Drug Information
Drug General Information | |||||
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Drug ID |
D0J0CA
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Former ID |
DNC011810
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Drug Name |
BETA-CCM
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [533745] | ||
Structure |
Download2D MOL |
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Formula |
C13H10N2O2
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Canonical SMILES |
COC(=O)C1=NC=C2C(=C1)C3=CC=CC=C3N2
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InChI |
1S/C13H10N2O2/c1-17-13(16)11-6-9-8-4-2-3-5-10(8)15-12(9)7-14-11/h2-7,15H,1H3
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InChIKey |
UKHFPVCOXBJPIN-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Gamma-aminobutyric acid receptor subunit beta-2 | Target Info | Inhibitor | [533745] | |
Gamma-aminobutyric acid receptor | Target Info | Inhibitor | [533763] | ||
Gamma-aminobutyric acid receptor subunit gamma-2 | Target Info | Inhibitor | [533546] | ||
Gamma-aminobutyric acid receptor subunit alpha-1 | Target Info | Inhibitor | [533763] | ||
WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
Iron uptake and transportWP706:SIDS Susceptibility Pathways | |||||
Iron uptake and transport | |||||
References | |||||
Ref 533546 | J Med Chem. 1983 Apr;26(4):499-503.beta-Carbolines as benzodiazepine receptor ligands. 1. Synthesis and benzodiazepine receptor interaction of esters of beta-carboline-3-carboxylic acid. | ||||
Ref 533745 | J Med Chem. 1994 Dec 23;37(26):4576-80.Four amino acid exchanges convert a diazepam-insensitive, inverse agonist-preferring GABAA receptor into a diazepam-preferring GABAA receptor. | ||||
Ref 533763 | J Med Chem. 1995 Jan 6;38(1):189-98.Synthetic routes to 4-amino-3-carboxy-beta-carboline derivatives: incidental formation of novel furo[3,4-c]-beta-carbolin-2-ones displaying high affinities for thebenzodiazepine receptor. |
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