Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| Ftase --- FPTase | C-(4-Chloro-phenyl)-C-[5-(3-chloro-phenyl)-imidazo[1,2-a]quinolin-7-yl]-C-(3-methyl-3H-imidazol-4-yl)-methylamine | Drug Info |
| Ftase --- FPTase | 4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cyclohexylamide 2-{[2-(1-methyl-1H-imidazol-4-yl)-ethyl]-amide} | Drug Info |
| Ftase --- FPTase | 3-Biphenyl-4-ylethynyl-4-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-benzonitrile | Drug Info |
| Ftase --- FPTase | 1-[4-(8-Chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-(1-methyl-piperidin-4-yl)-ethanone | Drug Info |
| Ftase --- FPTase | 3-(3-(1H-imidazol-1-yl)propyl)-1-(4-(aminomethyl)benzyl)-5-methyl-5-(naphthalen-1-yl)imidazolidine-2,4-dione | Drug Info |
| Ftase --- FPTase | 4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-2-[(pyridin-3-ylmethyl)-carbamoyl]-piperazine-1-carboxylic acid tert-butyl ester | Drug Info |
| Ftase --- FPTase | 4-{2-[4-(8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazin-1-yl]-2-oxo-ethyl}-piperidine-1-carboxylic acid aminomethyl-amide | Drug Info |
| Ftase --- FPTase | 1-(((2R,3R)-3-(2,4-dichlorobenzyloxy)-5-fluoro-2,3-dihydrobenzo[b]thiophen-2-yl)methyl)-1H-imidazole | Drug Info |
| Ftase --- FPTase | [1-(3H-Imidazol-4-ylmethyl)-4-naphthalen-1-yl-1H-pyrrol-3-yl]-phenyl-methanone | Drug Info |
| Ftase --- FPTase | Biphenyl-2-yl-[1-(3H-imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-methanone | Drug Info |
| Ftase --- FPTase | 4-(5-{[1-(2-Hydroxy-pyridine-3-carbonyl)-pyrrolidin-3-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile | Drug Info |
| Ftase --- FPTase | (S)-2-(3-{[(1H-Imidazol-4-ylmethyl)-(4-methoxy-benzyl)-amino]-methyl}-benzoylamino)-4-methylsulfanyl-butyric acid | Drug Info |
| Ftase --- FPTase | [(S)-4-[2-(3H-Imidazol-4-yl)-ethyl]-3-(2-methoxy-ethyl)-piperazin-1-yl]-naphthalen-1-yl-methanone | Drug Info |
| Ftase --- FPTase | 2-(2,3-Dihydroxy-benzoyl)-6-hydroxy-benzene-1,4-dicarbaldehyde | Drug Info |
| Ftase --- FPTase | 2-[4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-(2-pyridin-4-yl-acetyl)-piperazin-2-yl]-N-cyclopropyl-acetamide | Drug Info |
| Ftase --- FPTase | (R)-2-({4-[((R)-2-Amino-3-mercapto-propylamino)-methyl]-biphenyl-2-carbonyl}-amino)-3-methylsulfanyl-propionic acid | Drug Info |
| Ftase --- FPTase | N-Cyclopentyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-4-ylmethyl-acetamide | Drug Info |
| Ftase --- FPTase | (S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-naphthalene-1-carbothioyl]-amino}-4-methylsulfanyl-butyric acid | Drug Info |
| Ftase --- FPTase | N-(3-chloro-phenyl)-5-cyano-2-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-benzamide | Drug Info |
| Ftase --- FPTase | Lithium; (S)-2-{[2'-methyl-5-(5-pyridin-3-yl-furan-2-ylmethoxymethyl)-biphenyl-2-carbonyl]-amino}-4-methylsulfanyl-butyrate | Drug Info |
| Ftase --- FPTase | 6-[(4'-Chloro-6-cyano-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-1-methyl-2-oxo-5-(4-trifluoromethoxy-phenyl)-1,2-dihydro-pyridine-3-carbonitrile | Drug Info |
| Ftase --- FPTase | 2-[2-(2-Chloro-phenyl)-1H-indol-3-yl]-N-(2-cyano-ethyl)-N-cyclopropyl-acetamide | Drug Info |
| Ftase --- FPTase | 4-{5-[(2-Oxo-3-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ylamino)-methyl]-imidazol-1-ylmethyl}-benzonitrile | Drug Info |
| Ftase --- FPTase | [1-(3-Benzyl-3H-imidazol-4-ylmethyl)-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-naphthalen-1-yl-methanone | Drug Info |
| Ftase --- FPTase | 6-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-3',5'-difluoro-biphenyl-3-carbonitrile | Drug Info |
| Ftase --- FPTase | 1-[4-(8-Chloro-3-methoxy-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-piperidin-1-yl]-2-pyridin-4-yl-ethanone | Drug Info |
| Ftase --- FPTase | (S)-2-((3Z,6E)-(2S,5S,8R)-8-Amino-2-benzyl-5-isopropyl-9-mercapto-nona-3,6-dienoylamino)-4-methylsulfanyl-butyric acid | Drug Info |
| Ftase --- FPTase | 4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperazine-1,2-dicarboxylic acid 1-cyclohexylamide 2-[(3-imidazol-1-yl-propyl)-amide] 1-cycloheptylamide 2-[(pyridin-3-ylmethyl)-amide] | Drug Info |
| Ftase --- FPTase | (S)-2-[(5-{[(1H-Imidazol-4-ylmethyl)-amino]-methyl}-2'-methyl-biphenyl-2-carbonyl)-amino]-4-methylsulfanyl-butyric acid | Drug Info |
| Ftase --- FPTase | 4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-1-pentanoyl-piperazine-2-carboxylic acid pyridin-3-ylamide | Drug Info |
| Ftase --- FPTase | 1-[(S)-4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-2-(2-methoxy-ethyl)-piperazin-1-yl]-2-piperidin-4-yl-ethanone | Drug Info |
| Ftase --- FPTase | 4-(5-{[3-(3-Bromo-benzyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[d]azepin-1-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile | Drug Info |
| Ftase --- FPTase | 5-cyano-2-(((4-cyanophenyl)(1-methyl-1H-imidazol-5-yl)methoxy)methyl)-N-phenylbenzamide | Drug Info |
| Ftase --- FPTase | 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyano-N'-(1-oxy-pyridin-4-ylmethyl)-piperidine-1-carboxamidine | Drug Info |
| Ftase --- FPTase | 4-(3-Bromo-8-chloro-5,6-dihydro-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-N-cyclopropyl-N'-cyano-piperidine-1-carboxamidine | Drug Info |
| Ftase --- FPTase | N-Isopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyrazin-2-ylmethyl-acetamide | Drug Info |
| Ftase --- FPTase | N-[6-Cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-benzenesulfonamide | Drug Info |
| Ftase --- FPTase | 4-[3-(4-Cyano-benzyl)-3H-imidazol-4-ylmethyl]-piperazine-1-carboxylic acid 2-trifluoromethoxy-benzyl ester | Drug Info |
| Ftase --- FPTase | (E)-3-Carboxy-2-(16-sulfooxy-hexadecyl)-pent-2-enedioic acid | Drug Info |
| Ftase --- FPTase | N-Isopropyl-2-(2-phenyl-1H-indol-3-yl)-N-pyridin-3-ylmethyl-acetamide | Drug Info |
| Ftase --- FPTase | (R)-2-({(R)-2-[(R)-2-((S)-2-Amino-3-mercapto-propionylamino)-3-methyl-butyryl]-1,2,3,4-tetrahydro-isoquinolin-3-ylmethyl}-amino)-4-methylsulfanyl-butyric acid | Drug Info |
| Ftase --- FPTase | N-[6-Cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-N-cyclohexylmethyl-benzenesulfonamide | Drug Info |
| Ftase --- FPTase | 1-{2-[3-(3-Chloro-4-cyano-benzyl)-3H-imidazol-4-yl]-acetyl}-5-naphthalen-1-yl-1,2,3,6-tetrahydro-pyridine-4-carbonitrile | Drug Info |
| Ftase --- FPTase | 5-((3-(3-(1H-imidazol-1-yl)propyl)-5-methyl-5-(naphthalen-1-yl)-2,4-dioxoimidazolidin-1-yl)methyl)-2-(methylsulfonyl)benzonitrile | Drug Info |
| Ftase --- FPTase | 4'-(3-Mercapto-propionylamino)-[1,1';2',1'']terphenyl-3-carboxylic acid 37 (FTI-2317) | Drug Info |
| Ftase --- FPTase | 4-(5-{[1-(2-Amino-pyridine-3-carbonyl)-pyrrolidin-3-ylamino]-methyl}-imidazol-1-ylmethyl)-benzonitrile | Drug Info |
| Ftase --- FPTase | Acetic acid 2-acetoxy-6-(3-acetoxy-2,5-diformyl-benzoyl)-phenyl ester | Drug Info |
| Ftase --- FPTase | Lithium; (S)-2-({5-[5-(4-chloro-3-fluoro-phenyl)-furan-2-ylmethoxymethyl]-2'-methyl-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyrate | Drug Info |
| Ftase --- FPTase | Pyridine-3-sulfonic acid [6-cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-thiophen-3-ylmethyl-amide | Drug Info |
| Ftase --- FPTase | (S)-2-({5-[2-((E)-4-Chloro-pyridin-3-yl)-vinyl]-2'-methyl-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyric acid | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.