TTD | Drug: D04JTK

Drug General Information
Drug ID	D04JTK
Former ID	DNC011499
Drug Name	(6-Benzylamino-9H-beta-carbolin-3-yl)-methanol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533414]
Structure		Download 2D MOL 3D MOL
Formula	C19H17N3O
Canonical SMILES	C1=CC=C(C=C1)CNC2=CC3=C(C=C2)NC4=CN=C(C=C34)CO
InChI	1S/C19H17N3O/c23-12-15-9-17-16-8-14(20-10-13-4-2-1-3-5-13)6-7-18(16)22-19(17)11-21-15/h1-9,11,20,22-23H,10,12H2
InChIKey	PCESGKMKSBKSOT-UHFFFAOYSA-N
PubChem Compound ID	5387929
Target and Pathway
Target(s)	Gamma-aminobutyric acid receptor subunit alpha-1	Target Info	Inhibitor	[533414]
Target(s)	Gamma-aminobutyric acid receptor	Target Info	Inhibitor	[533414]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
Reactome	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 533414	J Med Chem. 1987 Apr;30(4):750-3.Synthesis of 6-substituted beta-carbolines that behave as benzodiazepine receptor antagonists or inverse agonists.
Ref 533414	J Med Chem. 1987 Apr;30(4):750-3.Synthesis of 6-substituted beta-carbolines that behave as benzodiazepine receptor antagonists or inverse agonists.

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Drug Information