biol Chem. 2009 May 15;284(20):13384-95.
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| REF 17 |
Notch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cells. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20778-83.
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| REF 18 |
Structural requirements for assembly of the CSL.intracellular Notch1.Mastermind-like 1 transcriptional activation complex. J Biol Chem. 2003 Jun 6;278(23):21232-9.
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| REF 19 |
Notch1 binds and induces degradation of Snail in hepatocellular carcinoma. BMC Biol. 2011 Nov 30;9:83.
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| REF 20 |
Non-degradative ubiquitination of the Notch1 receptor by the E3 ligase MDM2 activates the Notch signalling pathway. Biochem J. 2013 Mar 15;450(3):523-36.
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| REF 21 |
Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor. J Biol Chem. 2001 Sep 14;276(37):34371-8.
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| REF 22 |
Autophagy negatively regulates tumor cell proliferation through phosphorylation dependent degradation of the Notch1 intracellular domain. Oncotarget. 2016 Nov 29;7(48):79047-79063.
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| REF 23 |
The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia. J Exp Med. 2007 Aug 6;204(8):1825-35.
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| REF 24 |
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors. J Exp Med. 2007 Aug 6;204(8):1813-24.
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| REF 25 |
MAGEA1 interacts with FBXW7 and regulates ubiquitin ligase-mediated turnover of NICD1 in breast and ovarian cancer cells. Oncogene. 2017 Aug 31;36(35):5023-5034.
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| REF 26 |
MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nat Genet. 2000 Dec;26(4):484-9.
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| REF 27 |
Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors. Mol Cell Biol. 2002 Nov;22(21):7688-700.
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| REF 28 |
Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors. Biochem Biophys Res Commun. 2000 Sep 16;276(1):385-9.
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