Drug Information
Drug General Information | |||||
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Drug ID |
D0YS9E
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Former ID |
DNC007223
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Drug Name |
4-Phenyl-5-piperidin-4-yl-isoxazol-3-ol
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Synonyms |
4-phenyl-5-(4-piperidyl)-3-isoxazolol
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Indication | Discovery agent | Investigative | [527382] | ||
Structure |
Download2D MOL |
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Target and Pathway | |||||
Target(s) | Gamma-aminobutyric acid receptor | Target Info | Inhibitor | [528744] | |
Gamma-aminobutyric acid receptor subunit gamma-2 | Target Info | Inhibitor | [527382] | ||
Gamma-aminobutyric acid receptor subunit beta-2 | Target Info | Inhibitor | [527382] | ||
Gamma-aminobutyric acid receptor subunit alpha-1 | Target Info | Inhibitor | [527382] | ||
WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
Iron uptake and transportWP706:SIDS Susceptibility Pathways | |||||
Iron uptake and transport | |||||
References | |||||
Ref 527382 | J Med Chem. 2005 Jan 27;48(2):427-39.Potent 4-aryl- or 4-arylalkyl-substituted 3-isoxazolol GABA(A) antagonists: synthesis, pharmacology, and molecular modeling. | ||||
Ref 528744 | J Med Chem. 2007 Apr 19;50(8):1988-92. Epub 2007 Mar 22.4-aryl-5-(4-piperidyl)-3-isoxazolol GABAA antagonists: synthesis, pharmacology, and structure-activity relationships. |
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