Drug General Information
Drug ID
D0B4WR
Former ID
DNC012031
Drug Name
2-Isoxazol-5-yl-3H-imidazo[4,5-c]quinoline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534155]
Structure
Download
2D MOL

3D MOL

Formula
C13H8N4O
Canonical SMILES
C1=CC=C2C(=C1)C3=NC(=C4C=CNO4)N=C3C=N2
InChI
1S/C13H8N4O/c1-2-4-9-8(3-1)12-10(7-14-9)16-13(17-12)11-5-6-15-18-11/h1-7,15H/b13-11-
InChIKey
DUIZUGINLYIMFH-QBFSEMIESA-N
PubChem Compound ID
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [534155]
Gamma-aminobutyric acid receptor subunit beta-2 Target Info Inhibitor [534155]
Gamma-aminobutyric acid receptor subunit gamma-2 Target Info Inhibitor [534155]
Gamma-aminobutyric acid receptor Target Info Inhibitor [534155]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
Serotonergic synapse
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activationR-HSA-975298:Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 534155J Med Chem. 1996 Jul 5;39(14):2844-51.Synthesis and structure--activity relationships of fused imidazopyridines: a new series of benzodiazepine receptor ligands.
Ref 534155J Med Chem. 1996 Jul 5;39(14):2844-51.Synthesis and structure--activity relationships of fused imidazopyridines: a new series of benzodiazepine receptor ligands.

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