Drug General Information
Drug ID	D0D0BI
Former ID	DNC005438
Drug Name	CHLORANIL
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527510]
Structure		Download 2D MOL 3D MOL
Formula	C6Cl4O2
Canonical SMILES	C1(=C(C(=O)C(=C(C1=O)Cl)Cl)Cl)Cl
InChI	1S/C6Cl4O2/c7-1-2(8)6(12)4(10)3(9)5(1)11
InChIKey	UGNWTBMOAKPKBL-UHFFFAOYSA-N
PubChem Compound ID	8371
Target and Pathway
Target(s)	Liver carboxylesterase	Target Info	Inhibitor	[527510]
	Acetylcholinesterase	Target Info	Inhibitor	[527510]
	Cholinesterase	Target Info	Inhibitor	[527510]
KEGG Pathway	Drug metabolism - other enzymes
	Metabolic pathwayshsa00564:Glycerophospholipid metabolism
	Cholinergic synapse
PANTHER Pathway	Muscarinic acetylcholine receptor 1 and 3 signaling pathway
	Muscarinic acetylcholine receptor 2 and 4 signaling pathway
	Nicotinic acetylcholine receptor signaling pathwayP00042:Muscarinic acetylcholine receptor 1 and 3 signaling pathway
	Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database	E2F transcription factor networkatf2_pathway:ATF-2 transcription factor network
PathWhiz Pathway	Phospholipid Biosynthesis
WikiPathways	NRF2 pathway
	Nuclear Receptors Meta-Pathway
	Heroin metabolism
	Irinotecan Pathway
	Fluoropyrimidine Activity
	Phase I biotransformations, non P450WP727:Monoamine Transport
	Biogenic Amine Synthesis
	Acetylcholine Synthesis
	Integrated Pancreatic Cancer PathwayWP229:Irinotecan Pathway
References
Ref 527510	J Med Chem. 2005 Apr 21;48(8):2906-15.Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.
Ref 527510	J Med Chem. 2005 Apr 21;48(8):2906-15.Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.

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