Protein-Protein Interaction Details
Protein General Information | Top | ||||
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Full Name | Zinc finger and BTB domain-containing protein 16 (ZBTB16) | ||||
UniProt ID | ZBT16_HUMAN | ||||
Gene Name | ZBTB16 | ||||
Gene ID | 7704 |
Interacting TTD Target Information | Top | ||||
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Interacting Successful Target(s) | Histone deacetylase 1 (HDAC1) | Target Info | PPI Info | [1] | |
Interacting Clinical trial Target(s) | Histone deacetylase 4 (HDAC4) | Target Info | PPI Info | [2] | |
Proheparin-binding EGF-like growth factor (HBEGF) | Target Info | PPI Info | [3] | ||
Histone acetyltransferase p300 (EP300) | Target Info | PPI Info | [4] | ||
Polycomb complex protein BMI-1 (BMI1) | Target Info | PPI Info | [5] | ||
Interacting Patented-recorded Target(s) | Histone deacetylase 5 (HDAC5) | Target Info | PPI Info | [2] |
References | Top | ||||
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REF 1 | Histone deacetylase associated with mSin3A mediates repression by the acute promyelocytic leukemia-associated PLZF protein. Oncogene. 1998 May 14;16(19):2549-56. | ||||
REF 2 | HDAC4 mediates transcriptional repression by the acute promyelocytic leukaemia-associated protein PLZF. Oncogene. 2004 Nov 18;23(54):8777-84. | ||||
REF 3 | Proteolytic release of the carboxy-terminal fragment of proHB-EGF causes nuclear export of PLZF. J Cell Biol. 2003 Nov 10;163(3):489-502. | ||||
REF 4 | Histone acetyltransferase activity of p300 is required for transcriptional repression by the promyelocytic leukemia zinc finger protein. Mol Cell Biol. 2005 Jul;25(13):5552-66. | ||||
REF 5 | Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling. Dev Cell. 2002 Oct;3(4):499-510. |
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