Drug General Information
Drug ID
D05JNI
Former ID
DAP000838
Drug Name
Framycetin
Synonyms
Actilin; Actiline; Antibiotique; Endomixin; Enterfram; Fradiomycin; Fradiomycinum; Framicetina; Framycetine; Framycetinum; Framygen; Fraquinol; Myacine; Myacyne; Mycifradin; Myciguent; NMY; Neobiotic; Neobrettin; Neolate; Neomas; Neomcin; Neomicina; Neomin; Neomycin; Neomycine; Neomycinum; Nivemycin; PIMAVECORT; Soframycin; Soframycine; Tuttomycin; VONAMYCIN; Fradiomycin B; NEOMYCIN AND POLYMYXIN B SULFATES; NEOMYCIN B; NEOMYCIN SULFATE; Neomicina [DCIT]; Neomycin B sulfate; Neomycin solution; Soframycin Ophthalmic; Vonamycin powder V; Antibiotic 10676; Antibiotic produced by Streptomyces decaris. Neomycin B; Framicetina [INN-Spanish]; Framycetin (INN); Framycetine [INN-French]; Framycetinum [INN-Latin]; Neo-Fradin; Neo-Rx; Neomycine [INN-French]; Neomycinum [INN-Latin]; Soframycin (TN); USAF CB-19; Framycetin [INN:BAN:DCF]; Sofra-Tulle (TN); BDG-(1-4)CYY-(5-1)RIB-(3-1)IDG; BDG-(1-4)NEB-(5-1)RIB-(3-1)NED; (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside; (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol; D-Streptamine, O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1.->3)-O-.beta.-D-ribofuranosyl-(1->5)]-O-[2,6-diamino-2,6-dideoxy-.alpha.-D-glucopyranosyl-(1->4)]-2-deoxy
Drug Type
Small molecular drug
Indication Bacterial infections [ICD9: 001-009, 010-018, 020-027, 030-041, 080-088, 090-099, 100-104; ICD10:A00-B99] Approved [550693]
Therapeutic Class
Antibiotics
Structure
Download
2D MOL

3D MOL

Formula
C23H46N6O13
Canonical SMILES
C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)N)OC3C(C(C(O3)CO)OC4<br />C(C(C(C(O4)CN)O)O)N)O)O)N
InChI
1S/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+/m1/s1
InChIKey
PGBHMTALBVVCIT-VCIWKGPPSA-N
CAS Number
CAS 119-04-0
PubChem Compound ID
PubChem Substance ID
ChEBI ID
ChEBI:7508
SuperDrug ATC ID
A01AB08; A07AA01; B05CA09; D06AX04; D09AA01; J01GB05; R01AX08; R02AB01; S01AA03; S01AA07; S02AA07; S03AA01
SuperDrug CAS ID
cas=000119040
Target and Pathway
Target(s) 16S rRNA Target Info Binder [535064]
30S ribosomal subunit Target Info Binder [535064]
References
Ref 550693Drug information of Framycetin, 2008. eduDrugs.
Ref 535064Antistaphylococcal activity of gentamicin. Minerva Med. 1975 Dec 8;66(84):4505-26.

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