Drug General Information
Drug ID
D02HRB
Former ID
DNC011678
Drug Name
RWJ-16979
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533762]
Structure
Download
2D MOL

3D MOL

Formula
C18H15N3O2
Canonical SMILES
C1CN2C3=CC=CC=C3NC2=C(C1=O)C(=O)NC4=CC=CC=C4
InChI
1S/C18H15N3O2/c22-15-10-11-21-14-9-5-4-8-13(14)20-17(21)16(15)18(23)19-12-6-2-1-3-7-12/h1-9,20H,10-11H2,(H,19,23)
InChIKey
AOXBTUWPBDHMSU-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor Target Info Inhibitor [533762]
Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533762]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 533762J Med Chem. 1995 Jan 6;38(1):16-20.Potential anxiolytic agents. Pyrido[1,2-a]benzimidazoles: a new structural class of ligands for the benzodiazepine binding site on GABA-A receptors.
Ref 533762J Med Chem. 1995 Jan 6;38(1):16-20.Potential anxiolytic agents. Pyrido[1,2-a]benzimidazoles: a new structural class of ligands for the benzodiazepine binding site on GABA-A receptors.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.