| References |
Top |
| REF 1 |
Phosphorylation of p62 by cdk1 controls the timely transit of cells through mitosis and tumor cell proliferation. Mol Cell Biol. 2011 Jan;31(1):105-17.
|
| REF 2 |
Both p62/SQSTM1-HDAC6-dependent autophagy and the aggresome pathway mediate CDK1 degradation in human breast cancer. Sci Rep. 2017 Aug 30;7(1):10078.
|
| REF 3 |
The protein interaction landscape of the human CMGC kinase group. Cell Rep. 2013 Apr 25;3(4):1306-20.
|
| REF 4 |
Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy. Sci Signal. 2015 Apr 7;8(371):rs3.
|
| REF 5 |
Destabilization of CARP mRNAs by aloe-emodin contributes to caspase-8-mediated p53-independent apoptosis of human carcinoma cells. J Cell Biochem. 2011 Apr;112(4):1176-91.
|
| REF 6 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
|
| REF 7 |
Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes. Mol Biol Cell. 1993 Sep;4(9):897-906.
|
| REF 8 |
Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle. Science. 1992 Sep 18;257(5077):1689-94.
|
| REF 9 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440.
|
| REF 10 |
KAP: a dual specificity phosphatase that interacts with cyclin-dependent kinases. Proc Natl Acad Sci U S A. 1994 Mar 1;91(5):1731-5.
|
| REF 11 |
Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Cell Rep. 2016 Nov 22;17(9):2488-2501.
|
| REF 12 |
An essential phosphorylation-site domain of human cdc25C interacts with both 14-3-3 and cyclins. J Biol Chem. 2000 Sep 15;275(37):28849-57.
|
| REF 13 |
RGC-32 increases p34CDC2 kinase activity and entry of aortic smooth muscle cells into S-phase. J Biol Chem. 2002 Jan 4;277(1):502-8.
|
| REF 14 |
Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45. Oncogene. 1999 May 6;18(18):2892-900.
|
| REF 15 |
The cyclin box and C-terminus of cyclins A and E specify CDK activation and substrate specificity. Oncogene. 1997 Jan 30;14(4):491-8.
|
| REF 16 |
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis. Mol Cell. 1998 Dec;2(6):877-85.
|
| REF 17 |
Reconstitution of cyclin-dependent cdc2 and cdk2 kinase activities in vitro. J Biol Chem. 1993 Sep 25;268(27):20433-42.
|
| REF 18 |
BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage. Nat Genet. 2002 Mar;30(3):285-9.
|
| REF 19 |
Characterization of the in vitro reconstituted cyclin A or B1-dependent cdk2 and cdc2 kinase activities. J Biol Chem. 1993 Sep 25;268(27):20443-51.
|
| REF 20 |
Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function. J Cell Biol. 1995 Jun;129(6):1617-28.
|
| REF 21 |
Hip2 ubiquitin-conjugating enzyme overcomes radiation-induced G2/M arrest. Biochim Biophys Acta. 2013 Dec;1833(12):2911-2921.
|
| REF 22 |
Phosphorylation regulates SIRT1 function. PLoS One. 2008;3(12):e4020.
|
| REF 23 |
The anaphase-promoting complex or cyclosome supports cell survival in response to endoplasmic reticulum stress. PLoS One. 2012;7(4):e35520.
|
| REF 24 |
Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progression. Oncogene. 2008 Nov 6;27(52):6635-45.
|
| REF 25 |
Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor. J Proteome Res. 2008 Mar;7(3):1067-77.
|
| REF 26 |
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat Methods. 2014 May;11(5):585-92.
|
| REF 27 |
In silico prediction of physical protein interactions and characterization of interactome orphans. Nat Methods. 2015 Jan;12(1):79-84.
|
| REF 28 |
Activation of Src-like p56/p53lyn tyrosine kinase by ionizing radiation. J Biol Chem. 1994 Aug 12;269(32):20739-43.
|
| REF 29 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22;163(3):712-23.
|
| REF 30 |
Identification of a functional domain in a GADD45-mediated G2/M checkpoint. J Biol Chem. 2000 Nov 24;275(47):36892-8.
|
| REF 31 |
Cyclin F regulates the nuclear localization of cyclin B1 through a cyclin-cyclin interaction. EMBO J. 2000 Mar 15;19(6):1378-88.
|
| REF 32 |
Bortezomib potentially inhibits cellular growth of vascular endothelial cells through suppression of G2/M transition. Cancer Sci. 2010 Jun;101(6):1403-8.
|
| REF 33 |
cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner. EMBO J. 2008 Apr 9;27(7):1005-16.
|
| REF 34 |
A novel RING finger protein, human enhancer of invasion 10, alters mitotic progression through regulation of cyclin B levels. Mol Cell Biol. 2003 Mar;23(6):2109-22.
|
| REF 35 |
Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.
|
| REF 36 |
Response gene to complement 32 is required for C5b-9 induced cell cycle activation in endothelial cells. Exp Mol Pathol. 2009 Apr;86(2):87-94.
|
| REF 37 |
Effects of phosphorylation by CAK on cyclin binding by CDC2 and CDK2. Mol Cell Biol. 1995 Jan;15(1):345-50.
|
| REF 38 |
CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells. Nat Cell Biol. 2011 Jan;13(1):87-94.
|
| REF 39 |
Fine-tuning the stimulation of MLL1 methyltransferase activity by a histone H3-based peptide mimetic. FASEB J. 2011 Mar;25(3):960-7.
|
| REF 40 |
Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2. Nat Cell Biol. 2010 Nov;12(11):1108-14.
|
| REF 41 |
Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA. Genes Dev. 2010 Dec 1;24(23):2615-20.
|
| REF 42 |
PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression. Nucleic Acids Res. 2015 Apr 20;43(7):3591-604.
|
| REF 43 |
Downregulation of the cdc2/cyclin B protein kinase activity by binding of p53 to p34(cdc2). Biochem Biophys Res Commun. 2001 May 4;283(2):507-12.
|
| REF 44 |
The C-terminal regulatory domain of p53 contains a functional docking site for cyclin A. J Mol Biol. 2000 Jul 14;300(3):503-18.
|
| REF 45 |
Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells. Oncogene. 2012 Nov 22;31(47):4946-59.
|
| REF 46 |
Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis. Nucleic Acids Res. 2014 Dec 16;42(22):13573-87.
|
| REF 47 |
The TIP60 Complex Is a Conserved Coactivator of HIF1A. Cell Rep. 2016 Jun 28;16(1):37-47.
|
| REF 48 |
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1 to promote cell-cycle progression. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3325-34.
|
| REF 49 |
Cdc20 and Cks direct the spindle checkpoint-independent destruction of cyclin A. Mol Cell. 2008 May 9;30(3):290-302.
|
| REF 50 |
Ectopic expression of cdc2/cdc28 kinase subunit Homo sapiens 1 uncouples cyclin B metabolism from the mitotic spindle cell cycle checkpoint. Mol Cell Biol. 1998 Nov;18(11):6224-37.
|
| REF 51 |
A census of human soluble protein complexes. Cell. 2012 Aug 31;150(5):1068-81.
|
| REF 52 |
A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226.
|
| REF 53 |
APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase. Mol Cell. 2007 Aug 3;27(3):462-73.
|
| REF 54 |
The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression. J Biol Chem. 2000 Jun 2;275(22):16602-8.
|
| REF 55 |
S10 phosphorylation of p27 mediates atRA induced growth arrest in ovarian carcinoma cell lines. J Cell Physiol. 2008 Nov;217(2):558-68.
|
