Drug Information
Drug General Information | |||||
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Drug ID |
D06SDG
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Former ID |
DNC013169
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Drug Name |
D[Leu4,Dab8]VP
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [528674] | ||
Structure |
Download2D MOL |
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Formula |
C45H63N11O11S2
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Canonical SMILES |
CC(C)CC1C(=O)NC(C(=O)NC(CSSCCC(=O)NC(C(=O)NC(C(=O)N1)CC<br />2=CC=CC=C2)CC3=CC=C(C=C3)O)C(=O)N4CCCC4C(=O)NC(CCN)C(=O<br />)NCC(=O)N)CC(=O)N
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InChI |
1S/C45H63N11O11S2/c1-25(2)19-30-40(62)54-33(22-36(47)58)43(65)55-34(45(67)56-17-6-9-35(56)44(66)51-29(14-16-46)39(61)49-23-37(48)59)24-69-68-18-15-38(60)50-31(21-27-10-12-28(57)13-11-27)41(63)53-32(42(64)52-30)20-26-7-4-3-5-8-26/h3-5,7-8,10-13,25,29-35,57H,6,9,14-24,46H2,1-2H3,(H2,47,58)(H2,48,59)(H,49,61)(H,50,60)(H,51,66)(H,52,64)(H,53,63)(H,54,62)(H,55,65)/t29-,30-,31-,32-,33-,34-,35-/m0/s1
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InChIKey |
VIYXBPSZIAMFAA-POFDKVPJSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Vasopressin V1a receptor | Target Info | Inhibitor | [528674] | |
Oxytocin receptor | Target Info | Inhibitor | [528674] | ||
Vasopressin V1b receptor | Target Info | Inhibitor | [528674] | ||
Vasopressin V2 receptor | Target Info | Inhibitor | [528674] | ||
KEGG Pathway | Calcium signaling pathway | ||||
Neuroactive ligand-receptor interaction | |||||
Vascular smooth muscle contractionhsa04020:Calcium signaling pathway | |||||
cAMP signaling pathway | |||||
Oxytocin signaling pathwayhsa04020:Calcium signaling pathway | |||||
Vascular smooth muscle contractionhsa04080:Neuroactive ligand-receptor interaction | |||||
Vasopressin-regulated water reabsorption | |||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
PANTHER Pathway | Oxytocin receptor mediated signaling pathway | ||||
Pathway Interaction Database | Arf6 trafficking events | ||||
PathWhiz Pathway | Vasopressin Regulation of Water Homeostasis | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
Gastrin-CREB signalling pathway via PKC and MAPK | |||||
Peptide GPCRs | |||||
GPCR ligand binding | |||||
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like | |||||
Myometrial Relaxation and Contraction Pathways | |||||
Oxytocin signaling | |||||
Regulation of Water Balance by Renal Aquaporins | |||||
GPCR downstream signaling | |||||
References |
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