Protein-Protein Interaction Details
Protein General Information (TTD Target) | Top | ||||
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Full Name | Stress-activated protein kinase JNK2 (JNK2) | Preclinical | Target Info | ||
UniProt ID | MK09_HUMAN | ||||
Gene Name | MAPK9 | ||||
Gene ID | 5601 |
Interacting TTD Target Information | Top | ||||
---|---|---|---|---|---|
Interacting Successful Target(s) | Epidermal growth factor receptor (EGFR) | Target Info | PPI Info | [1] | |
Interacting Preclinical Target(s) | Stress-activated protein kinase JNK2 (JNK2) | Target Info | PPI Info | [2] | |
Interacting Patented-recorded Target(s) | JNK-interacting protein 1 peptide (pepJIP1) | Target Info | PPI Info | [3] | |
Interacting Discontinued Target(s) | Transcription factor AP-1 (JUN) | Target Info | PPI Info | [4] | |
Interacting Literature-reported Target(s) | Dual specificity protein phosphatase 10 (DUSP10) | Target Info | PPI Info | [5] |
References | Top | ||||
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REF 1 | The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat Methods. 2014 May;11(5):585-92. | ||||
REF 2 | c-Jun N-terminal kinase 1 phosphorylates Myt1 to prevent UVA-induced skin cancer. Mol Cell Biol. 2009 Apr;29(8):2168-80. | ||||
REF 3 | A mammalian scaffold complex that selectively mediates MAP kinase activation. Science. 1998 Sep 11;281(5383):1671-4. | ||||
REF 4 | c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions. Cell. 1996 Nov 29;87(5):929-39. | ||||
REF 5 | Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Cell Rep. 2016 Nov 22;17(9):2488-2501. |
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