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| Protein General Information |
Top |
| Full Name |
E3 ubiquitin-protein ligase DTX1 (DTX1)
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| UniProt ID |
DTX1_HUMAN
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| Gene Name |
DTX1
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| Gene ID |
1840
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| Interacting TTD Target Information |
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| Interacting Clinical trial Target(s) |
Notch-1 receptor (NOTCH1) |
Target Info
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PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
E3 ubiquitin protein ligase Itchy (ITCH) |
Target Info
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PPI Info
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[2] |
| References |
Top |
| REF 1 |
Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor. J Biol Chem. 2001 Nov 30;276(48):45031-40.
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| REF 2 |
Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains. EMBO Rep. 2006 Nov;7(11):1147-53.
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