Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CABL --- MCSF | Imatinib | Drug Info |
| CAI --- CAIX | BENZOLAMIDE | Drug Info |
| Aurora --- VEGFR | 7-(5-(2-(piperidin-1-yl)ethoxy)-1H-indol-2-yl)isoindolin-1-one | Drug Info |
| AuroraA --- STK1 | N-(6-(4-fluorophenylthio)-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-yl)-3-methylisothiazol-5-amine | Drug Info |
| AuroraA --- STK1 | 1-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)-3-(3-(trifluoromethyl)phenyl)urea | Drug Info |
| AuroraA --- STK1 | CHEMBL216053 | Drug Info |
| AuroraA --- STK1 | 6-Methyl-N-[3-[[(2,2,3,3,3-pentafluoropropyl)amino]methyl]-5-isothiazolyl]-3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-8-amine Hydrochloride | Drug Info |
| AuroraA --- STK1 | CHEMBL215322 | Drug Info |
| AuroraA --- STK1 | N-Cyclopropyl-4-(5-fluoro-2-(4-hydroxyphenylamino)pyrimidin-4-ylamino)benzamide | Drug Info |
| AuroraA --- STK1 | N-Ethyl-N'-[4-(1-ethyl-4-{2-[4-(1-pyrrolidinylmethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-1H-pyrazol-3-yl)phenyl]urea | Drug Info |
| AuroraA --- STK1 | 1-(3-chloro-4-fluorophenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea | Drug Info |
| AuroraA --- STK1 | CHEMBL381724 | Drug Info |
| CDK1 --- Cyclin E | PHENYLAMINOIMIDAZO(1,2-ALPHA)PYRIDINE | Drug Info |
| Beta PDGFR --- Ckit | 4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazolin-4-yl]-piperazine-1-carbothioic acid pyridin-4-ylamide | Drug Info |
| BNOS --- Hepatocyte NOS | 2-Imino-4-methyl-5-pentyl-pyrrolidin-3-ol | Drug Info |
| BNOS --- Hepatocyte NOS | (R,E)-3-propyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine | Drug Info |
| BNOS --- Hepatocyte NOS | 2-Methyl-isothiourea | Drug Info |
| BNOS --- Hepatocyte NOS | 2-(2-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)pyrrolidin-1-yl)-N-(benzo[d][1,3]dioxol-5-ylmethyl)-N-methylethanamine | Drug Info |
| BNOS --- Hepatocyte NOS | 4-chloro-2-((isobutyl(piperidin-4-yl)amino)methyl)benzonitrile | Drug Info |
| BNOS --- Hepatocyte NOS | 2,7-dinitro-2H-indazole | Drug Info |
| BNOS --- Hepatocyte NOS | 1-(2-Bromo-phenyl)-2-ethyl-isothiourea | Drug Info |
| BNOS --- Hepatocyte NOS | 6-{4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-naphthalen-1-yl}-pyridin-2-ylamine | Drug Info |
| BNOS --- Hepatocyte NOS | 4-((2-(3,3-Difluorocyclobutyl)-1H-imidazo[4,5-b]pyrazin-1-yl)-methyl)-8-fluoroquinolin-2(1H)-one | Drug Info |
| CABL --- PKCA | N-(3-chlorophenyl)-4-(pyridin-3-yl)pyrimidin-2-amine | Drug Info |
| 5HT1a --- SERT | (S)-1-[(2S,4R)-4-(5-Chloro-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(2-methyl-1H-indol-4-yloxy)-propan-2-ol | Drug Info |
| 5HT1a --- SERT | (S)-1-(1H-indol-4-yloxy)-3-((2S,4R)-4-(6-methoxybenzo[b]thiophen-2-yl)-2-methylpiperidin-1-yl)propan-2-ol | Drug Info |
| 5HT1a --- SERT | 6-((1-(2-(8-chloro-2-methylquinolin-5-yloxy)ethyl)piperidin-4-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one | Drug Info |
| 5HT1b --- SERT | (1R)-1-(2-((S)-4-(6-cyanonaphthalen-1-yl)-2-methylpiperazin-1-yl)ethyl)-1,3,7,7a-tetrahydroisobenzofuran-5-carboxamide | Drug Info |
| ABL --- FGFR | 3-(4-(1H-pyrazolo[3,4-b]pyridin-5-yl)-1H-1,2,3-triazol-1-yl)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide | Drug Info |
| ADRA1A --- HRH1 | SID104171359 | Drug Info |
| ADRA1A --- HRH1 | 2-Ethyl-10-(4-methyl-piperazin-1-yl)-4H-3-thia-4,9-diaza-benzo[f]azulene | Drug Info |
| ADRA1A --- HRH1 | 2-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione | Drug Info |
| CABL --- Ckit | PHA-739358 | Drug Info |
| CABL --- STK1 | Dasatinib | Drug Info |
| Aurora --- GSK | 4-(3-Adamantan-1-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-ylamino)-benzoic acid | Drug Info |
| AuroraA --- CD135 | N1-[3-(5-[6-(4-Hydroxypiperidino)-2-methyl-4-pyrimidinyl]amino-1H-3-pyrazolyl)phenyl]-1-benzenesulfonamide | Drug Info |
| AuroraA --- STK1 | 3-fluoro-N-({2-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propoxy}-6-methoxyquinazolin-4-yl)amino]-1,3-thiazol-5-yl}methyl)-benzamide | Drug Info |
| AuroraA --- STK1 | 5-(pyridin-4-yl)-6-(pyrrolidin-1-yl)-3-styryl-1H-indazole | Drug Info |
| AuroraA --- STK1 | K00001 | Drug Info |
| AuroraA --- STK1 | N2-(4-(benzo[d]thiazol-2-yl)-3-methoxyphenyl)-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine | Drug Info |
| AuroraA --- STK1 | (Z)-N-[3-({3-[3-(Diethylamino)propyl]-4-oxo-4,5,6,7-tetrahydro-1H-indol-2-yl}methylene)-2-oxoindolin-5-yl]benzenesulfonamide | Drug Info |
| AuroraA --- STK1 | (Z)-3-(4-Oxo-2-{[2-oxo-5-(phenylsulfonamido)indolin-3-ylidene]-methyl}-4,5,6,7-tetrahydro-1H-indol-3-yl)propanoic Acid | Drug Info |
| AuroraA --- STK1 | 4-(2-(4-(2-(4-Acetylpiperazin-1-yl)-2-oxoethyl)phenylamino)-5-fluoropyrimidin-4-ylamino)-N-(2-chlorophenyl)benzamide | Drug Info |
| AuroraA --- STK1 | 1-phenyl-N-(3-styryl-1H-indazol-5-yl)methanesulfonamide | Drug Info |
| Beta PDGFR --- CABL | 4-fluoro-N-(3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenyl)benzamide | Drug Info |
| Beta PDGFR --- Ckit | 4-[6-Methoxy-7-(2-piperidin-1-yl-ethoxy)-quinazolin-4-yl]-piperazine-1-carbothioic acid (6-chloro-pyridin-3-yl)-amide | Drug Info |
| BNOS --- Hepatocyte NOS | N-(4-{[3-(1-Imino-ethyl)-benzylamino]-methyl}-phenyl)-acetamidine | Drug Info |
| BNOS --- Hepatocyte NOS | 5-Ethyl-4-methyl-pyridin-2-ylamine | Drug Info |
| BNOS --- Hepatocyte NOS | 7-Methyl-2,3,3a,9b-tetrahydro-1H-cyclopenta[c]quinolin-4-ylamine | Drug Info |
| BNOS --- Hepatocyte NOS | 4-(((3-chlorophenyl)(pyrimidin-5-yl)amino)methyl)-7,8-difluoroquinolin-2(1H)-one | Drug Info |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.