| References |
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| REF 1 |
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Cell. 2006 Oct 6;127(1):125-37.
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| REF 2 |
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. EMBO J. 2008 Jul 23;27(14):1932-43.
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| REF 3 |
A new cytosolic pathway from a Parkinson disease-associated kinase, BRPK/PINK1: activation of AKT via mTORC2. J Biol Chem. 2011 Mar 4;286(9):7182-9.
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| REF 4 |
Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity. Genes Dev. 2006 Oct 15;20(20):2820-32.
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| REF 5 |
Identification of Protor as a novel Rictor-binding component of mTOR complex-2. Biochem J. 2007 Aug 1;405(3):513-22.
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| REF 6 |
mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide. EMBO J. 2010 Dec 1;29(23):3939-51.
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| REF 7 |
The target of rapamycin complex 2 controls dendritic tiling of Drosophila sensory neurons through the Tricornered kinase signalling pathway. EMBO J. 2009 Dec 16;28(24):3879-92.
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| REF 8 |
Substrate specificity of TOR complex 2 is determined by a ubiquitin-fold domain of the Sin1 subunit. Elife. 2017 Mar 7;6. pii: e19594.
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| REF 9 |
Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling. EMBO J. 2008 Jul 23;27(14):1919-31.
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| REF 10 |
Rictor forms a complex with Cullin-1 to promote SGK1 ubiquitination and destruction. Mol Cell. 2010 Sep 10;39(5):797-808.
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| REF 11 |
ER stress inhibits mTORC2 and Akt signaling through GSK-3-mediated phosphorylation of rictor. Sci Signal. 2011 Feb 22;4(161):ra10.
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| REF 12 |
Hsp70 associates with Rictor and is required for mTORC2 formation and activity. Biochem Biophys Res Commun. 2008 Aug 8;372(4):578-83.
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