Drug General Information
Drug ID	D0I3UA
Former ID	DNC014075
Drug Name	7-Oxo-7H-dibenzo[de,g]quinoline
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529985]
Structure		Download 2D MOL 3D MOL
Formula	C16H9NO
Canonical SMILES	C1=CC=C2C(=C1)C3=CC=CC4=C3C(=NC=C4)C2=O
InChI	1S/C16H9NO/c18-16-13-6-2-1-5-11(13)12-7-3-4-10-8-9-17-15(16)14(10)12/h1-9H
InChIKey	GHWKWAMIXPOYPG-UHFFFAOYSA-N
PubChem Compound ID	326183
Target and Pathway
Target(s)	Cholinesterase	Target Info	Inhibitor	[529985]
	Acetylcholinesterase	Target Info	Inhibitor	[529985]
KEGG Pathway	Glycerophospholipid metabolism
	Cholinergic synapse
PANTHER Pathway	Muscarinic acetylcholine receptor 1 and 3 signaling pathway
	Muscarinic acetylcholine receptor 2 and 4 signaling pathway
	Nicotinic acetylcholine receptor signaling pathwayP00042:Muscarinic acetylcholine receptor 1 and 3 signaling pathway
	Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database	ATF-2 transcription factor network
PathWhiz Pathway	Phospholipid Biosynthesis
WikiPathways	Irinotecan PathwayWP727:Monoamine Transport
	Biogenic Amine Synthesis
	Acetylcholine Synthesis
	Integrated Pancreatic Cancer Pathway
References
Ref 529985	Eur J Med Chem. 2009 Jun;44(6):2523-32. Epub 2009 Jan 31.Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase.
Ref 529985	Eur J Med Chem. 2009 Jun;44(6):2523-32. Epub 2009 Jan 31.Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.