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| Protein General Information |
Top |
| Full Name |
Protein numb homolog (NUMB)
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| UniProt ID |
NUMB_HUMAN
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| Gene Name |
NUMB
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| Gene ID |
8650
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| Interacting TTD Target Information |
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| Interacting Clinical trial Target(s) |
Ubiquitin-protein ligase E3 Mdm2 (MDM2) |
Target Info
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PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
E3 ubiquitin protein ligase Itchy (ITCH) |
Target Info
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PPI Info
|
[2] |
| References |
Top |
| REF 1 |
Mammalian Numb is a target protein of Mdm2, ubiquitin ligase. Biochem Biophys Res Commun. 2003 Mar 21;302(4):869-72.
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| REF 2 |
Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain. J Biol Chem. 2003 Jun 20;278(25):23196-203.
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