Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0SP2J
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| Former ID |
DIB019034
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| Drug Name |
bufotenine
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| Synonyms |
DM5-HT; dimethylserotonin; N,N-dimethyl-5-HT; N,N-dimethylserotonin; 5-OH-DMT
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C12H16N2O
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| Canonical SMILES |
CN(C)CCC1=CNC2=C1C=C(C=C2)O
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| InChI |
1S/C12H16N2O/c1-14(2)6-5-9-8-13-12-4-3-10(15)7-11(9)12/h3-4,7-8,13,15H,5-6H2,1-2H3
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| InChIKey |
VTTONGPRPXSUTJ-UHFFFAOYSA-N
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| CAS Number |
CAS 487-93-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
10497, 396834, 595001, 6308314, 8157399, 10523919, 12015261, 14822340, 29228776, 46507174, 46530531, 47440788, 47589506, 47885916, 49984707, 50413991, 57326082, 58005029, 85209815, 94524805, 103172929, 103934497, 104322802, 124954092, 126579212, 126736670, 129525791, 131727789, 134973156, 135584581, 135650030, 137002805, 144206443, 160964711, 162159006, 162955505, 164807342, 179226198, 184585265, 198955790, 203093598, 206256315, 226830471, 249924472
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| ChEBI ID |
CHEBI:3210
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 144). | |||
| REF 2 | Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamine and [3H]alniditan. Mol Pharmacol. 1996 Dec;50(6):1567-80. | |||
| REF 3 | Mapping the binding site pocket of the serotonin 5-Hydroxytryptamine2A receptor. Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin. J Biol Chem. 1996 Jun 21;271(25):14672-5. | |||
| REF 4 | Expression of functional mouse 5-HT5A serotonin receptor in the methylotrophic yeast Pichia pastoris: pharmacological characterization and localization. FEBS Lett. 1995 Dec 27;377(3):451-6. | |||
| REF 5 | Functional and radioligand binding characterization of rat 5-HT6 receptors stably expressed in HEK293 cells. Neuropharmacology. 1997 Apr-May;36(4-5):713-20. | |||
| REF 6 | Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase. Mol Pharmacol. 1993 Aug;44(2):229-36. | |||
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