Drug General Information
Drug ID
D01OZS
Former ID
DNC011579
Drug Name
3,3-Diisopropyl-dihydro-furan-2-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533975]
Structure
Download
2D MOL

3D MOL

Formula
C10H18O2
Canonical SMILES
CC(C)C1(CCOC1=O)C(C)C
InChI
1S/C10H18O2/c1-7(2)10(8(3)4)5-6-12-9(10)11/h7-8H,5-6H2,1-4H3
InChIKey
HBNIKFYZKDWFNE-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit beta-2 Target Info Inhibitor [533975]
Gamma-aminobutyric acid receptor Target Info Inhibitor [533975]
Gamma-aminobutyric acid receptor subunit gamma-2 Target Info Inhibitor [533975]
Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533975]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
Serotonergic synapse
GABAergic synapse
Morphine addiction
Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activationR-HSA-975298:Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transportWP706:SIDS Susceptibility Pathways
Iron uptake and transport
References
Ref 533975J Med Chem. 1994 Jan 21;37(2):275-86.Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones.
Ref 533975J Med Chem. 1994 Jan 21;37(2):275-86.Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.