Drug Information

Drug General Information
Drug ID
DXHL7D
Drug Name
(2-Chloro-phenyl)-[(3S,4R)-4-(4-chloro-phenyl)-1-methyl-pyrrolidin-3-yl]-methanone
Synonyms
CHEMBL269445
Indication Discovery agent Investigative [1587926]
Formula
C18H17Cl2NO
Canonical SMILES
CN1C[C@H]([C@@H](C1)c2ccc(Cl)cc2)C(=O)c3ccccc3Cl
InChI
InChI=1S/C18H17Cl2NO/c1-21-10-15(12-6-8-13(19)9-7-12)16(11-21)18(22)14-4-2-3-5-17(14)20/h2-9,15-16H,10-11H2,1H3/t15-,16+/m0/s1
InChIKey
TZYCOGSJLNLMCK-JKSUJKDBSA-N
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info [1587926]
Sodium-dependent serotonin transporter Target Info [1587926]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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