Target Validation Information | |||||
---|---|---|---|---|---|
TTD ID | T49639 | ||||
Target Name | Heat shock protein 70 (HSP70) | ||||
Type of Target |
Clinical trial |
||||
Drug Potency against Target | Adenosine triphosphate | Drug Info | IC50 = 3370 nM | [1] | |
ELLAGIC ACID | Drug Info | IC50 = 760 nM | [1] | ||
NSC-119910 | Drug Info | IC50 = 9850 nM | [1] | ||
NSC-119911 | Drug Info | IC50 = 332 nM | [1] | ||
NSC-119913 | Drug Info | IC50 = 634 nM | [1] | ||
References | |||||
REF 1 | In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. | ||||
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