Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08BCF
|
|||
| Former ID |
DNC003554
|
|||
| Drug Name |
QUIPAZINE
|
|||
| Synonyms |
quipazine; 4774-24-7; 2-(piperazin-1-yl)quinoline; 2-Piperazin-1-yl-quinoline; 2-Piperazin-1-ylquinoline; Quinoline, 2-(1-piperazinyl)-; 2-(1-Piperazinyl)quinoline; Quipazine [INN]; 1-(2-Quinolinyl)piperazine; Quipazinum [INN-Latin]; Quipazina [INN-Spanish]; UNII-4WCY05C0SJ; 1-(2-Quinolyl)piperazine; 2-(1-Piperazinyl)chinolin; BRN 0196945; 4WCY05C0SJ; CHEMBL18772; 2-quinolylpiperazine; F3306-0004; Quipazinum; Quipazina; TPC-A004; MA-1291; Spectrum_001733; Tocris-0629; piperazin-1-yl-quinoline; AC1L1JEX; AC1Q4WAV; Spectrum4_001259
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C13H15N3
|
|||
| Canonical SMILES |
C1CN(CCN1)C2=NC3=CC=CC=C3C=C2
|
|||
| InChI |
1S/C13H15N3/c1-2-4-12-11(3-1)5-6-13(15-12)16-9-7-14-8-10-16/h1-6,14H,7-10H2
|
|||
| InChIKey |
XRXDAJYKGWNHTQ-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 4774-24-7
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
3944551, 5198891, 8153084, 11111709, 11111710, 11113608, 11336086, 11361325, 11364627, 11367189, 11369751, 11373066, 11374956, 11377913, 11462297, 11466645, 11467765, 11484959, 11486509, 11488998, 11491639, 11493073, 11495547, 15195795, 26751806, 29224083, 47291201, 47365258, 47365259, 47365260, 47440334, 47662348, 48110510, 48110511, 48185060, 48259305, 49698965, 50043052, 50104499, 50760391, 56242155, 57322565, 81053885, 81100224, 85209659, 85788303, 85789362, 85789752, 87363377, 99300411
|
|||
| ChEBI ID |
CHEBI:93368
|
|||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 173). | |||
| REF 2 | Novel, potent, and selective quinoxaline-based 5-HT(3) receptor ligands. 1. Further structure-activity relationships and pharmacological characteri... J Med Chem. 2009 Nov 12;52(21):6946-50. | |||
| REF 3 | 5-HT1 and 5-HT2 binding characteristics of some quipazine analogues. J Med Chem. 1986 Nov;29(11):2375-80. | |||
| REF 4 | Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy ... J Med Chem. 1999 May 6;42(9):1556-75. | |||
| REF 5 | Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). J Med Chem. 2003 Jul 3;46(14):2795-812. | |||
| REF 6 | Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 1. Bioorg Med Chem Lett. 2000 Jul 17;10(14):1559-62. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.