Drug Information
Drug General Information | |||||
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Drug ID |
D0N1HE
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Former ID |
DIB021112
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Drug Name |
UCL1848
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Synonyms |
UCL-1848
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [539468] | ||
Structure |
Download2D MOL |
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Formula |
C28H34N4+2
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InChI |
InChI=1S/C28H32N4/c1-7-17-29-25-15-21-31(27-13-5-3-11-23(25)27)19-9-2-10-20-32-22-16-26(30-18-8-1)24-12-4-6-14-28(24)32/h3-6,11-16,21-22H,1-2,7-10,17-20H2/p+2
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InChIKey |
IOXVWOJJNCBJBX-UHFFFAOYSA-P
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PubChem Compound ID | |||||
PubChem Substance ID | |||||
Target and Pathway | |||||
Target(s) | KCa2.1 | Target Info | Blocker (channel blocker) | [525697] | |
KCa2.3 | Target Info | Blocker (channel blocker) | [526131] | ||
KCa2.2 | Target Info | Blocker (channel blocker) | [526016] | ||
References | |||||
Ref 525697 | The pharmacology of hSK1 Ca2+-activated K+ channels expressed in mammalian cell lines. Br J Pharmacol. 2000 Feb;129(4):627-30. | ||||
Ref 526016 | Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels. J Biol Chem. 2001 Apr 13;276(15):12249-56. Epub 2001 Jan 22. | ||||
Ref 526131 | SK3 is an important component of K(+) channels mediating the afterhyperpolarization in cultured rat SCG neurones. J Physiol. 2001 Sep 1;535(Pt 2):323-34. |
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