Drug Information
Drug General Information | |||||
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Drug ID |
D0O6QW
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Former ID |
DIB014579
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Drug Name |
Manifaxine
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Synonyms |
BW-1555U88; GW-320659; GW-320659A
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Drug Type |
Small molecular drug
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Indication | Major depressive disorder [ICD9: 296.2, 296.3, 710.0; ICD10:F32, F33, M32] | Discontinued in Phase 2 | [546210] | ||
Company |
Glaxo Wellcome plc
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Structure |
Download2D MOL |
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Formula |
C12H15F2NO2
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Canonical SMILES |
[C@]1(c2cc(cc(c2)F)F)(OC[C@H](N[C@H]1C)C)O
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Sodium-dependent noradrenaline transporter | Target Info | Modulator | [527845] | |
Sodium-dependent dopamine transporter | Target Info | Modulator | [527845] | ||
Pathway Interaction Database | Alpha-synuclein signaling | ||||
WikiPathways | Monoamine Transport | ||||
NRF2 pathway | |||||
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport | |||||
Dopaminergic Neurogenesis | |||||
Parkinsons Disease Pathway | |||||
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | |||||
Neurotransmitter Clearance In The Synaptic Cleft | |||||
References |
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