Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0R2ES
|
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| Former ID |
DNC011955
|
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| Drug Name |
2-Phenyl-5,6-dihydro-pyrazolo[1,5-c]quinazoline
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C16H13N3
|
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| Canonical SMILES |
C1N=C2C=CC=CC2=C3N1NC(=C3)C4=CC=CC=C4
|
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| InChI |
1S/C16H13N3/c1-2-6-12(7-3-1)15-10-16-13-8-4-5-9-14(13)17-11-19(16)18-15/h1-10,18H,11H2
|
||||
| InChIKey |
PJUDEWJNGXVAML-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Gamma-aminobutyric acid receptor | Target Info | Inhibitor | [1] | |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Retrograde endocannabinoid signaling | |||||
| GABAergic synapse | |||||
| Morphine addiction | |||||
| Nicotine addiction | |||||
| Reactome | Ligand-gated ion channel transport | ||||
| GABA A receptor activation | |||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
| Iron uptake and transport | |||||
| References | |||||
| REF 1 | J Med Chem. 1996 Jul 19;39(15):2915-21.Synthesis and binding activity of some pyrazolo[1,5-c]quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand. | ||||
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