| References |
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| REF 1 |
Concordant and opposite roles of DNA-PK and the "facilitator of chromatin transcription" (FACT) in DNA repair, apoptosis and necrosis after cisplatin. Mol Cancer. 2011 Jun 16;10:74.
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| REF 2 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22;163(3):712-23.
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| REF 3 |
Ku autoantigen (DNA helicase) is required for interleukins-13/-4-induction of 15-lipoxygenase-1 gene expression in human epithelial cells. Genes Immun. 2000;1(4):237-50.
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| REF 4 |
Regulation of osteocalcin gene expression by a novel Ku antigen transcription factor complex. J Biol Chem. 2002 Oct 4;277(40):37280-91.
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| REF 5 |
DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks. J Biol Chem. 2005 Feb 25;280(8):7060-9.
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| REF 6 |
Ku complex interacts with and stimulates the Werner protein. Genes Dev. 2000 Apr 15;14(8):907-12.
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| REF 7 |
The ACF1 complex is required for DNA double-strand break repair in human cells. Mol Cell. 2010 Dec 22;40(6):976-87.
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| REF 8 |
Coilin interacts with Ku proteins and inhibits in vitro non-homologous DNA end joining. FEBS Lett. 2010 Dec 1;584(23):4735-9.
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| REF 9 |
The Ku protein complex interacts with YY1, is up-regulated in human heart failure, and represses alpha myosin heavy-chain gene expression. Mol Cell Biol. 2004 Oct;24(19):8705-15.
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| REF 10 |
Ku80 binds to human replication origins prior to the assembly of the ORC complex. Biochemistry. 2005 May 31;44(21):7885-96.
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| REF 11 |
Ku recruits the XRCC4-ligase IV complex to DNA ends. Mol Cell Biol. 2000 May;20(9):2996-3003.
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| REF 12 |
Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines. Breast Cancer Res. 2009;11(6):R83.
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| REF 13 |
Chromatin association of XRCC5/6 in the absence of DNA damage depends on the XPE gene product DDB2. Mol Biol Cell. 2017 Jan 1;28(1):192-200.
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| REF 14 |
FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4. Mol Cell. 2016 Feb 4;61(3):419-433.
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| REF 15 |
Association of the Ku autoantigen/DNA-dependent protein kinase holoenzyme and poly(ADP-ribose) polymerase with the DNA binding domain of progesterone receptors. J Mol Endocrinol. 2000 Apr;24(2):165-82.
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| REF 16 |
Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.
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| REF 17 |
A high-throughput approach for measuring temporal changes in the interactome. Nat Methods. 2012 Sep;9(9):907-9.
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| REF 18 |
DNA damage modulates nucleolar interaction of the Werner protein with the AAA ATPase p97/VCP. Mol Biol Cell. 2003 Oct;14(10):4221-9.
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| REF 19 |
DNA-dependent protein kinase (DNA-PK) phosphorylates nuclear DNA helicase II/RNA helicase A and hnRNP proteins in an RNA-dependent manner. Nucleic Acids Res. 2004 Jan 2;32(1):1-10.
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| REF 20 |
Rapid recruitment of BRCA1 to DNA double-strand breaks is dependent on its association with Ku80. Mol Cell Biol. 2008 Dec;28(24):7380-93.
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| REF 21 |
BRCA1-Ku80 protein interaction enhances end-joining fidelity of chromosomal double-strand breaks in the G1 phase of the cell cycle. J Biol Chem. 2013 Mar 29;288(13):8966-76.
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| REF 22 |
Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway. Oncotarget. 2017 Jul 4;8(27):43733-43751.
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| REF 23 |
Ku antigen, an origin-specific binding protein that associates with replication proteins, is required for mammalian DNA replication. Biochim Biophys Acta. 2002 Oct 11;1578(1-3):59-72.
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| REF 24 |
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature. 2005 Mar 31;434(7033):605-11.
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| REF 25 |
Interplay between Ku, Artemis, and the DNA-dependent protein kinase catalytic subunit at DNA ends. J Biol Chem. 2006 Sep 22;281(38):27784-93.
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| REF 26 |
Binding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunit. J Biol Chem. 1997 Oct 3;272(40):24763-6.
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| REF 27 |
Mapping of protein-protein interactions within the DNA-dependent protein kinase complex. Nucleic Acids Res. 1999 Sep 1;27(17):3494-502.
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| REF 28 |
Human Ku70/80 associates physically with telomerase through interaction with hTERT. J Biol Chem. 2002 Dec 6;277(49):47242-7.
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| REF 29 |
The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. PLoS One. 2010 Aug 25;5(8):e12407.
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| REF 30 |
The human Rap1 protein complex and modulation of telomere length. J Biol Chem. 2004 Jul 2;279(27):28585-91.
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| REF 31 |
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in -Catenin-Active Cancers. Cell Syst. 2016 Sep 28;3(3):302-316.e4.
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| REF 32 |
Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling. Cancer Res. 2007 Feb 1;67(3):911-8.
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| REF 33 |
Poly(ADP-ribose) polymerase and Ku autoantigen form a complex and synergistically bind to matrix attachment sequences. J Biol Chem. 1999 Jul 16;274(29):20521-8.
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| REF 34 |
In prostate cancer cells the interaction of C/EBPalpha with Ku70, Ku80, and poly(ADP-ribose) polymerase-1 increases sensitivity to DNA damage. J Biol Chem. 2006 Apr 28;281(17):11496-505.
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| REF 35 |
A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein. J Biol Chem. 2002 Oct 25;277(43):40362-7.
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| REF 36 |
Chromatin-bound PCNA complex formation triggered by DNA damage occurs independent of the ATM gene product in human cells. Nucleic Acids Res. 2001 Mar 15;29(6):1341-51.
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| REF 37 |
The central role of EED in the orchestration of polycomb group complexes. Nat Commun. 2014;5:3127.
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| REF 38 |
BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery. J Neurosci. 2010 Jul 28;30(30):10096-111.
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