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| Protein General Information |
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| Full Name |
Partner and localizer of BRCA2 (PALB2)
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| UniProt ID |
PALB2_HUMAN
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| Gene Name |
PALB2
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| Gene ID |
79728
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| Interacting TTD Target Information |
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| Interacting Literature-reported Target(s) |
Breast cancer type 2 susceptibility protein (BRCA2) |
Target Info
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PPI Info
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[1] |
| Interacting Clinical trial Target(s) |
DNA repair protein RAD51 homolog 1 (RAD51) |
Target Info
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PPI Info
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[2] |
| References |
Top |
| REF 1 |
PALB2 is an integral component of the BRCA complex required for homologous recombination repair. Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7155-60.
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| REF 2 |
Compromised BRCA1-PALB2 interaction is associated with breast cancer risk. Oncogene. 2017 Jul 20;36(29):4161-4170.
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