Drug Information

Drug General Information
Drug ID
D0W9JK
Former ID
DNC010177
Drug Name
(S)-N-isobutyl-N-(pyrrolidin-3-yl)-2-naphthamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530367]
Structure
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2D MOL

3D MOL
Formula
C19H24N2O
Canonical SMILES
CC(C)CN(C1CCNC1)C(=O)C2=CC3=CC=CC=C3C=C2
InChI
1S/C19H24N2O/c1-14(2)13-21(18-9-10-20-12-18)19(22)17-8-7-15-5-3-4-6-16(15)11-17/h3-8,11,14,18,20H,9-10,12-13H2,1-2H3/t18-/m0/s1
InChIKey
CEUJKSVEPJAVKD-SFHVURJKSA-N
PubChem Compound ID
11220185
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info Inhibitor [530367]
Sodium-dependent serotonin transporter Target Info Inhibitor [530367]
KEGG Pathway Serotonergic synapse
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP04373:5HT1 type receptor mediated signaling pathway
5HT2 type receptor mediated signaling pathway
5HT3 type receptor mediated signaling pathway
5HT4 type receptor mediated signaling pathway
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
SIDS Susceptibility Pathways
Synaptic Vesicle Pathway
Serotonin Transporter Activity
References
Ref 530367Bioorg Med Chem Lett. 2009 Oct 15;19(20):5893-7. Epub 2009 Aug 21.Design and optimisation of selective serotonin re-uptake inhibitors with high synthetic accessibility: part 2.
Ref 530367Bioorg Med Chem Lett. 2009 Oct 15;19(20):5893-7. Epub 2009 Aug 21.Design and optimisation of selective serotonin re-uptake inhibitors with high synthetic accessibility: part 2.

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