Target General Infomation
Target ID
T76522
Former ID
TTDR01201
Target Name
Pyridoxal kinase
Gene Name
PDXK
Synonyms
Pyridoxine kinase; PDXK
Target Type
Research
Function
Required for synthesisof pyridoxal-5-phosphate from vitamin B6.
BioChemical Class
Kinase
UniProt ID
EC Number
EC 2.7.1.35
Sequence
MEEECRVLSIQSHVIRGYVGNRAATFPLQVLGFEIDAVNSVQFSNHTGYAHWKGQVLNSD
ELQELYEGLRLNNMNKYDYVLTGYTRDKSFLAMVVDIVQELKQQNPRLVYVCDPVLGDKW
DGEGSMYVPEDLLPVYKEKVVPLADIITPNQFEAELLSGRKIHSQEEALRVMDMLHSMGP
DTVVITSSDLPSPQGSNYLIVLGSQRRRNPAGSVVMERIRMDIRKVDAVFVGTGDLFAAM
LLAWTHKHPNNLKVACEKTVSTLHHVLQRTIQCAKAQAGEGVRPSPMQLELRMVQSKRDI
EDPEIVVQATVL
Inhibitor Adenosine-5'-Diphosphate Drug Info [551391]
Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate Drug Info [551393]
Pathways
BioCyc Pathway Pyridoxal 5&#039
-phosphate salvage
KEGG Pathway Vitamin B6 metabolism
Metabolic pathways
NetPath Pathway FSH Signaling Pathway
PANTHER Pathway Pyridoxal phosphate salvage pathway
Vitamin B6 metabolism
PathWhiz Pathway Vitamin B6 Metabolism
WikiPathways Metabolism of water-soluble vitamins and cofactors
References
Ref 551391DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-4. Nucleic Acids Res. 2011 January
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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