Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D09NYS
|
||||
| Former ID |
DNC000937
|
||||
| Drug Name |
Methylene blue
|
||||
| Indication | Acquired methemoglobinemia | Approved | [538085] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C16H18ClN3S
|
||||
| Canonical SMILES |
CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-]
|
||||
| InChI |
1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1
|
||||
| InChIKey |
CXKWCBBOMKCUKX-UHFFFAOYSA-M
|
||||
| CAS Number |
CAS 61-73-4
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID |
3520, 488109, 538590, 566674, 3289278, 8153816, 10321389, 10530028, 14874685, 14923801, 24811249, 24845631, 24850898, 24858888, 24884898, 26759142, 29225108, 46530520, 48416255, 49748044, 49854486, 53790898, 57323186, 57672493, 79074222, 87562160, 87563123, 87572543, 88337470, 92714081, 103568829, 104311118, 105033330, 118274266, 118508441, 124594625, 125062930, 126629670, 126677876, 134340221, 134342579, 134971203, 135377216, 135697796, 137002768, 137156936, 143434995, 143552340, 144075873, 144206050
|
||||
| ChEBI ID |
ChEBI:6872
|
||||
| SuperDrug ATC ID |
V03AB17; V04CG05
|
||||
| SuperDrug CAS ID |
cas=000061734
|
||||
| Target and Pathway | |||||
| Target(s) | DNA | Target Info | [537544] | ||
| Glutathione reductase, mitochondrial | Target Info | Inhibitor | [538085] | ||
| Guanylate cyclase | Target Info | Inhibitor | [537384] | ||
| References | |||||
| Ref 537384 | Curcumin ameliorates high glucose-induced acute vascular endothelial dysfunction in rat thoracic aorta. Clin Exp Pharmacol Physiol. 2009 May 19. | ||||
| Ref 537544 | Photoluminescence of CdTe nanocrystals modulated by methylene blue and DNA. A label-free luminescent signaling nanohybrid platform. Phys Chem Chem Phys. 2009 Jul 7;11(25):5062-9. Epub 2009 Mar 26. | ||||
| Ref 538085 | Recombinant Plasmodium falciparum glutathione reductase is inhibited by the antimalarial dye methylene blue. FEBS Lett. 1998 Feb 6;422(3):311-4. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.