Protein-Protein Interaction Details
| Protein General Information (TTD Target) | Top | ||||
|---|---|---|---|---|---|
| Full Name | Peroxisome proliferator-activated receptor delta (PPARD) | Clinical trial | Target Info | ||
| UniProt ID | PPARD_HUMAN | ||||
| Gene Name | PPARD | ||||
| Gene ID | 5467 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Successful Target(s) | Heat shock protein 90 alpha (HSP90A) | Target Info | PPI Info | [1] | |
| Retinoic acid receptor RXR-gamma (RXRG) | Target Info | PPI Info | [2] | ||
| Retinoic acid receptor RXR-alpha (RXRA) | Target Info | PPI Info | [3] | ||
| Retinoic acid receptor RXR-beta (RXRB) | Target Info | PPI Info | [2] | ||
| Interacting Clinical trial Target(s) | Histone deacetylase 2 (HDAC2) | Target Info | PPI Info | [4] | |
| Histone deacetylase 3 (HDAC3) | Target Info | PPI Info | [4] | ||
| Histone acetyltransferase p300 (EP300) | Target Info | PPI Info | [5] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Cell. 2012 Aug 31;150(5):987-1001. | ||||
| REF 2 | Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. Mol Cell Proteomics. 2005 Feb;4(2):205-13. | ||||
| REF 3 | Ligand modulated antagonism of PPARgamma by genomic and non-genomic actions of PPARdelta. PLoS One. 2009 Sep 16;4(9):e7046. | ||||
| REF 4 | The peroxisome proliferator-activated receptor delta, an integrator of transcriptional repression and nuclear receptor signaling. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2613-8. | ||||
| REF 5 | A simple method to screen ligands of peroxisome proliferator-activated receptor delta. Eur J Pharm Sci. 2006 Dec;29(5):355-60. | ||||
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