Protein-Protein Interaction Details
| Protein General Information (TTD Target) | Top | ||||
|---|---|---|---|---|---|
| Full Name | G2/mitotic-specific cyclin B1 (CCNB1) | Patented-recorded | Target Info | ||
| UniProt ID | CCNB1_HUMAN | ||||
| Gene Name | CCNB1 | ||||
| Gene ID | 891 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Clinical trial Target(s) | Cyclin-dependent kinase 1 (CDK1) | Target Info | PPI Info | [1] | |
| Cyclin-dependent kinase 2 (CDK2) | Target Info | PPI Info | [2] | ||
| Transcription factor Sp1 (SP1) | Target Info | PPI Info | [3] | ||
| Interacting Literature-reported Target(s) | M-phase inducer phosphatase 1 (MPIP1) | Target Info | PPI Info | [4] | |
| Melanoma differentiation-associated protein 6 (CDKN1A) | Target Info | PPI Info | [5] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Identification of a functional domain in a GADD45-mediated G2/M checkpoint. J Biol Chem. 2000 Nov 24;275(47):36892-8. | ||||
| REF 2 | A nonproteolytic function of the proteasome is required for the dissociation of Cdc2 and cyclin B at the end of M phase. Genes Dev. 2000 Sep 15;14(18):2344-57. | ||||
| REF 3 | Sp1 phosphorylation by cyclin-dependent kinase 1/cyclin B1 represses its DNA-binding activity during mitosis in cancer cells. Oncogene. 2012 Nov 22;31(47):4946-59. | ||||
| REF 4 | Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. Mol Cell Proteomics. 2016 Sep;15(9):3030-44. | ||||
| REF 5 | LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. Nat Commun. 2013;4:1531. | ||||
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