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| Target General Information |
Top |
| Target ID |
T76093 |
Target Info
|
| Target Name |
Proheparin-binding EGF-like growth factor (HBEGF) |
| Synonyms |
Proheparinbinding EGFlike growth factor; Heparinbinding EGFlike growth factor; Heparin-binding EGF-like growth factor; HEGFL; HB-EGF; Diphtheria toxin receptor; DTS; DTR; DT-R |
| Target Type |
Clinical trial Target |
| Gene Name |
HBEGF |
| Biochemical Class |
Growth factor |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Transcription regulators |
[+] 1 Transcription regulators |
+ |
| Interacting Protein Name |
Zinc finger and BTB domain-containing protein 16 (ZBTB16) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
PLZF; ZNF145 |
| Evidence Score (E-score) |
4 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[1] |
| 2 |
Reconstituted Complex |
[2] |
| 3 |
Reconstituted Complex |
[1] |
| 4 |
Yeast two hybrid |
[1] |
| References |
Top |
| REF 1 |
Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF. J Cell Biol. 2003 Nov 10;163(3):489-502.
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| REF 2 |
Roles of charged amino acid residues in the cytoplasmic domain of proHB-EGF. Biochem Biophys Res Commun. 2004 Jul 23;320(2):376-82.
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