| References |
Top |
| REF 1 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
|
| REF 2 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440.
|
| REF 3 |
The protein interaction landscape of the human CMGC kinase group. Cell Rep. 2013 Apr 25;3(4):1306-20.
|
| REF 4 |
A CDKN2A mutation in familial melanoma that abrogates binding of p16INK4a to CDK4 but not CDK6. Cancer Res. 2007 Oct 1;67(19):9134-41.
|
| REF 5 |
Hypo-phosphorylation of the retinoblastoma protein (pRb) by cyclin D:Cdk4/6 complexes results in active pRb. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10699-704.
|
| REF 6 |
Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature. 1998 Sep 17;395(6699):237-43.
|
| REF 7 |
OncoPPi-informed discovery of mitogen-activated protein kinase kinase 3 as a novel binding partner of c-Myc. Oncogene. 2017 Oct 19;36(42):5852-5860.
|
| REF 8 |
Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A. Curr Biol. 1996 Jan 1;6(1):84-91.
|
| REF 9 |
CAK-independent activation of CDK6 by a viral cyclin. Mol Biol Cell. 2001 Dec;12(12):3987-99.
|
| REF 10 |
Cdk6-cyclin D3 complex evades inhibition by inhibitor proteins and uniquely controls cell's proliferation competence. Oncogene. 2001 Apr 12;20(16):2000-9.
|
| REF 11 |
Functional characterization of human PFTK1 as a cyclin-dependent kinase. Proc Natl Acad Sci U S A. 2007 May 29;104(22):9248-53.
|
| REF 12 |
Identification of G1 kinase activity for cdk6, a novel cyclin D partner. Mol Cell Biol. 1994 Mar;14(3):2077-86.
|
| REF 13 |
Self-assembling protein microarrays. Science. 2004 Jul 2;305(5680):86-90.
|
| REF 14 |
Next-generation sequencing to generate interactome datasets. Nat Methods. 2011 Jun;8(6):478-80.
|
| REF 15 |
Pooled-matrix protein interaction screens using Barcode Fusion Genetics. Mol Syst Biol. 2016 Apr 22;12(4):863.
|
| REF 16 |
rec-YnH enables simultaneous many-by-many detection of direct protein-protein and protein-RNA interactions. Nat Commun. 2018 Sep 14;9(1):3747.
|
| REF 17 |
Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity. J Biol Chem. 2002 Dec 13;277(50):48827-33.
|
| REF 18 |
Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors. Genes Dev. 2000 Dec 15;14(24):3115-25.
|
| REF 19 |
Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes Dev. 1994 Dec 15;8(24):2939-52.
|
| REF 20 |
A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226.
|
| REF 21 |
Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d. Nature. 1998 Sep 17;395(6699):244-50.
|
| REF 22 |
CDK4 and CDK6 delay senescence by kinase-dependent and p16INK4a-independent mechanisms. Mol Cell Biol. 2007 Jun;27(12):4273-82.
|
| REF 23 |
Regulation of CDK4 activity by a novel CDK4-binding protein, p34(SEI-1). Genes Dev. 1999 Nov 15;13(22):3027-33.
|
| REF 24 |
Biologic and biochemical analyses of p16(INK4a) mutations from primary tumors. J Natl Cancer Inst. 1999 Sep 15;91(18):1569-74.
|
| REF 25 |
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis. Mol Cell. 1998 Dec;2(6):877-85.
|
| REF 26 |
Direct interaction of p21 cyclin-dependent kinase inhibitor with the retinoblastoma tumor suppressor protein. Biochem Biophys Res Commun. 1999 Sep 16;263(1):35-40.
|
| REF 27 |
Specific regulation of E2F family members by cyclin-dependent kinases. Mol Cell Biol. 1997 Jul;17(7):3867-75.
|
| REF 28 |
Cyclin D3 is down-regulated by rapamycin in HER-2-overexpressing breast cancer cells. Mol Cancer Ther. 2006 Sep;5(9):2172-81.
|
| REF 29 |
Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase. J Biol Chem. 1995 Aug 4;270(31):18195-7.
|
| REF 30 |
p300 is required for orderly G1/S transition in human cancer cells. Oncogene. 2007 Jan 4;26(1):21-9.
|
| REF 31 |
A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells. Cancer Cell. 2011 Nov 15;20(5):620-34.
|
| REF 32 |
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
|
| REF 33 |
Dephosphorylation of human cyclin-dependent kinases by protein phosphatase type 2C alpha and beta 2 isoforms. J Biol Chem. 2000 Nov 3;275(44):34744-9.
|
| REF 34 |
S10 phosphorylation of p27 mediates atRA induced growth arrest in ovarian carcinoma cell lines. J Cell Physiol. 2008 Nov;217(2):558-68.
|
