Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0ZD0W
|
||||
Former ID |
DNC013167
|
||||
Drug Name |
D[Orn4]AVP
|
||||
Indication | Discovery agent | Investigative | [528674] | ||
Structure |
Download2D MOL |
||||
Formula |
C46H66N14O11S2
|
||||
Canonical SMILES |
C1CC(N(C1)C(=O)C2CSSCCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C<br />(=O)N2)CC(=O)N)CCCN)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)C(=O)N<br />C(CCCN=C(N)N)C(=O)NCC(=O)N
|
||||
InChI |
1S/C46H66N14O11S2/c47-17-4-9-30-40(66)58-33(23-36(48)62)43(69)59-34(45(71)60-19-6-11-35(60)44(70)56-29(10-5-18-52-46(50)51)39(65)53-24-37(49)63)25-73-72-20-16-38(64)54-31(22-27-12-14-28(61)15-13-27)41(67)57-32(42(68)55-30)21-26-7-2-1-3-8-26/h1-3,7-8,12-15,29-35,61H,4-6,9-11,16-25,47H2,(H2,48,62)(H2,49,63)(H,53,65)(H,54,64)(H,55,68)(H,56,70)(H,57,67)(H,58,66)(H,59,69)(H4,50,51,52)/t29-,30-,31-,32-,33-,34-,35-/m0/s1
|
||||
InChIKey |
HBVZQPKQFUSYKR-POFDKVPJSA-N
|
||||
PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Vasopressin V2 receptor | Target Info | Inhibitor | [528674] | |
Vasopressin V1a receptor | Target Info | Inhibitor | [528674] | ||
Oxytocin receptor | Target Info | Inhibitor | [528674] | ||
Vasopressin V1b receptor | Target Info | Inhibitor | [528674] | ||
KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
Vasopressin-regulated water reabsorptionhsa04020:Calcium signaling pathway | |||||
Vascular smooth muscle contractionhsa04020:Calcium signaling pathway | |||||
cAMP signaling pathway | |||||
Oxytocin signaling pathwayhsa04020:Calcium signaling pathway | |||||
Vascular smooth muscle contraction | |||||
NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
PANTHER Pathway | Oxytocin receptor mediated signaling pathway | ||||
Pathway Interaction Database | Arf6 trafficking events | ||||
PathWhiz Pathway | Vasopressin Regulation of Water Homeostasis | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
Regulation of Water Balance by Renal Aquaporins | |||||
Peptide GPCRs | |||||
GPCR ligand binding | |||||
GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like | |||||
Gastrin-CREB signalling pathway via PKC and MAPK | |||||
Myometrial Relaxation and Contraction Pathways | |||||
Oxytocin signaling | |||||
GPCR downstream signaling | |||||
References |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.