Drug Information

Drug General Information
Drug ID
D06ZOM
Former ID
DNC011495
Drug Name
3-Methyl-2-phenyl-2H-chromeno[4,3-c]pyrazol-4-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533354]
Structure
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2D MOL

3D MOL
Formula
C17H12N2O2
Canonical SMILES
CC1=C2C(=NN1C3=CC=CC=C3)C4=CC=CC=C4OC2=O
InChI
1S/C17H12N2O2/c1-11-15-16(18-19(11)12-7-3-2-4-8-12)13-9-5-6-10-14(13)21-17(15)20/h2-10H,1H3
InChIKey
VJSRCIFAUSKZHJ-UHFFFAOYSA-N
PubChem Compound ID
15569045
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533354]
Gamma-aminobutyric acid receptor Target Info Inhibitor [533354]
Gamma-aminobutyric acid receptor subunit gamma-2 Target Info Inhibitor [533354]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activationR-HSA-975298:Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 533354J Med Chem. 1988 Jan;31(1):1-3.Synthesis, binding studies, and structure-activity relationships of 1-aryl-and 2-aryl[1]benzopyranopyrazol-4-ones, central benzodiazepine receptor ligands.
Ref 533354J Med Chem. 1988 Jan;31(1):1-3.Synthesis, binding studies, and structure-activity relationships of 1-aryl-and 2-aryl[1]benzopyranopyrazol-4-ones, central benzodiazepine receptor ligands.

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