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| Protein General Information (TTD Target) |
Top |
| Full Name |
Leucine-rich repeat kinase 2 (LRRK2)
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Clinical trial
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Target Info
|
| UniProt ID |
LRRK2_HUMAN
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| Gene Name |
LRRK2
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| Gene ID |
120892
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| References |
Top |
| REF 1 |
14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization. Biochem J. 2010 Sep 15;430(3):393-404.
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| REF 2 |
Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila. EMBO J. 2008 Sep 17;27(18):2432-43.
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| REF 3 |
Identification of potential protein interactors of Lrrk2. Parkinsonism Relat Disord. 2007 Oct;13(7):382-5.
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| REF 4 |
MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2. J Neurochem. 2010 Mar;112(6):1593-604.
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