Drug General Information
Drug ID	D07MRF
Former ID	DNC012344
Drug Name	3-Nitro-9H-beta-carboline
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533363]
Structure		Download 2D MOL 3D MOL
Formula	C11H7N3O2
Canonical SMILES	C1=CC=C2C(=C1)C3=CC(=NC=C3N2)[N+](=O)[O-]
InChI	1S/C11H7N3O2/c15-14(16)11-5-8-7-3-1-2-4-9(7)13-10(8)6-12-11/h1-6,13H
InChIKey	XQNOYQREYCKAIN-UHFFFAOYSA-N
PubChem Compound ID	4713455
Target and Pathway
Target(s)	Gamma-aminobutyric acid receptor	Target Info	Inhibitor	[533363]
	Gamma-aminobutyric acid receptor subunit alpha-1	Target Info	Inhibitor	[533363]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 533363	J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.
Ref 533363	J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.

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