Drug Information
Drug General Information | Top | |||
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Drug ID |
D05BCJ
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Former ID |
DNC003883
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Drug Name |
1-Benzyl-4-pyrrol-1-yl-piperidine
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Synonyms |
1-benzyl-4-(1H-pyrrol-1-yl)piperidine; 254115-91-8; CHEMBL326877; 1-(phenylmethyl)-4-pyrrol-1-yl-piperidine; 1-benzyl-4-pyrrolylpiperidine; 1-benzyl-4-pyrrol-1-yl-piperidine; AC1MCV5B; AC1Q28X7; CTK5J6306; KS-00003TOT; MolPort-001-764-445; ZINC161500; 1-benzyl-4-pyrrol-1-ylpiperidine; BDBM50082169; SBB056067; 1-benzyl-4-(pyrrol-1-yl)piperidine; AKOS008965823; NE54439; MCULE-3402690429; TS-03355; 1-Benzyl-4-(1H-pyrrole-1-yl)piperidine; KB-152224; ST50950067; EN300-52430; Z56618096
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H20N2
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Canonical SMILES |
C1CN(CCC1N2C=CC=C2)CC3=CC=CC=C3
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InChI |
1S/C16H20N2/c1-2-6-15(7-3-1)14-17-12-8-16(9-13-17)18-10-4-5-11-18/h1-7,10-11,16H,8-9,12-14H2
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InChIKey |
UPRFZLANTXURKF-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Dopamine D2 receptor (D2R) | Target Info | Inhibitor | [1] |
Dopamine D3 receptor (D3R) | Target Info | Inhibitor | [1] | |
Dopamine D4 receptor (D4R) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Rap1 signaling pathway | |||
cAMP signaling pathway | ||||
Neuroactive ligand-receptor interaction | ||||
Gap junction | ||||
Dopaminergic synapse | ||||
Parkinson's disease | ||||
Cocaine addiction | ||||
Alcoholism | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
Dopamine receptor mediated signaling pathway | ||||
Nicotine pharmacodynamics pathway | ||||
Reactome | Dopamine receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | Hypothetical Network for Drug Addiction | |||
Monoamine GPCRs | ||||
GPCRs, Class A Rhodopsin-like | ||||
Genes and (Common) Pathways Underlying Drug Addiction | ||||
GPCR ligand binding | ||||
GPCR downstream signaling | ||||
Nicotine Activity on Dopaminergic Neurons | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | Piperidinylpyrroles: design, synthesis and binding properties of novel and selective dopamine D4 receptor ligands. Bioorg Med Chem Lett. 1999 Nov 1;9(21):3143-6. |
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