| Drug General Information |
| Drug ID |
D07ONX
|
| Former ID |
DNC002434
|
| Drug Name |
Beta-D-Glucose
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C6H12O6
|
| Canonical SMILES |
C(C1C(C(C(C(O1)O)O)O)O)O
|
| InChI |
1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
|
| InChIKey |
WQZGKKKJIJFFOK-VFUOTHLCSA-N
|
| CAS Number |
CAS 50-99-7
|
| PubChem Compound ID |
|
| PubChem Substance ID |
2746, 3521, 583874, 584687, 584724, 584729, 585301, 585542, 595815, 820130, 820136, 820523, 820544, 821055, 821063, 821137, 821437, 821781, 821799, 821918, 822175, 822180, 822198, 822490, 822493, 822554, 822648, 822692, 822701, 822938, 823022, 823135, 823266, 823285, 823454, 823855, 823862, 823918, 824102, 825229, 825975, 825977, 826009, 826728, 826798, 827888, 827890, 827912, 827915, 828350
|
| Target and Pathway |
| Target(s) |
Glucokinase |
Target Info |
Inhibitor |
[1]
|
|---|
| Enoyl-[acyl-carrier-protein] reductase [NADH] |
Target Info |
Inhibitor |
[1]
|
| Prostaglandin G/H synthase 1 |
Target Info |
Inhibitor |
[1]
|
| Enoyl-ACP reductase |
Target Info |
Inhibitor |
[1]
|
| Glycogen phosphorylase, muscle form |
Target Info |
Inhibitor |
[1]
|
| Pancreatic alpha-amylase |
Target Info |
Inhibitor |
[1]
|
| Alpha-glucosidase |
Target Info |
Inhibitor |
[1]
|
| DNA |
Target Info |
Inhibitor |
[1]
|
|
BioCyc Pathway
|
C20 prostanoid biosynthesisPWY-5941:Glycogenolysis
|
|
KEGG Pathway
|
Glycolysis / Gluconeogenesis
|
|
Galactose metabolism
|
|
Starch and sucrose metabolism
|
|
Amino sugar and nucleotide sugar metabolism
|
|
Butirosin and neomycin biosynthesis
|
|
Metabolic pathways
|
|
Biosynthesis of antibiotics
|
|
Carbon metabolism
|
|
Insulin signaling pathway
|
|
Insulin secretion
|
|
Prolactin signaling pathway
|
|
Glucagon signaling pathway
|
|
Type II diabetes mellitus
|
|
Maturity onset diabetes of the young
|
|
Central carbon metabolism in cancerhsa00590:Arachidonic acid metabolism
|
|
Platelet activation
|
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Serotonergic synapsehsa00500:Starch and sucrose metabolism
|
|
NetPath Pathway
|
TGF_beta_Receptor Signaling Pathway
|
|
PANTHER Pathway
|
Inflammation mediated by chemokine and cytokine signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
|
Pathway Interaction Database
|
FOXA2 and FOXA3 transcription factor networks
|
|
HIF-1-alpha transcription factor network
|
|
PathWhiz Pathway
|
Nucleotide Sugars Metabolism
|
|
Starch and Sucrose Metabolism
|
|
Galactose Metabolism
|
|
Trehalose DegradationPW000044:Arachidonic Acid Metabolism
|
|
Reactome
|
Regulation of gene expression in beta cells
|
|
Glucose transport
|
|
Glycolysis
|
|
WikiPathways
|
SIDS Susceptibility Pathways
|
|
Glycolysis and Gluconeogenesis
|
|
MAPK Signaling Pathway
|
|
Regulation of beta-cell development
|
|
Metabolism of carbohydrates
|
|
Hexose transportWP98:Prostaglandin Synthesis and Regulation
|
|
Arachidonic acid metabolism
|
|
Phase 1 - Functionalization of compounds
|
|
Eicosanoid Synthesis
|
|
Selenium Micronutrient NetworkWP500:Glycogen Metabolism
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
