| References |
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| REF 1 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22;163(3):712-23.
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| REF 2 |
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature. 2005 Mar 31;434(7033):605-11.
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| REF 3 |
Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage. BMC Mol Biol. 2012 Mar 9;13:7.
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| REF 4 |
Interplay between Ku, Artemis, and the DNA-dependent protein kinase catalytic subunit at DNA ends. J Biol Chem. 2006 Sep 22;281(38):27784-93.
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| REF 5 |
Association of the Ku autoantigen/DNA-dependent protein kinase holoenzyme and poly(ADP-ribose) polymerase with the DNA binding domain of progesterone receptors. J Mol Endocrinol. 2000 Apr;24(2):165-82.
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| REF 6 |
Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats. Nature. 2010 Jan 7;463(7277):118-21.
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| REF 7 |
Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.
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| REF 8 |
Binding of Ku and c-Abl at the kinase homology region of DNA-dependent protein kinase catalytic subunit. J Biol Chem. 1997 Oct 3;272(40):24763-6.
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| REF 9 |
Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes. EMBO J. 1999 Mar 1;18(5):1397-406.
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| REF 10 |
The NF90/NF45 complex participates in DNA break repair via nonhomologous end joining. Mol Cell Biol. 2011 Dec;31(23):4832-43.
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| REF 11 |
Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation. J Biol Chem. 2002 May 24;277(21):18291-302.
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| REF 12 |
Substrate specificities and identification of putative substrates of ATM kinase family members. J Biol Chem. 1999 Dec 31;274(53):37538-43.
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| REF 13 |
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination. Cell. 2002 Mar 22;108(6):781-94.
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| REF 14 |
Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response. Mol Cell Biol. 2004 Oct;24(20):9207-20.
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| REF 15 |
Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in -Catenin-Active Cancers. Cell Syst. 2016 Sep 28;3(3):302-316.e4.
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| REF 16 |
A census of human soluble protein complexes. Cell. 2012 Aug 31;150(5):1068-81.
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| REF 17 |
Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase. J Biol Chem. 2004 Sep 24;279(39):41189-96.
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| REF 18 |
DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA. EMBO J. 2005 Feb 23;24(4):779-89.
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| REF 19 |
Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation. J Biol Chem. 1999 Sep 3;274(36):25571-5.
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| REF 20 |
Phosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinase. J Biol Chem. 2004 Sep 3;279(36):37282-90.
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| REF 21 |
Identification of proteins associated with ligand-activated estrogen receptor in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS. Proteomics. 2011 Jan;11(1):172-9.
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| REF 22 |
A topoisomerase IIbeta-mediated dsDNA break required for regulated transcription. Science. 2006 Jun 23;312(5781):1798-802.
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| REF 23 |
Gene network analysis of oxidative stress-mediated drug sensitivity in resistant ovarian carcinoma cells. Pharmacogenomics J. 2010 Apr;10(2):94-104.
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| REF 24 |
Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complex. J Biol Chem. 2003 Aug 8;278(32):29940-7.
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| REF 25 |
Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase. J Biol Chem. 2000 Mar 17;275(11):7803-10.
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| REF 26 |
DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev. 1998 Sep 15;12(18):2831-41.
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| REF 27 |
DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D. Genes Dev. 1998 Jul 15;12(14):2188-99.
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| REF 28 |
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell. 1997 Oct 31;91(3):325-34.
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| REF 29 |
Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells. Nat Chem Biol. 2014 Dec;10(12):1000-2.
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| REF 30 |
Phosphorylation of nucleotide excision repair factor xeroderma pigmentosum group A by ataxia telangiectasia mutated and Rad3-related-dependent checkpoint pathway promotes cell survival in response to UV irradiation. Cancer Res. 2006 Mar 15;66(6):2997-3005.
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| REF 31 |
Sites of UV-induced phosphorylation of the p34 subunit of replication protein A from HeLa cells. J Biol Chem. 1997 Sep 19;272(38):23896-904.
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| REF 32 |
The DNA damage response in DNA-dependent protein kinase-deficient SCID mouse cells: replication protein A hyperphosphorylation and p53 induction. Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13825-30.
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| REF 33 |
DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase. J Biol Chem. 2004 Aug 13;279(33):34750-5.
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| REF 34 |
Interaction between DNA-dependent protein kinase and a novel protein, KIP. Mutat Res. 1997 Oct;385(1):13-20.
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| REF 35 |
DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45. J Biol Chem. 1998 Jan 23;273(4):2136-45.
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