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| Protein General Information (TTD Target) |
Top |
| Full Name |
Interferon alpha/beta receptor 2 (IFNAR2)
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Successful
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Target Info
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| UniProt ID |
INAR2_HUMAN
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| Gene Name |
IFNAR2
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| Gene ID |
3455
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| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Janus kinase 1 (JAK-1) |
Target Info
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PPI Info
|
[1] |
| Interacting Clinical trial Target(s) |
Interferon alpha/beta receptor 1 (IFNAR1) |
Target Info
|
PPI Info
|
[2] |
| Interacting Literature-reported Target(s) |
Receptor of activated protein C kinase 1 (RACK1) |
Target Info
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PPI Info
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[3] |
| References |
Top |
| REF 1 |
UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity. EMBO J. 2006 Jun 7;25(11):2358-67.
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| REF 2 |
A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses. Cell Rep. 2013 Oct 17;5(1):180-93.
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| REF 3 |
Receptor for activated C-kinase (RACK-1), a WD motif-containing protein, specifically associates with the human type I IFN receptor. J Immunol. 2000 Nov 1;165(9):5127-32.
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