| References |
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| REF 1 |
A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein. Mol Cell Proteomics. 2010 Feb;9(2):255-70.
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| REF 2 |
Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5. Proteomics. 2011 Apr;11(8):1508-16.
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| REF 3 |
CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism. Hum Mol Genet. 2007 Apr 1;16(7):848-64.
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| REF 4 |
Differential impact of tetratricopeptide repeat proteins on the steroid hormone receptors. PLoS One. 2010 Jul 22;5(7):e11717.
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| REF 5 |
C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances. Oncogene. 2013 Jun 20;32(25):3101-10.
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| REF 6 |
The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding. Nat Commun. 2016 Jun 29;7:12037.
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| REF 7 |
Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays. Mol Cell Proteomics. 2006 Feb;5(2):234-44.
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| REF 8 |
Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex. Mol Cell. 2005 Nov 23;20(4):525-38.
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| REF 9 |
Molecular mechanism of the negative regulation of Smad1/5 protein by carboxyl terminus of Hsc70-interacting protein (CHIP). J Biol Chem. 2011 May 6;286(18):15883-94.
|
| REF 10 |
Structural and functional coupling of Hsp90- and Sgt1-centred multi-protein complexes. EMBO J. 2008 Oct 22;27(20):2789-98.
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| REF 11 |
Expansion of protein interaction maps by phage peptide display using MDM2 as a prototypical conformationally flexible target protein. J Mol Biol. 2004 Mar 12;337(1):129-45.
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| REF 12 |
Co-chaperone FKBP38 promotes HERG trafficking. J Biol Chem. 2007 Aug 10;282(32):23509-16.
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| REF 13 |
Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins. Cardiovasc Res. 2013 Dec 1;100(3):520-8.
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| REF 14 |
A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors. Cell Death Differ. 2013 Oct;20(10):1306-16.
|
| REF 15 |
HDAC6 modulates Hsp90 chaperone activity and regulates activation of aryl hydrocarbon receptor signaling. J Biol Chem. 2009 Mar 20;284(12):7436-45.
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| REF 16 |
HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor. Mol Cell. 2005 May 27;18(5):601-7.
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| REF 17 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell. 2015 Oct 22;163(3):712-23.
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| REF 18 |
Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function. Mol Cell. 2010 Feb 12;37(3):333-43.
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| REF 19 |
Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2937-42.
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| REF 20 |
Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors. Mol Cell. 2014 Jan 23;53(2):317-29.
|
| REF 21 |
Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors. Cell Rep. 2016 Feb 2;14(4):872-884.
|
| REF 22 |
Middle domain of human Hsp90 isoforms differentially binds Aha1 in human cells and alters Hsp90 activity in yeast. Biochim Biophys Acta. 2015 Feb;1853(2):445-52.
|
| REF 23 |
Oxidative inhibition of Hsp90 disrupts the super-chaperone complex and attenuates pancreatic adenocarcinoma in vitro and in vivo. Int J Cancer. 2013 Feb 1;132(3):695-706.
|
| REF 24 |
The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37). Cell. 2004 Jan 9;116(1):87-98.
|
| REF 25 |
Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins. Biochim Biophys Acta. 2012 Jun;1823(6):1092-101.
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| REF 26 |
Identification and characterization of Harc, a novel Hsp90-associating relative of Cdc37. J Biol Chem. 2001 Aug 17;276(33):30971-9.
|
| REF 27 |
A truncated form of p23 down-regulates telomerase activity via disruption of Hsp90 function. J Biol Chem. 2009 Nov 6;284(45):30871-80.
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| REF 28 |
Protein phosphatase 5 is a major component of glucocorticoid receptor.hsp90 complexes with properties of an FK506-binding immunophilin. J Biol Chem. 1997 Jun 27;272(26):16224-30.
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| REF 29 |
A high-throughput approach for measuring temporal changes in the interactome. Nat Methods. 2012 Sep;9(9):907-9.
|
| REF 30 |
Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sep 17;525(7569):339-44.
|
| REF 31 |
A proteomic snapshot of the human heat shock protein 90 interactome. FEBS Lett. 2005 Nov 21;579(28):6350-4.
|
| REF 32 |
Nucleotide binding states of hsp70 and hsp90 during sequential steps in the process of glucocorticoid receptor.hsp90 heterocomplex assembly. J Biol Chem. 2002 Sep 13;277(37):33698-703.
|
| REF 33 |
Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system. EMBO J. 2003 Jul 15;22(14):3613-23.
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| REF 34 |
The enhancement of antiproliferative and proapoptotic activity of HDAC inhibitors by curcumin is mediated by Hsp90 inhibition. Cell Mol Life Sci. 2010 Mar;67(6):995-1004.
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| REF 35 |
Interaction of Hsp90 with ribosomal proteins protects from ubiquitination and proteasome-dependent degradation. Mol Biol Cell. 2006 Feb;17(2):824-33.
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| REF 36 |
VCP/p97 AAA-ATPase does not interact with the endogenous wild-type cystic fibrosis transmembrane conductance regulator. Am J Respir Cell Mol Biol. 2007 Jun;36(6):706-14.
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| REF 37 |
FKBP51 promotes assembly of the Hsp90 chaperone complex and regulates androgen receptor signaling in prostate cancer cells. Mol Cell Biol. 2010 Mar;30(5):1243-53.
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| REF 38 |
Molecular imaging of the efficacy of heat shock protein 90 inhibitors in living subjects. Cancer Res. 2008 Jan 1;68(1):216-26.
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| REF 39 |
Celastrol inhibits Hsp90 chaperoning of steroid receptors by inducing fibrillization of the Co-chaperone p23. J Biol Chem. 2010 Feb 5;285(6):4224-31.
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| REF 40 |
Intracellular dynamics of the Hsp90 co-chaperone p23 is dictated by Hsp90. Exp Cell Res. 2006 Jan 15;312(2):198-204.
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| REF 41 |
Stimulation of the weak ATPase activity of human hsp90 by a client protein. J Mol Biol. 2002 Jan 25;315(4):787-98.
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| REF 42 |
Crystal structure and activity of human p23, a heat shock protein 90 co-chaperone. J Biol Chem. 2000 Jul 28;275(30):23045-52.
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| REF 43 |
Localization of sites of interaction between p23 and Hsp90 in solution. J Biol Chem. 2006 May 19;281(20):14457-64.
|
| REF 44 |
In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis. J Cell Biol. 1998 Nov 16;143(4):901-10.
|
| REF 45 |
Toward an understanding of the protein interaction network of the human liver. Mol Syst Biol. 2011 Oct 11;7:536.
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| REF 46 |
Quantitative assessment of complex formation of nuclear-receptor accessory proteins. Biochem J. 2000 Feb 1;345 Pt 3:627-36.
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| REF 47 |
S100 proteins regulate the interaction of Hsp90 with Cyclophilin 40 and FKBP52 through their tetratricopeptide repeats. FEBS Lett. 2010 Mar 19;584(6):1119-25.
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| REF 48 |
Identification of cyclophilin-40-interacting proteins reveals potential cellular function of cyclophilin-40. Anal Biochem. 2011 Mar 15;410(2):257-65.
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| REF 49 |
The Bcl-2 regulator FKBP38-calmodulin-Ca2+ is inhibited by Hsp90. J Biol Chem. 2007 May 25;282(21):15341-8.
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| REF 50 |
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90. EMBO J. 2006 Oct 18;25(20):5015-25.
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| REF 51 |
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Cell. 2012 Aug 31;150(5):987-1001.
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| REF 52 |
An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humans. Nat Commun. 2017 May 24;8:15328.
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| REF 53 |
Hydroxamic acid analogue histone deacetylase inhibitors attenuate estrogen receptor-alpha levels and transcriptional activity: a result of hyperacetylation and inhibition of chaperone function of heat shock protein 90. Clin Cancer Res. 2007 Aug 15;13(16):4882-90.
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| REF 54 |
Gene and protein expression profiling of human ovarian cancer cells treated with the heat shock protein 90 inhibitor 17-allylamino-17-demethoxygeldanamycin. Cancer Res. 2007 Apr 1;67(7):3239-53.
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| REF 55 |
Chaperoning checkpoint kinase 1 (Chk1), an Hsp90 client, with purified chaperones. J Biol Chem. 2006 Feb 3;281(5):2989-98.
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| REF 56 |
Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90. J Biol Chem. 2001 Feb 2;276(5):3702-8.
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| REF 57 |
Blockade of Her2/neu binding to Hsp90 by emodin azide methyl anthraquinone derivative induces proteasomal degradation of Her2/neu. Mol Pharm. 2011 Oct 3;8(5):1687-97.
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| REF 58 |
Regulation of telomerase activity and anti-apoptotic function by protein-protein interaction and phosphorylation. FEBS Lett. 2003 Feb 11;536(1-3):180-6.
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| REF 59 |
HAX-1 Protects Glioblastoma Cells from Apoptosis through the Akt1 Pathway. Front Cell Neurosci. 2017 Dec 21;11:420.
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| REF 60 |
Hematopoietic Substrate-1-Associated Protein X-1 Regulates the Proliferation and Apoptosis of Endothelial Progenitor Cells Through Akt Pathway Modulation. Stem Cells. 2018 Mar;36(3):406-419.
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| REF 61 |
Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase. Cell Signal. 2011 Nov;23(11):1824-30.
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| REF 62 |
Interaction of Hsp90 with the nascent form of the mutant epidermal growth factor receptor EGFRvIII. J Biol Chem. 2003 Feb 14;278(7):5292-9.
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| REF 63 |
Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy. EMBO J. 2002 May 15;21(10):2407-17.
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| REF 64 |
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat Methods. 2014 May;11(5):585-92.
|
| REF 65 |
In silico prediction of physical protein interactions and characterization of interactome orphans. Nat Methods. 2015 Jan;12(1):79-84.
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| REF 66 |
Bcr-Abl ubiquitination and Usp9x inhibition block kinase signaling and promote CML cell apoptosis. Blood. 2011 Mar 17;117(11):3151-62.
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| REF 67 |
Bag1 directly routes immature BCR-ABL for proteasomal degradation. Blood. 2010 Nov 4;116(18):3582-92.
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| REF 68 |
IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol 3'-kinase/Akt, heat shock protein 90, and mammalian target of rapamycin in transformed NK cells. J Immunol. 2005 May 1;174(9):5261-9.
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| REF 69 |
Functional requirement of p23 and Hsp90 in telomerase complexes. Genes Dev. 1999 Apr 1;13(7):817-26.
|
| REF 70 |
Critical regulation of TGFbeta signaling by Hsp90. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9244-9.
|
| REF 71 |
HILI inhibits TGF- signaling by interacting with Hsp90 and promoting TR degradation. PLoS One. 2012;7(7):e41973.
|
| REF 72 |
14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization. Biochem J. 2010 Sep 15;430(3):393-404.
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| REF 73 |
Regulation of LRRK2 stability by the E3 ubiquitin ligase CHIP. PLoS One. 2009 Jun 17;4(6):e5949.
|
| REF 74 |
Signal transduction protein array analysis links LRRK2 to Ste20 kinases and PKC zeta that modulate neuronal plasticity. PLoS One. 2010 Oct 7;5(10):e13191.
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| REF 75 |
Profiling the interactome of protein kinase C by proteomics and bioinformatics. Proteome Sci. 2018 Feb 26;16:5.
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| REF 76 |
A human MAP kinase interactome. Nat Methods. 2010 Oct;7(10):801-5.
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| REF 77 |
Inhibition of histone deacetylase activity suppresses IFN- induction of tripartite motif 22 via CHIP-mediated proteasomal degradation of IRF-1. J Immunol. 2013 Jul 1;191(1):464-71.
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| REF 78 |
HSP90 is necessary for the ACK1-dependent phosphorylation of STAT1 and STAT3. Cell Signal. 2017 Nov;39:9-17.
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| REF 79 |
Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. Sci Signal. 2015 Apr 28;8(374):ra40.
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| REF 80 |
Heat shock protein 90 inhibition depletes TrkA levels and signaling in human acute leukemia cells. Mol Cancer Ther. 2010 Aug;9(8):2232-42.
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| REF 81 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
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| REF 82 |
Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN. EMBO Rep. 2006 Oct;7(10):1023-9.
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| REF 83 |
Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation. J Biol Chem. 2013 Jun 14;288(24):17481-94.
|
| REF 84 |
Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3beta. Biochim Biophys Acta. 2009 Oct;1793(10):1597-603.
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| REF 85 |
Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage. Mol Cancer Ther. 2011 Jul;10(7):1194-206.
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| REF 86 |
Interaction between casein kinase II and the 90-kDa stress protein, HSP90. Biochemistry. 1995 Jun 27;34(25):8123-9.
|
| REF 87 |
Regulation of Pim-1 by Hsp90. Biochem Biophys Res Commun. 2001 Mar 2;281(3):663-9.
|
| REF 88 |
Hsp90 regulates activation of interferon regulatory factor 3 and TBK-1 stabilization in Sendai virus-infected cells. Mol Biol Cell. 2006 Mar;17(3):1461-71.
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| REF 89 |
Hsp90/p50cdc37 is required for mixed-lineage kinase (MLK) 3 signaling. J Biol Chem. 2004 May 7;279(19):19457-63.
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| REF 90 |
The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR. EMBO J. 2001 Jul 16;20(14):3771-80.
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| REF 91 |
Arsenic trioxide exerts antimyeloma effects by inhibiting activity in the cytoplasmic substrates of histone deacetylase 6. PLoS One. 2012;7(2):e32215.
|
| REF 92 |
Hsp90 regulates processing of NF-kappa B2 p100 involving protection of NF-kappa B-inducing kinase (NIK) from autophagy-mediated degradation. Cell Res. 2007 Jun;17(6):520-30.
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| REF 93 |
The E3 ubiquitin ligase MID1 catalyzes ubiquitination and cleavage of Fu. J Biol Chem. 2014 Nov 14;289(46):31805-17.
|
| REF 94 |
Fused kinase is stabilized by Cdc37/Hsp90 and enhances Gli protein levels. Biochem Biophys Res Commun. 2006 Dec 8;351(1):78-84.
|
| REF 95 |
The pro-apoptotic protein death-associated protein 3 (DAP3) interacts with the glucocorticoid receptor and affects the receptor function. Biochem J. 2000 Aug 1;349 Pt 3:885-93.
|
| REF 96 |
Ligand-specific glucocorticoid receptor activation in human platelets. Blood. 2005 Dec 15;106(13):4167-75.
|
| REF 97 |
A tyrosine kinase-dependent pathway regulates ligand-dependent activation of the dioxin receptor in human keratinocytes. J Biol Chem. 1994 Sep 23;269(38):23800-7.
|
| REF 98 |
Evidence that the beta-isoform of the human glucocorticoid receptor does not act as a physiologically significant repressor. J Biol Chem. 1997 Oct 17;272(42):26659-64.
|
| REF 99 |
A cellular factor stimulates ligand-dependent release of hsp90 from the basic helix-loop-helix dioxin receptor. Mol Cell Biol. 1994 Apr;14(4):2438-46.
|
| REF 100 |
Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen. Oncogene. 2014 Jun 26;33(26):3441-50.
|
| REF 101 |
Heat shock protein-90 (Hsp90) acts as a repressor of peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARbeta activity. Biochemistry. 2003 Sep 16;42(36):10726-35.
|
| REF 102 |
Cooperative interactions between androgen receptor (AR) and heat-shock protein 27 facilitate AR transcriptional activity. Cancer Res. 2007 Nov 1;67(21):10455-65.
|
| REF 103 |
Association of the 90-kDa heat shock protein does not affect the ligand-binding ability of androgen receptor. J Steroid Biochem Mol Biol. 1992 Sep;42(8):803-12.
|
| REF 104 |
A novel variant of the putative demethylase gene, s-JMJD1C, is a coactivator of the AR. Arch Biochem Biophys. 2007 Apr 1;460(1):56-66.
|
| REF 105 |
Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor. Biochem J. 2014 Feb 15;458(1):95-107.
|
| REF 106 |
The tale of two domains: proteomics and genomics analysis of SMYD2, a new histone methyltransferase. Mol Cell Proteomics. 2008 Mar;7(3):560-72.
|
| REF 107 |
Proteomic analyses of the SMYD family interactomes identify HSP90 as a novel target for SMYD2. J Mol Cell Biol. 2011 Oct;3(5):301-8.
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| REF 108 |
Novel complexes of guanylate cyclase with heat shock protein 90 and nitric oxide synthase. Am J Physiol Heart Circ Physiol. 2003 Aug;285(2):H669-78.
|
| REF 109 |
Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells. J Biol Chem. 2001 Aug 31;276(35):32663-9.
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| REF 110 |
Role of heat shock protein 90 in bradykinin-stimulated endothelial nitric oxide release. Gen Pharmacol. 2000 Sep;35(3):165-70.
|
| REF 111 |
Native LDL and minimally oxidized LDL differentially regulate superoxide anion in vascular endothelium in situ. Am J Physiol Heart Circ Physiol. 2002 Aug;283(2):H750-9.
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| REF 112 |
Domain mapping studies reveal that the M domain of hsp90 serves as a molecular scaffold to regulate Akt-dependent phosphorylation of endothelial nitric oxide synthase and NO release. Circ Res. 2002 May 3;90(8):866-73.
|
| REF 113 |
Proteomic analysis of the NOS2 interactome in human airway epithelial cells. Nitric Oxide. 2013 Nov 1;34:37-46.
|
| REF 114 |
Heat shock protein 90 as an endogenous protein enhancer of inducible nitric-oxide synthase. J Biol Chem. 2003 Sep 19;278(38):36953-8.
|
| REF 115 |
Prolyl hydroxylase domain protein 2 (PHD2) binds a Pro-Xaa-Leu-Glu motif, linking it to the heat shock protein 90 pathway. J Biol Chem. 2013 Apr 5;288(14):9662-74.
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| REF 116 |
Defective Tibetan PHD2 binding to p23 links high altitude adaption to altered oxygen sensing. J Biol Chem. 2014 May 23;289(21):14656-65.
|
| REF 117 |
Characterization of the deubiquitinating activity of USP19 and its role in endoplasmic reticulum-associated degradation. J Biol Chem. 2014 Feb 7;289(6):3510-7.
|
| REF 118 |
Cytoplasmic Ubiquitin-Specific Protease 19 (USP19) Modulates Aggregation of Polyglutamine-Expanded Ataxin-3 and Huntingtin through the HSP90 Chaperone. PLoS One. 2016 Jan 25;11(1):e0147515.
|
| REF 119 |
Aberrant interaction between Parkinson disease-associated mutant UCH-L1 and the lysosomal receptor for chaperone-mediated autophagy. J Biol Chem. 2008 Aug 29;283(35):23731-8.
|
| REF 120 |
Insights into links between familial and sporadic Parkinson's disease: physical relationship between UCH-L1 variants and chaperone-mediated autophagy. Autophagy. 2008 Aug;4(6):827-9.
|
| REF 121 |
The stabilization mechanism of mutant-type p53 by impaired ubiquitination: the loss of wild-type p53 function and the hsp90 association. Oncogene. 1999 Oct 28;18(44):6037-49.
|
| REF 122 |
Hsp90 chaperones wild-type p53 tumor suppressor protein. J Biol Chem. 2004 Nov 19;279(47):48836-45.
|
| REF 123 |
A census of human soluble protein complexes. Cell. 2012 Aug 31;150(5):1068-81.
|
| REF 124 |
A human protein-protein interaction network: a resource for annotating the proteome. Cell. 2005 Sep 23;122(6):957-68.
|
| REF 125 |
Chrysin inhibits expression of hypoxia-inducible factor-1alpha through reducing hypoxia-inducible factor-1alpha stability and inhibiting its protein synthesis. Mol Cancer Ther. 2007 Jan;6(1):220-6.
|
| REF 126 |
Aryl hydrocarbon nuclear translocator (ARNT) promotes oxygen-independent stabilization of hypoxia-inducible factor-1alpha by modulating an Hsp90-de... J Biol Chem. 2004 Apr 16;279(16):16128-35.
|
| REF 127 |
Carbon monoxide promotes VEGF expression by increasing HIF-1alpha protein level via two distinct mechanisms, translational activation and stabilization of HIF-1alpha protein. J Biol Chem. 2010 Oct 15;285(42):32116-25.
|
| REF 128 |
Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90. PLoS One. 2010 Jul 27;5(7):e11772.
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| REF 129 |
Hemin, an iron-binding porphyrin, inhibits HIF-1 induction through its binding with heat shock protein 90. Int J Cancer. 2012 Feb 1;130(3):716-27.
|
| REF 130 |
Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants. PLoS One. 2015 Oct 30;10(10):e0141786.
|
| REF 131 |
Hypoxia-responsive microRNA-101 promotes angiogenesis via heme oxygenase-1/vascular endothelial growth factor axis by targeting cullin 3. Antioxid Redox Signal. 2014 Dec 20;21(18):2469-82.
|
| REF 132 |
Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway. J Biol Chem. 1997 Mar 28;272(13):8581-93.
|
| REF 133 |
Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization. Cell Physiol Biochem. 2004;14(4-6):351-60.
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| REF 134 |
HSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivo. J Biol Chem. 2003 May 9;278(19):17299-306.
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| REF 135 |
Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex. J Biol Chem. 2001 Dec 7;276(49):45791-9.
|
| REF 136 |
Combination of pan-histone deacetylase inhibitor and autophagy inhibitor exerts superior efficacy against triple-negative human breast cancer cells. Mol Cancer Ther. 2012 Apr;11(4):973-83.
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| REF 137 |
Involvement of heat shock factor 1 in statin-induced transcriptional upregulation of endothelial thrombomodulin. Circ Res. 2008 Aug 15;103(4):369-77.
|
| REF 138 |
Role of the Per/Arnt/Sim domains in ligand-dependent transformation of the aryl hydrocarbon receptor. J Biol Chem. 2008 Nov 21;283(47):32995-3005.
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| REF 139 |
The immunophilin-like protein XAP2 regulates ubiquitination and subcellular localization of the dioxin receptor. J Biol Chem. 2000 Dec 29;275(52):41317-24.
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| REF 140 |
Tom70 mediates activation of interferon regulatory factor 3 on mitochondria. Cell Res. 2010 Sep;20(9):994-1011.
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| REF 141 |
Hsp90alpha recruited by Sp1 is important for transcription of 12(S)-lipoxygenase in A431 cells. J Biol Chem. 2005 Oct 28;280(43):36283-92.
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| REF 142 |
A comprehensive resource of interacting protein regions for refining human transcription factor networks. PLoS One. 2010 Feb 24;5(2):e9289.
|
| REF 143 |
Endogenous human MDM2-C is highly expressed in human cancers and functions as a p53-independent growth activator. PLoS One. 2013 Oct 11;8(10):e77643.
|
| REF 144 |
Hispolon promotes MDM2 downregulation through chaperone-mediated autophagy. Biochem Biophys Res Commun. 2010 Jul 16;398(1):26-31.
|
| REF 145 |
Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1. J Mol Biol. 2004 Mar 12;337(1):115-28.
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| REF 146 |
Mixed Hsp90-cochaperone complexes are important for the progression of the reaction cycle. Nat Struct Mol Biol. 2011 Jan;18(1):61-6.
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| REF 147 |
Balance between folding and degradation for Hsp90-dependent client proteins: a key role for CHIP. Biochemistry. 2010 Sep 7;49(35):7428-38.
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| REF 148 |
Ligand discrimination by TPR domains. Relevance and selectivity of EEVD-recognition in Hsp70 x Hop x Hsp90 complexes. J Biol Chem. 2002 May 31;277(22):19265-75.
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| REF 149 |
Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1. Mol Cell. 2002 Dec;10(6):1307-18.
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| REF 150 |
Mutations that increase both Hsp90 ATPase activity in vitro and Hsp90 drug resistance in vivo. Biochim Biophys Acta. 2010 May;1803(5):575-83.
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| REF 151 |
17-AAG, an Hsp90 inhibitor, causes kinetochore defects: a novel mechanism by which 17-AAG inhibits cell proliferation. Oncogene. 2006 Jul 13;25(30):4133-46.
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| REF 152 |
Calcyclin Binding Protein/Siah-1 Interacting Protein Is a Hsp90 Binding Chaperone. PLoS One. 2016 Jun 1;11(6):e0156507.
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| REF 153 |
Structural basis for phosphorylation-dependent recruitment of Tel2 to Hsp90 by Pih1. Structure. 2014 Jun 10;22(6):805-18.
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| REF 154 |
Mutation of the Ser18 phosphorylation site on the sole Saccharomyces cerevisiae UCS protein, She4, can compromise high-temperature survival. Cell Stress Chaperones. 2017 Jan;22(1):135-141.
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